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    Use of diacetyl dimer as an aromatic and/or flavouring substance
    11.
    发明授权
    Use of diacetyl dimer as an aromatic and/or flavouring substance 失效
    使用二乙酰二聚体作为芳香和/或调味物质

    公开(公告)号：US08287934B2

    公开(公告)日：2012-10-16

    申请号：US12300820

    申请日：2007-05-07

    申请人： Jakob Ley ,  Berthold Weber ,  Gerhard Krammer ,  Ingo Reiss ,  Heinz-Jürgen Bertram ,  Ian Gatfield ,  Petra Hoffmann-Lücke

    发明人： Jakob Ley ,  Berthold Weber ,  Gerhard Krammer ,  Ingo Reiss ,  Heinz-Jürgen Bertram ,  Ian Gatfield ,  Petra Hoffmann-Lücke

    IPC分类号： A23L1/22 ,  A61K8/02

    CPC分类号： A23C9/1307 ,  A21D2/14 ,  A21D13/40 ,  A21D13/80 ,  A23C9/156 ,  A23D7/0056 ,  A23D7/015 ,  A23G3/36 ,  A23G4/06 ,  A23G9/32 ,  A23L19/00 ,  A23L27/206 ,  C12C5/026 ,  C12G1/00 ,  C12G3/06

    摘要： The invention relates to the use of 5-acetyl-2,5-dimethyl-2-hydroxy-tetrahydrofuran-3-one (diacetyl dimer of formula (I)) in the form of one of its stereoisomers or in the form of a mixture consisting of or containing two, three or four of its stereoisomers (i) for imparting, intensifying and/or modifying a creamy and/or fatty sensation in the mouth, (ii) for imparting, intensifying and/or modifying a sweet, buttery, cream-like and/or creamy flavor; and/or (iii) as an aromatic and/or flavoring substance. The invention furthermore relates to a process (i) for imparting, intensifying and/or modifying a creamy and/or fatty sensation in the mouth, (ii) for imparting, intensifying and/or modifying a sweet, buttery, cream-like and/or creamy flavor, to corresponding aromatic compositions, to formulations selected from a nutrition formulation (foodstuff), an oral hygiene formulation, a luxury product formulation, a formulation for oral pharmaceutical use or a semi-finished good formulation for the preparation of nutrition formulations or luxury product formulations, as well as preparations comprising one or more of said compositions and/or formulations.

    摘要翻译： 本发明涉及其一种立体异构体形式的5-乙酰基-2,5-二甲基-2-羟基 - 四氢呋喃-3-酮（式（I）的二乙酰二聚体）或混合物形式的用途 包含或含有二，三或四种立体异构体（i）用于赋予，增强和/或改变口腔中的乳状和/或脂肪感觉，（ii）用于赋予，增强和/或改变甜味， 奶油状和/或奶油味; 和/或（iii）作为芳香和/或调味物质。 本发明还涉及一种用于赋予，增强和/或改变口腔中的乳状和/或脂肪感觉的方法（i），（ii）用于赋予，加强和/或改变甜味，奶油状和/ 或奶油味，与相应的芳香族组合物相对于选自营养制剂（食品），口腔卫生制剂，豪华产品制剂，用于口服药物用途的制剂或用于制备营养制剂的半成品良好制剂的制剂，或 豪华产品制剂，以及包含一种或多种所述组合物和/或制剂的制剂。

    AROMA COMPOSITIONS OF ALKAMIDES WITH HESPERETIN AND/OR 4-HYDROXYDIHYDROCHALCONES AND SALTS THEREOF FOR ENHANCING SWEET SENSORY IMPRESSIONS
    14.
    发明申请
    AROMA COMPOSITIONS OF ALKAMIDES WITH HESPERETIN AND/OR 4-HYDROXYDIHYDROCHALCONES AND SALTS THEREOF FOR ENHANCING SWEET SENSORY IMPRESSIONS 审中-公开
    含有HESPERETIN和/或4-羟基二氢吲哚的碱金属组合物及其盐，用于增强甜味剂的敏感性

    公开(公告)号：US20080242740A1

    公开(公告)日：2008-10-02

    申请号：US12058088

    申请日：2008-03-28

    申请人： Jakob Ley ,  Kathrin Freiherr ,  Gerhard Krammer ,  Gerald Reinders

    发明人： Jakob Ley ,  Kathrin Freiherr ,  Gerhard Krammer ,  Gerald Reinders

    IPC分类号： A23L1/236 ,  A61K47/16

    CPC分类号： C07C49/83 ,  A23C9/1307 ,  A23C9/156 ,  A23C11/103 ,  A23L2/56 ,  A23L7/139 ,  A23L27/2028 ,  A23L27/204 ,  A23L27/2052 ,  A23L27/30 ,  A23L27/63 ,  A23V2002/00 ,  C07C49/84 ,  A23V2200/16 ,  A23V2250/25 ,  A23V2250/21164 ,  A23V2250/5114 ,  A23V2250/5028

