公开(公告)号：US20090181852A1

公开(公告)日：2009-07-16

申请号：US12084895

申请日：2006-11-15

Applicant: Alan George Clark ,  Mohamed Mutwahar Gani ,  Steven Howell

Inventor： Alan George Clark ,  Mohamed Mutwahar Gani ,  Steven Howell

IPC: C04B30/00 ,  C40B60/10

CPC classification number: G01N33/92

Abstract: Assays can determine multiple analytes in a sample, such as a biological marker and a drug-related compound.

Abstract translation: 测定可以确定样品中的多种分析物，如生物标记物和药物相关化合物。

公开(公告)号：US07358096B1

公开(公告)日：2008-04-15

申请号：US10129012

申请日：2000-11-22

Applicant: Steven Daryl Grant ,  Steven Howell ,  Stephen Wilson

Inventor： Steven Daryl Grant ,  Steven Howell ,  Stephen Wilson

IPC: G01N33/543

CPC classification number: C07K16/26 ,  C07K17/06 ,  C07K2317/22 ,  G01N33/54353 ,  Y10S435/824 ,  Y10S436/824

Abstract: The immobilization of proteins at solid surfaces facilitated by incorporation of a polypeptide segment which is capable of adopting a folded structure is described. Materials comprising proteins so immobilized and uses thereof are also described.

Abstract translation: 描述了通过掺入能够采用折叠结构的多肽片段促进固体表面蛋白质的固定化。 还描述了包含如此固定的蛋白质的材料及其用途。

公开(公告)号：US07305896B2

公开(公告)日：2007-12-11

申请号：US10930717

申请日：2004-08-31

Applicant: Steven Howell ,  James Troke

Inventor： Steven Howell ,  James Troke

IPC: G01N1/12 ,  A61B5/15

CPC classification number: G01N1/12 ,  A61B5/150022 ,  A61B5/150343

Abstract: A device for receiving a sample of liquid, such as a sample of bodily liquid which is to be subjected to further analysis, may include a body having at least a major surface and a minor surface. A sample-receiving chamber may be located in the body and may have an inlet end which opens into the major and minor surfaces of the body. A conduit may be located in the body, extending from the outlet end of the chamber, and may be arranged so as to allow the liquid to pass from the outlet end into the conduit by capillary action.

Abstract translation: 用于接收液体样品（例如待进一步分析的体液样品）的装置可以包括具有至少主表面和次表面的主体。 样品接收室可以位于主体中，并且可以具有通向主体的主表面和次表面的入口端。 导管可以位于主体中，从腔室的出口端延伸，并且可以被布置成允许液体通过毛细管作用从出口端通过导管。

公开(公告)号：US20070003444A1

公开(公告)日：2007-01-04

申请号：US11436412

申请日：2006-05-18

Applicant: Steven Howell ,  Aman Khan ,  Paul Perry ,  Andrew Phelan ,  James Troke

Inventor： Steven Howell ,  Aman Khan ,  Paul Perry ,  Andrew Phelan ,  James Troke

IPC: B01L3/00

CPC classification number: B01L3/502707 ,  B01L2300/0887 ,  B01L2300/161

Abstract: A microfluidic device is made up from at least four laminae, the laminae including two outer laminae and at least two further laminae disposed between the outer laminae and defining a microfluidic pathway. Inner surfaces of the outer laminae define the upper and lower surfaces of a fluid pathway, one of said further laminae defining at least a first fluidic element, and at least a second of said further laminae defining at least a second fluidic element, wherein the first and second fluidic elements are fluidically coupled.

Abstract translation: 微流体装置由至少四个薄片组成，薄片包括两个外薄片和至少两个另外的薄片，其设置在外层之间并限定微流体通路。 外层的内表面限定了流体通道的上表面和下表面，所述另外的层之一限定了至少第一流体元件，并且至少限定了至少第二流体元件的第二流体元件，其中第一流体元件 并且第二流体元件流体耦合。

公开(公告)号：US20050099836A1

公开(公告)日：2005-05-12

申请号：US10998483

申请日：2004-11-29

Applicant: Luan Tran ,  Stephen Porter ,  Scot Graham ,  Steven Howell

Inventor： Luan Tran ,  Stephen Porter ,  Scot Graham ,  Steven Howell

IPC: G11C7/12 ,  G11C7/18 ,  G11C11/4097 ,  G11C11/24 ,  G11C5/06

CPC classification number: G11C7/02 ,  G11C7/12 ,  G11C7/18 ,  G11C11/401 ,  G11C11/4097 ,  G11C29/816 ,  G11C2207/002 ,  G11C2207/005 ,  Y10S257/906

Abstract: A memory device includes isolation devices located between memory cells. A plurality of isolation lines connects the isolation devices to a positive voltage during normal operations but still keeps the isolation devices in the off state to provide isolation between the memory cells. A current control circuit is placed between the isolation lines and a power node for reducing a current flowing between the isolation lines and the power node in case a deflect occurs at any one of isolation devices.

