ELECTRIC CHARGE CONCENTRATION TYPE DROPLET DISPENSING DEVICE HAVING NONCONDUCTIVE CAPILLARY NOZZLE
    21.
    发明申请
    ELECTRIC CHARGE CONCENTRATION TYPE DROPLET DISPENSING DEVICE HAVING NONCONDUCTIVE CAPILLARY NOZZLE 有权
    具有非导电毛细喷嘴的电荷浓度型滴灌分配装置

    公开(公告)号:US20080017736A1

    公开(公告)日:2008-01-24

    申请号:US11781714

    申请日:2007-07-23

    IPC分类号: B05B5/00

    摘要: Provided is a droplet dispensing device having a nonconductive capillary nozzle. The droplet dispensing device comprises: a nonconductive capillary nozzle disposed in a downward position; a pump connected with the nonconductive capillary nozzle through a hermetically sealed fluid tube and generating a negative pressure to decrease the influence of gravity on a solution within the nonconductive capillary nozzle and the fluid tube; and an open circuit voltage supplier applying a voltage to the solution. The droplet dispensing device supplies the solution by capillary force to regularly maintain the shape of a droplet surface in the tip of the nonconductive capillary nozzle without using a separate driving device.

    摘要翻译: 提供了具有非导电毛细管喷嘴的液滴分配装置。 液滴分配装置包括:设置在向下位置的非导电毛细管喷嘴; 泵,其通过气密密封的流体管与非导电毛细管喷嘴连接并产生负压,以减少重力对非导电毛细管喷嘴和流体管内的溶液的影响; 以及向该溶液施加电压的开路电压供给器。 液滴分配装置通过毛细管力提供溶液以在不使用单独的驱动装置的情况下规定地保持非导电毛细管喷嘴的尖端中的液滴表面的形状。

    METHOD AND APPARATUS FOR DISRUPTING CELLS AND AMPLIFYING NUCLEIC ACIDS USING GOLD NANORODS
    23.
    发明申请
    METHOD AND APPARATUS FOR DISRUPTING CELLS AND AMPLIFYING NUCLEIC ACIDS USING GOLD NANORODS 有权
    破坏细胞的方法和装置,使用金纳多糖放大核酸

    公开(公告)号:US20110212514A1

    公开(公告)日:2011-09-01

    申请号:US13107677

    申请日:2011-05-13

    IPC分类号: C12M1/00 C12M1/02 C12M1/42

    摘要: Provided is a method of disrupting cells comprising adding gold nanorods to a solution containing cells and irradiating the gold nanorods with a laser to disrupt the cells. A method and an apparatus for continuously disrupting cells and amplifying nucleic acids in a single microchamber are also provided, wherein the method comprises introducing a solution containing cells and gold nanorods into a microchamber, irradiating a laser onto the gold nanorods to disrupt the cells, and amplifying a nucleic acid from the disrupted cells in the microchamber.

    摘要翻译: 提供一种破坏细胞的方法,包括向含有细胞的溶液中加入金纳米棒并用激光照射金纳米棒以破坏细胞。 还提供了用于在单个微室中连续破坏细胞和扩增核酸的方法和装置,其中所述方法包括将含有细胞和金纳米棒的溶液引入微室中,将激光照射到金纳米棒上以破坏细胞,以及 在微室中从破碎的细胞中扩增核酸。

    METHOD AND APPARATUS FOR DISRUPTING CELLS AND AMPLIFYING NUCLEIC ACIDS USING GOLD NANORODS
    27.
    发明申请
    METHOD AND APPARATUS FOR DISRUPTING CELLS AND AMPLIFYING NUCLEIC ACIDS USING GOLD NANORODS 有权
    破坏细胞的方法和装置,使用金纳多糖放大核酸

    公开(公告)号:US20080171366A1

    公开(公告)日:2008-07-17

    申请号:US11838550

    申请日:2007-08-14

    IPC分类号: C12N13/00 C12P19/34 C12M1/00

    摘要: Provided is a method of disrupting cells comprising adding gold nanorods to a solution containing cells and irradiating the gold nanorods with a laser to disrupt the cells. A method and an apparatus for continuously disrupting cells and amplifying nucleic acids in a single microchamber are also provided, wherein the method comprises introducing a solution containing cells and gold nanorods into a microchamber, irradiating a laser onto the gold nanorods to disrupt the cells, and amplifying a nucleic acid from the disrupted cells in the microchamber.

