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公开(公告)号:US20160076099A1
公开(公告)日:2016-03-17
申请号:US14848311
申请日:2015-09-08
Applicant: Bio-Rad Laboratories, Inc.
Inventor: John F. Regan , Serge Saxonov , Michael Y. Lucero , Benjamin J. Hindson , Phillip Belgrader , Simant Dube , Austin P. So , Jeffrey C. Mellen , Nicholas J. Heredia , Kevin D. Ness , Billy W. Colston, Jr.
IPC: C12Q1/68
CPC classification number: C12Q1/6883 , C12Q1/683 , C12Q1/6858 , C12Q2600/158 , C12Q2600/172 , C12Q2537/16 , C12Q2563/159 , C12Q2537/165
Abstract: Provided herein are improved methods, compositions, and kits for analysis of nucleic acids. The improved methods, compositions, and kits can enable copy number estimation of a nucleic acid in a sample. Also provided herein are methods, compositions, and kits for determining the linkage of two or more copies of a target nucleic acid in a sample (e.g. whether the two or more copies are on the same chromosome or different chromosomes) or for phasing alleles.
Abstract translation: 本文提供了用于分析核酸的改进的方法,组合物和试剂盒。 改进的方法,组合物和试剂盒可以使得样品中核酸的拷贝数估计可以进行。 本文还提供了用于确定样品中靶核酸的两个或多个拷贝(例如两个或多个拷贝是在同一染色体上还是在不同染色体上)或用于定相等位基因的连接的方法,组合物和试剂盒。
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公开(公告)号:US20140200164A1
公开(公告)日:2014-07-17
申请号:US14159410
申请日:2014-01-20
Applicant: Bio-Rad Laboratories, Inc.
Inventor: Anthony J. Makarewicz, JR. , Amy L. Hiddessen , Kevin D. Ness , Donald. A. Masquelier , Billy W. Colston, JR. , Benjamin J. Hindson , Serge Saxonov , Svilen S. Tzonev , Michael Y. Lucero , Ryan T. Koehler
IPC: C12Q1/68
CPC classification number: B01L9/527 , B01F3/0807 , B01F13/0062 , B01F13/0071 , B01L3/0241 , B01L3/502 , B01L3/50273 , B01L3/502761 , B01L3/502784 , B01L3/52 , B01L7/525 , B01L2200/0636 , B01L2200/0647 , B01L2200/0673 , B01L2200/0684 , B01L2200/0689 , B01L2300/0816 , B01L2300/0819 , B01L2300/0861 , B01L2300/0864 , B01L2300/088 , B01L2300/123 , B01L2300/1822 , B01L2400/0478 , B01L2400/0487 , B01L2400/049 , B01L2400/0622 , G01N15/1404 , G01N15/1434 , G01N15/1436 , G01N15/1459 , G01N15/1463 , G01N15/1484 , G01N2015/1006 , G01N2015/1415
Abstract: System, including methods and apparatus, for detection of spaced droplets.
Abstract translation: 用于检测间隔液滴的系统,包括方法和装置。
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