公开(公告)号：US07897916B2

公开(公告)日：2011-03-01

申请号：US10598194

申请日：2005-02-23

Applicant: Michael Sudakov ,  Li Ding

Inventor： Michael Sudakov ,  Li Ding

IPC: H01J49/42

CPC classification number: H01J49/40 ,  H01J49/004 ,  H01J49/423

Abstract: A tandem linear ion trap and time-of-flight mass spectrometer, where the ion trap has a straight central axis orthogonal to the flight path of the mass spectrometer. The ion trap comprises a set of electrodes, (401, 403, 402, 404) at least one of the electrodes has a slit for ejecting ions towards the mass spectrometer; a set of DC voltage supplies (+V, −V, V1, V2) to provide discrete DC levels and a number of fast electronic switches (409) for connecting/disconnecting the DC supplies to at least two of the electrodes; a neutral gas filling the ion trap and a digital controller to provide a switching procedure of ion trapping, manipulation with ions, cooling and including a state at which all ions are ejected from the ion trap towards the mass spectrometer.

Abstract translation: 串联线性离子阱和飞行时间质谱仪，其中离子阱具有与质谱仪的飞行路径正交的直的中心轴。 离子阱包括一组电极（401,403,402,404），至少一个电极具有用于向质谱仪喷射离子的狭缝; 一组直流电压源（+ V，-V，V1，V2）以提供离散DC电平以及用于将DC电源连接/断开至少两个电极的多个快速电子开关（409） 填充离子阱的中性气体和数字控制器，以提供离子捕获，用离子的操作，冷却和包括从离子阱向质谱仪喷射所有离子的状态的切换过程。

公开(公告)号：US07893401B2

公开(公告)日：2011-02-22

申请号：US12158458

申请日：2006-12-20

Applicant: Li Ding

Inventor： Li Ding

IPC: H01J49/04

CPC classification number: H01J49/062 ,  H01J49/0481 ,  H01J49/164

Abstract: A mass spectrometer has a pulsed ion source, a first ion trap (10) for trapping ions generated by the pulsed ion source and for locating trapped ions for subsequent ejection from the first ion trap. A pulse of cooling gas is introduced into the first ion trap (10) at a peak pressure suitable for enabling the first ion trap (10) to trap ions. A turbomolecular pump (17) reduces the pressure of cooling gas before the trapped ions are ejected from the first ion trap (1) towards a second ion trap (20) for analysis. The pulsed ion source has a sample plate (14) which forms an end wall of the first ion trap (10).

Abstract translation: 质谱仪具有脉冲离子源，第一离子阱（10），用于捕获由脉冲离子源产生的离子，并用于定位捕获的离子用于随后从第一离子阱排出。 将冷却气体的脉冲以适于使第一离子阱（10）捕获离子的峰值压力引入到第一离子阱（10）中。 涡轮分子泵（17）在被捕获的离子从第一离子阱（1）向第二离子阱（20）排出之前降低冷却气体的压力，用于分析。 脉冲离子源具有形成第一离子阱（10）的端壁的样品板（14）。

公开(公告)号：US20100243216A1

公开(公告)日：2010-09-30

申请号：US12475527

申请日：2009-05-31

Applicant: ZHI-YONG ZHOU ,  QIAO-LI DING ,  HAI-BING CAO

Inventor： ZHI-YONG ZHOU ,  QIAO-LI DING ,  HAI-BING CAO

IPC: F28D15/00 ,  F28F1/10

CPC classification number: H01L23/473 ,  H01L2924/0002 ,  H01L2924/00

Abstract: A liquid-cooling device includes a heat exchanger defining a cavity therein and a liquid-guiding component received in the cavity. The liquid-guiding component includes a body and a fixing portion extending from the body and fixed to the heat exchanger. A first liquid passage is defined through the body and a second liquid passage is formed between the body and an inner sidewall of the heat exchanger surrounding the cavity. The first liquid passage is in fluid communication with the second liquid passage via a bottom of the cavity. An outlet and an inlet are formed at an end of the liquid-guiding component and in fluid communication with the first and second liquid passages. Liquid flows in the cavity of the heat exchanger via the first liquid passage and has a sufficient contact with the inner sidewall of the heat exchanger.

