Abstract:
A security system architecture and method of operation that combines a local security network with control panel and sensors, a central monitoring station (CMS), and a separate operator computer server that provides a web portal for both the homeowner and CMS, that maintains a persistent connection between the control panel and CMS allowing failsafe dual-path signaling. This dual-path signaling technique is extended to provide an effective “smash and grab alarm”, and various approaches to dual-path signal management are disclosed including handshaking, persistent domain monitoring, relayed Operator 3-to-CMS signaling, etc. Improved processes for remotely accessing video are also disclosed along with an improved process for remote control panel configuration, and control panel interfacing with home automation appliances.
Abstract:
A durable blade, a method of manufacturing it and a method of repairing blades are described and claimed. Durable blade includes an airfoil having a pressure side and a suction side, a midspan shroud located on the airfoil, at least one recess on the midspan shroud and a wear pad attached to the recess of the midspan shroud.
Abstract:
Kits and devices for performing a method of detecting a molecule associated with viability of one or more cells or organisms in a sample are provided. The method comprises the initial step of contacting the sample with an enzyme, which enzyme is capable of adding or removing a chemical moiety to or from a nucleic acid molecule in the presence of the molecule associated with viability of the one or more cells or organisms. This thereby generates a novel detectable nucleic acid molecule. The next step involves detecting the presence of the molecule associated with viability of the one or more cells or organisms by detecting the novel nucleic acid molecule generated only in the presence of the molecule associated with viability of the one or more cells or organisms. A most preferred molecule associated with viability is ATP, although NAD may also be detected. A preferred enzyme for use in the methods is ligase. The kits and devices for performing the method have numerous applications, in particular in monitoring viability of cells, toxicology testing and determining whether there is contamination in a sample or on a surface.
Abstract:
The present invention relates to compounds of formula 1 or pharmaceutically acceptable salts thereof, wherein one of R1 and R2 is methyl, ethyl or isopropyl, and the other is H; R3 and R4 are each independently H, branched or unbranched C1-C6 alkyl, or aryl, and wherein at least one of R3 and R4 is other than H; R5 is a branched or unbranched C1-C5 alkyl group or a C1-C6 cycloalkyl group, each of which may be optionally substituted with one or more OH groups; R6, R7, R8 and R9 are each independently H, halogen, NO2, OH, OMe, CN, NH2, COOH, CONH2, or SO2NH2. A further aspect of the invention relates to pharmaceutical compositions comprising compounds of formula 1, and the use of said compounds in treating proliferative disorders, viral disorders, stroke, alopecia, CNS disorders, neurodegenerative disorders, or diabetes.
Abstract:
A microelectronic assembly includes a microelectronic package having a microelectronic element with faces and contacts, a flexible substrate spaced from and overlying a first face of the microelectronic element, and a plurality of conductive posts extending from the flexible substrate and projecting away from the first face of the microelectronic element, at least some of the conductive posts being electrically interconnected with the microelectronic element. The package includes a plurality of support elements disposed between the microelectronic element and the substrate and supporting the flexible substrate over the microelectronic element. At least some of the conductive posts are offset from the support elements. The assembly includes a circuitized substrate having conductive pads confronting the conductive posts of the microelectronic package, whereby the conductive posts are electrically interconnected with the conductive pads.
Abstract:
An assembly is provided which includes a first circuit panel having a top surface, a first dielectric element and first conductive traces disposed on the first dielectric element. In addition, a second circuit panel has a bottom surface, a second dielectric element and second conductive traces disposed on the second dielectric element, where at least a portion of the second circuit panel overlies at least a portion of the first circuit panel. The assembly further includes an interconnect circuit panel having a third dielectric element which has a front surface, a rear surface opposite the front surface, a top end extending between the front and rear surfaces, a bottom end extending between the front and rear surfaces, and a plurality of interconnect traces disposed on the dielectric element. The bottom end of the interconnect element abuts the top surface of the first circuit panel and the top end abuts the bottom surface of the second circuit panel, where at least some of the first conductive traces are in conductive communication with the second conductive traces through the interconnect traces.
Abstract:
A dispenser for dispensing same-size discrete articles (P) comprises a holder (34, 36, 44) for holding a plurality of such articles in a stack, the holder having a top, a bottom (44, 46), and an exit opening (60) at the bottom, through which the lowermost article in the stack can leave the holder in a transverse direction. It further comprises means (38, 40, 16, 18) defining a pathway for guiding said articles from the exit opening to, and over, the top of the holder, with each article in the pathway pushing the article ahead of it along the pathway. The arrangement is such that the articles are visible while in transit along the pathway to the top of the holder.
Abstract:
A method for constructing prefabricated modular building panels includes providing a plurality of full wall height panels in several widths and full wall height corner elements which can be assembled to provide walls for a building of almost any size. The method also includes providing less than full height header and sill panels in several widths which can be used to install windows and doors. A window is installed between a header and sill panel having a width which is greater than the width of the window by placing studs between the header and sill panels at each side of the window and at each side of the header and sill panels. A door is installed under a header panel having a width which is greater than the width of the door by building a frame on each side of the door below the header panel. The panels are made with a frame of interconnected steel studs and steel top and bottom tracks. Pieces of structural building material are rigidly attached to the tracks and project from the front edges of the track by a predetermined distance. Strips of insulating material attached to the front edges of the studs have a thickness substantially equal to this first predetermined distance.
Abstract:
A security system architecture and method of operation that combines a local security network with control panel and sensors, a central monitoring station (CMS), and a separate operator computer server that provides a web portal for both the homeowner and CMS, that maintains a persistent connection between the control panel and CMS allowing failsafe dual-path signaling. This dual-path signaling technique is extended to provide an effective “smash and grab alarm”, and various approaches to dual-path signal management are disclosed including handshaking, persistent domain monitoring, relayed Operator 3-to-CMS signaling, etc. Improved processes for remotely accessing video are also disclosed along with an improved process for remote control panel configuration, and control panel interfacing with home automation appliances.
Abstract:
A method of detecting a ligase expressing micro-organism in a sample comprises steps of treating the sample under conditions that inhibit the activity of ATP-dependent ligase from mammalian cells but which do not inhibit the activity of the microbial ligases, contacting the sample or a portion of the sample with a nucleic acid molecule which acts as a substrate for ligase activity in the sample, incubating the thus contacted sample under conditions suitable for ligase activity; and specifically determining the presence and/or the amount of a ligated nucleic acid molecule resulting from the action of the ligase on the substrate nucleic acid molecule to indicate the presence of the ligase expressing micro-organism. The micro-organism may be a fungus or a bacterium or both. High pH conditions may be employed to inactivate mammalian ligases. Related kits are described.