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公开(公告)号：US10737224B2
公开(公告)日：2020-08-11
申请号：US15575596
申请日：2016-08-12
Applicant: EMD Millipore Corporation
Inventor： Jad Jaber , Wilson Moya , Mikhail Kozlov
Abstract: The embodiments described herein relate to agarose ultrafiltration membrane composites and methods for making and using the same.
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公开(公告)号：US20150060342A1
公开(公告)日：2015-03-05
申请号：US14535461
申请日：2014-11-07
Applicant: EMD Millipore Corporation
Inventor： Anthony J. DiLeo , Justin McCue , Wilson Moya , Igor Quinones-Garcia , Neil P. Soice , Volkmar Thom , Sarah Yuan
CPC classification number: B01D15/20 , B01D15/265 , B01D15/361 , B01J20/26 , B01J20/28023 , B01J20/28033 , B01J20/28042 , B01J20/28078 , B01J20/28097 , B01J20/286 , B01J20/3064 , B01J20/321 , B01J20/3212 , B01J20/327 , B01J20/3272 , B01J20/3274 , B01J20/328 , B01J20/3282 , B01J20/3289 , B01J20/3293 , B01J2220/54 , B01J2220/58 , B01J2220/62
Abstract: A porous substrate capable of adsorptive filtration of a fluid having a porous self-supporting substrate and one or more porous, adsorptive polymeric coatings comprising from about 1 to about 80% of the void volume of the pores of the substrate. The resultant substrate has good convective and diffusive flow and capacity. The substrate may be cross-linked, have one or more capture chemistries attached to it and is useful as a chromatography media for the selective filtration of desired species including biomolecules such as proteins and DNA fragments.
Abstract translation: 能够吸附过滤具有多孔自支撑基底和一种或多种多孔吸附聚合物涂层的多孔基底，其包含基底孔隙体积的约1至约80％。 所得到的底物具有良好的对流和扩散流量和容量。 底物可以是交联的，具有一个或多个捕获化学物质连接到其上，并且可用作用于选择性过滤所需物质（包括生物分子例如蛋白质和DNA片段）的色谱介质。
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公开(公告)号：US20220323300A1
公开(公告)日：2022-10-13
申请号：US17639973
申请日：2020-09-09
Applicant: James DEE , George GAGNE , Daniel LAMOTHE , EMD Millipore Corporation
Inventor： Shannon Cleveland , Marina Varlamova , John Saragosa , David DeCoste , Benjamin Cacace , Daniel Lamothe , George Gagne , James Dee , Wilson Moya , Stefano Berti Perez
Abstract: A biocontainer having a first film, the film having an interior and exterior side; articulating elements disposed on or within the first film, the articulating elements comprising at least one a folded hinge, a sealed joint, a thinned pathway, a bowed path, an embedded polymeric or metallic cylindrical fiber or rod; and a second film, optionally comprising articulating elements, joined to the first film, to form a biocontainer having a closed volume, wherein the articulating elements permit the biocontainer to expand and collapse along the articulating elements.
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公开(公告)号：US11358102B2
公开(公告)日：2022-06-14
申请号：US16918431
申请日：2020-07-01
Applicant: EMD Millipore Corporation
Inventor： Jad Jaber , Wilson Moya , Mikhail Kozlov
Abstract: The embodiments described herein relate to agarose ultrafiltration membrane composites and methods for making and using the same.
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公开(公告)号：US20200368696A1
公开(公告)日：2020-11-26
申请号：US16918431
申请日：2020-07-01
Applicant: EMD Millipore Corporation
Inventor： Jad Jaber , Wilson Moya , Mikhail Kozlov
Abstract: The embodiments described herein relate to agarose ultrafiltration membrane composites and methods for making and using the same.
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Patent Agency Ranking
公开(公告)号：US10252199B2
公开(公告)日：2019-04-09
申请号：US15448248
申请日：2017-03-02
Applicant: EMD Millipore Corporation
Inventor： Onur Y. Kas , Mikhail Kozlov , Wilson Moya , Sherry A. Leon , Philip Goddard , Jibin Hao , Gabriel Tkacik
IPC: B01D39/16 , B01D39/18 , B01D39/14 , A61L2/02 , C12N7/00 , D01D1/02 , D01D5/00 , D01F6/96 , B01D69/02 , B01D69/10 , B01D39/04 , B01D39/00 , B01D67/00 , B01D61/14
Abstract: A method for removing retroviruses from liquid samples and a nanofiber containing liquid filtration medium that simultaneously exhibits high liquid permeability and high microorganism retention is disclosed. Retroviruses are removed from a liquid by passing the liquid through a porous nanofiber containing filtration medium having a retrovirus LRV greater than about 6, and the nanofiber(s) has a diameter from about 10 nm to about 100 nm. The filtration medium can be in the form of a fibrous electrospun polymeric nanofiber liquid filtration medium mat.
