公开(公告)号：US06952946B2

公开(公告)日：2005-10-11

申请号：US10636782

申请日：2003-08-08

申请人： Friedhelm Mueller

发明人： Friedhelm Mueller

IPC分类号： G01N30/62 ,  G01N30/78 ,  G01N30/88 ,  G01N30/02

CPC分类号： G01N30/78 ,  G01N30/465 ,  G01N2030/207 ,  G01N2030/625 ,  G01N2030/8886

摘要： In a gas chromatograph, an injected sample for analysis (3) is passed through a separation device (5) to separate components present in the sample; at the end of the separation device, selected components are detected by a detector (12) and determined quantitatively on the basis of the detector signal (13) supplied by the detector. To permit validation and also to increase the accuracy of the analysis, the sample (3) is determined nondestructively by an additional detector (16) upstream from the separation device (5) and is determined quantitatively on the basis of the additional detector signal (17) supplied by the additional detector (16). The result of the quantitative determination of the sample (3) is used to verify the analysis.

摘要翻译： 在气相色谱仪中，用于分析的注射样品（3）通过分离装置（5）以分离样品中存在的组分; 在分离装置的末端，所选择的分量由检测器（12）检测，并且基于由检测器提供的检测器信号（13）定量确定。 为了允许验证并且还提高分析的准确性，通过分离装置（5）上游的附加检测器（16）非破坏性地确定样本（3），并且基于附加检测器信号（17）定量地确定 ）由附加检测器（16）提供。 样品（3）的定量测​​定结果用于验证分析。

公开(公告)号：US06952945B2

公开(公告)日：2005-10-11

申请号：US09770942

申请日：2001-01-25

申请人： Robert O'Brien

发明人： Robert O'Brien

IPC分类号： G01N33/497 ,  G01N1/00 ,  G01N1/02 ,  G01N1/22 ,  G01N1/24 ,  G01N1/36 ,  G01N1/40 ,  G01N15/00 ,  G01N21/27 ,  G01N21/33 ,  G01N21/35 ,  G01N30/02 ,  G01N30/04 ,  G01N30/06 ,  G01N30/08 ,  G01N30/20 ,  G01N30/22 ,  G01N30/32 ,  G01N30/34 ,  G01N30/46 ,  G01N30/62 ,  G01N30/64 ,  G01N30/68 ,  G01N30/70 ,  G01N30/74 ,  G01N30/78 ,  G01N30/86 ,  G01N30/88 ,  G01N33/00 ,  G01W1/17 ,  G01N30/90

CPC分类号： G01N1/2202 ,  G01N1/24 ,  G01N1/40 ,  G01N30/06 ,  G01N30/22 ,  G01N30/78 ,  G01N30/8606 ,  G01N30/8641 ,  G01N2001/2223 ,  G01N2001/4027 ,  G01N2015/0046 ,  G01N2015/0092 ,  G01N2030/025 ,  G01N2030/328 ,  G01N2030/625 ,  G01N2030/626 ,  G01N30/32

摘要： A method for analyzing a gas sample is described. The method comprises providing a gas sample, increasing pressure applied to the gas sample to compress the sample to a smaller volume and provide a pneumatically focused gas sample, and analyzing the pneumatically focused gas sample using any of a variety of analytical techniques. Pneumatic Focusing generally means increasing the pressure of the sample, column or cell to a pressure of from about 100 psi to about 15,000 psi, more typically from about 200 psi to about 2,000 psi. Examples including gas chromatography and absorption spectroscopy are illustrated herein. Numerous other examples could be given. The method is well suited for analyzing gaseous samples, such as ambient air samples, both continuously, and remotely, using computer control. Continuously sampling ambient air provides a method for real-time monitoring of air quality. Continuous monitoring allows for pollutant exposure and allows for the identification of emission sources. The method is also well suited for analysis of breath exhalations from respiring organisms useful in metabolic studies or disease diagnosis.

