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公开(公告)号:US20240272018A1
公开(公告)日:2024-08-15
申请号:US18565719
申请日:2022-05-31
Applicant: UNIVERSITY OF KANSAS
Inventor: Cory BERKLAND , Jonathan MILLER
CPC classification number: G01L1/122 , A61B5/05 , H01F7/081 , A61B2562/0223
Abstract: Described herein are magnetic sensors (e.g., force sensors) as well as methods of making and using thereof The magnetic sensors can employ a soft magnetic composite (e.g a composite comprising a population of magnetic particles dispersed within an elastomeric resin) paired with a magnetometer. These sensors can overcome many of the traditional shortcomings that have hampered the effectiveness of existing compression sensors in certain applications, including large size, a lack of 3-dimensional sensing capacity, need for sensors to incorporate rigid components, and/or signal quality issues associated with the orientation or deformation of soft composites under compression.
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公开(公告)号:US20240269239A1
公开(公告)日:2024-08-15
申请号:US18274166
申请日:2022-01-27
Applicant: University of Kansas
Inventor: Kyle APLEY , Mark FARRELL , Cory BERKLAND
CPC classification number: A61K38/28 , A61K38/48 , A61K39/0008 , A61K47/545 , A61K47/549 , A61K47/60 , A61P3/10 , C07D249/04 , C07H15/26 , C07K14/62
Abstract: The present disclosure provides conjugates, methods of making the same, and uses thereof. The conjugates of the present technology are useful in inducing anergy in insulin-binding B cells.
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公开(公告)号:US20240257524A1
公开(公告)日:2024-08-01
申请号:US18426303
申请日:2024-01-29
Applicant: University of Kansas
Inventor: Haiyang Chao , Saket Gowravaram Navalur , Zhenghao Lin
IPC: G06V20/52 , G06V10/764 , G06V20/17 , G06V20/40
CPC classification number: G06V20/52 , G06V10/764 , G06V20/17 , G06V20/44
Abstract: The present disclosure provides systems and methods for extracting information from image data captured using an unmanned aircraft system (UAS). The disclosed systems and methods may capture image data using an imaging device mounted to the UAS, which may include a plurality of images of an environment. Each image may be associated with a particular area of the environment and a timestamp. The imagery may be used to construct one or more multi-temporal orthomosaics. The disclosed systems and methods may generate information representative of a dynamic evolution of an event impacting the environment over time based on the multi-temporal orthomosaic(s). The systems and methods may also calculate a rate of spread (ROS) of the event based on the information representative dynamic evolution of an event impacting the environment over time. In an additional aspect, techniques for synchronizing image data captured by the UAS to calibrated image data are disclosed.
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公开(公告)号:US20240252610A1
公开(公告)日:2024-08-01
申请号:US18562170
申请日:2022-05-23
Applicant: UNIVERSITY OF KANSAS , UNIVERSITY OF MARYLAND, BALTIMORE
Inventor: Wendy L. PICKING , William D. PICKING , Robert K. ERNST
IPC: A61K39/104 , A61K39/00 , A61K39/02 , A61K39/112 , A61P37/04 , C07K14/195 , C07K14/21 , C07K14/235 , C07K14/24 , C07K14/245 , C07K14/25 , C07K14/255 , C07K14/28
CPC classification number: A61K39/104 , A61K39/0208 , A61K39/0275 , A61K39/0283 , A61K39/0291 , A61K39/099 , A61P37/04 , C07K14/195 , C07K14/21 , C07K14/235 , C07K14/24 , C07K14/245 , C07K14/25 , C07K14/255 , C07K14/28 , A61K2039/55566 , A61K2039/55572 , A61K2039/55583
Abstract: Disclosed are compositions comprising a fusion polypeptide comprising i) a fusion of a needle tip protein or an antigenic fragment thereof and/or a translocator protein or an antigenic fragment thereof from a Type III secretion system (T3SS) of a Gram negative bacteria and ii) the A1 subunit of the labile toxin (LTA1) from enterotoxigenic Escherichia coli or cholera toxin, and methods of their use.
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公开(公告)号:US12037544B2
公开(公告)日:2024-07-16
申请号:US17864126
申请日:2022-07-13
Applicant: CONOCOPHILLIPS COMPANY , University of Kansas
Inventor: Ahmad Moradi-Araghi , Min Cheng , Riley B. Needham , James H Hedges , Ramesh S Sarathi , Faye L Scully , Terry M Christian , Huili Guan , Cory Berkland , Jenn-Tai Liang
IPC: C09K8/588 , E21B33/138 , E21B43/16
CPC classification number: C09K8/588 , E21B33/138 , E21B43/16
Abstract: The invention is directed to stable and labile crosslinked water swellable polymeric microparticles that can be further gelled by covalent crosslinking in a transamidation reaction, methods for making same, and their various uses in the hygiene and medical arts, gel electrophoresis, packaging, agriculture, the cable industry, information technology, in the food industry, papermaking, use as flocculation aids, and the like. More particularly, the invention relates to a composition comprising expandable polymeric microparticles having labile crosslinkers and stable crosslinkers, said microparticle mixed with a fluid and an unreacted tertiary crosslinker comprising PEI or other polyamine based tertiary crosslinker that is capable of further crosslinking the microparticle on degradation of the labile crosslinker and swelling of the particle, so as to form a stable gel. A particularly important use is as an injection fluid in petroleum production, where the expandable polymeric microparticles are injected into a well and when the heat and/or pH of the well cause degradation of the labile crosslinker and when the microparticle expands, the tertiary crosslinker crosslinks the polymer to form a stable gel, thus diverting water to lower permeability regions and improving oil recovery.