    摘要： The invention primarily relates to aroma compositions of (i) certain saliva-stimulating alkamides having a tingling, pungent and/or hot flavor (such as for example pellitorines, spilanthol) with (ii) hesperetin (5,7-dihydroxy-3-(3-hydroxy-4-methoxyphenyl)-chroman-4-one) or the enantiomers and/or salts thereof and/or (iii) 4-hydroxydihydrochalcones (3-(4-hydroxyphenyl)-1-phenylpropan-1-ones) and/or the salts thereof, the use thereof to enhance the sweet flavor of sweet-tasting substances or the sweet odor impression of aroma substances which give rise to a sweet odor impression, but in particular to enhance the sweet initial flavor or odor (initial sweetness). The invention thus relates to the use of said aroma compositions as general sweetness enhancers and enhancers of initial sweetness. The invention further relates to certain preparations which contain an effective amount of said aroma compositions of (i) alkamides (such as in particular pellitorines, spilanthol) with (ii) hesperetin or the enantiomers and/or salts thereof and/or (iii) 4-hydroxydihydrochalcones and/or the salts thereof and methods for enhancing the sweet flavor or initial sweetness of a sweet-tasting substance or the sweet odor impression or initial sweetness of an aroma substance which gives rise to a sweet odor impression. The invention also relates to the use of certain alkamides (i) to enhance the initial sweetness of a preparation comprising (ii) hesperetin or the enantiomers and/or salts thereof and/or (iii) 4-hydroxydihydrochalcones and/or the salts thereof and (b) sweet-tasting substances and/or (c) aroma substances which give rise to a sweet odor impression.

    摘要翻译： 本发明主要涉及（i）具有刺痛，刺鼻和/或热风味的某些唾液刺激性烷酰胺（例如，扑地酮，滑液甾醇）与（ii）橙皮素（5,7-二羟基-3-（ 3-羟基-4-甲氧基苯基） - 苯并二氢吡喃-4-酮）或其对映异构体和/或盐和/或（iii）4-羟基二氢鲸蜡酮（3-（4-羟基苯基）-1-苯基丙-1-酮）和 /或其盐，其用于增强甜味物质的甜味或芳香物质的甜味气味，产生甜味气味，特别是增强甜味初始风味或气味（初始甜度 ）。 因此，本发明涉及所述芳香组合物作为初始甜味的一般甜味增强剂和增强剂的用途。 本发明进一步涉及含有有效量的所述芳香组合物的（i）烷酰胺（如特别是pellitorine，spantanthol）与（ii）橙皮素或其对映异构体和/或盐和/或（iii）4 - 羟基二氢鲸脑酯和/或其盐，以及用于增强甜味物质的甜味或初始甜味或芳香物质的甜味气味或初始甜度的方法，其产生甜味气味。 本发明还涉及某些烷酰胺（i）增强包含（ii）橙皮素或其对映异构体和/或盐和/或（iii）4-羟基二氢樟脑和/或其盐的制剂的初始甜度的用途，以及 （b）甜味物质和/或（c）产生甜味气味的香气物质。

    Use of diacetyl trimer as an aromatic and flavouring substance
    17.
    发明授权
    Use of diacetyl trimer as an aromatic and flavouring substance 有权
    使用二乙酰三聚体作为芳香和调味物质

    公开(公告)号：US08318711B2

    公开(公告)日：2012-11-27

    申请号：US11720582

    申请日：2005-11-30

    申请人： Ian Gatfield ,  Jakob Ley ,  Ingo Reiss ,  Günter Kindel ,  Gerhard Krammer

    发明人： Ian Gatfield ,  Jakob Ley ,  Ingo Reiss ,  Günter Kindel ,  Gerhard Krammer

    IPC分类号： A01N43/00 ,  A01N35/00 ,  A61K31/33 ,  A61K31/12

    CPC分类号： A23L27/88 ,  A23L27/86

    摘要： The invention relates to the use of 2,5-diacetyl-3a,5,6,6a-tetrahydro-6a-hydroxy-2,3a,5-trimethylfuro[2,3-d]-1,3-dioxole (diacetyl trimer) of the formula in the form of one of its stereoisomers or in the form of a mixture consisting of or containing two or more of the stereoisomers (i) as an odoriferous or aromatic substance, (ii) for imparting, intensifying and/or modifying a creamy and/or fatty sensation in the mouth, (iii) for imparting, intensifying and/or modifying a sweet, buttery, cream-like and/or creamy flavor, and/or (iv) for masking a bitter flavor. The invention furthermore relates to corresponding aromatic compositions as well as compositions which serve for nutrition, oral hygiene, consumption for pleasure or for oral pharmaceutical use.