摘要翻译： 对气体样品的分析方法进行说明。 该方法包括提供气体样品，增加施加到气体样品的压力以将样品压缩到更小的体积并提供气动聚焦的气体样品，以及使用各种分析技术中的任何一种来分析气动聚焦的气体样品。 气动聚焦通常意味着将样品，柱或细胞的压力提高到约100psi至约15,000psi，更典型地约200psi至约2,000psi的压力。 本文说明了包括气相色谱和吸收光谱的实例。 可以给出很多其他例子。 该方法非常适用于使用计算机控制连续和远程分析气态样品，如环境空气样品。 连续采样环境空气提供了一种实时监测空气质量的方法。 连续监测允许污染物暴露并允许识别排放源。 该方法也非常适用于分析代谢研究或疾病诊断中有用的呼吸生物的呼吸呼气。

公开(公告)号：US20050123452A1

公开(公告)日：2005-06-09

申请号：US10950395

申请日：2004-09-28

申请人： Friedhelm Mueller ,  Udo Gellert

发明人： Friedhelm Mueller ,  Udo Gellert

IPC分类号： G01N30/40 ,  G01N30/46 ,  G01N30/66 ,  G01N30/78 ,  G01N30/02

CPC分类号： G01N30/461 ,  G01N30/40 ,  G01N30/465 ,  G01N30/66 ,  G01N30/78 ,  Y10T436/21

摘要： A gas chromatograph for analyzing natural gas, with a first separation column (6). A first detector (7) is provided following the first separation column, the first separation column and the first detector operable to separate or detect propane and higher hydrocarbons. A second separation column (8) and a second detector (9) following it are provided to separate or detect carbon dioxide and ethane. A third separation column (10) and a third detector (11) following it are provided to separate or detect nitrogen and methane. A controllable changeover device (12) is provided between the second separation column (8) and the third separation column (10) to discharge eluates following methane. The first, second and third separation columns (6, 8, 10) and the first, second and third detectors (7, 9, 11) are connected in series. At least the first and the second detectors (7, 9) are operable to detect a mixture of substances flowing through them in a non-destructive manner.

摘要翻译： 用于分析天然气的气相色谱仪，具有第一分离柱（6）。 在第一分离柱之后提供第一检测器（7），第一分离柱和第一检测器可操作以分离或检测丙烷和高级烃。 提供第二分离塔（8）和跟随其后的第二检测器（9）以分离或检测二氧化碳和乙烷。 提供第三分离塔（10）和随后的第三检测器（11）以分离或检测氮和甲烷。 在第二分离塔（8）和第三分离塔（10）之间设置可控切换装置（12），以排出甲烷后的洗脱液。 第一，第二和第三分离柱（6,8,10）和第一，第二和第三检测器（7,9,11）串联连接。 至少第一和第二检测器（7,9）可操作以检测以非破坏性方式流过它们的物质的混合物。

公开(公告)号：US06868715B1

公开(公告)日：2005-03-22

申请号：US09665767

申请日：2000-09-20

申请人： James Claude Carnahan ,  Paul Edward Gundlach

发明人： James Claude Carnahan ,  Paul Edward Gundlach

IPC分类号： C40B40/14 ,  G01N30/32 ,  G01N30/74 ,  G01N30/78 ,  G01N30/88 ,  G01N33/44 ,  G01N9/00 ,  B01D15/08

CPC分类号： G01N30/88 ,  B01J2219/00707 ,  B01J2219/00722 ,  C40B40/14 ,  G01N30/74 ,  G01N30/78 ,  G01N33/44 ,  G01N2030/324 ,  G01N2030/885 ,  G01N21/4133

摘要： A rapid analysis method for the determination of polymer average molecular weight separates the polymer's high molecular weight fraction and determines its average molecular weight using a molar mass detector and a concentration detector. The method avoids time consuming sample preparation, allows for separation of interfering low molecular weight components, and is suitable for automation.

