公开(公告)号：US09757041B2

公开(公告)日：2017-09-12

申请号：US13554483

申请日：2012-07-20

Applicant: Gregory Zlatko Grudic ,  Steven Lee Moulton ,  Isobel Jane Mulligan

Inventor： Gregory Zlatko Grudic ,  Steven Lee Moulton ,  Isobel Jane Mulligan

IPC: A61B5/0205 ,  A61B5/02 ,  A61B5/021 ,  A61B5/00 ,  A61B5/029 ,  A61B5/0402 ,  A61B5/1455

CPC classification number: A61B5/02028 ,  A61B5/02042 ,  A61B5/021 ,  A61B5/029 ,  A61B5/0402 ,  A61B5/14551 ,  A61B5/7275 ,  G06F19/00

Abstract: Tools and techniques for estimating a probability that a patient is bleeding or has sustained intravascular volume loss (e.g., due to hemodialysis or dehydration) and/or to estimate a patient's current hemodynamic reserve index, track the patient's hemodynamic reserve index over time, and/or predict a patient's hemodynamic reserve index in the future. Tools and techniques for estimating and/or predicting a patient's dehydration state. Tools and techniques for controlling a hemodialysis machine based on the patient's estimated and/or predicted hemodynamic reserve index.

公开(公告)号：US09629964B2

公开(公告)日：2017-04-25

申请号：US13936931

申请日：2013-07-08

Applicant: Fresenius Medical Care Deutschland GmbH

Inventor： Andreas Wuepper

IPC: A61M5/50 ,  G01M3/16 ,  A61M1/36 ,  A61B5/02 ,  A61M5/158 ,  G01N27/04

CPC classification number: A61M5/5086 ,  A61B5/02042 ,  A61M1/3656 ,  A61M2005/1588 ,  A61M2205/15 ,  A61M2205/3317 ,  G01M3/16 ,  G01N27/048 ,  Y10T29/49117

Abstract: A moisture sensor for monitoring an access to a patient for a system by which, via a flexible line, a liquid is fed to and/or out from a patient, for monitoring the vascular access in extra-corporeal blood treatment or for monitoring a central venous catheter for acute dialysis, and a method of producing a moisture sensor are described. The moisture sensor has a substrate material with an electrically conductive structure having conductor paths arranged at a distance from one another and connected together across a terminating resistor. The terminating resistor is an electrically conductive film which is applied in a section of the substrate material on which are formed electrical contacting regions for connecting the terminating resistor to the conductor paths, such that an external terminating resistor is not required and the moisture sensor can be produced easily in large numbers complete with the terminating resistor.

公开(公告)号：US09592029B2

公开(公告)日：2017-03-14

申请号：US13393429

申请日：2010-06-18

Applicant: Clive Buckberry

Inventor： Clive Buckberry

IPC: A61B5/05 ,  A61B8/00 ,  A61B8/08 ,  A61M1/36 ,  A61B5/00 ,  A61B5/02 ,  A61M5/168

CPC classification number: A61B8/4227 ,  A61B5/0002 ,  A61B5/02042 ,  A61B8/0841 ,  A61B8/0891 ,  A61B8/4281 ,  A61B8/4472 ,  A61M1/3653 ,  A61M1/3656 ,  A61M1/3659 ,  A61M5/16831 ,  A61M5/16836 ,  A61M2205/13 ,  A61M2205/3375

Abstract: A monitoring device (1) is provided for monitoring the presence of a skin piercing vascular access device, for example a needle (4), the monitoring device comprising: a mount having an ultrasonic transmitter and an ultrasonic receiver therein; attachment means (3) for attaching the mount to a patient adjacent a vascular access point such that, in use, a vascular access device (4) entering the patient at the vascular access point, passes underneath a sensing section of the base; control electronics to monitor the signal received at the receiver, and wherein when the vascular access device is underneath said sensing section, ultrasound produced by said transmitter passes through the patient skin and is reflected by the patients body tissues and by the vascular access device (4), and when the vascular access device (4) is not underneath said sensing section, ultrasound produced by said transmitter passes through the patients skin and is reflected by the patients body tissue only, and wherein the control electronics detects the presence of a vascular access (4) device by performing a comparison on the received ultrasonic signal. The device (1) warns if a needle (4) becomes dislodged during a treatment.

