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公开(公告)号：US20220273555A1
公开(公告)日：2022-09-01
申请号：US16860121
申请日：2020-04-28
Applicant: ModernaTX, Inc.
Inventor： Stephane BANCEL , Tirtha CHAKRABORTY , Antonin DE FOUGEROLLES , Sayda M. ELBASHIR , Matthias JOHN , Atanu ROY , Susan WHORISKEY , Kristy M. WOOD , Paul HATALA , Jason P. SCHRUM , Kenechi EJEBE , Jeff Lynn ELLSWORTH , Justin GUILD
Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
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Patent Agency Ranking
公开(公告)号：US20190240351A1
公开(公告)日：2019-08-08
申请号：US15789138
申请日：2017-10-20
Applicant: ModernaTX, Inc.
Inventor： Stephane BANCEL , Tirtha CHAKRABORTY , Antonin DE FOUGEROLLES , Sayda M. ELBASHIR , Jeff Lynn ELLSWORTH , Kenechi EJEBE , Justin GUILD , Matthias JOHN , Paul HATALA , Atanu ROY , Jason P. SCHRUM , Susan WHORISKEY , Kristy M. WOOD
IPC: A61K48/00 , C07K14/535 , C07K14/47 , C07K14/515 , A61K9/127 , C12N9/64 , A61K31/7115 , A61K47/54 , A61K9/51 , A61K9/14 , C12N15/87 , C12N15/85 , C12N9/00 , C07K14/705 , C07K14/62 , C07K14/505 , C07K14/485 , C07K14/435 , A61K38/45 , A61K38/17 , A61K38/48 , C07K14/525 , C07K14/56 , C07K16/00 , C12P21/00 , A61K38/18 , A61K38/19 , A61K38/21 , C12P13/04 , C12N15/52 , C12N15/11 , C12N9/88 , C12N9/42 , C12N9/24 , C12N9/16 , C12N9/10 , C07K14/005
CPC classification number: A61K48/0066 , A61K9/1271 , A61K9/145 , A61K9/5123 , A61K9/5146 , A61K9/5153 , A61K31/7115 , A61K38/00 , A61K38/17 , A61K38/177 , A61K38/1816 , A61K38/1891 , A61K38/191 , A61K38/193 , A61K38/212 , A61K38/45 , A61K38/4846 , A61K47/543 , A61K48/0033 , A61K48/005 , A61K48/0075 , C07H21/02 , C07K14/005 , C07K14/435 , C07K14/43595 , C07K14/47 , C07K14/4705 , C07K14/4713 , C07K14/4723 , C07K14/4746 , C07K14/475 , C07K14/485 , C07K14/495 , C07K14/505 , C07K14/515 , C07K14/525 , C07K14/535 , C07K14/5418 , C07K14/56 , C07K14/61 , C07K14/62 , C07K14/705 , C07K14/745 , C07K16/00 , C07K16/2863 , C07K16/2887 , C07K16/40 , C12N9/0069 , C12N9/0091 , C12N9/1051 , C12N9/1241 , C12N9/16 , C12N9/2402 , C12N9/2445 , C12N9/6435 , C12N9/6437 , C12N9/644 , C12N9/6443 , C12N9/6451 , C12N9/88 , C12N9/93 , C12N15/11 , C12N15/52 , C12N15/85 , C12N15/87 , C12P13/04 , C12P21/00 , C12P21/005 , C12Y113/12007 , C12Y116/03001 , C12Y207/07012 , C12Y304/21007 , C12Y304/21022 , C12Y304/21027 , C12Y403/02001 , C12Y603/02019 , Y02A50/401 , Y02A50/411 , Y02A50/414 , Y02A50/415 , Y02A50/423 , Y02A50/463 , Y02A50/491
Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
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13.发明申请公开(公告)号：US20180086807A1
公开(公告)日：2018-03-29
申请号：US15440523
申请日：2017-02-23
Applicant: ModernaTX, Inc.
Inventor： Stephane BANCEL , Tirtha CHAKRABORTY , Antonin DE FOUGEROLLES , Sayda M. ELBASHIR , Matthias JOHN , Atanu ROY , Susan WHORISKEY , Kristy M. WOOD , Paul HATALA , Jason P. SCHRUM , Kenechi EJEBE , Jeff Lynn ELLSWORTH , Justin GUILD
IPC: C07K14/535 , A61K9/127 , C12N15/88 , C12N15/85 , C12N9/64 , C12N9/02 , C07K19/00 , C07K16/32 , C07K16/28 , C07K14/75 , C07K14/745 , C07K14/565 , C07K14/56 , C07K14/525 , C07K14/505 , C07K14/475 , C07K14/47 , A61K48/00 , A61K47/10 , A61K39/395 , A61K38/48 , A61K38/44 , A61K38/36 , A61K38/21 , A61K38/19 , A61K38/18 , A61K38/17 , A61K31/7088 , A61K9/50 , A61K9/14 , A61K9/00
CPC classification number: C07K14/535 , A61K9/0019 , A61K9/1271 , A61K9/1272 , A61K9/1277 , A61K9/14 , A61K9/5031 , A61K31/7088 , A61K38/1767 , A61K38/1816 , A61K38/1866 , A61K38/191 , A61K38/193 , A61K38/212 , A61K38/215 , A61K38/36 , A61K38/363 , A61K38/44 , A61K38/4833 , A61K38/4846 , A61K39/3955 , A61K47/10 , A61K47/54 , A61K47/542 , A61K48/00 , A61K48/0033 , A61K48/0066 , A61K48/0075 , C07K14/47 , C07K14/475 , C07K14/505 , C07K14/525 , C07K14/56 , C07K14/565 , C07K14/745 , C07K14/75 , C07K16/2887 , C07K16/32 , C07K19/00 , C12N9/0069 , C12N9/644 , C12N15/85 , C12N15/88 , C12N2840/00 , C12Y113/12007 , C12Y304/21005 , C12Y304/21022
Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
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14.发明申请公开(公告)号：US20180002393A1
公开(公告)日：2018-01-04
申请号：US15425813
申请日：2017-02-06
Applicant: ModernaTX, Inc.
