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公开(公告)号：US20090294144A1
公开(公告)日：2009-12-03
申请号：US12539816
申请日：2009-08-12
Applicant: Karl Frauhammer , Gerhard Meixner , Heiko Roehm , Willy Braun , Axel Kuhnle , Andreas Strasser , Ralph Dammertz , Joachim Schadow , Christian Koepf , Juergen Lennartz
Inventor： Karl Frauhammer , Gerhard Meixner , Heiko Roehm , Willy Braun , Axel Kuhnle , Andreas Strasser , Ralph Dammertz , Joachim Schadow , Christian Koepf , Juergen Lennartz
CPC classification number: B25D17/043
Abstract: A hand-held power tool has a main element; a main handle fastened to the main element, the main handle being supported such that the main handle is movable relative to the main element, the main element including a tool fitting that defines a tool axis and the center of gravity that defines a normal direction oriented perpendicular to the tool axis and pointing toward the center of gravity, the main element being moved out of a stationary position toward the main handle so that a portion of at least 10% by weight of the main element is guided with a movement component in the normal direction along a trajectory.
Abstract translation: 手持式电动工具具有主要元件; 主把手被固定到主元件，主把手被支撑为使得主手柄相对于主元件可移动，主元件包括限定工具轴线的工具配件和限定法线方向取向的重心 垂直于工具轴线并指向重心，主元件从静止位置移动到主把手，使得主元件的至少10重量％的部分被引导到主元件的移动部件 正常方向沿轨迹。
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公开(公告)号：US20060185867A1
公开(公告)日：2006-08-24
申请号：US11326046
申请日：2006-01-05
Applicant: Karl Frauhammer , Gerhard Meixner , Heiko Roehm , Willy Braun , Axel Kuhnle , Andreas Strasser , Ralph Dammertz , Joachim Schadow , Christian Koepf , Juergen Lennartz
Inventor： Karl Frauhammer , Gerhard Meixner , Heiko Roehm , Willy Braun , Axel Kuhnle , Andreas Strasser , Ralph Dammertz , Joachim Schadow , Christian Koepf , Juergen Lennartz
IPC: E21B19/16
CPC classification number: B25D17/043
Abstract: A hand-held power tool has a main element; a main handle fastened to the main element, the main handle being supported such that the main handle is movable relative to the main element, the main element including a tool fitting that defines a tool axis and the center of gravity that defines a normal direction oriented perpendicular to the tool axis and pointing toward the center of gravity, the main element being moved out of a stationary position toward the main handle so that a portion of at least 10% by weight of the main element is guided with a movement component in the normal direction along a trajectory.
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公开(公告)号：US20050161241A1
公开(公告)日：2005-07-28
申请号：US11019428
申请日：2004-12-22
Applicant: Karl Frauhammer , Gerhard Meixner , Axel Kuhnle , Andreas Strasser , Erhard Hoffmann , Dietmar Hahn , Andreas Heilmann , Ulrich Single
Inventor： Karl Frauhammer , Gerhard Meixner , Axel Kuhnle , Andreas Strasser , Erhard Hoffmann , Dietmar Hahn , Andreas Heilmann , Ulrich Single
Abstract: The invention relates to a handle for an electric tool. The handle according to the invention has at least one detecting unit.
Abstract translation: 本发明涉及一种电动工具的手柄。 根据本发明的手柄具有至少一个检测单元。
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公开(公告)号：US20130172177A1
公开(公告)日：2013-07-04
申请号：US13824113
申请日：2011-09-13
Applicant: Imme Domke , Wolfgang Rohde , Piotr Antoni Bazula , Norbert Mronga , Yong Liu , Martin Dieterle , Stanley Roth , Curtis Zimmermann , Xinyi Wei , Philipp Raff , Stephan Andreas Schunk , Olga Gerlach , Andreas Strasser , Michael Paul
Inventor： Imme Domke , Wolfgang Rohde , Piotr Antoni Bazula , Norbert Mronga , Yong Liu , Martin Dieterle , Stanley Roth , Curtis Zimmermann , Xinyi Wei , Philipp Raff , Stephan Andreas Schunk , Olga Gerlach , Andreas Strasser , Michael Paul
IPC: B01J23/42
CPC classification number: B01J23/42 , B01D53/945 , B01D2255/1021 , B01D2255/1023 , B01D2255/1025 , B01D2255/1026 , B01D2255/104 , B01D2255/2065 , B01D2255/20707 , B01D2255/20715 , B01D2255/20723 , B01D2255/2073 , B01D2255/20738 , B01D2255/20746 , B01D2255/20753 , B01D2255/20761 , B01D2255/20769 , B01D2255/20784 , B01D2255/20792 , B01D2255/9202 , B01D2255/9205 , B01D2255/9207 , B01D2258/012 , B01J21/04 , B01J21/08 , B01J35/0013 , B01J35/0086 , B01J35/08 , B01J35/1014 , B01J35/1019 , B01J37/0072 , B01J37/0203 , B01J37/0205 , B01J37/0211 , B01J37/036 , B01J37/088 , B01J37/16 , Y02T10/22
Abstract: A catalyst comprising (i) a support, (ii) metal particles and (iii) a shell which is arranged between the metal particles, wherein the shell (iii) comprises silicon oxide.