Abstract translation: 提供监测装置（1），用于监测皮肤穿刺血管通路装置（例如针（4））的存在，所述监测装置包括：在其中具有超声波发射器和超声波接收器的安装件; 附接装置（3），用于将安装件附接到邻近血管接入点处的患者，使得在使用中，在血管接入点处进入患者的血管进入装置（4）通过基底的感测部分下方; 控制电子装置，用于监测在接收器处接收到的信号，并且其中当血管通路装置位于所述传感部分下方时，由所述发射器产生的超声波穿过患者皮肤并被患者身体组织和血管通路装置（4 ），并且当血管进入装置（4）不在所述感测部分下方时，由所述发射器产生的超声波穿过患者皮肤，并且仅由患者身体组织反射，并且其中控制电子装置检测血管通路的存在 （4）装置，通过对所接收的超声信号进行比较。 装置（1）警告在处理期间针（4）是否被移开。

公开(公告)号：US20170004620A1

公开(公告)日：2017-01-05

申请号：US15267544

申请日：2016-09-16

Applicant: OLYMPUS CORPORATION

Inventor： Makoto KITAMURA ,  Yamato KANDA

IPC: G06T7/00 ,  G06T7/40 ,  A61B5/02 ,  A61B1/00 ,  A61B1/04

CPC classification number: G06T7/0012 ,  A61B1/00009 ,  A61B1/0005 ,  A61B1/041 ,  A61B5/02042 ,  A61B5/4216 ,  A61B5/4233 ,  A61B5/4238 ,  A61B5/4255 ,  A61B2576/02 ,  G06T7/0016 ,  G06T7/73 ,  G06T7/90 ,  G06T2207/10016 ,  G06T2207/10024 ,  G06T2207/10068 ,  G06T2207/30101

Abstract: An image processing apparatus includes: a detecting unit configured to detect images of interest including regions of interest that are estimated as an object to be detected, from a group of a series of images acquired by sequentially imaging a lumen of a living body; a global similarity calculating unit configured to calculate a global similarity that is a similarity between regions including at least regions other than the regions of interest, between the images of interest different from one another; an image-of-interest group extracting unit configured to extract an image-of-interest group including identical regions of interest, in accordance with comparison between a threshold and the global similarity or a determination parameter based on the global similarity; and a representative image extracting unit configured to extract a representative image from the image-of-interest group.

Abstract translation: 一种图像处理装置，包括：检测单元，被配置为从通过对生物体的内腔顺序成像而获得的一系列图像的组中检测被估计为被检测物体的感兴趣区域的图像; 全局相似度计算单元，被配置为计算在感兴趣的图像之间的至少包括感兴趣区域之外的区域之间的相似性的全局相似性; 感兴趣图像组提取单元，被配置为根据阈值和全局相似度之间的比较或基于全局相似度的确定参数来提取包括相同感兴趣区域的感兴趣图像组; 以及代表图像提取单元，被配置为从兴趣图像组中提取代表图像。

公开(公告)号：US09488610B2

公开(公告)日：2016-11-08

申请号：US13623287

申请日：2012-09-20

Applicant: Fresenius Medical Care Deutschland GmbH

Inventor： John Heppe

IPC: B32B38/00 ,  G01N27/04 ,  D03D1/00 ,  A61M1/36 ,  D03D11/00 ,  G01M3/16 ,  D03D15/00 ,  A61B5/02

CPC classification number: G01N27/048 ,  A61B5/02042 ,  A61B2562/029 ,  A61B2562/12 ,  A61M1/3653 ,  A61M1/3656 ,  A61M1/3659 ,  A61M1/3661 ,  D03D1/0088 ,  D03D11/00 ,  D03D15/00 ,  D10B2401/16 ,  D10B2509/00 ,  G01M3/16 ,  G01M3/165