Inventor： Stephane BANCEL , Tirtha CHAKRABORTY , Antonin DE FOUGEROLLES , Sayda M. ELBASHIR , Matthias JOHN , Atanu ROY , Susan WHORISKEY , Kristy M. WOOD , Paul HATALA , Jason P. SCHRUM , Kenechi EJEBE , Jeff Lynn ELLSWORTH , Justin GUILD
IPC: C07K14/535 , C12N15/88 , C12N15/85 , C12N9/64 , C12N9/02 , C07K19/00 , C07K16/32 , C07K16/28 , C07K14/75 , C07K14/745 , C07K14/565 , C07K14/56 , C07K14/525 , C07K14/505 , C07K14/475 , C07K14/47 , A61K48/00 , A61K47/60 , A61K47/10 , A61K39/395 , A61K38/48 , A61K38/44 , A61K38/36 , A61K38/21 , A61K38/19 , A61K38/18 , A61K38/17 , A61K31/7088 , A61K9/50 , A61K9/14 , A61K9/127 , A61K9/00
CPC classification number: C07K14/535 , A61K9/0019 , A61K9/0043 , A61K9/1271 , A61K9/1272 , A61K9/1277 , A61K9/14 , A61K9/145 , A61K9/5031 , A61K31/7088 , A61K31/7115 , A61K38/1767 , A61K38/1816 , A61K38/1866 , A61K38/191 , A61K38/193 , A61K38/212 , A61K38/215 , A61K38/36 , A61K38/363 , A61K38/44 , A61K38/4833 , A61K38/4846 , A61K39/3955 , A61K47/10 , A61K47/60 , A61K48/00 , A61K48/0033 , A61K48/0066 , A61K48/0075 , C07K14/47 , C07K14/475 , C07K14/505 , C07K14/525 , C07K14/56 , C07K14/565 , C07K14/745 , C07K14/75 , C07K16/2887 , C07K16/32 , C07K19/00 , C12N9/0069 , C12N9/644 , C12N15/85 , C12N15/88 , C12N2840/00 , C12Y113/12007 , C12Y304/21005 , C12Y304/21022 , A61K2300/00
Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of oncology-related polynucleotides, oncology-related primary transcripts and oncology-related mmRNA molecules.
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公开(公告)号：US20180000910A1
公开(公告)日：2018-01-04
申请号：US15429532
申请日：2017-02-10
Applicant: ModernaTX, Inc.
Inventor： Tirtha CHAKRABORTY , Stephane BANCEL , Stephen G. HOGE , Atanu ROY , Antonin de FOUGEROLLES , Noubar B. AFEYAN
Abstract: The invention relates to compositions and methods for the manufacture and optimization of modified mRNA molecules via optimization of their terminal architecture.
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公开(公告)号：US20170028085A1
公开(公告)日：2017-02-02
申请号：US15294339
申请日：2016-10-14
Applicant: ModernaTX, Inc.
Inventor： Stephane BANCEL , Tirtha CHAKRABORTY , Antonin DE FOUGEROLLES , Sayda M. ELBASHIR , Matthias JOHN , Atanu ROY , Susan WHORISKEY , Kristy M. Wood , Paul HATALA , Jason P. SCHRUM , Kenechi EJEBE , Jeff Lynn ELLSWORTH , Justin GUILD , Ron WEISS
IPC: A61K48/00 , A61K9/50 , C07K14/535 , A61K38/19 , A61K38/48 , C07K14/505 , A61K38/18 , C07K14/525 , C07K14/565 , A61K38/21 , C07K16/32 , A61K39/395 , C07K16/28 , C07K14/475 , A61K38/44 , C07K14/56 , C07K14/745 , A61K38/36 , C07K14/75 , C12N9/64 , C12N9/02 , A61K9/127
CPC classification number: C07K14/535 , A61K9/0019 , A61K9/1271 , A61K9/1272 , A61K9/1277 , A61K9/14 , A61K9/5031 , A61K31/7088 , A61K38/1767 , A61K38/1816 , A61K38/1866 , A61K38/191 , A61K38/193 , A61K38/212 , A61K38/215 , A61K38/36 , A61K38/363 , A61K38/44 , A61K38/4833 , A61K38/4846 , A61K39/3955 , A61K47/10 , A61K47/54 , A61K47/542 , A61K48/00 , A61K48/0033 , A61K48/0066 , A61K48/0075 , C07K14/47 , C07K14/475 , C07K14/505 , C07K14/525 , C07K14/56 , C07K14/565 , C07K14/745 , C07K14/75 , C07K16/2887 , C07K16/32 , C07K19/00 , C12N9/0069 , C12N9/644 , C12N15/85 , C12N15/88 , C12N2840/00 , C12Y113/12007 , C12Y304/21005 , C12Y304/21022
Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
Abstract translation: 本发明涉及用于制备，制造和治疗性使用多核苷酸，初级转录物和mmRNA分子的组合物和方法。
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