Abstract translation: 液体冷却装置包括在其中限定空腔的热交换器和容纳在空腔中的液体引导部件。 液体引导部件包括主体和从主体延伸并固定到热交换器的固定部。 第一液体通道被限定穿过主体，并且第二液体通道形成在主体与围绕空腔的热交换器的内侧壁之间。 第一液体通道经由腔的底部与第二液体通道流体连通。 出口和入口形成在液体引导部件的端部处并与第一和第二液体通道流体连通。 液体经由第一液体通道在热交换器的空腔中流动，并且与热交换器的内侧壁具有充分的接触。

公开(公告)号：US07789910B2

公开(公告)日：2010-09-07

申请号：US11948298

申请日：2007-11-30

Applicant: Wayne H. Knox ,  Li Ding ,  Jay F. Kunzler ,  Dharmendra Jani ,  Candido D. Pinto

Inventor： Wayne H. Knox ,  Li Ding ,  Jay F. Kunzler ,  Dharmendra Jani ,  Candido D. Pinto

IPC: A61F2/16

CPC classification number: A61F2/1613 ,  A61B18/20 ,  A61F2/14 ,  A61F2/16 ,  A61F2/1627 ,  A61F2/1635 ,  B29D11/00461 ,  B29D11/023 ,  C08J7/12 ,  C08J7/123 ,  G02C2202/14

Abstract: A method for modifying the refractive index of an optical, polymeric material. The method comprises irradiating select regions of the optical, polymeric material with a focused, visible or near-IR laser having a pulse energy from 0.05 nJ to 1000 nJ. The irradiation results in the formation of refractive optical structures, characterized by a change in refractive index, exhibit little or no scattering loss, and exhibit no significant differences in the Raman spectrum with respect to the non-irradiated optical, polymeric material. The method can be used to modify the refractive index of an intraocular lens following the surgical implantation of the intraocular lens in a human eye. The invention is also directed to an optical device comprising refractive optical structures, wherein the refractive structures are characterized by a change in refractive index, exhibit little or no scattering loss, and exhibit no significant differences in the Raman spectrum with respect to the non-irradiated optical, polymeric material.

Abstract translation: 用于改变光学聚合物材料的折射率的方法。 该方法包括用具有0.05nJ至1000nJ的脉冲能量的聚焦，可见或近红外激光照射光学聚合物材料的选择区域。 照射导致折射光学结构的形成，其特征在于折射率的变化，显示很少或没有散射损失，并且在拉曼光谱方面相对于未照射的光学聚合物材料没有显着差异。 该方法可以用于在人眼中手术植入人工晶状体后修改眼内透镜的折射率。 本发明还涉及一种包括折射光学结构的光学器件，其中折射结构的特征在于折射率的变化，表现出很少的或没有散射损耗，并且在拉曼光谱方面相对于未辐照的表现没有显着的差异 光学，聚合材料。

公开(公告)号：US20100139894A1

公开(公告)日：2010-06-10

申请号：US12436785

申请日：2009-05-07

Applicant: ZHI-YONG ZHOU ,  QIAO-LI DING

Inventor： ZHI-YONG ZHOU ,  QIAO-LI DING

IPC: F28D15/04

CPC classification number: F28D15/046 ,  H01L2924/0002 ,  H01L2924/00

Abstract: A heat sink includes a heat spreader for absorbing heat from a heat-generating source, a tank covering on the heat spreader and hermetically engaging with the heat spreader, a first wick layer formed on an inner face of the tank, a second wick layer formed on an inner face of the heat spreader, and a supporting member located between the tank and the heat spreader. A chamber is defined between the tank and the heat spreader and contains working fluid therein. The supporting member is arranged in a wave shape and supports the first wick layer and the second wick layer.

Abstract translation: 散热器包括用于从发热源吸收热量的散热器，覆盖在散热器上并与散热器密封接合的容器，形成在罐的内表面上的第一灯芯层，形成的第二灯芯层 在散热器的内表面上，以及位于罐和散热器之间的支撑构件。 在罐和散热器之间限定一个室，并在其中包含工作流体。 支撑构件布置成波形，并且支撑第一灯芯层和第二灯芯层。

公开(公告)号：US20100005429A1

公开(公告)日：2010-01-07

申请号：US12166630

申请日：2008-07-02

Applicant: Jindrich Zejda ,  Narender Hanchate ,  Rupesh Nayak ,  Li Ding

Inventor： Jindrich Zejda ,  Narender Hanchate ,  Rupesh Nayak ,  Li Ding

IPC: G06F17/50

CPC classification number: G06F17/5036 ,  G06F17/505

Abstract: One embodiment of the present invention provides systems and techniques for generating a transistor-level description of a subcircuit. A user may want to simulate a subcircuit in a circuit using a transistor-level simulator, and one or more cells in the subcircuit may need to be sensitized so that the cells are in a desired state when the subcircuit is simulated. An embodiment modifies the subcircuit by inserting analog switches in front of the cells that need to be sensitized, so that the analog switches can be used to apply a sensitization sequence to the cells during the transistor-level simulation. The embodiment can then generate a transistor-level description of the modified subcircuit. Next, the transistor-level description of the subcircuit can be stored, thereby enabling the transistor-level simulator to simulate the subcircuit.

