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21.发明授权公开(公告)号：US06498353B2
公开(公告)日：2002-12-24
申请号：US10038525
申请日：2001-10-24
申请人： Robert Nagle , Colin B. Kennedy
发明人： Robert Nagle , Colin B. Kennedy
IPC分类号： G01N1506
CPC分类号： B01L3/5027 , B01L3/502715 , B01L2300/0654 , B01L2300/0816 , B01L2300/0887 , B01L2400/0415 , B01L2400/0487 , G01N21/0303
摘要： The present invention provides microfluidic devices and systems that utilize optical detection systems, and where one or more light altering optical elements are integrated into the body structure of the microfluidic device. The resulting devices perform at least a portion of the optical manipulations used in the optical detection method employed.
摘要翻译： 本发明提供了利用光学检测系统的微流体装置和系统，并且其中一个或多个光改变光学元件被集成到微流体装置的主体结构中。 所得到的装置执行在所采用的光学检测方法中使用的光学操作的至少一部分。
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公开(公告)号：US06488897B2
公开(公告)日：2002-12-03
申请号：US09846694
申请日：2001-05-01
申请人： Robert S. Dubrow , Colin B. Kennedy , Robert Nagle
发明人： Robert S. Dubrow , Colin B. Kennedy , Robert Nagle
IPC分类号： B01L300
CPC分类号： B01L3/502715 , B01L3/5085 , B01L2200/025 , B01L2200/027 , B01L2200/0605 , B01L2200/0689 , B01L2300/0681 , B01L2300/0887 , B01L2300/16 , B01L2400/0406 , B01L2400/0415 , B01L2400/0487 , G01N27/44791 , G01N2035/00148 , Y10T436/25 , Y10T436/25625 , Y10T436/2575
摘要： The present invention provides microfluidic devices that comprise a body structure comprising at least a first microscale channel network disposed therein. The body structure has a plurality of ports disposed in the body structure, where each port is in fluid communication with one or more channels in the first channel network. The devices also include a cover layer comprising a plurality of apertures disposed through the cover layer. The cover layer is mated with the body structure whereby each of the apertures is aligned with a separate one of the plurality of ports.
摘要翻译： 本发明提供了包括主体结构的微流体装置，其包括至少设置在其中的第一微量通道网络。 身体结构具有设置在身体结构中的多个端口，其中每个端口与第一通道网络中的一个或多个通道流体连通。 这些装置还包括覆盖层，其包括穿过覆盖层设置的多个孔。 覆盖层与主体结构配合，由此每个孔与多个端口中的单独一个对准。
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公开(公告)号：US08496875B2
公开(公告)日：2013-07-30
申请号：US11133943
申请日：2005-05-20
IPC分类号： G01N21/00
CPC分类号： G01N35/00584 , B01L3/5027 , B01L3/502715 , B01L9/527 , B01L2300/0819 , G01N21/05 , G01N21/11 , G01N21/13 , G01N35/04 , G01N35/1095 , G01N2021/0346 , G01N2021/058
摘要： The present invention is an automated microfluidic chip processing apparatus that includes a deck for holding at least one microfluidic chip and capable of being accessed by a liquid handling system, a fluid control system, and a detection system, wherein a chip handling device transports the chip from the deck to the fluid control system and the detection system. The present invention also includes a chip for use with an automated microfluidic chip processing apparatus, and a method for processing a microfluidic chip using such an apparatus.
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公开(公告)号：US20120080315A1
公开(公告)日：2012-04-05
申请号：US13290843
申请日：2011-11-07
IPC分类号： G01N27/447 , G01N27/453
CPC分类号： G01N27/44791 , B01L3/5027 , B01L2200/0636 , B01L2200/0689 , B01L2300/021 , B01L2300/0645 , B01L2300/0861 , B01L2400/0421 , G01N27/44717
摘要： The invention provides fluidic devices having incorporated electrodes, systems for using such devices, and methods for manufacturing such devices. The invention also provides fluidic devices configured to absorb joule heating within the device.
摘要翻译： 本发明提供了具有并入电极的流体装置，用于使用这种装置的系统以及用于制造这种装置的方法。 本发明还提供了被配置为吸收装置内的焦耳加热的流体装置。
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公开(公告)号：US06488895B1
公开(公告)日：2002-12-03
申请号：US09568557
申请日：2000-05-09
申请人： Colin B. Kennedy
发明人： Colin B. Kennedy
IPC分类号： B01L302
CPC分类号： B01L3/502715 , B01J2219/0081 , B01L3/502707 , B01L9/527 , B01L2200/027 , B01L2200/028 , B01L2200/0689 , B01L2300/0816 , B01L2300/0864 , B01L2400/0415 , B01L2400/0487
摘要： Multiplexed microfluidic devices include a plurality of modular microfluidic elements, all of which are attached to a common frame or substrate, which itself includes one or more common input elements that are connected to corresponding input elements within several or each of the microfluidic modules for use in common control and/or common detection operations for each of the modules.
