公开(公告)号：US20170159092A1

公开(公告)日：2017-06-08

申请号：US15368092

申请日：2016-12-02

Applicant: INVISTA North America S.a.r.l.

Inventor： Alexander Van Eck CONRADIE ,  Adriana Leonora BOTES ,  Jonathan KENNEDY ,  Nadia Fatma KADI

IPC: C12P19/32 ,  C12N9/02 ,  C08G69/02 ,  C12P7/48 ,  C12P7/42 ,  C12P7/18 ,  C12N9/10 ,  C12P13/00

CPC classification number: C12P19/32 ,  C08G69/02 ,  C12N9/0008 ,  C12N9/1029 ,  C12N9/1096 ,  C12N9/13 ,  C12P7/18 ,  C12P7/42 ,  C12P7/48 ,  C12P11/00 ,  C12P13/00 ,  C12P13/001 ,  C12P21/00 ,  C12Y102/99006 ,  C12Y203/01 ,  C12Y203/01016 ,  C12Y203/01041 ,  C12Y203/01174 ,  C12Y203/01179 ,  C12Y203/0118 ,  C12Y206/01018 ,  C12Y208/03

Abstract: This document describes biochemical pathways for producing 7-aminoheptanoic acid using a β-ketoacyl synthase or a β-ketothiolase to form an N-acetyl-5-amino-3-oxopentanoyl-CoA intermediate. 7-aminoheptanoic acid can be enzymatically converted to pimelic acid, 7-hydroxyheptanoic acid, heptamethylenediamine or 1,7-heptanediol or corresponding salts thereof. This document also describes recombinant microorganisms producing 7-aminoheptanoic acid as well as pimelic acid, 7-hydroxyheptanoic acid, heptamethylenediamine and 1,7-heptanediol or corresponding salts thereof.

公开(公告)号：US09617572B2

公开(公告)日：2017-04-11

申请号：US14138827

申请日：2013-12-23

Applicant: INVISTA North America S.á r.l.

Inventor： Adriana Leonora Botes ,  Alex Van Eck Conradie ,  Changlin Chen ,  Paul S. Pearlman

IPC: C12P7/44 ,  C12P13/02 ,  C12P7/24 ,  C08G69/28 ,  C12P13/00 ,  C12P7/18 ,  C12P7/42 ,  C12N15/52

CPC classification number: C12P7/44 ,  C12N9/0006 ,  C12N9/0008 ,  C12N9/1096 ,  C12N9/13 ,  C12N9/16 ,  C12N9/80 ,  C12N9/93 ,  C12N15/52 ,  C12P7/18 ,  C12P7/42 ,  C12P13/001 ,  C12P13/005 ,  C12Y101/01258 ,  C12Y102/01063 ,  C12Y206/01 ,  C12Y208/03012 ,  C12Y301/02 ,  C12Y305/01062 ,  C12Y602/01005

Abstract: This document describes biochemical pathways for producing pimelic acid, 7-aminoheptanoate, 7-hydroxyheptanoate, heptamethylenediamine, or 1,7-heptanediol by forming two terminal functional groups, comprised of carboxyl, amine or hydroxyl group, in a C7 aliphatic backbone substrate produced from chorismate or benzoate. These pathways, metabolic engineering and cultivation strategies described herein rely on the anaerobic benzoyl-CoA degradation pathway enzymes.

公开(公告)号：US09586892B2

公开(公告)日：2017-03-07

申请号：US14649634

申请日：2013-12-05

Applicant: INVISTA NORTH AMERICA S.A R.L.

Inventor： Sudhir N. V. K. Aki ,  William J. Tenn, III ,  Thomas E. Vos

IPC: C07C253/30

CPC classification number: C07C253/30 ,  C07C255/07

Abstract: Pentenenitrile oligomers formed in a process for isomerizing cis-2-pentenenitrile to 3-pentenenitrile are minimized in the presence of an aluminum oxide catalyst. The process comprises providing an aluminum oxide catalyst having an alkali metal and/or alkaline earth metal and/or iron content, measured in the form of alkali metal oxide and/or alkaline earth metal oxide and/or iron oxide, respectively of less than 5000 ppm by weight.

Abstract translation: 在氧化铝催化剂存在下使在顺式-2-戊烯腈异构化为3-戊烯腈的方法中形成的戊烯腈低聚物最小化。 该方法包括提供具有碱金属和/或碱土金属和/或铁含量的氧化铝催化剂，其以碱金属氧化物和/或碱土金属氧化物和/或氧化铁的形式分别测量为小于5000 重量ppm。

公开(公告)号：US09580731B2

公开(公告)日：2017-02-28

申请号：US14138971

申请日：2013-12-23

Applicant: INVISTA North America S.á r.l.

