-
公开(公告)号：US20180361381A1
公开(公告)日：2018-12-20
申请号：US16058828
申请日：2018-08-08
Applicant: IMEC VZW
Inventor： Peter Peumans , Liesbet Lagae , Paolo Fiorini
Abstract: The present disclosure relates to a fluid analyzing device that includes a sensing device for analyzing a fluid sample. The sensing device includes a microchip configured for sensing the fluid sample, and a closed micro-fluidic component for propagating the fluid sample to the microchip. The fluid sample can be provided to the micro-fluidic component via an inlet of the fluid analyzing device. And a vacuum compartment, which is air-tight connected to the sensing device, can create in the micro-fluidic component a suction force suitable for propagating the fluid sample through the micro-fluidic component.
-
公开(公告)号：US10100352B2
公开(公告)日：2018-10-16
申请号：US14196293
申请日：2014-03-04
Applicant: Panasonic Corporation , IMEC vzw
Inventor： Hiroyuki Tanaka , Maki Hiraoka , Benjamin Jones , Paolo Fiorini
Abstract: Provided is a DNA chip with micro-channel for DNA analysis, which has a structure in which a silicon layer (chip A) and a plastic layer (chip B) are laminated, wherein the chip A includes at least two PCR reactors connected in series in a micro-channel, and a filter between the PCR reactors, the chip B includes a reagent, a liquid delivery mechanism and a sensor in a micro-channel, and the reagent, liquid delivery mechanism and sensor can be changed according to a kind of an analyte and an object to be detected.
-
公开(公告)号：US11752498B2
公开(公告)日：2023-09-12
申请号：US17475807
申请日：2021-09-15
Applicant: Imec vzw
Inventor： Benjamin Jones , Tim Stakenborg , Paolo Fiorini
CPC classification number: B01L3/502707 , B01L3/50273 , B01L3/502715 , B01L3/502738 , F16K99/0021 , B01J2219/00353 , B01J2219/00389 , B01J2219/00414 , B01J2219/00418 , B01J2219/00637 , B01L3/502746 , B01L2200/0689 , B01L2300/0636 , B01L2300/0816 , B01L2300/0864 , B01L2300/0867 , B01L2300/16 , B01L2400/0406 , B01L2400/0487 , B01L2400/0688 , B01L2400/086 , B05C7/04
Abstract: A fluidic device (100) is described for locally coating an inner surface of a fluidic channel. The fluidic device (100) comprises a first (101), a second (102) and a third (103) fluidic channel intersecting at a common junction (105). The first fluidic channel is connectable to a coating fluid reservoir and the third fluidic channel is connectable to a sample fluid reservoir. The fluidic device (100) further comprises a fluid control means (111) configured for creating a fluidic flow path for a coating fluid at the common junction (105) such that, when coating, a coating fluid propagates from the first (101) to the second (102) fluidic channel via the common junction (105) without propagating into the third (103) fluidic channel. A corresponding method for coating and for sensing also has been disclosed.
-
公开(公告)号：US20190351415A1
公开(公告)日：2019-11-21
申请号：US16410622
申请日：2019-05-13
Applicant: IMEC VZW , Katholieke Universiteit Leuven, KU LEUVEN R&D
Inventor： Ujjal Barman , Benjamin Jones , Paolo Fiorini , David Mikaelian
Abstract: A microfluidic device for electrically activating a passive capillary stop valve, an apparatus and method are provided. The microfluidic device includes a first channel for containing a first fluid, and an output channel, wherein the first channel comprises a first interface with the output channel, and the first interface comprises a capillary stop valve characterised in that the microfluidic device also comprises a second channel for containing a second fluid, wherein the second channel comprises a second interface with the output channel, and the first channel and the second channel are electrically isolated from each other, and the first interface and the second interface are arranged relative to each other thereby being configured to activate fluid flow from the first channel into the output channel when a first fluid and a second fluid are present, and an electrical potential difference is applied between the first fluid and the second fluid.
-
公开(公告)号：US20180345287A1
公开(公告)日：2018-12-06
申请号：US16059576
申请日：2018-08-09
Applicant: IMEC VZW
Inventor： Paolo Fiorini , Tim Stakenborg , Frederik Colle
CPC classification number: B01L3/502784 , B01L7/52 , B01L2200/061 , B01L2200/0673 , B01L2200/10 , B01L2300/0627 , B01L2300/0816 , B01L2300/0867 , B01L2300/0883 , B01L2300/1827 , C12Q1/686
Abstract: A micro-fluidic device 100 for performing digital PCR is presented. The device comprises: a semiconductor substrate; a first micro-fluidic channel 104, comprising an inlet 102 and an outlet 103, embedded in the semiconductor substrate; a heating element 101 thermally coupled to the first micro-fluidic channel 104; a droplet generator 107 connected to the inlet 102 of the first micro-fluidic channel 104 for generating droplets and pumping generated droplets at a flow rate into the first micro-fluidic channel 104; characterized in that: the heating element 101 is a single heating element connected to a temperature control unit 111 configured to cycle the temperature of the complete first micro-fluidic channel 104 through at least two temperature values; and wherein the flow rate of the droplet generator 107 is adaptable. Further, a method to perform digital PCR is presented using the micro-fluidic device 100.