Abstract translation: 本发明的一个实施例提供了用于产生子电路的晶体管级描述的系统和技术。 用户可能需要使用晶体管级模拟器来模拟电路中的分支电路，并且子电路中的一个或多个单元可能需要被敏化，使得当模拟子电路时，单元格处于期望状态。 实施例通过将模拟开关插入需要敏化的单元前面来修改子电路，使得模拟开关可用于在晶体管级仿真期间向单元施加致敏序列。 然后，该实施例可以生成修改后的子电路的晶体管级描述。 接下来，可以存储子电路的晶体管级描述，从而使晶体管级模拟器能够模拟子电路。

公开(公告)号：US20090294655A1

公开(公告)日：2009-12-03

申请号：US12298968

申请日：2007-04-13

Applicant: Chuanfan Ding ,  Li Ding

Inventor： Chuanfan Ding ,  Li Ding

IPC: B01D59/44 ,  H01J49/00

CPC classification number: H01J49/4225 ,  H01J49/004 ,  H01J49/065 ,  H01J49/4235

Abstract: The invention “Ion Trap Array (ITA)” pertains generally to the field of ion storage and analysis technologies, and particularly to the ion storing apparatus and mass spectrometry instruments which separate ions by its character such as mass-to-charge ratio. The aim of this invention is providing an apparatus for ion storage and analysis comprising at least two or more rows of parallel placed electrode array wherein each electrode array includes at least two or more parallel bar-shaped electrodes, by applying different phase of alternating current voltages on different bar electrodes to create alternating electric fields inside the space between two parallel electrodes of different rows of electrode arrays, multiple linear ion trapping fields paralleled constructed in the space between the different rows of electrode arrays which are open to adjacent each other without a real barrier. This invention also provides a method for ion storage and analysis involving with the trapping, cooling and mass-selected analyzing of ions by this apparatus mentioned which constructs multiple conjoint linear ion trapping fields in the space between the different rows of electrode arrays

Abstract translation: 本发明“离子阱阵列（ITA）”一般涉及离子存储和分析技术领域，特别涉及离子存储装置和质谱仪器，它们通过诸如质荷比的特性分离离子。 本发明的目的是提供一种用于离子存储和分析的装置，其包括至少两行或多行平行放置的电极阵列，其中每个电极阵列包括至少两个或更多个平行的棒状电极，通过施加不同相位的交流电压 在不同的棒电极上在不同行电极阵列的两个平行电极之间的空间内部产生交替电场，多个线性离子俘获场平行地构造在电极阵列的不同行之间的空间中，这些空间彼此相邻而没有实际 屏障。 本发明还提供一种离子存储和分析的方法，其涉及通过所述装置进行的捕获，冷却和质量选择的离子分析，其构造了在不同行电极阵列之间的空间中的多个联合线性离子捕获场

公开(公告)号：US20090287306A1

公开(公告)日：2009-11-19

申请号：US12380892

申请日：2009-03-04

Applicant: Thomas Smith ,  Wayne H. Knox ,  Li Ding ,  Dharmendra Jani ,  Jeffrey G. Linhardt

Inventor： Thomas Smith ,  Wayne H. Knox ,  Li Ding ,  Dharmendra Jani ,  Jeffrey G. Linhardt

IPC: A61F2/16 ,  B29D11/00 ,  A61F2/14

CPC classification number: A61F9/00804 ,  A61F2/1451 ,  A61F2/1627 ,  A61F2/1635 ,  A61L27/50 ,  A61L27/52 ,  A61L2430/16 ,  B29D11/00009 ,  G02C2202/14

Abstract: A method for modifying the refractive index of an optical, hydrogel polymeric material. The method comprises irradiating predetermined regions of an optical, polymeric material with a laser to form refractive structures. To facilitate the formation of the refractive structures the optical, hydrogel polymeric material comprises a photosensitizer. The presence of the photosensitizer permits one to set a scan rate to a value that is at least fifty times greater than a scan rate without the photosensitizer in the material, yet provides similar refractive structures in terms of the observed change in refractive index. Alternatively, the photosensitizer in the polymeric material permits one to set an average laser power to a value that is at least two times less than an average laser power without the photosensitizer in the material, yet provide similar refractive structures.

