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公开(公告)号：US20160081977A1
公开(公告)日：2016-03-24
申请号：US14761474
申请日：2014-01-15
Applicant: SYMRISE AG
Inventor： Elke Köck , Jakob Ley , Veronika Somoza , Kathrin Liszt , Sabine Widder
IPC: A61K31/365 , A61K47/22 , A61K31/353 , A61K31/341 , A23L1/22 , A23L1/30
CPC classification number: A61K31/365 , A23F3/405 , A23F5/465 , A23L2/52 , A23L27/86 , A23L33/10 , A23V2002/00 , A61K9/0056 , A61K9/0058 , A61K9/0095 , A61K9/19 , A61K9/4875 , A61K31/341 , A61K31/353 , A61K47/22 , G01N33/5044
Abstract: Pharmaceutical preparations are proposed, comprising bitter-masking acting substances for reducing and/or inhibiting gastric acid secretion induced by food constituents.
Abstract translation: 提出了药物制剂，其包含用于减少和/或抑制由食物成分引起的胃酸分泌的苦味作用物质。
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公开(公告)号：US20150259319A1
公开(公告)日：2015-09-17
申请号：US14644477
申请日：2015-03-11
Applicant: Symrise AG
Inventor： Jakob Ley , Katja Obst , Katharina Reichelt , Veronika Somoza , Barbara Rohm
IPC: C07D317/60 , A23L1/30 , A23L1/29
CPC classification number: C07D317/60 , A23G1/32 , A23G1/42 , A23G3/36 , A23G3/364 , A23L33/10 , A23L33/30 , A23V2002/00 , A61K31/36 , A61K31/4525
Abstract: What are proposed are primarily aromatic alkenoic acid derivatives of the formula I for use in a therapeutic method as (a) means for reducing appetite and/or (b) means for causing a feeling of satiation and/or as (c) means for reducing energy intake and/or as (d) mood enhancers, and the non-therapeutic use of the aromatic alkenoic acid derivatives of formula I as (a) means for reducing appetite and/or (b) means for causing a feeling of satiation and/or as (c) means for reducing energy intake and/or as (d) mood enhancers.
Abstract translation: 所提出的主要是式I的芳族链烯酸衍生物，用于治疗方法，如（a）减少食欲的手段和/或（b）引起饱腹感的手段和/或作为（c）减少的手段 能量摄入和/或作为（d）情绪增强剂，并且式I的芳族链烯酸衍生物的非治疗用途为（a）用于减少食欲的手段和/或（b）引起饱腹感和/ 或（c）减少能量摄入和/或作为（d）情绪增强剂的方法。
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公开(公告)号：US12262725B2
公开(公告)日：2025-04-01
申请号：US15771944
申请日：2015-11-14
Applicant: SYMRISE AG
Inventor： Johannes Kiefl , Susanne Paetz , Jakob Ley , Michael Backes , Joachim Hans
Abstract: The present invention describes a food product comprising (a) juice, marrow, flesh or peels or other components of at least one citrus fruit, (b) at least one neoflavonoid as well as optionally (c) further flavoring agents or flavor preparations, providing that the component (b) is present in a sufficient amount to improve the sour and/or bitter taste of the component (a).
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公开(公告)号：US11485930B2
公开(公告)日：2022-11-01
申请号：US16615863
申请日：2017-06-01
Applicant: SYMRISE AG
Inventor： Michael Backes , Jekaterina Ongouta , Jakob Ley , Tobias Vössing , Volkmar Koppe , Jens Koch
Abstract: The present invention primarily relates to a method for producing an aromatic blend comprising unsaturated dienals. The invention further relates to aromatic blends obtained or obtainable by a method according to the invention and compositions or semi-finished products for producing said compositions, comprising aromatic blends according to the invention. A further aspect of the present invention relates to the use of an aromatic blend according to the invention for aromatizing a composition, preferably a composition serving for food or pleasure, or a semi-finished product for producing such a composition.
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公开(公告)号：US10736829B2
公开(公告)日：2020-08-11
申请号：US15764525
申请日：2015-09-30
Applicant: SYMRISE AG
Inventor： Joachim Hans , Jakob Ley , Kathrin Langer , Susanne Paetz
Abstract: The present invention relates primarily to the use of certain hydroxybenzoic acid amides or the salts or mixtures thereof for masking an unpleasant taste impression, preferably of a bitter, adstringent, dusty, dry, floury, rancid, metallic and/or cardboard taste or aftertaste, of one or more unpleasant-tasting peptides or of certain amino acid mixtures. The invention further relates to a corresponding method for masking unpleasant taste impressions and to novel preparations.