Abstract: A weaving method for producing a plurality of moisture sensors for a device for monitoring an access to a patient, in particular for monitoring the vascular access in an extracorporeal blood treatment, wherein the moisture sensors are woven. During the weaving of the moisture sensors, non-conductive warp threads, non-conductive weft threads, conductive warp threads and conductive weft threads are disposed in the textile two-dimensionally extending structure, such that spatially demarcatable structures of electrical strip conductors are created. The strip conductor structures can be produced by spatial separation or contacting of the conductive warp or weft threads. In order to be able to produce the moisture sensors cost effectively in large numbers, a plurality of individual moisture sensors are repeatedly woven each time beside one another normal to the production direction on a common woven fabric web as the web progressively advances, so that the width of the woven fabric web is occupied in the best possible way by as many moisture sensors as possible. The individual moisture sensors are separated from one another after weaving.

Abstract translation: 一种织造方法，用于制造用于监测对患者进入的装置的多个湿度传感器，特别是用于监测体外血液处理中的血管通路，其中所述水分传感器被编织。 在编织湿度传感器期间，非导电经线，非导电纬纱，导电经线和导电纬纱设置在织物二维延伸结构中，从而产生电条导体的空间可分界结构。 带状导体结构可以通过导电经纱或纬纱的空间分离或接触来制造。 为了能够大量地成本有效地生产水分传感器，随着纸幅逐渐前进，多个单独湿度传感器在普通机织织物纤维网上正常地沿着生产方向彼此重复地编织，从而使 机织织物纤维网的宽度以尽可能多的湿度传感器尽可能地被占据。 各个湿度传感器在编织后彼此分离。

公开(公告)号：US20160183840A1

公开(公告)日：2016-06-30

申请号：US14805057

申请日：2015-07-21

Applicant: The Regents of the University of California

Inventor： Boris Rubinsky ,  Cesar A. Gonzalez

IPC: A61B5/053 ,  A61B5/00

CPC classification number: A61B5/0537 ,  A61B5/02042 ,  A61B5/0205 ,  A61B5/05 ,  A61B5/053 ,  A61B5/4064 ,  A61B5/413 ,  A61B5/4244 ,  A61B5/443 ,  A61B5/4519 ,  A61B5/4869 ,  A61B5/4878 ,  A61B5/7225 ,  A61B5/7228 ,  A61B5/725 ,  A61B2562/143 ,  G01N27/026 ,  G01R33/34 ,  G01R33/36 ,  G01R33/4828 ,  G01R33/483

Abstract: A method and apparatus of determining the condition of a bulk tissue sample, by: positioning a bulk tissue sample between a pair of induction coils (or antennae); passing a spectrum of alternating current (or voltage) through a first of the induction coils (or antennae); measuring spectrum of alternating current (or voltage) produced in the second of the induction coils (or antennae); and comparing the phase shift between the spectrum of alternating currents (or voltages) in the first and second induction coils (or antennae), thereby determining the condition of the bulk tissue sample.

公开(公告)号：US09364139B2

公开(公告)日：2016-06-14

申请号：US14543154

申请日：2014-11-17

Applicant: GIVEN IMAGING LTD.