摘要翻译： 复数微流体装置包括多个模块化微流体元件，所有这些都是连接到共同的框架或基底上，其本身包括一个或多个公共输入元件，其连接到几个或每个微流体模块内的相应的输入元件，用于 用于每个模块的公共控制和/或常见检测操作。
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公开(公告)号：US06235175B1
公开(公告)日：2001-05-22
申请号：US09165704
申请日：1998-10-02
IPC分类号： G01N2726
CPC分类号： B01L3/50273 , B01L3/502753 , B01L3/502784 , B01L2200/0605 , B01L2300/0816 , B01L2300/0829 , B01L2300/0861 , B01L2300/0867 , B01L2400/0418 , B01L2400/0421 , B01L2400/0487 , G01N27/44791 , Y10S366/02 , Y10S366/03
摘要： The present invention generally provides microfluidic devices which incorporate improved channel and reservoir geometries, as well as methods of using these devices in the analysis, preparation, or other manipulation of fluid borne materials, to achieve higher throughputs of such materials through these devices, with lower cost, material and/or space requirements.
摘要翻译： 本发明通常提供包含改进的通道和储存器几何形状的微流体装置，以及在流体传播材料的分析，制备或其他操作中使用这些装置的方法，以通过这些装置实现更高的这种材料的通过量，具有较低的 成本，材料和/或空间要求。
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公开(公告)号：US6068752A
公开(公告)日：2000-05-30
申请号：US372652
申请日：1999-08-11
CPC分类号： B01L3/50273 , B01L3/502753 , B01L3/502784 , G01N27/44791 , B01L2200/0605 , B01L2300/0816 , B01L2300/0829 , B01L2300/0861 , B01L2300/0867 , B01L2400/0418 , B01L2400/0421 , B01L2400/0487 , Y10S366/02 , Y10S366/03
摘要： The present invention generally provides microfluidic devices which incorporate improved channel and reservoir geometries, as well as methods of using these devices in the analysis, preparation, or other manipulation of fluid borne materials, to achieve higher throughputs of such materials through these devices, with lower cost, material and/or space requirements.
摘要翻译： 本发明通常提供包含改进的通道和储存器几何形状的微流体装置，以及在流体传播材料的分析，制备或其他操作中使用这些装置的方法，以通过这些装置实现更高的这种材料的通过量，具有较低的 成本，材料和/或空间要求。
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公开(公告)号：US5976336A
公开(公告)日：1999-11-02
申请号：US845754
申请日：1997-04-25
IPC分类号： G01N31/20 , B01L3/00 , G01N27/447 , G01N37/00 , G01N27/26
CPC分类号： B01L3/502784 , B01L3/50273 , B01L3/502753 , G01N27/44791 , B01L2200/0605 , B01L2300/0816 , B01L2300/0829 , B01L2300/0861 , B01L2400/0418 , B01L2400/0421 , B01L2400/0487 , Y10T436/143333
摘要： The present invention generally provides microfluidic devices which incorporate improved channel and reservoir geometries, as well as methods of using these devices in the analysis, preparation, or other manipulation of fluid borne materials, to achieve higher throughputs of such materials through these devices, with lower cost, material and/or space requirements.
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公开(公告)号：US5876675A
公开(公告)日：1999-03-02
申请号：US906441
申请日：1997-08-05
申请人： Colin B. Kennedy
发明人： Colin B. Kennedy
IPC分类号： B01L3/00 , B01L9/00 , G01N27/447
CPC分类号： B01L3/502715 , B01L9/527 , G01N27/44791 , B01L2200/025 , B01L2200/087 , B01L2300/0816 , B01L2400/0415
摘要： Microfluidic devices and systems, and particularly, microfluidic devices that are easier to handle by the operator, without damaging, contaminating or otherwise fouling, as a result of manual contact with the device. These microfluidic devices and systems include manual handling structures, to allow handling of the small scale devices with minimal potential for fouling as a result of manual contact with the device.
摘要翻译： 微流体装置和系统，特别是由于与装置的手动接触而易于操作的微流体装置，而不会损坏，污染或以其他方式结垢。 这些微流体装置和系统包括手动处理结构，以允许以与装置的手动接触的结果最小的结垢潜力处理小规模装置。
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公开(公告)号：US20110139274A1
公开(公告)日：2011-06-16
申请号：US13030379
申请日：2011-02-18
CPC分类号： G01N27/44743 , B01L3/5027 , B01L3/502715 , B01L3/502753 , B01L9/527 , B01L2200/027 , B01L2200/0636 , B01L2300/0816 , B01L2300/0887 , B01L2300/1894 , B01L2400/0421 , B01L2400/0481 , G01N27/44717 , G01N27/44791 , G01N30/84 , G01N33/5438 , Y10T29/49826 , Y10T137/8158 , Y10T137/8376
摘要： The invention provides fluidic devices having incorporated electrodes, systems for using such devices, and methods for manufacturing such devices. The invention also provides fluidic devices configured to absorb joule heating within the device.
摘要翻译： 本发明提供了具有并入电极的流体装置，用于使用这种装置的系统以及用于制造这种装置的方法。 本发明还提供了被配置为吸收装置内的焦耳加热的流体装置。
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