    摘要翻译: 提供一种破坏细胞的方法,包括向含有细胞的溶液中加入金纳米棒并用激光照射金纳米棒以破坏细胞。 还提供了用于在单个微室中连续破坏细胞和扩增核酸的方法和装置,其中所述方法包括将含有细胞和金纳米棒的溶液引入微室中,将激光照射到金纳米棒上以破坏细胞,以及 在微室中从破碎的细胞中扩增核酸。

    DEVICE AND METHOD OF SEPARATING CELLS BY USING MAGNETIC FORCE
    29.
    发明申请
    DEVICE AND METHOD OF SEPARATING CELLS BY USING MAGNETIC FORCE 有权
    使用磁力分离细胞的装置和方法

    公开(公告)号:US20120077267A1

    公开(公告)日:2012-03-29

    申请号:US13051251

    申请日:2011-03-18

    IPC分类号: C12N5/00 C12M1/00

    摘要: A cell separation device includes a channel or chamber in which a sample flows or moves, the sample including target cells marked with magnetic particles, and non-target cells, and a magnet which generates a magnetic first force in a first direction with respect to the sample within the channel or chamber. The channel or chamber of the cell separation device is applied with a second force in a second direction opposite to the first direction of the magnetic force. According to the cell separation device and a method of separating cells, the target cells move in the first direction by the magnetic force, and the non-target cells move in the second direction by the second force, by simultaneously applying the magnetic force and the second force in opposing directions, thereby separating the target cells from the non-target cells.

    摘要翻译: 细胞分离装置包括样品流动或移动的通道或室,包括标记有磁性颗粒的靶细胞的样品和非靶细胞,以及相对于第一方向产生第一方向的磁性第一力的磁体 样品在通道或室内。 细胞分离装置的通道或腔室以与磁力的第一方向相反的第二方向施加第二力。 根据细胞分离装置和分离细胞的方法,靶细胞通过磁力在第一方向上移动,非靶细胞通过第二力在第二方向上移动,同时施加磁力和 从而将目标细胞与非靶细胞分离。

    BIOCHEMICAL ANALYZER AND METHOD OF CONTROLLING INTERNAL TEMPERATURE OF THE BIOCHEMICAL ANALYZER
    30.
    发明申请
    BIOCHEMICAL ANALYZER AND METHOD OF CONTROLLING INTERNAL TEMPERATURE OF THE BIOCHEMICAL ANALYZER 有权
    生物化学分析仪及生物化学分析仪内部温度控制方法

    公开(公告)号:US20090022625A1

    公开(公告)日:2009-01-22

    申请号:US11972708

    申请日:2008-01-11

    IPC分类号: B01J19/12 G05D23/19

    摘要: Provided is a biochemical analyzer in which a microfluidic biochemical assay may be performed. The analyzer includes: a microfluidic device loading space including a microfluidic device supporting unit detachably supporting a microfluidic device including an energy application region in which an energy is applied; an energy source loading space including an energy source applying the energy to the radiation application region; and an isolation wall isolating the microfluidic device loading space and the energy source loading space to prevent heat transfer between the microfluidic device loading space and the energy source loading space and including a window through which the energy can be transmitted. A method of controlling an internal temperature of the biochemical analyzer is also provided.

    摘要翻译: 提供了可以进行微流体生化测定的生化分析仪。 所述分析仪包括:微流体装置装载空间,其包括微流体装置支撑单元,其可拆卸地支撑包括其中施加能量的能量施加区域的微流体装置; 能量源装载空间,其包括将能量施加到所述辐射施加区域的能量源; 隔离壁隔离微流体装置加载空间和能量源装载空间,以防止微流体装置加载空间与能量源装载空间之间的热传递并且包括能够传输能量的窗口。 还提供了一种控制生化分析仪内部温度的方法。