Inventor： Doron Adler ,  Ofra Zinaty ,  Daphna Levy ,  Arkady Glukhovsky

IPC: A61B5/05 ,  A61B1/04 ,  A61B1/00 ,  A61B5/00 ,  A61B5/07 ,  G06T7/00 ,  G06T7/40 ,  A61B5/02

CPC classification number: A61B1/041 ,  A61B1/00009 ,  A61B1/00045 ,  A61B5/0031 ,  A61B5/0075 ,  A61B5/0084 ,  A61B5/02042 ,  A61B5/073 ,  A61B5/742 ,  A61B5/743 ,  G06F19/00 ,  G06T7/0012 ,  G06T7/90 ,  G06T2207/10024 ,  G06T2207/10068 ,  G06T2207/30028

Abstract: A system and method for detection of calorimetric abnormalities within a body lumen includes an image receiver for receiving images from within the body lumen. Also included are a transmitter for transmitting the images to a receiver, and a processor for generating a probability indication of presence of colorimetric abnormalities on comparison of color content of the images and at least one reference value.

Abstract translation: 用于检测体腔内的量热异常的系统和方法包括用于从体腔内接收图像的图像接收器。 还包括用于将图像发送到接收器的发射器和用于在比较图像的颜色内容和至少一个参考值时生成比色异常的存在的概率指示的处理器。

公开(公告)号：US09357970B2

公开(公告)日：2016-06-07

申请号：US13977689

申请日：2011-12-30

Applicant: Joseph Floyd Clark ,  Matthew L. Flaherty ,  George Shaw ,  Opeolu Adeoye

Inventor： Joseph Floyd Clark ,  Matthew L. Flaherty ,  George Shaw ,  Opeolu Adeoye

IPC: A61B5/05 ,  A61B5/00 ,  A61B5/04 ,  A61B5/02

CPC classification number: A61B5/04008 ,  A61B5/0042 ,  A61B5/0075 ,  A61B5/02042 ,  A61B5/04001 ,  A61B5/4064 ,  A61B5/4094 ,  A61B5/4878 ,  A61B5/6803 ,  A61B5/7225 ,  A61B5/7257 ,  A61B5/7282 ,  A61B5/742 ,  A61B5/746 ,  A61B2562/0223 ,  A61B2576/026

Abstract: In one embodiment, a neurological status evaluation apparatus includes a signal generator configured to generate an electromagnetic signal at one or more frequencies, a transmitting antenna coupled to the signal generator and configure to transmit the electromagnetic signal, and a receiving antenna positioned proximate to the transmitting antenna such that an evaluation space is defined between the transmitting antenna and the receiving antenna. The biological tissue under evaluation does not contact the transmitting antenna or the receiving antenna. The receiving antenna receives a modulated electromagnetic signal after propagating through the biological tissue under evaluation. The neurological status evaluation apparatus further includes a spectrum analyzer coupled to the receiving antenna, wherein the spectrum analyzer receives and samples the modulated electromagnetic signal. A computing device is coupled to the spectrum analyzer, calculates an evaluation, and provides a neurological status indicator of the biological tissue under evaluation based on the evaluation parameter.

Abstract translation: 在一个实施例中，神经状态评估装置包括被配置为产生一个或多个频率的电磁信号的信号发生器，耦合到信号发生器并被配置为传送电磁信号的发射天线以及靠近发射 天线，使得在发射天线和接收天线之间定义评估空间。 所评估的生物组织不接触发射天线或接收天线。 接收天线在评估后通过生物组织传播后接收调制电磁信号。 神经状态评估装置还包括耦合到接收天线的频谱分析仪，其中频谱分析仪接收并采样调制的电磁信号。 计算设备耦合到频谱分析仪，计算评估，并根据评估参数提供正在评估的生物组织的神经状态指标。

公开(公告)号：US09347817B2

公开(公告)日：2016-05-24

申请号：US14629813

申请日：2015-02-24

Applicant: Surgitrac Corporation

Inventor： Richard A. Pollock ,  Mahmood S. Kassam

IPC: A61B5/02 ,  G01G17/04 ,  G01G19/414 ,  G01G21/23 ,  G01G21/28 ,  G01G19/387 ,  G06F19/00 ,  A61B19/02 ,  A61B19/00 ,  B65F1/14 ,  G01G19/40 ,  A61M1/00 ,  A61B5/20 ,  B62B3/10 ,  A61B5/00