Abstract translation: 一种用于改变光学水凝胶聚合物材料的折射率的方法。 该方法包括用激光照射光学聚合材料的预定区域以形成折射结构。 为了促进折射结构的形成，光学水凝胶聚合物材料包含光敏剂。 光敏剂的存在允许将扫描速率设置为比材料中没有光敏剂的扫描速率至少大五十倍的值，但是根据观察到的折射率变化提供相似的折射结构。 或者，聚合物材料中的光敏剂允许将平均激光功率设置为比平均激光功率小至少两倍的值，而不需要材料中的光敏剂，但是提供类似的折射结构。

公开(公告)号：US20090268476A1

公开(公告)日：2009-10-29

申请号：US12131111

申请日：2008-06-01

Applicant: ZHI-YONG ZHOU ,  QIAO-LI DING

Inventor： ZHI-YONG ZHOU ,  QIAO-LI DING

IPC: F21V29/00

CPC classification number: F21V29/004 ,  F21K9/00 ,  F21V29/51 ,  F21V29/763 ,  F21Y2115/10

Abstract: A heat dissipation device includes a heat conductive member, a fin unit coupled to a bottom surface of the heat conductive member and a plurality of LED modules attached to a top surface of the heat conductive member. The heat conductive member consists of a first plate, a second plate parallel to the first plate and a plurality of posts sandwiched between the first and second plates. Peripheries of the first and second plate are in a hermetical conjunction with each other to form a chamber containing a phase-changeable working fluid therein. The first and second plates therein define a plurality of through orifices. The posts each define therein a screwed orifice which is in alignment with corresponding through orifices of the first and second plates respectively and threadedly receives a screw extending through the LED module.

Abstract translation: 散热装置包括导热构件，耦合到导热构件的底表面的翅片单元和附接到导热构件的顶表面的多个LED模块。 导热构件包括第一板，平行于第一板的第二板和夹在第一板和第二板之间的多个柱。 第一和第二板的周边彼此密封结合以形成其中包含相变工作流体的室。 其中的第一和第二板限定多个通孔。 所述柱分别在其中限定有螺纹孔口，所述螺纹孔口分别对应于所述第一和第二板的对应的通孔，并且螺纹地容纳延伸穿过所述LED模块的螺钉。

公开(公告)号：US07608704B2

公开(公告)日：2009-10-27

申请号：US11378616

申请日：2006-03-20

Applicant: Henry Yue ,  Monique G. Yao ,  Ameena R. Gandhi ,  Mariah R. Baughn ,  Anita Swarnakar ,  Narinder Chawla ,  Madhusudan M. Sanjanwala ,  Michael Thorton ,  Vicki S. Elliott ,  Yan Lu ,  Kimberly J. Gietzen ,  Neil Burford ,  Li Ding ,  April J. A. Hafalia ,  Y. Tom Tang ,  Olga Bandman ,  Bridget A. Warren ,  Cynthia D. Honchell ,  Dyung Aina M. Lu ,  Kavitha Thangavelu ,  Sally Lee ,  Yuming Xu ,  Junming Yang ,  Preeti G. Lal ,  Bao Tran ,  Craig H. Ison ,  Brendan M. Duggan ,  Stephanie K. Sapperstein

Inventor： Henry Yue ,  Monique G. Yao ,  Ameena R. Gandhi ,  Mariah R. Baughn ,  Anita Swarnakar ,  Narinder Chawla ,  Madhusudan M. Sanjanwala ,  Michael Thorton ,  Vicki S. Elliott ,  Yan Lu ,  Kimberly J. Gietzen ,  Neil Burford ,  Li Ding ,  April J. A. Hafalia ,  Y. Tom Tang ,  Olga Bandman ,  Bridget A. Warren ,  Cynthia D. Honchell ,  Dyung Aina M. Lu ,  Kavitha Thangavelu ,  Sally Lee ,  Yuming Xu ,  Junming Yang ,  Preeti G. Lal ,  Bao Tran ,  Craig H. Ison ,  Brendan M. Duggan ,  Stephanie K. Sapperstein

IPC: C07H21/04 ,  C12N15/00 ,  C12P21/04

CPC classification number: C12N15/1055 ,  A61K39/3955 ,  A61K47/64 ,  A61K47/643 ,  A61K2039/505 ,  C07K14/47 ,  C07K14/4711 ,  C07K14/4713 ,  C07K16/18 ,  C07K2317/24 ,  C07K2317/54 ,  C07K2317/55 ,  C07K2317/622 ,  C07K2317/75 ,  C07K2317/76 ,  G01N33/5023

Abstract: The invention provides human secreted proteins (SECP) and polynucleotides which identify and encode SECP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.

Abstract translation: 本发明提供鉴定和编码SECP的人分泌蛋白（SECP）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供用于诊断，治疗或预防与SECP异常表达相关的疾病的方法。