摘要翻译： 用于测定聚合物平均分子量的快速分析方法分离聚合物的高分子量分数，并使用摩尔质量检测器和浓度检测器确定其平均分子量。 该方法避免了耗时的样品制备，允许分离干扰低分子量组分，适用于自动化。

公开(公告)号：US5654201A

公开(公告)日：1997-08-05

申请号：US524494

申请日：1995-09-07

申请人： Italo A. Capuano

发明人： Italo A. Capuano

IPC分类号： G01N21/33 ,  G01N1/18 ,  G01N21/72 ,  G01N21/77 ,  G01N30/02 ,  G01N30/06 ,  G01N30/40 ,  G01N30/46 ,  G01N30/68 ,  G01N30/74 ,  G01N30/78 ,  G01N30/88

CPC分类号： G01N30/461 ,  G01N1/18 ,  G01N21/72 ,  G01N21/77 ,  G01N30/88 ,  G01N2030/025 ,  G01N2030/402 ,  G01N2030/8886 ,  G01N30/68 ,  G01N30/74 ,  Y10T436/12 ,  Y10T436/153333 ,  Y10T436/19 ,  Y10T436/193333 ,  Y10T436/201666

摘要： An apparatus and method for monitoring the product quality of chlorine in which a sample stream of chlorine is taken from a chlorine stream and a portion of the sample stream is passed to one of three different analyzers for detection of various contaminants. A common data acquisition network receives data from each analyzer for integration and output. The analyzers include a bromine in chlorine analyzer, a non-condensable gas in chlorine analyzer, and a halocarbon in chlorine analyzer.

摘要翻译： 用于监测氯的产物质量的装置和方法，其中从氯气流中取出氯样品流和一部分样品流，将其传送到三种不同分析仪中的一种，以检测各种污染物。 通用数据采集网络从每个分析仪接收数据以进行集成和输出。 分析仪包括氯分析仪中的溴，氯分析仪中的不可冷凝气体和氯分析仪中的卤代烃。

公开(公告)号：US5325704A

公开(公告)日：1994-07-05

申请号：US157847

申请日：1993-11-22

申请人： Elio A. Mariani ,  William J. Skudera, Jr.

发明人： Elio A. Mariani ,  William J. Skudera, Jr.

IPC分类号： G01N29/02 ,  G01N30/00 ,  G01N30/76 ,  G01N30/48 ,  G01N30/78

CPC分类号： G01N29/022 ,  G01N2291/0215 ,  G01N2291/0256 ,  G01N2291/02836 ,  G01N2291/0422 ,  G01N2291/0423 ,  G01N2291/106 ,  G01N30/00

摘要： A sensor for chemical vapor detection using a surface acoustic wave (SAW) ray that provides a means for simultaneously detecting several chemical agents. The sensor has a piezoelectric substrate and a bidirectional surface acoustic wave transducer on the substrate. Also on the substrate are several pairs of identical acoustic sensing and reference channels each on opposite sides of the transducer in a mirror image fashion. Each channel pair has a thin film capable of absorbing a chemical vapor to be monitored and a metallic surface acoustic wave grating reflector capable of receiving and reflecting surface acoustic waves through the thin film and back to the transducer. An acoustic absorber separates each channel. The reference channels are protected from ambient conditions while the sensing channels are exposed to such conditions. An RF signal is applied to the transducer causing the propagation of an acoustic signal into each of the sensing channels and reference channels. Output signals from the transducer are then detected. The array is preferably in a miniature configuration which is suitable for wearing on a person's wrist or arm.

摘要翻译： 一种用于使用表面声波（SAW）阵列进行化学气相检测的传感器，其提供同时检测几种化学试剂的手段。 传感器在衬底上具有压电衬底和双向表面声波传感器。 在衬底上也是几对相同的声学感测和参考通道，每一个以镜像的形式在换能器的相对侧上。 每个通道对具有能够吸收待监测的化学气体的薄膜和能够接收和反射表面声波穿过薄膜并返回到换能器的金属声表面波光栅反射器。 吸声器分隔每个通道。 参考通道受到环境条件的保护，而感测通道暴露在这样​​的条件下。 RF信号被施加到换能器，导致声信号传播到每个感测通道和参考通道中。 然后检测来自换能器的输出信号。 该阵列优选地是适于佩戴在人的手腕或手臂上的微型构型。

公开(公告)号：US5290520A

公开(公告)日：1994-03-01

申请号：US990213

申请日：1992-12-14

申请人： Francois Maystre ,  Alfredo E. Bruno

发明人： Francois Maystre ,  Alfredo E. Bruno

IPC分类号： G02F1/13 ,  C09K19/30 ,  C09K19/46 ,  C09K19/54 ,  G01N30/02 ,  G01N30/34 ,  G01N30/62 ,  G01N30/74 ,  G01N30/78 ,  G01N30/84 ,  G01N21/01

