Abstract:
A memory module comprises a plurality of semiconductor memory devices each having a termination circuit for a command/address bus. The semiconductor memory devices are formed in a substrate of the memory module, and they operate in response to a command/address signal, a data signal, and a termination resistance control signal.
Abstract:
The present invention relates to a compound inhibiting HF-1 activity, a preparation method of the same, and a pharmaceutical composition comprising the same as an active ingredient. The compound of the present invention demonstrates anticancer activity not by non-selective cytotoxicity but by inhibiting the activity of HIF-1, the transcription factor playing an important role in cancer cell growth and metastasis. Accordingly, the compound or the pharmaceutically acceptable salt thereof according to the present invention inhibits HIF-1 activity, and therefore can be used as a therapeutic agent for solid tumors such as colon cancer, liver cancer, stomach cancer and breast cancer. In addition, the compound or the pharmaceutically acceptable salt thereof according to the present invention can be used as an active ingredient for a therapeutic agent for diabetic retinopathy or arthritis which may become worse when hypoxia-induced VEGF expression by HIF-1 increases.
Abstract:
A data receiver includes a first buffer circuit and a second buffer circuit. The first buffer circuit varies a resistance of a data path and a resistance of a reference voltage path based on a plurality of control signals, and adjusts a voltage level of an input data signal and a level of a reference voltage to generate an internal data signal and an internal reference voltage based on the varied resistance of the data path and the varied resistance of the reference voltage path. The second buffer circuit compares the internal data signal with the internal reference voltage to generate a data signal.
Abstract:
A semiconductor memory device includes an input data delay time adjustor for varying an input delay time, selecting one bit of a n-bit input data, delaying the selected one bit by the input delay time and outputting the delayed bit, in response to a control signal during an input data delay test operation; and an output data delay time adjustor for varying an output delay time, selecting one bit of a m-bit output data, delaying the selected one bit by the output delay time and outputting the delayed bit, in response to the control signal during an output data delay test operation, wherein the input data delay time adjustor is arranged for n-bit input data, and wherein the output data delay time adjustor is arranged for m-bit output data.
Abstract:
Disclosed herein are an HIF-1 inhibitor, a method for the preparation thereof, and a pharmaceutical composition comprising the same as an active ingredient. The HIF-1 inhibitor shows anticancer activity thanks to the inhibition activity against HIF-1, a transcription factor which plays an important role in the growth and metastasis of cancer, but not to general cytotoxicity. Thus, the HIF-inhibitor and a pharmaceutically acceptable salt thereof can be used as a therapeutic for various cancers such as liver cancer; stomach cancer and breast cancer. Also, the compound having inhibition activity against HIF-1 is useful in the treatment of diabetic retinopathy and arthritis, which are aggravated by HIF-1-mediated VEGF expression.
Abstract:
The present invention relates to geldanamycin derivatives, benzoquinone ansamycin biosynthesized by gene manipulation of Streptomyces hygroscopicus subsp. duamyceticus and the method producing them, more particularly to a geldanamycin O-carbamoyl transferase gene(gel8)-inactive mutant, the method producing it and geldanamycin derivatives, 4,5-dihydro-7-O-descarbamoyl-7-hydroxy geldanamycin and 4,5-dihydro-7-O-descarbamoyl-7-hydroxy-17-O-demethyl geldanamycin. Since geldanamycin derivatives of the present invention suppress Hsp90 like geldanamycin, they can effectively be used for antibiotic, antifungal, antiviral, anti-inflammatory and antitumor agents and an immune suppressant.
Abstract:
A memory module and a method of mounting memory devices on a PCB to form the memory module substantially reduce unnecessary routing space and improve signal attenuation characteristics. In the method of mounting and sequentially connecting at least two memory devices on a printed circuit board (PCB) having an axis of elongation to form a memory module, at least one of the memory devices is mounted on at least one face of the PCB so that a base line along an longitudinal axis of the at least one memory device lies at an acute angle with respect to the axis of elongation of the PCB.
Abstract:
The present invention discloses a memory module and a method of arranging a signal line of the same. The method of arranging a signal line of a memory module comprises: classifying a plurality of memories into a first group including an odd number of memories and a second group including an even number of memories; arranging first branch points corresponding to the plurality of memories and respectively connecting the first branch points to the plurality of memories through first signal lines; arranging a second branch point located at a middle of the second group for respectively connecting between the first branch points adjacent to each other of the second group and between the first branch points adjacent to the second branch points and the second branch point through second signal lines; arranging a third branch point located at a middle of the second group, receiving an external signal, and connecting the third branch point and the second branch point of the second group through a third signal line; and connecting between the second branch point of the second group and the first branch point of the first group through a fourth signal line.
Abstract:
The disclosure concerns novel use of diterpene compound as a therapeutic agent of inlfammation, immune disease or cancer. More particularly, the present invention relates to novel use of diterpene compound that include kamebanin, kamebacetal A, kamebakaurin, and exisanin A, which would be effective for the treatment inflammation, immune disease or cancer by inhibiting the production of nitric oxide, prostaglandin, and TNF-a1 through the suppression of NF-k B activity.
Abstract:
A ball grid array (BGA) package test module includes BGA packages, a module board, and test architecture for use in testing the BGA packages while they are mounted to the module board. The test architecture of the BGA package test module includes package test signal lines connected to solder balls of the BGA packages as extending along a bottom surface of the BGA packages, board test signal lines extending along the module board, and electrical junctions that interconnect the package and board test signal lines. Signals from the BGA packages can be picked up by the probe of a testing apparatus via the board test signal lines. The present invention is advantageous in that it minimizes the effect of stubbing by the test signal lines when the memory module is operating.