-
公开(公告)号：US11912894B2
公开(公告)日：2024-02-27
申请号：US16696469
申请日：2019-11-26
申请人： CORNELL UNIVERSITY
发明人： Minglin Ma , You Yong , Mingyu Qiao , Qingsheng Liu
IPC分类号： A61L31/14 , A61L15/46 , A61L29/14 , A61L17/00 , A61L31/10 , A61L29/08 , A61L15/60 , A61L29/16 , A61L17/14 , A61L31/16 , C09D5/16 , B05D3/10 , B05D3/06
CPC分类号： C09D5/1625 , A61L15/60 , A61L17/005 , A61L29/085 , A61L29/145 , A61L29/16 , B05D3/067 , B05D3/101 , B05D3/108 , C09D5/1662 , C09D5/1687 , B05D2201/02 , B05D2320/00
摘要： The present application discloses a method of forming a hydrogel-coated substrate, wherein the hydrogel has antifouling and antimicrobial properties. The method comprises applying an aqueous pre-hydrogel solution to a substrate, polymerizing the aqueous pre-hydrogel solution, thereby forming a coated substrate having a conformal hydrogel coating and a non-conformal hydrogel coating, contacting the coated substrate with a swelling agent, and removing the non-conformal hydrogel coating from the coated substrate, thereby leaving the conformal hydrogel coating on the substrate to form the hydrogel-coated substrate. The aqueous pre-hydrogel solution comprises a monomer with antimicrobial activity, a monomer with antifouling activity, and either a polymer, oligomer, or macromer which, when polymerized together, form a hydrogel. Also disclosed is a coated substrate and a hydrogel coating.
-
公开(公告)号：US20240058509A1
公开(公告)日：2024-02-22
申请号：US18499995
申请日：2023-11-01
CPC分类号： A61L29/085 , A61F2/2433 , A61L29/06 , A61L29/143 , A61M2025/1075
摘要： Balloon compositions that may be used for deployment of implants within a patient's body. The balloons in examples may be utilized for dilating implants and may be coupled to a delivery catheter for an implant. In examples, the balloons may be utilized to dilate other surfaces within the patient's body.
-
公开(公告)号：US11896777B2
公开(公告)日：2024-02-13
申请号：US17409215
申请日：2021-08-23
申请人： QMAX, LLC
发明人： Robert C. Laduca
IPC分类号： A61M25/00 , A61L29/12 , A61L29/08 , A61L29/14 , B29C48/09 , B29L31/00 , B29C63/18 , B29C63/42 , B29C48/19
CPC分类号： A61M25/0023 , A61L29/085 , A61L29/12 , A61L29/14 , A61M25/0052 , A61M2025/0024 , B29C48/09 , B29C48/19 , B29C63/18 , B29C63/42 , B29L2031/7542
摘要： Methods and devices described for improved dynamic walled tubing and catheters.
-
公开(公告)号：US20240042180A1
公开(公告)日：2024-02-08
申请号：US18487987
申请日：2023-10-16
申请人： CJMI, LLC
发明人： Carmin Kalorin , Jack Slovick , Michael Weddington , Ian Udell , Laura Helton
CPC分类号： A61M25/10 , A61L29/085 , A61L29/16 , A61M25/0021 , A61M25/0017 , A61M2210/1085 , A61L2400/04 , A61M2205/587 , A61M2205/0205 , A61M2205/583 , A61M2025/1043 , A61M2205/05 , A61M25/007 , A61M25/0032 , A61M25/1011 , A61M2025/0057 , A61M2025/0056 , A61M25/0023 , A61L2/0047
摘要： Apparatus and methods for treatment of bleeding and/or microbial infection of the genitourinary tract including a catheter and an insertable and removable medicament-delivery sheath for introducing a hemostatic and/or anti-microbial substance or the like. Some embodiments further include a light-delivery sheath and/or light-delivery-and-imaging sheath having a light-propagation channel, and a source of anti-microbial and/or imaging light in one or more wavelength bands, for example UVC light and/or light in the visible violet, blue or green wavelength ranges. Some embodiments include a display for captured images, and/or a motorized sheath-movement device configured to move one or more light-output ports. Some embodiments further include a light-propagation channel built into the catheter itself (such as one or more optical fibers) for the administration of anti-microbial ultraviolet light (and/or other wavelengths of light) light along the catheter and/or at the distal end of the catheter to treat and/or prevent microbial (bacterial and/or fungal) infections.