Abstract translation: 一种催化剂，其包含（i）载体，（ii）金属颗粒和（iii）布置在金属颗粒之间的壳，其中壳（iii）包含氧化硅。
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公开(公告)号：US20110052603A1
公开(公告)日：2011-03-03
申请号：US12444579
申请日：2007-10-05
Applicant: Philippe Bouillet , Andreas Strasser , Steve Gerondakis , Fook Lin Tai , Thomas Kaufmann , Raffi Gugasyan
Inventor： Philippe Bouillet , Andreas Strasser , Steve Gerondakis , Fook Lin Tai , Thomas Kaufmann , Raffi Gugasyan
IPC: A61K39/395 , C12N5/00 , A61K31/7088 , A61K38/02 , A61K38/45 , A61K38/46 , A61K38/48 , A61P37/06 , A61P31/12 , A61P1/16 , A61P35/00
CPC classification number: A61K38/45 , A61K38/482 , A61K38/4873
Abstract: The present invention relates generally to a method of modulating tumor necrosis factor-mediated apoptosis and to agents useful for same. More particularly, the present invention contemplates a method of modulating tumor necrosis factor-mediated hepatocyte apoptosis by modulating an intracellular Bim and/or Bid-dependent signalling mechanism. The method of the present invention is useful, inter alia, in the treatment and/or prophylaxis of conditions characterized by aberrant, unwanted or otherwise inappropriate tumor necrosis factor-mediated apoptosis. The present invention is further directed to methods for identifying and/or designing agents capable of modulating the subject Bim and/or Bid-dependent signalling mechanism.
Abstract translation: 本发明一般涉及调节肿瘤坏死因子介导的细胞凋亡的方法以及可用于其的药剂。 更具体地，本发明考虑通过调节细胞内Bim和/或Bid依赖性信号传导机制来调节肿瘤坏死因子介导的肝细胞凋亡的方法。 本发明的方法尤其可用于治疗和/或预防以异常，不想要或其他不适当的肿瘤坏死因子介导的细胞凋亡为特征的病症。 本发明还涉及用于鉴定和/或设计能够调节受试者Bim和/或Bid依赖性信号传导机制的试剂的方法。
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Patent Agency Ranking
16.发明授权Method of processing a contact pad, method of manufacturing a contact pad, and integrated circuit element 有权接触垫的处理方法，接触垫的制造方法以及集成电路元件公开(公告)号：US07829450B2
公开(公告)日：2010-11-09
申请号：US11936541
申请日：2007-11-07
Applicant: Markus Hammer , Guenther Ruhl , Andreas Strasser , Michael Melzl , Reinhard Goellner , Doerthe Groteloh
Inventor： Markus Hammer , Guenther Ruhl , Andreas Strasser , Michael Melzl , Reinhard Goellner , Doerthe Groteloh
IPC: H01L21/44
CPC classification number: H01L23/3192 , H01L24/03 , H01L24/05 , H01L2224/05006 , H01L2224/05082 , H01L2224/05184 , H01L2224/05571 , H01L2224/05624 , H01L2224/05647 , H01L2924/0002 , H01L2924/01005 , H01L2924/01006 , H01L2924/01007 , H01L2924/01013 , H01L2924/01014 , H01L2924/01015 , H01L2924/01018 , H01L2924/01027 , H01L2924/01028 , H01L2924/01029 , H01L2924/01032 , H01L2924/01046 , H01L2924/01047 , H01L2924/01068 , H01L2924/01074 , H01L2924/01075 , H01L2924/01078 , H01L2924/01079 , H01L2924/01082 , H01L2924/05042 , H01L2924/14 , Y10S438/954 , Y10S438/958 , H01L2924/00014 , H01L2224/05552
Abstract: In a method of processing a contact pad, a passivation layer stack including at least one passivation layer is formed on at least an upper surface of a contact pad region. A first portion of the passivation layer stack is removed from above the contact pad region, wherein a second portion of the passivation layer remains on the contact pad region and covers the contact pad region. An adhesion layer is formed on the passivation layer stack. The adhesion layer is patterned, wherein the adhesion layer is removed from above the contact pad region. Furthermore, the second portion of the passivation layer stack is removed.