-
Patent Agency Ranking
公开(公告)号：US20170326551A1
公开(公告)日：2017-11-16
申请号：US15529424
申请日：2015-11-24
Applicant: IMEC VZW
Inventor： Peter Peumans , Liesbet Lagae , Paolo Fiorini
CPC classification number: B01L3/502715 , B01L3/5027 , B01L3/502707 , B01L3/50273 , B01L2200/027 , B01L2200/10 , B01L2300/041 , B01L2300/044 , B01L2300/046 , B01L2300/0627 , B01L2300/0645 , B01L2300/0672 , B01L2300/0816 , B01L2300/0825 , B01L2300/0848 , B01L2300/0867 , B01L2300/087 , B01L2300/0883 , B01L2300/0887 , B01L2300/1827 , B01L2400/0406 , B01L2400/049 , B01L2400/0683 , B01L2400/086 , G01N1/14 , G01N1/38 , G01N33/49 , G01N2001/386
Abstract: The present disclosure relates to a fluid analysis device which comprises a sensing device for analyzing a fluid sample, the sensing device comprising a micro-fluidic component for propagating the fluid sample and a microchip configured for sensing the fluid sample in the micro-fluidic component; a sealed fluid compartment containing a further fluid, the compartment being fluid-tight connected to the sensing device and adapted for providing the further fluid to the micro-fluidic component when the sealed fluid compartment is opened; and an inlet for providing the fluid sample to the micro-fluidic component. Further, the present disclosure relates to a method for sensing a fluid sample using the fluid analysis device.
-
公开(公告)号：US11266990B2
公开(公告)日：2022-03-08
申请号：US16059576
申请日：2018-08-09
Applicant: IMEC VZW
Inventor： Paolo Fiorini , Tim Stakenborg , Frederik Colle
Abstract: A micro-fluidic device 100 for performing digital PCR is presented. The device comprises: a semiconductor substrate; a first micro-fluidic channel 104, comprising an inlet 102 and an outlet 103, embedded in the semiconductor substrate; a heating element 101 thermally coupled to the first micro-fluidic channel 104; a droplet generator 107 connected to the inlet 102 of the first micro-fluidic channel 104 for generating droplets and pumping generated droplets at a flow rate into the first micro-fluidic channel 104; characterized in that: the heating element 101 is a single heating element connected to a temperature control unit 111 configured to cycle the temperature of the complete first micro-fluidic channel 104 through at least two temperature values; and wherein the flow rate of the droplet generator 107 is adaptable. Further, a method to perform digital PCR is presented using the micro-fluidic device 100.
-
公开(公告)号：US11130124B2
公开(公告)日：2021-09-28
申请号：US15737013
申请日：2016-06-20
Applicant: IMEC VZW
Inventor： Benjamin Jones , Tim Stakenborg , Paolo Fiorini
Abstract: A fluidic device is described for locally coating an inner surface of a fluidic channel. The fluidic device comprises a first, a second and a third fluidic channel intersecting at a common junction. The first fluidic channel is connectable to a coating fluid reservoir and the third fluidic channel is connectable to a sample fluid reservoir. The fluidic device further comprises a fluid control means configured for creating a fluidic flow path for a coating fluid at the common junction such that, when coating, a coating fluid propagates from the first to the second fluidic channel via the common junction without propagating into the third fluidic channel. A corresponding method for coating and for sensing also has been disclosed.
-
公开(公告)号：US20180169652A1
公开(公告)日：2018-06-21
申请号：US15737013
申请日：2016-06-20
Applicant: IMEC VZW
Inventor： Benjamin Jones , Tim Stakenborg , Paolo Fiorini
IPC: B01L3/00
CPC classification number: B01L3/502707 , B01J2219/00353 , B01J2219/00389 , B01J2219/00414 , B01J2219/00418 , B01J2219/00637 , B01L3/502715 , B01L3/50273 , B01L3/502738 , B01L3/502746 , B01L2200/0689 , B01L2300/0636 , B01L2300/0816 , B01L2300/0864 , B01L2300/0867 , B01L2300/16 , B01L2400/0406 , B01L2400/0487 , B01L2400/0688 , B01L2400/086 , B05C7/04 , F16K99/0021
Abstract: A fluidic device is described for locally coating an inner surface of a fluidic channel. The fluidic device comprises a first, a second and a third fluidic channel intersecting at a common junction. The first fluidic channel is connectable to a coating fluid reservoir and the third fluidic channel is connectable to a sample fluid reservoir. The fluidic device further comprises a fluid control means configured for creating a fluidic flow path for a coating fluid at the common junction such that, when coating, a coating fluid propagates from the first to the second fluidic channel via the common junction without propagating into the third fluidic channel. A corresponding method for coating and for sensing also has been disclosed.
-
公开(公告)号：US20170326552A1
公开(公告)日：2017-11-16
申请号：US15529441
申请日：2015-11-24
Applicant: IMEC VZW
Inventor： Peter Peumans , Liesbet Lagae , Paolo Fiorini
CPC classification number: B01L3/502715 , A61B5/150022 , A61B5/150061 , A61B5/150389 , A61B5/151 , A61B5/157 , A61B2562/028 , B01L3/5027 , B01L3/50273 , B01L2200/10 , B01L2300/041 , B01L2300/046 , B01L2300/0654 , B01L2300/0672 , B01L2300/0816 , B01L2300/18 , B01L2400/0406 , B01L2400/049
Abstract: The present disclosure relates to a fluid analyzing device that includes a sensing device for analyzing a fluid sample. The sensing device includes a microchip configured for sensing the fluid sample, and a closed micro-fluidic component for propagating the fluid sample to the microchip. The fluid sample can be provided to the micro-fluidic component via an inlet of the fluid analyzing device. And a vacuum compartment, which is air-tight connected to the sensing device, can create in the micro-fluidic component a suction force suitable for propagating the fluid sample through the micro-fluidic component.
-
-
-
-
-
-
-
-
-
Search Results
23
records
(took 0.017 seconds)