    摘要翻译： 本发明涉及2,5-二乙酰基-3,3,5,6,6a-四氢-6a-羟基-2,3a，5-三甲基呋喃并[2,3-d] -1,3-二氧杂环戊烯（二乙酰基三聚体 ）式中其一种立体异构体形式或以由两种或多种立体异构体组成的混合物形式的混合物（i）作为有气味或芳族物质，（ii）用于赋予，增强和/或改变 （iii）用于赋予，加强和/或改变甜的，黄油状，奶油状和/或奶油味，和/或（iv）掩蔽苦味的口香糖和/或脂肪感觉。 本发明还涉及相应的芳族组合物以及用于营养，口腔卫生，快乐消费或口服药物使用的组合物。

    USE OF 4-HYDROXYDIHYDROCHALCONES AND THEIR SALTS FOR ENHANCING AN IMPRESSION OF SWEETNESS
    18.
    发明申请
    USE OF 4-HYDROXYDIHYDROCHALCONES AND THEIR SALTS FOR ENHANCING AN IMPRESSION OF SWEETNESS 有权
    使用4-羟基二氢黄酮及其盐，以增强甜味剂的消耗

    公开(公告)号：US20100233102A1

    公开(公告)日：2010-09-16

    申请号：US12293585

    申请日：2007-03-21

    申请人： Gerhard Krammer ,  Jakob Ley ,  Thomas Riess ,  Martin Haug ,  Susanne Paetz ,  Günter Kindel ,  Ralph Schmidtmann

    发明人： Gerhard Krammer ,  Jakob Ley ,  Thomas Riess ,  Martin Haug ,  Susanne Paetz ,  Günter Kindel ,  Ralph Schmidtmann

    IPC分类号： A61K8/64 ,  A23L1/236 ,  A61K8/35 ,  A61Q11/00

    CPC分类号： A21D2/02 ,  A21D2/08 ,  A21D2/181 ,  A21D2/24 ,  A21D2/26 ,  A23C9/1307 ,  A23C9/1544 ,  A23G1/32 ,  A23G3/36 ,  A23G4/06 ,  A23G9/32 ,  A23L2/60 ,  A23L27/00 ,  A23L27/30 ,  A23L27/88 ,  A23L33/20 ,  A23V2002/00 ,  A61K8/02 ,  A61K8/35 ,  A61K8/498 ,  A61K2800/70 ,  A61Q11/00 ,  C07C45/62 ,  C07C45/74 ,  C07C49/84 ,  C11B9/0061 ,  A23V2200/16 ,  A23V2250/25

    摘要： The invention provides the use of a 4-hydroxydihydrochalcone of the formula (I) wherein R1, R2, R3 and R4 each, independently, represent H, OH or O-alkyl, with the proviso that at least one of the groups R1, R2 or R3 represents OH, a salt of such a 4-hydroxydihydrochalcone of the formula (I), a mixture containing or consisting of two or more different 4-hydroxydihydrochalcones of the formula (I), wherein R1, R2, R3 and R4 are each defined in the way given above, a mixture containing or consisting of salts of two or more different 4-hydroxydihydrochalcones of the formula (I), wherein R1, R2, R3 and R4 are each defined in the way given above or a mixture containing or consisting of a 4-hydroxydihydrochalcone of the formula (I) or two or more different 4-hydroxydihydrochalcones of the formula (I), wherein R1, R2, R3 and R4 are each defined in the way given above, and a salt of a 4-hydroxydihydrochalcone of the formula (I) or two or more salts of different 4-hydroxydihydrochalcones of the formula (I), wherein R1, R2, R3 and R4 are each defined in the way given above, to enhance the sweet taste of a sweet-tasting substance or the impression of a sweet smell of a flavouring that gives an impression of a sweet smell.