-
公开(公告)号：US20230405294A1
公开(公告)日：2023-12-21
申请号：US18210697
申请日：2023-06-16
申请人： Tekni-Plex, Inc.
发明人： Paul McShane , Ian Kenny , Robin Van Landeghem
IPC分类号： A61M39/08 , A61L29/06 , A61L29/08 , A61L29/14 , B32B1/08 , B32B27/32 , B32B27/40 , B32B27/08 , B32B27/30
CPC分类号： A61M39/08 , A61L29/06 , A61L29/085 , A61L29/14 , B32B1/08 , B32B27/32 , B32B27/40 , B32B27/08 , B32B27/306 , A61M2207/00 , A61M25/0045
摘要： In one embodiment, a visually clear or transparent and manually flexible medical tube (10) adapted for in vivo transport of an aqueous fluid to a subject comprising an inner layer (3), a middle layer (2) and an outer layer (1),
wherein the inner layer (3) comprises a polypropylene,
the outer layer (1) comprises a thermoplastic polyurethane or a cyclic olefin copolymer, and
the middle layer (2) is selected from one or more of ethylene vinyl acetate copolymers, ethylene acrylate copolymers, ethylene-acrylate maleic anhydride terpolymers, ethylene-acrylate glycidyl methacrylate terpolymers, and maleic anhydride grafted polypropylene.-
公开(公告)号：US11819644B2
公开(公告)日：2023-11-21
申请号：US17069158
申请日：2020-10-13
申请人： CJMI, LLC
发明人： Carmin Kalorin , Jack Slovick , Michael Weddington , Ian Udell , Laura Helton
CPC分类号： A61M25/10 , A61L29/085 , A61L29/16 , A61M25/0017 , A61M25/0021 , A61L2/0047 , A61L2202/14 , A61L2400/04 , A61M25/007 , A61M25/0023 , A61M25/0032 , A61M25/1011 , A61M2025/0056 , A61M2025/0057 , A61M2025/1043 , A61M2205/0205 , A61M2205/05 , A61M2205/583 , A61M2205/587 , A61M2210/1085
摘要： Apparatus and methods for treatment of bleeding and/or microbial infection of the genitourinary tract including a catheter and an insertable and removable medicament-delivery sheath for introducing a hemostatic and/or anti-microbial substance or the like. Some embodiments further include a light-delivery sheath and/or light-delivery-and-imaging sheath having a light-propagation channel, and a source of anti-microbial and/or imaging light in one or more wavelength bands, for example UVC light and/or light in the visible violet, blue or green wavelength ranges. Some embodiments include a display for captured images, and/or a motorized sheath-movement device configured to move one or more light-output ports. Some embodiments further include a light-propagation channel built into the catheter itself (such as one or more optical fibers) for the administration of anti-microbial ultraviolet light (and/or other wavelengths of light) light along the catheter and/or at the distal end of the catheter to treat and/or prevent microbial (bacterial and/or fungal) infections.