Abstract translation: 在处理接触焊盘的方法中，在接触焊盘区域的至少上表面上形成包括至少一个钝化层的钝化层堆叠。 钝化层堆叠的第一部分从接触焊盘区域上方去除，其中钝化层的第二部分保留在接触焊盘区域上并覆盖接触焊盘区域。 在钝化层堆叠上形成粘附层。 图案化附着层，其中从接触焊盘区域上方去除粘附层。 此外，去除钝化层堆叠的第二部分。
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17.发明申请Method of Processing a Contact Pad, Method of Manufacturing a Contact Pad, and Integrated Circuit Element 有权接触垫的加工方法，接触垫的制造方法以及集成电路元件公开(公告)号：US20090115074A1
公开(公告)日：2009-05-07
申请号：US11936541
申请日：2007-11-07
Applicant: Markus Hammer , Guenther Ruhl , Andreas Strasser , Michael Melzl , Reinhard Goellner , Doerthe Groteloh
Inventor： Markus Hammer , Guenther Ruhl , Andreas Strasser , Michael Melzl , Reinhard Goellner , Doerthe Groteloh
IPC: H01L21/441 , H01L23/52
CPC classification number: H01L23/3192 , H01L24/03 , H01L24/05 , H01L2224/05006 , H01L2224/05082 , H01L2224/05184 , H01L2224/05571 , H01L2224/05624 , H01L2224/05647 , H01L2924/0002 , H01L2924/01005 , H01L2924/01006 , H01L2924/01007 , H01L2924/01013 , H01L2924/01014 , H01L2924/01015 , H01L2924/01018 , H01L2924/01027 , H01L2924/01028 , H01L2924/01029 , H01L2924/01032 , H01L2924/01046 , H01L2924/01047 , H01L2924/01068 , H01L2924/01074 , H01L2924/01075 , H01L2924/01078 , H01L2924/01079 , H01L2924/01082 , H01L2924/05042 , H01L2924/14 , Y10S438/954 , Y10S438/958 , H01L2924/00014 , H01L2224/05552
Abstract: In a method of processing a contact pad, a passivation layer stack including at least one passivation layer is formed on at least an upper surface of a contact pad region. A first portion of the passivation layer stack is removed from above the contact pad region, wherein a second portion of the passivation layer remains on the contact pad region and covers the contact pad region. An adhesion layer is formed on the passivation layer stack. The adhesion layer is patterned, wherein the adhesion layer is removed from above the contact pad region. Furthermore, the second portion of the passivation layer stack is removed.
Abstract translation: 在处理接触焊盘的方法中，在接触焊盘区域的至少上表面上形成包括至少一个钝化层的钝化层堆叠。 钝化层堆叠的第一部分从接触焊盘区域上方去除，其中钝化层的第二部分保留在接触焊盘区域上并覆盖接触焊盘区域。 在钝化层堆叠上形成粘附层。 图案化附着层，其中从接触焊盘区域上方去除粘附层。 此外，去除钝化层堆叠的第二部分。
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公开(公告)号：US07064193B1
公开(公告)日：2006-06-20
申请号：US09508832
申请日：1998-09-17
Applicant: Suzanne Cory , Jerry Adams , David C. S. Huang , Liam O'Connor , Andreas Strasser , Hamsa Puthalakath , Lorraine O'Reilly
Inventor： Suzanne Cory , Jerry Adams , David C. S. Huang , Liam O'Connor , Andreas Strasser , Hamsa Puthalakath , Lorraine O'Reilly
CPC classification number: C07K14/4747 , A61K38/00
Abstract: The present invention relates generally to novel molecules capable of, inter alia, modulating apoptosis in mammalian cells and to genetic sequences encoding same. More particularly, the present invention relates to a novel member of the Bcl-2 family of proteins, referred to herein as “Bim”, and to genetic sequences encoding same. The molecules of the present invention are useful, for example, in therapy, diagnosis, antibody generation and as a screening tool for therapeutic agents capable of modulating physiological cell death or survival and/or modulating cell cycle entry.