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公开(公告)号:US12024536B2
公开(公告)日:2024-07-02
申请号:US17863135
申请日:2022-07-12
Applicant: UNIVERSITY OF KANSAS
Inventor: Brian S. J. Blagg , Bhaskar Reddy Kusuma , Teather Sundstrom
IPC: C07H15/207 , C07C211/17 , C07H15/203
CPC classification number: C07H15/207 , C07C211/17 , C07H15/203
Abstract: Hsp90 C-terminal inhibitors and pharmaceutical compositions containing such compounds are provided. The compounds of the disclosure are useful for the treatment and/or prevention of neurodegenerative disorders such as diabetic peripheral neuropathy.
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公开(公告)号:US12000949B2
公开(公告)日:2024-06-04
申请号:US17269077
申请日:2019-09-21
Applicant: University of Kansas , THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE
Inventor: Gerald Brandon Ravenscroft , Patrick M. McCormick , Shannon D. Blunt , Erik S. Perrins , Justin G. Metcalf
CPC classification number: G01S7/006 , G01S13/347 , H04L27/2626
Abstract: Systems, methods, and computer-readable storage media for generating, transmitting, and utilizing a composite radar and communication waveform are disclosed. The composite radar and communication waveform may facilitate radar detection and data communication operations and may be generated from a frequency modulated (FM) radar waveform and a communication signal. In an aspect, the composite radar and communication waveform may be generated by iteratively executing a shaping process against the FM radar waveform and the communication signal until a first stop criterion is satisfied to produce an initial composite radar and communication waveform having the communication signal embedded therein, and then iteratively executing an enhancement process against the initial composite radar waveform and the communication signal until a second stop criterion is satisfied to produce a final composite radar and communication waveform suitable for both radar detection and data communication operations.
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公开(公告)号:US11939291B2
公开(公告)日:2024-03-26
申请号:US17226359
申请日:2021-04-09
Applicant: University of Kansas , University of South Florida
Inventor: Sanket Jaiprakash Mishra , Brian S. J. Blagg , Chad Anthony Dickey
IPC: C07D207/325 , A61P27/06 , A61P35/00 , C07C13/18 , C07D213/62 , C07D401/06
CPC classification number: C07D207/325 , A61P27/06 , A61P35/00 , C07C13/18 , C07D213/62 , C07D401/06
Abstract: The present technology provides compounds according to Formula I or Formula III as well as compositions including such compounds useful for the treatment of metastatic cancer and/or glaucoma.
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公开(公告)号:US20240067600A1
公开(公告)日:2024-02-29
申请号:US18122605
申请日:2023-03-16
Applicant: UNIVERSITY OF KANSAS , Oregon Health & Science University
Inventor: Sudeshna ROY , Paolo BERNARDI , Michael FORTE , Frank SCHOENEN , Justina SILEIKYTE
IPC: C07C235/42 , A61K31/415 , A61K31/42 , A61P21/00 , A61P25/00 , C07C235/38 , C07C235/56 , C07D203/04 , C07D211/14 , C07D231/14 , C07D261/18 , C07D295/135 , C07D295/185 , C07D413/12
CPC classification number: C07C235/42 , A61K31/415 , A61K31/42 , A61P21/00 , A61P25/00 , C07C235/38 , C07C235/56 , C07D203/04 , C07D211/14 , C07D231/14 , C07D261/18 , C07D295/135 , C07D295/185 , C07D413/12
Abstract: The present technology relates to compounds of any one of Formula I, II, IIa, III, IV, and/or V as described herein and their tautomers and/or pharmaceutically acceptable salts, compositions, and methods of uses thereof.
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公开(公告)号:US11911626B2
公开(公告)日:2024-02-27
申请号:US17212370
申请日:2021-03-25
Applicant: UNIVERSITY OF KANSAS
Inventor: Elizabeth Annamaria Friis , John Patrick Domann , Paul M. Arnold
IPC: A61N1/378 , H02N2/18 , H10N30/02 , H10N30/30 , H10N30/50 , H10N30/057 , H10N30/88 , H10N30/092 , H10N30/80 , H10N30/85 , H10N30/87 , A61F2/44 , A61N1/20 , A61N1/05 , A61N1/32 , A61F2/28
CPC classification number: A61N1/378 , A61F2/4455 , A61N1/20 , A61N1/3785 , H02N2/181 , H10N30/02 , H10N30/057 , H10N30/092 , H10N30/30 , H10N30/50 , H10N30/505 , H10N30/506 , H10N30/802 , H10N30/852 , H10N30/875 , H10N30/88 , A61F2002/2821 , A61N1/056 , A61N1/0529 , A61N1/0551 , A61N1/205 , A61N1/326
Abstract: The present application relates to stacked piezoelectric composites comprising piezoelectric structures. Suitably, the composites are useful as tissue-stimulating implants, including spinal fusion implants. The present application also relates to methods of making stacked piezoelectric composites.
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