-
公开(公告)号：US11814526B2
公开(公告)日：2023-11-14
申请号：US18079085
申请日：2022-12-12
IPC分类号： C09D133/10 , A61L27/16 , A61L27/34 , A61L29/04 , A61L29/08 , A61L31/04 , A61L31/10 , C08K5/11 , C09D5/16 , C09D133/26 , C09D151/08
CPC分类号： C09D133/10 , A61L27/16 , A61L27/34 , A61L29/041 , A61L29/085 , A61L31/048 , A61L31/10 , C08K5/11 , C09D5/1675 , C09D133/26 , C09D151/085 , A61L2300/404 , A61L2420/08
摘要： Durable, anti-fouling, crosslinked zwitterionic coatings that are grafted to the surface of a substrate through covalent bonding are disclosed. When exposed to a light source, zwitterionic monomers react with a crosslinker and with activated radicals at the surface of the substrate, simultaneously forming the crosslinked zwitterionic coating and anchoring it to the surface of the substrate. Photomasking techniques can be used to micropattern the zwitterionic coatings. The zwitterionic coatings can be applied to a variety of substrates, including medical devices and systems.
-
28.发明公开公开(公告)号：US20230338626A1
公开(公告)日：2023-10-26
申请号：US18347181
申请日：2023-07-05
发明人： John K. Jackson
IPC分类号： A61L31/16 , A61M25/09 , A61K31/58 , A61K31/436 , A61K31/353 , A61L31/10 , A61L29/16 , A61L29/08 , A61L27/54 , A61L27/44 , A61L27/34 , A61K31/337 , A61L31/08 , A61M25/10
CPC分类号： A61L31/16 , A61M25/09 , A61K31/58 , A61K31/436 , A61K31/353 , A61L31/10 , A61L29/16 , A61L29/085 , A61L27/54 , A61L27/44 , A61L27/34 , A61K31/337 , A61L31/08 , A61L29/08 , A61M25/10 , A61L2300/606 , H05K999/99 , A61M2025/105 , A61L2300/61 , A61L2300/426 , A61L2420/06 , A61L2300/416 , A61L2300/602
摘要： Various aspects of the present disclosure provide compositions including a water-insoluble therapeutic agent and a gallate-containing compound. Other aspects provide methods of using such compositions.
-
公开(公告)号：US20230338623A1
公开(公告)日：2023-10-26
申请号：US18139125
申请日：2023-04-25
申请人： Surmodics, Inc.
CPC分类号： A61L29/16 , A61L29/085 , A61L2300/216 , A61L2300/802 , A61L2300/416
摘要： Embodiments herein relate to medical devices and coatings for the same. In an embodiment, a drug delivery coating can be included having a polymeric layer. The polymeric layer can include a hydrophilic outer surface. The drug delivery coating can also include an active agent layer disposed over the polymeric layer. The active agent layer can include a microcrystalline active agent and a cationic agent. Other embodiments are also included herein.
-
公开(公告)号：US20230338612A1
公开(公告)日：2023-10-26
申请号：US17873980
申请日：2022-07-26
发明人： Russell Martin , Hai-quan Mao
IPC分类号： A61L27/18 , A61L27/48 , A61L27/52 , A61L27/54 , D06M15/03 , A61L29/08 , A61L29/06 , A61K31/00 , A61L29/16 , D06M14/32 , A61L27/28 , D06M15/15 , A61L27/20 , A61L27/24 , A61L27/26 , A61L27/36 , A61L27/56 , A61L27/58 , D01D5/00
CPC分类号： A61L27/18 , A61L27/48 , A61L27/52 , A61L27/54 , D06M15/03 , A61L29/085 , A61L29/06 , A61K31/00 , A61L29/16 , D06M14/32 , A61L27/28 , D06M15/15 , A61L27/20 , A61L27/24 , A61L27/26 , A61L27/3633 , A61L27/56 , A61L27/58 , D01D5/0046 , A61L2400/06 , A61L2400/12 , A61L2430/34 , D06M2101/32
摘要： The presently disclosed composition and methods are provided for an in situ forming nanofiber-hydrogel composite, which is formed using non-covalent binding schemes between the fiber surface and hydrogel-forming polymers. A method for healing a soft tissue defect can include applying the said composite material to a soft tissue defect.
-
-
-
-
-
-
-
-
-
搜索结果
3178 条记录 (耗时 0.022 秒)