Abstract translation: 存储器件包括位于存储器单元之间的隔离器件。 多个隔离线在正常操作期间将隔离装置连接到正电压，但是仍然使隔离装置保持在关闭状态以提供存储单元之间的隔离。 在隔离线路和电源节点之间放置电流控制电路，用于在任何一个隔离装置发生偏转的情况下减少在隔离线路与功率节点之间流动的电流。

公开(公告)号：US09063132B2

公开(公告)日：2015-06-23

申请号：US12753592

申请日：2010-04-02

Applicant: John William Dilleen ,  Phillip Lowe ,  Ruth Polwart ,  Jennifer Hay ,  Claus Marquordt ,  Steven Alexander Keatch ,  Steven Howell ,  Alan Thomson

Inventor： John William Dilleen ,  Phillip Lowe ,  Ruth Polwart ,  Jennifer Hay ,  Claus Marquordt ,  Steven Alexander Keatch ,  Steven Howell ,  Alan Thomson

IPC: C12Q1/28 ,  C12Q1/00 ,  G01N33/00 ,  G01N33/53 ,  G01N33/543 ,  B01L3/00 ,  G01N1/00 ,  G01N27/26

CPC classification number: G01N33/54326 ,  B01L3/502715 ,  B01L3/502761 ,  B01L3/502769 ,  B01L2300/0645 ,  B01L2300/0816 ,  B01L2300/0887 ,  B01L2400/043 ,  B01L2400/0688 ,  G01N33/54366

Abstract: An assay method and device can perform at least one (e.g., at least two) assays on a single aliquot of a sample liquid. The device can mix a sample liquid with assay reagents including magnetically susceptible particles. The device is configured to create a sample liquid-air interface with the sample liquid. The magnetically susceptible particles can be located (via an applied magnetic field) at the liquid-air interface when a second liquid contacts the interface to form a liquid-liquid interface. The magnetic particles travel across the liquid:liquid interface to the second liquid. The magnetically susceptible particles are configured to transport an analyte across the interface into the second liquid. An assay for the analyte is performed in the second liquid. An assay for another analyte can also be performed in the sample liquid.

Abstract translation: 测定方法和装置可以在样品液体的单个等分试样上进行至少一个（例如，至少两个）测定。 该装置可以将样品液体与包含磁敏感颗粒的测定试剂混合。 该装置被配置为产生与样品液体的样品液 - 空界面。 当第二液体接触界面以形成液 - 液界面时，磁敏感颗粒可以在液 - 空界面处（通过施加的磁场）定位。 磁性颗粒穿过液体：与第二液体的液体界面。 磁敏感颗粒被配置成将分析物通过界面输送到第二液体中。 在第二液体中进行分析物的测定。 也可以在样品液体中进行另一分析物的测定。

公开(公告)号：US20120172093A1

公开(公告)日：2012-07-05

申请号：US13416763

申请日：2012-03-09

Applicant: David A. Cathey, JR. ,  Steven Howell ,  James Cathey

Inventor： David A. Cathey, JR. ,  Steven Howell ,  James Cathey

IPC: H04W88/02

CPC classification number: H04M1/0272 ,  G03B21/00 ,  G03B21/005 ,  G03B29/00 ,  H04M1/02 ,  H04M1/0202 ,  H04M1/0279 ,  H04M1/03 ,  H04M1/57 ,  H04N5/74

Abstract: An apparatus may include a device and an image projection system configured to form an image on a surface viewable by a user. The image projection circuit may be configured to receive signals from the device, generate a pattern representative of data, process the pattern into a mirror image of the image, and project the mirror image from the device. The image projection system may include an electro optic system for generating the pattern, and an optics system for projecting the mirror image onto the surface.A method for projecting data may include providing the device with the image, and providing the image to the surface with the image projection system. The method may also include manipulating the device and/or a body part to locate and focus the image, sensing an orientation of the device, and orienting the image based, at least in part, on the sensing step.

Abstract translation: 设备可以包括被配置为在用户可观看的表面上形成图像的设备和图像投影系统。 图像投影电路可以被配置为从设备接收信号，生成表示数据的图案，将图案处理成图像的镜像，并从设备投影镜像。 图像投影系统可以包括用于产生图案的电光学系统和用于将镜像投影到表面上的光学系统。 用于投影数据的方法可以包括向设备提供图像，以及将图像提供给具有图像投影系统的表面。 该方法还可以包括操纵装置和/或身体部分以至少部分地基于感测步骤来定位和聚焦图像，感测装置的取向和定向图像。

公开(公告)号：US20110053289A1

公开(公告)日：2011-03-03

申请号：US12294818

申请日：2007-03-29

Applicant: Phillip Lowe ,  Steven Alexander Keatch ,  Steven Howell ,  Claus Marquordt ,  Ruth Polwart ,  Alan Kenneth Thomson