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Patent Agency Ranking
公开(公告)号：US10435673B2
公开(公告)日：2019-10-08
申请号：US15514120
申请日：2015-09-27
Applicant: Symrise AG
Inventor： Ludger Wessjohann , Anne-Kathrin Bauer , Jakob Ley , Torsten Geissler , Katrin Geissler
Abstract: A method is proposed for producing flavonoids, comprising the steps: (a) providing of a transgenic microorganism, containing (i) a first nucleic acid section (A), comprising or consisting of a gene coding for a CYP450 oxidase, (ii) a second nucleic acid section (B), comprising or consisting of a gene coding for a plant O-methyltransferase, and (b) adding of one or more flavanones to the transgenic microorganism, (c) the conversion of the substrate flavanones by the transgenic microorganism to the corresponding flavonoids, and optionally (d) isolating and purifying of the final products.
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公开(公告)号：US20190021378A1
公开(公告)日：2019-01-24
申请号：US15755599
申请日：2015-09-01
Applicant: SYMRISE AG
Inventor： Johannes KIEFL , Susanne Paetz , Jakob Ley , Gerhard Krammer , Thomas Riess , Kathrin Langer , Gunter Kindel , Morine Verqohlt
CPC classification number: A23L19/07 , A23L27/13 , A23L27/2052 , A23L27/84 , A23L27/86 , A23V2002/00 , A23V2200/16
Abstract: The invention relates to a foodstuff, containing: a) juice, pith, flesh, skins; or other constituents of at least one citrus fruit, b) at least one 4-hydroxyflavanone of the formula (I), in which R1 represents hydrogen or a hydroxy group a or methoxy group and the carbon atom at the position (C2) designated by * is present in a (2S) or a (2R) configuration or in any mixture of the two configurations, and also, if applicable, c) further flavorings or flavoring preparations, with the proviso that the constituent (b) is present in a sufficient quantity to improve the acidic and/or bitter taste of the constituent (a).
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公开(公告)号：US10028967B2
公开(公告)日：2018-07-24
申请号：US15324457
申请日：2015-06-27
Applicant: Symrise AG
Inventor： Donna Rosa , Jakob Ley , Gerhard Krammer , Deborah Kennison
IPC: A61K31/616 , A61K31/485 , A61K31/192 , A61K31/167 , A61K31/137 , A61K9/00 , A61K47/10 , A61K31/09 , A23L33/10
Abstract: Suggested is a medicament which is particularly useful for preventing, curing or abating of cough and inflammations of the respiratory system, comprising or consisting of active pharmaceutical ingredients and 1,3-propandiol.
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公开(公告)号：US20180135029A1
公开(公告)日：2018-05-17
申请号：US15514120
申请日：2015-09-27
Applicant: Symrise AG
Inventor： Ludger Wessjohann , Anne-Kathrin Bauer , Jakob Ley , Torsten Geissier , Katrin Geissler
CPC classification number: C12N9/1007 , C12N9/0071 , C12N15/64 , C12P17/06 , C12Y114/14001 , C12Y201/01
Abstract: A method is proposed for producing flavonoids, comprising the steps: (a) providing of a transgenic microorganism, containing (i) a first nucleic acid section (A), comprising or consisting of a gene coding for a CYP450 oxidase, (ii) a second nucleic acid section (B), comprising or consisting of a gene coding for a plant O-methyltransferase, and (b) adding of one or more flavanones to the transgenic microorganism, (c) the conversion of the substrate flavanones by the transgenic microorganism to the corresponding flavonoids, and optionally (d) isolating and purifying of the final products.
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公开(公告)号：US20170196898A1
公开(公告)日：2017-07-13
申请号：US15324457
申请日：2015-06-27
Applicant: Symrise AG
Inventor： Donna Rosa , Jakob Ley , Gerhard Krammer , Deborah Kennison
IPC: A61K31/616 , A61K47/10 , A61K31/485 , A23L33/10 , A61K31/167 , A61K31/137 , A61K31/09 , A61K9/00 , A61K31/192
CPC classification number: A61K31/616 , A23L33/10 , A23V2002/00 , A61K8/345 , A61K8/36 , A61K8/37 , A61K8/41 , A61K8/42 , A61K8/4926 , A61K8/4946 , A61K9/0056 , A61K9/0058 , A61K9/0095 , A61K31/09 , A61K31/137 , A61K31/167 , A61K31/192 , A61K31/485 , A61K47/10 , A61Q11/00 , A61K2300/00
Abstract: Suggested is a medicament which is particularly useful for preventing, curing or abating of cough and inflammations of the respiratory system, comprising or consisting of active pharmaceutical ingredients and 1,3-propandiol.
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