CPC classification number: G01G19/387 ,  A61B5/0059 ,  A61B5/02042 ,  A61B5/208 ,  A61B50/13 ,  A61B50/37 ,  A61B90/90 ,  A61B90/98 ,  A61B2090/0804 ,  A61B2090/0805 ,  A61B2217/005 ,  A61B2217/007 ,  A61B2560/0437 ,  A61M1/006 ,  B62B3/106 ,  B62B2203/50 ,  B65F1/1415 ,  B65F1/1473 ,  B65F1/1607 ,  B65F2210/124 ,  B65F2210/168 ,  B65F2210/184 ,  G01G17/04 ,  G01G19/40 ,  G01G19/414 ,  G01G21/23 ,  G01G21/28 ,  G06F19/00 ,  G16H40/20

Abstract: A surgical sponge and comprehensive fluid monitoring system and method are provided. The system includes a support ring for securely supporting a container with at least one port opening for receiving surgical sponges placed into the container. A hollow spine structure includes a channel and a rod that can move in the channel. The rod transfers weight force from the support ring to a weight force sensing device. A flexure maintains the rod vertically aligned in the channel with a gap separating the length of the rod from the channel walls. A processor receives an information signal indicative of at least one of urine outflow, suction fluid outflow, irrigation fluid intake; and intravenous fluid intake, of a surgical patient. The processor accumulates a total amount of estimated net fluid volume loss for the patient from the surgical sponge, and from other measured fluid outflow and intake.

Abstract translation: 提供手术海绵和综合液体监测系统和方法。 该系统包括用于牢固地支撑具有至少一个端口开口的容器的支撑环，用于接收放置在容器中的手术海绵。 中空的脊柱结构包括可以在通道中移动的通道和杆。 杆将重力从支撑环传递到重力感测装置。 弯曲部将杆保持在通道中垂直对准，并具有将杆的长度与通道壁分开的间隙。 处理器接收指示尿液流出，抽吸流体流出，冲洗液摄入中的至少一种的信息信号; 和静脉内液体摄入。 处理器累积了来自手术海绵的患者和来自其他测量的流体流出物和摄入量的估计的净流体体积损失的总量。

公开(公告)号：US20160113519A1

公开(公告)日：2016-04-28

申请号：US14805258

申请日：2015-07-21

Applicant: Sumeet Vadera

Inventor： Sumeet Vadera

IPC: A61B5/02 ,  A61B10/02

CPC classification number: A61B5/02042 ,  A61B10/0233 ,  A61B2505/05

Abstract: A biopsy needle surrounded by a peel away sheath chemically impregnated with a blood detection composition enabling a user (e.g., a surgeon) to accurately and timely determine the existence of a blood pooling or hematoma when passing an implantable (e.g., deep brain stimulation probes) or non-implantable (e.g., biopsy needle) device into a region of the subject's body (e.g., a brain) to gather tissue for further analysis. A biopsy needle may be provided wherein the needle is tightly surrounded by a peel-away sheath that is chemically impregnated with a blood detection composition. The surgeon may insert the biopsy needle into the subject and peel away the chemically impregnated sheath in order to assess whether or not a blood pooling or hematoma exists, and act immediately to address the blood pooling or hematoma.

Abstract translation: 用剥离鞘围绕的活检针，其化学浸渍有血液检测组合物，使得使用者（例如，外科医生）能够在通过可植入（例如深部脑刺激探针）时准确和及时地确定血液聚集或血肿的存在， 或不可植入（例如，活检针）装置进入受试者的身体（例如，脑）的区域以收集组织用于进一步分析。 可以提供活检针，其中针被用血液检测组合物化学浸渍的剥离鞘紧密地包围。 外科医生可以将活检针插入受试者并剥离化学浸渍的鞘，以评估是否存在血液汇集或血肿，并且立即行动以解决血液汇集或血肿。