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19.发明申请Bcl-2-modifying factor (bmf) sequences and their use in modulating apoptosis 失效Bcl-2修饰因子（bmf）序列及其在凋亡调控中的应用公开(公告)号：US20050064593A1
公开(公告)日：2005-03-24
申请号：US10479307
申请日：2002-05-30
Applicant: Andreas Strasser , Hamsa Puthalakath , Andreas Villunger , Leigh Coultas , Jennifer Beaumont , Lorraine O'reilly , David Huang
Inventor： Andreas Strasser , Hamsa Puthalakath , Andreas Villunger , Leigh Coultas , Jennifer Beaumont , Lorraine O'reilly , David Huang
IPC: A01K67/027 , A61K38/00 , A61K45/00 , A61P31/12 , A61P35/00 , A61P37/00 , A61P43/00 , C07K14/47 , C07K16/18 , C12N5/10 , C12N15/09 , C12N15/11 , C12N15/12 , C12P21/08 , G01N33/53 , A61K48/00 , C07H21/04
CPC classification number: C07K14/4747 , A01K2217/05 , A61K38/00
Abstract: The present invention relates generally to novel molecules capable of, inter alia, modulating apoptosis in mammalian cells and to genetic sequences encoding same. More particularly, the present invention relates to a novel member of the Bcl-2 family of proteins, referred to herein as “Bmf”, and to genetic sequences encoding same and to regulatory sequences such as a promoter sequence directing expression of Bmf. Bmf comprises a BH3 domain which facilitates interaction to pro-survival Bcl-2 family members thereby triggering apoptosis. Bmf is regarded, therefore, as a BH3-only molecule. The molecules of the present invention are useful, for example, in therapy, diagnosis, antibody generation and as a screening tool for therapeutic agents capable of modulating physiological cell death or survival and/or modulating cell cycle entry. The present invention further contemplates genetically modified animals in which one or both alleles of Bmf are mutated or partially or wholly deleted alone or in combination with a mutation in one or both alleles of another Bcl-2-type molecule such as but not limited to Bim. The genetically modified animals are useful inter alia in screening for agents which ameliorate the symptoms of diseases caused by defects in apoptosis or which specifically promote apoptosis of target cells.
Abstract translation: 本发明一般涉及能够特别调节哺乳动物细胞凋亡和编码其的遗传序列的新型分子。 更具体地，本发明涉及Bcl-2家族蛋白质的新成员，本文称为“Bmf”，以及编码它们的遗传序列以及调节序列，例如引导Bmf表达的启动子序列。 Bmf包含BH3结构域，其促进与生存Bcl-2家族成员的相互作用，从而引发细胞凋亡。 因此，Bmf被认为是仅BH3分子。 本发明的分子可用于例如治疗，诊断，抗体产生以及作为能够调节生理细胞死亡或生存和/或调节细胞周期进入的治疗剂的筛选工具。 本发明进一步考虑了遗传修饰的动物，其中Bmf的一个或两个等位基因单独突变或部分或全部缺失，或与另一个Bcl-2型分子的一个或两个等位基因中的突变组合，例如但不限于Bim 。 遗传修饰的动物尤其可用于筛选改善由凋亡缺陷引起的疾病症状或特异性促进靶细胞凋亡的药剂。
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公开(公告)号：US20130065075A1
公开(公告)日：2013-03-14
申请号：US13230123
申请日：2011-09-12
Applicant: Klemens Pruegl , Juergen Zimmer , Andreas Strasser , Wolfgang Raberg , Thomas Bever
Inventor： Klemens Pruegl , Juergen Zimmer , Andreas Strasser , Wolfgang Raberg , Thomas Bever
CPC classification number: H01L43/08 , G01R33/098 , H01L43/12 , Y10T428/12465 , Y10T428/265 , Y10T428/31678
Abstract: Embodiments relate to magnetoresistive (MR) sensors, sensor elements and structures, and methods. In particular, embodiments relate to MR, such as giant MR (GMR) or tunneling MR (TMR), spin valve layer systems and related sensors having improved stability. Embodiments include at least one of a multi-layer pinned layer or a multi-layer reference layer, making the stack more stable and therefore suitable for use at higher temperatures and magnetic fields than conventional systems and sensors.
Abstract translation: 实施例涉及磁阻（MR）传感器，传感器元件和结构以及方法。 特别地，实施例涉及MR，例如巨磁（GMR）或隧道MR（TMR），自旋阀层系统和具有改进的稳定性的相关传感器。 实施例包括多层被钉扎层或多层参考层中的至少一个，使得堆叠更加稳定，因此适合于在比常规系统和传感器更高的温度和磁场下使用。
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