Inventor： Phillip Lowe ,  Steven Alexander Keatch ,  Steven Howell ,  Claus Marquordt ,  Ruth Polwart ,  Alan Kenneth Thomson

IPC: G01N33/53 ,  G01N27/26

CPC classification number: G01N33/558 ,  B01L3/5027 ,  B01L3/502715 ,  B01L3/502761 ,  B01L3/502769 ,  B01L9/527 ,  B01L2200/0621 ,  B01L2200/0668 ,  B01L2300/0636 ,  B01L2300/0645 ,  B01L2300/0672 ,  B01L2300/0816 ,  B01L2300/0867 ,  B01L2300/0887 ,  B01L2400/0406 ,  B01L2400/0683 ,  B01L2400/0688 ,  B01L2400/086 ,  G01N33/54326 ,  G01N33/54366 ,  G01N35/0098

Abstract: An assay method and device can perform at least one (e.g., at least two) assays on a single aliquot of a sample liquid. The device can mix a sample liquid with assay reagents including magnetically susceptible particles. The device is configured to create a sample liquid-air interface with the sample liquid. The magnetically susceptible particles can be located (via an applied magnetic field) at the liquid-air interface when a second liquid contacts the interface to form a liquid-liquid interface. The magnetic particles travel across the liquid-liquid interface to the second liquid. The magnetically susceptible particles are configured to trans-port an analyte across the interface into the second liquid. An assay for the analyte is performed in the second liquid. An assay for another analyte can also be performed in the sample liquid.

Abstract translation: 测定方法和装置可以在样品液体的单个等分试样上进行至少一个（例如，至少两个）测定。 该装置可以将样品液体与包含磁敏感颗粒的测定试剂混合。 该装置被配置为产生与样品液体的样品液 - 空界面。 当第二液体接触界面以形成液 - 液界面时，磁敏感颗粒可以在液 - 空界面处（通过施加的磁场）定位。 磁性颗粒穿过液体 - 液体界面移动到第二液体。 磁敏感颗粒被配置成将分析物跨越界面转运到第二液体中。 在第二液体中进行分析物的测定。 也可以在样品液体中进行另一分析物的测定。

公开(公告)号：US20090130771A1

公开(公告)日：2009-05-21

申请号：US11988595

申请日：2006-07-19

Applicant: Oliver William Hardwicke Davies ,  David Kinniburgh Lang ,  John William Dilleen ,  Phillip Lowe ,  Steven Howell ,  Christopher John Slevin

Inventor： Oliver William Hardwicke Davies ,  David Kinniburgh Lang ,  John William Dilleen ,  Phillip Lowe ,  Steven Howell ,  Christopher John Slevin

IPC: G01N27/00 ,  B01J19/00 ,  G01N21/00 ,  C12M1/00

CPC classification number: G01N33/54326

Abstract: An assay device includes a first reagent including a magnetic particle and a second reagent including detectable component. The first and second reagent can each independently bind to an analyte in a sample. Applying a magnetic field can selectively concentrate the detectable component in a detection zone, where a detectable change ca be measured and related to the amount of analyte in the sample.

Abstract translation: 测定装置包括包含磁性颗粒的第一试剂和包含可检测组分的第二试剂。 第一和第二试剂可以各自独立地结合样品中的分析物。 应用磁场可以将可检测组分选择性地浓缩在检测区域中，其中可测量可检测的变化并与样品中分析物的量相关。

公开(公告)号：US20060172767A1

公开(公告)日：2006-08-03

申请号：US11049458

申请日：2005-02-02

Applicant: David Cathey ,  Steven Howell ,  James Cathey

Inventor： David Cathey ,  Steven Howell ,  James Cathey

IPC: H04M11/00

CPC classification number: H04M1/0272 ,  G03B21/00 ,  G03B21/005 ,  G03B29/00 ,  H04M1/02 ,  H04M1/0202 ,  H04M1/0279 ,  H04M1/03 ,  H04M1/57 ,  H04N5/74

Abstract: A portable phone includes a handset and a data projection system configured to form a visual image of data, such as caller waiting ID data, on a viewing surface viewable by a user during a two way conversation. The handset also includes a speaker, a microphone, conventional phone circuitry and a keyboard. The data projection system is configured to receive signals from the phone circuitry, to generate a pattern representative of the data, to process the pattern into a mirror image of the visual image, and to project the mirror image from a bottom end surface of the handset. The projection system includes an electro optic system for generating the pattern, and an optics system for projecting the mirror image onto the viewing surface. A method for projecting data in a portable phone includes the steps of: providing the handset with the data projection system, conducting a two way conversation with the handset held against the head of the user, and forming the visual image on the viewing surface during the two way conversation with the handset held against the head. The method can also include the steps of manipulating the handset and a body part to locate and focus the visual image, sensing an orientation of the handset during the two way conversation, and orienting the visual image as a function of the sensing step.