Inventor： Adriana Leonora Botes ,  Alex Van Eck Conradie ,  Changlin Chen ,  Paul S. Pearlman

IPC: C12P13/00 ,  C12P7/18 ,  C12P7/42 ,  C12P7/44 ,  C12N15/52

CPC classification number: C12N15/52 ,  C12N9/0006 ,  C12N9/0008 ,  C12N9/1025 ,  C12N9/1029 ,  C12N9/1096 ,  C12N9/1288 ,  C12N9/16 ,  C12N9/80 ,  C12N9/88 ,  C12N9/93 ,  C12P7/18 ,  C12P7/24 ,  C12P7/42 ,  C12P7/44 ,  C12P13/001 ,  C12P13/005 ,  C12Y101/01 ,  C12Y101/01085 ,  C12Y101/01087 ,  C12Y101/01258 ,  C12Y101/01286 ,  C12Y102/01 ,  C12Y102/01003 ,  C12Y102/0101 ,  C12Y102/99006 ,  C12Y203/01032 ,  C12Y203/03013 ,  C12Y203/03014 ,  C12Y206/01 ,  C12Y207/08 ,  C12Y208/03012 ,  C12Y301/02 ,  C12Y305/01062 ,  C12Y401/01043 ,  C12Y402/01033 ,  C12Y402/01036 ,  C12Y402/01114 ,  C12Y602/01005

Abstract: This document describes biochemical pathways for producing pimelic acid, 7-aminoheptanoic acid, 7-hydroxyheptanoic acid, heptamethylenediamine or 1,7-heptanediol by forming one or two terminal functional groups, each comprised of carboxyl, amine or hydroxyl group, in a C7 aliphatic backbone substrate. These pathways, metabolic engineering and cultivation strategies described herein rely on the C1 elongation enzymes or homolog associated with coenzyme B biosynthesis.

Abstract translation: 本文件描述了通过在C7脂肪族中形成一个或两个由羧基，胺或羟基组成的末端官能团，生成庚二酸，7-氨基庚酸，7-羟基庚酸，七亚甲基二胺或1,7-庚二醇的生化途径 骨架底物。 本文描述的这些途径，代谢工程和培养策略依赖于C1延长酶或与辅酶B生物合成相关的同源物。

公开(公告)号：US09487889B2

公开(公告)日：2016-11-08

申请号：US13997831

申请日：2011-05-18

Applicant: Steven W. Smith ,  Raymond S. P. Leung

Inventor： Steven W. Smith ,  Raymond S. P. Leung

IPC: D02G3/36 ,  D02G3/32 ,  D01F8/16

CPC classification number: D02G3/36 ,  D01F8/16 ,  D02G3/32

Abstract: Disclosed herein are spandex fibers having reduced friction combined to provide a multiple end spandex package. The spandex fibers have a sheath-core cross-section with a lubricating additive is included in the sheath. A fusing additive specifically excluded to avoid coalescence among the individual filaments in the yarn. When combined in a yarn package, the multiple filaments are separable.

Abstract translation: 本文公开了具有减少的摩擦的氨纶纤维，其结合以提供多端氨纶包装。 氨纶纤维具有鞘芯横截面，其中包含润滑添加剂。 特别排除了一种熔融添加剂，以避免纱线中单根细丝之间的聚结。 当组合在纱线包装中时，多根细丝是可分离的。

公开(公告)号：US20160319067A1

公开(公告)日：2016-11-03

申请号：US15108486

申请日：2015-01-05

Applicant: INVESTA TECHNOLOGIES S.A.R.L.

Inventor： Richard P. BEATTY ,  Qun SUN

IPC: C08G63/672

CPC classification number: C08G63/672 ,  C08G65/20 ,  C08G65/2696 ,  C08G65/30 ,  C08G65/3322

Abstract: The present invention relates to a process for manufacturing copolyether ester polyol having a low oligomeric cyclic ether content, for example, less than about 2.0% by weight, from feedstock comprising polytetramethylene ether glycol having a low number average molecular weight, for example, 350 g/mol or less, and a high oligomeric cyclic ether content, for example, about 4.0% by weight or greater.

Abstract translation: 本发明涉及由具有低数均分子量的聚四亚甲基醚二醇的原料制备的共聚醚酯多元醇的方法，所述共聚醚酯多元醇的低聚环醚含量低于例如小于约2.0重量％，例如，350克 /摩尔以下，高低聚环醚含量，例如约4.0重量％以上。

公开(公告)号：US20160297746A1

公开(公告)日：2016-10-13

申请号：US15094770

申请日：2016-04-08

Applicant: INVISTA NORTH AMERICA S.a.r.l.