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公开(公告)号：US20170360971A1
公开(公告)日：2017-12-21
申请号：US15691369
申请日：2017-08-30
Applicant: EMD Millipore Corporation
Inventor： Mikhail Kozlov , Wilson Moya , Gabriel Tkacik
CPC classification number: A61L2/0017 , B01D39/1623 , B01D67/0004 , B01D67/002 , B01D69/00 , B01D2239/025 , B01D2323/39 , C02F1/444 , C02F2303/04
Abstract: A method for removing microorganisms from liquid samples and a nanofiber containing liquid filtration medium that simultaneously exhibits high liquid permeability and high microorganism retention. Microorganisms such as bacteria, particularly B. Diminuta, are removed from a liquid by passing the liquid through a porous nanofiber containing filtration medium having a B. Diminuta LRV greater than about 9, and the nanofiber(s) has a diameter from about 10 nm to about 1,000 nm. Another method for removing microorganisms such as bacteria and Mycloplasma, includes passing the liquid through a porous nanofiber containing filtration medium having a microorganism LRV greater than about 8, and the nanofiber(s) has a diameter from about 10 nm to about 1,000 nm. The filtration medium can be in the form of a fibrous electro spun polymeric nanofiber liquid filtration medium mat.
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公开(公告)号：US20170173511A1
公开(公告)日：2017-06-22
申请号：US15448248
申请日：2017-03-02
Applicant: EMD Millipore Corporation
Inventor： Onur Y. Kas , Mikhail Kozlov , Wilson Moya , Sherry A. Leon , Philip Goddard , Jibin Hao , Gabriel Tkacik
CPC classification number: B01D39/1607 , A61L2/022 , B01D39/00 , B01D39/04 , B01D39/14 , B01D39/16 , B01D39/1615 , B01D39/1623 , B01D39/18 , B01D61/14 , B01D67/0004 , B01D67/002 , B01D69/02 , B01D69/10 , B01D2239/0208 , B01D2239/0216 , B01D2239/025 , B01D2239/0442 , B01D2239/0631 , B01D2239/10 , B01D2239/1233 , B01D2323/39 , B01D2323/42 , B01D2325/20 , C12N7/00 , C12N2740/16051 , D01D1/02 , D01D5/0092 , D01F6/96 , D10B2505/04
Abstract: A method for removing retroviruses from liquid samples and a nanofiber containing liquid filtration medium that simultaneously exhibits high liquid permeability and high microorganism retention is disclosed. Retroviruses are removed from a liquid by passing the liquid through a porous nanofiber containing filtration medium having a retrovirus LRV greater than about 6, and the nanofiber(s) has a diameter from about 10 nm to about 100 nm. The filtration medium can be in the form of a fibrous electrospun polymeric nanofiber liquid filtration medium mat.
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公开(公告)号：US09376464B2
公开(公告)日：2016-06-28
申请号：US13747495
申请日：2013-01-23
Applicant: EMD Millipore Corporation
Inventor： Wilson Moya , Jad Jaber
Abstract: The present invention relates to a selectively soluble polymer capable of binding to a desired biomolecules in a mixture containing various biological materials and the methods of using such a polymer to purify a biomolecule from such a mixture. The polymer is soluble in the mixture under a certain set of process conditions such as pH or temperature and/or salt concentration and is rendered insoluble and precipitates out of solution upon a change in the process conditions. The polymer is capable of binding to the desired biomolecule (protein, polypeptide, etc) and remains capable of binding to that biomolecule even after the polymer is precipitated out of solution. The precipitate can then be filtered out from the remainder of the stream and the desired biomolecule is recovered such as by elution and further processed.
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公开(公告)号：US09217048B2
公开(公告)日：2015-12-22
申请号：US14183791
申请日：2014-02-19
Applicant: EMD Millipore Corporation
Inventor： Jad Jaber , Wilson Moya , James Hamzik , Arezki Boudif , Yu Zhang , Neil Soice , John Charkoudian , Nripen Singh
IPC: C08F126/00 , C08F126/02 , C07K1/30 , C07K1/32 , C08F8/00 , C08F8/02 , C07K16/00
CPC classification number: B01J41/14 , B01J41/13 , C07K1/30 , C07K1/32 , C07K16/00 , C07K2317/10 , C08F8/00 , C08F8/02 , C08F126/02 , C08F26/02
Abstract: The present invention provides novel and improved stimulus responsive polymers and methods of using the same for the purification of biomolecules.
Abstract translation: 本发明提供了新的和改进的刺激响应聚合物及其用于生物分子纯化的方法。
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