    摘要翻译： 本发明提供式（I）的4-羟基二氢查耳酮的用途，其中R 1，R 2，R 3和R 4各自独立地代表H，OH或O-烷基，条件是R1，R2中的至少一个 或R 3表示OH，式（I）的这种4-羟基二氢查耳酮的盐，包含或由两种或更多种式（I）的不同的4-羟基二氢樟脑酮组成的混合物，其中R 1，R 2，R 3和R 4各自为 以上述方式定义的含有式（I）的两种或更多种不同的4-羟基二氢鲸脑的盐或由其组成的混合物，其中R 1，R 2，R 3和R 4各自以上述方式定义，或含有或 由式（I）的4-羟基二氢查耳酮或两种或多种不同的式（I）的4-羟基二氢鲸蜡酮组成，其中R 1，R 2，R 3和R 4各自以上述方式定义，并且4 （I）的羟基二氢查耳酮或两种或更多种不同的4-羟基二氢鲸蜡酮的盐 式（I）其中R 1，R 2，R 3和R 4各自以上述方式定义，以增强甜味物质的甜味，或赋予甜味印象的调味剂甜味的印象 闻。

    Use of Diacetyl Trimer as an Aromatic and Flavouring Substance
    19.
    发明申请
    Use of Diacetyl Trimer as an Aromatic and Flavouring Substance 有权
    使用二乙酰三聚体作为芳香和调味物质

    公开(公告)号：US20090208426A1

    公开(公告)日：2009-08-20

    申请号：US11720582

    申请日：2005-11-30

    申请人： Ian Gatfield ,  Jakob Ley ,  Ingo Reiss ,  Günter Kindel ,  Gerhard Krammer

    发明人： Ian Gatfield ,  Jakob Ley ,  Ingo Reiss ,  Günter Kindel ,  Gerhard Krammer

    IPC分类号： A61K8/49 ,  C07D317/44 ,  A23L1/226 ,  A61K31/357 ,  A61Q11/00

    CPC分类号： A23L27/88 ,  A23L27/86

    摘要： The invention relates to the use of 2,5-diacetyl-3a,5,6,6a-tetrahydro-6a-hydroxy-2,3a,5-trimethylfuro[2,3-d]-1,3-dioxole (diacetyl trimer) of the formula in the form of one of its stereoisomers or in the form of a mixture consisting of or containing two or more of the stereoisomers (i) as an odoriferous or aromatic substance, (ii) for imparting, intensifying and/or modifying a creamy and/or fatty sensation in the mouth, (iii) for imparting, intensifying and/or modifying a sweet, buttery, cream-like and/or creamy flavour, and/or (iv) for masking a bitter flavour. The invention furthermore relates to corresponding aromatic compositions as well as compositions which serve for nutrition, oral hygiene, consumption for pleasure or for oral pharmaceutical use.

    摘要翻译： 本发明涉及2,5-二乙酰基-3,3,5,6,6a-四氢-6a-羟基-2,3a，5-三甲基呋喃并[2,3-d] -1,3-二氧杂环戊烯（二乙酰基三聚体 ）式中其一种立体异构体形式或以由两种或多种立体异构体组成的混合物形式的混合物（i）作为有气味或芳族物质，（ii）用于赋予，增强和/或改变 （iii）用于赋予，加强和/或改变甜的，黄油状，奶油状和/或奶油味，和/或（iv）掩蔽苦味的口香糖和/或脂肪感觉。 本发明还涉及相应的芳族组合物以及用于营养，口腔卫生，快乐消费或口服药物使用的组合物。

    Hydroxybenzoic Acid Amides and the Use Thereof For Masking Bitter Taste
    20.
    发明申请
    Hydroxybenzoic Acid Amides and the Use Thereof For Masking Bitter Taste 审中-公开
    羟基苯甲酸酰胺及其用于掩蔽苦味的用途

    公开(公告)号：US20080214675A1

    公开(公告)日：2008-09-04

    申请号：US11574277

    申请日：2005-08-02

    申请人： Jakob Ley ,  Heinz-Jurgen Bertram ,  Gunter Kindel ,  Gerhard Krammer

    发明人： Jakob Ley ,  Heinz-Jurgen Bertram ,  Gunter Kindel ,  Gerhard Krammer

    IPC分类号： A61K31/166 ,  C07C233/73 ,  A23L1/22

    CPC分类号： A61Q11/00 ,  A61K8/42 ,  C07C235/48 ,  C07C235/60

    摘要： The use is described of hydroxybenzoic acid amides having formula (I) wherein R1 to R5 mutually independently denote hydrogen, hydroxy, methoxy or ethoxy, with the proviso that at least one of the radicals R1 to R5 denotes hydroxy. and R6 denotes hydrogen, methyl or ethyl and n denotes 1 or 2, their salts and mixtures thereof, to mask or reduce the unpleasant flavour impression of an unpleasantly tasting substance and/or to strengthen the sweet flavour impression of a sweet substance.

    摘要翻译： 描述了具有式（I）的羟基苯甲酸酰胺，其中R 1至R 5相互独立地表示氢，羟基，甲氧基或乙氧基，条件是至少 基团R 1至R 5之一表示羟基。 和R 6表示氢，甲基或乙基，n表示1或2，它们的盐和混合物，以掩盖或减少不愉快的品尝物质的不愉快的风味印象和/或加强甜味 一种甜的物质的印象。