Inventor： Gary Smith ,  Gregory S Kirby ,  Paul Pearlman

IPC: C07C227/40 ,  C07C213/10 ,  C07C209/86

CPC classification number: B01D15/185 ,  B01D15/1892 ,  C07C209/82 ,  C07C209/86 ,  C07C211/09 ,  C07C213/10 ,  C07C227/38 ,  C07C227/40 ,  C12P13/001 ,  C12P13/005 ,  C07C211/12 ,  C07C229/08

Abstract: The present disclosure relates to methods for separating at least one amine chosen from diamines and omega-aminoacids from a feed mixture using a simulated moving bed (SMB) adsorptive technology.

Abstract translation: 本公开涉及使用模拟移动床（SMB）吸附技术从进料混合物中分离选自二胺和ω-氨基酸的至少一种胺的方法。

公开(公告)号：US09435059B2

公开(公告)日：2016-09-06

申请号：US13124438

申请日：2009-10-19

Applicant: Steven W. Smith ,  Hong Liu ,  Willem Bakker ,  Gregory P. Weeks ,  Juan Cera

Inventor： Steven W. Smith ,  Hong Liu ,  Willem Bakker ,  Gregory P. Weeks ,  Juan Cera

IPC: D04B1/18 ,  D01F1/10 ,  D01F6/70 ,  D01F8/16 ,  D02G3/32 ,  D03D15/08 ,  D04B1/16

CPC classification number: D04B1/18 ,  D01F1/10 ,  D01F6/70 ,  D01F8/16 ,  D02G3/326 ,  D03D15/08 ,  D04B1/16 ,  D10B2401/041

Abstract: Included are multiple component elastic fibers prepared by a solution-spinning process such as dry spinning or wet spinner of spandex fibers including polyurethaneurea and polyurethane compositions. These fibers have a cross-section including at least two separate regions with definable boundaries wherein at least one region defined by the boundaries of the cross-section includes a polyurethaneurea or polyurethane composition. One region of the fiber includes a fusibility improvement additive to enhance adhesion to itself or to a substrate.

Abstract translation: 包括通过溶液纺丝方法制备的多组分弹性纤维，例如干纺丝或氨纶纤维的湿纺丝，包括聚氨酯脲和聚氨酯组合物。 这些纤维具有横截面，其包括具有可限定边界的至少两个分开的区域，其中由横截面的边界限定的至少一个区域包括聚氨酯脲或聚氨酯组合物。 纤维的一个区域包括可熔融性改进添加剂以增强对其自身或底物的粘合性。

公开(公告)号：US20160251645A1

公开(公告)日：2016-09-01

申请号：US15056026

申请日：2016-02-29

Applicant: INVISTA North America S.a.r.l.

Inventor： ADRIANA L. BOTES ,  Nadia Kadi ,  Mihai Luchian Azoitei ,  Yih-En A. Ban ,  Daniela Grabs-Röthlisberger ,  Alexander Pisarchik ,  Alexandre Zanghellini ,  Eric Althoff

IPC: C12N9/88 ,  C07K16/40 ,  G01N33/573 ,  C12P5/00 ,  C08F36/06 ,  C07C11/18 ,  C07C11/21 ,  C08F36/08 ,  C08F36/22 ,  C12P5/02 ,  C07C11/167

Abstract: The present disclosure provides novel polypeptides with 3-buten-2-ol dehydratase activity, polypeptides with catalytic activity in the conversion of 3-methyl-3-buten-2-ol to isoprene, and crystal structure data for one of such polypeptides. Methods of making and using the polypeptides and their related crystal structure data are also provided.

公开(公告)号：US09422580B2

公开(公告)日：2016-08-23

申请号：US13916156

申请日：2013-06-12

Applicant: INVISTA North America S.á r.l.

Inventor： Paul S. Pearlman ,  Changlin Chen ,  Adriana Leonara Botes ,  Alex Van Eck Conradie

IPC: C12N9/88 ,  C12P5/02 ,  C12N9/02

CPC classification number: C12P5/026 ,  C12N9/001 ,  C12N9/0071 ,  C12N9/88 ,  C12N15/52 ,  C12P5/02 ,  C12P7/16 ,  C12P7/18 ,  C12Y103/01035 ,  C12Y103/08 ,  C12Y114/11022 ,  C12Y401/01033 ,  C12Y402/01 ,  C12Y402/01127 ,  C12Y402/03027 ,  Y02E50/10 ,  Y02E50/343 ,  Y02P20/52

Abstract: This document describes biochemical pathways for producing butadiene by forming two vinyl groups in a butadiene synthesis substrate. These pathways described herein rely on enzymes such as mevalonate diphosphate decarboxylase, isoprene synthase, and dehydratases for the final enzymatic step.