CPC分类号： G01N30/34 ,  G01N30/74 ,  C09K2219/17 ,  G01N2030/027 ,  G01N2030/625 ,  G01N2030/8435 ,  G01N30/78

摘要： An analytic separation arrangement includes a system of tubes including a separation zone, preferably a separation column, which tubes upstream the separation zone are connected with reservoirs for a carrier and a chemical sample to be seperated and analyzed, and downstream the separation zone are connected with a waste container for the carrier containing the sample and also are connected with transporting means for the carrier and the sample. The tube system is associated with an optical detector for monitoring changes in the absorption, in the fluorescence or in the optical activity of the carrier when it is transported through the tube system and past the optical detector, which is arranged in the path of the carrier behind the separation zone but in front of the waste container. Between the separation zone and the optical detector there is arranged in the path of the carrier a refractive index equalizing unit. Prior to being transported past the optical detector the carrier, which is comming from the separation zone, is directed through the refractive index equalizing unit, where its refractive index is preferably constantly monitored and where upon detection of changes of the refractive index of the carrier the deviation is compensated by adding to the carrier a compensating agent.

摘要翻译： 分析分离装置包括管系统，其包括分离区，优选分离塔，分离区上游的管与用于载体和待分离和分析的化学样品的储存器连接，分离区的下游与 用于包含样品的载体的废物容器，并且还与用于载体和样品的输送装置连接。 管系统与光学检测器相关联，用于监测载体在其被传送通过管系统并经过光学检测器的荧光或荧光光学活性时的变化，光检测器布置在载体的路径中 在分离区后面，但在废物容器前面。 在分离区域和光学检测器之间，在载体的路径中布置折射率均衡单元。 在被传送通过光学检测器之前，从分离区转移的载体被引导通过折射率均衡单元，其折射率优选地被不断地监测，并且在检测到载体的折射率变化的地方 通过向载体添加补偿剂来补偿偏差。

公开(公告)号：US5281256A

公开(公告)日：1994-01-25

申请号：US975289

申请日：1992-11-12

申请人： Richard D. Sacks ,  Michael L. Akard

发明人： Richard D. Sacks ,  Michael L. Akard

IPC分类号： G01N30/26 ,  G01N1/00 ,  G01N1/22 ,  G01N1/26 ,  G01N30/02 ,  G01N30/12 ,  G01N30/20 ,  G01N30/24 ,  G01N30/30 ,  G01N30/32 ,  G01N30/38 ,  G01N30/40 ,  G01N30/46 ,  G01N30/62 ,  G01N30/68 ,  G01N30/78 ,  G01N30/86 ,  B01D15/08

CPC分类号： G01N30/468 ,  G01N1/26 ,  G01N30/12 ,  G01N30/20 ,  G01N30/38 ,  G01N30/40 ,  G01N1/2214 ,  G01N2030/025 ,  G01N2030/121 ,  G01N2030/122 ,  G01N2030/201 ,  G01N2030/202 ,  G01N2030/204 ,  G01N2030/3046 ,  G01N2030/383 ,  G01N2030/385 ,  G01N2030/402 ,  G01N2030/405 ,  G01N2030/407 ,  G01N2030/623 ,  G01N2030/628 ,  G01N30/24 ,  G01N30/32 ,  G01N30/461 ,  G01N30/466 ,  G01N30/68 ,  G01N30/78 ,  G01N30/8651 ,  G01N35/1097

摘要： A gas chromatography system featuring column bifurcation and pressure tuning. The system of this invention incorporates a bifurcated system in which samples eluting from a first separation column are directed selectively through one of two or more additional separation columns. Flow directing is achieved through the use of valves which switch carrier gas which are outside of the path of the analyte mixture. Effective tuning of the system is provided by adjusting the intermediate pressure which controls the effective lengths of the initial separation column and the additional final separation columns.

摘要翻译： 具有柱分岔和压力调节的气相色谱系统。 本发明的系统包含分叉系统，其中从第一分离柱洗脱的样品选择性地通过两个或更多个附加分离柱之一。 通过使用在分析物混合物的路径之外切换载气的阀来实现流动引导。 通过调节控制初始分离柱和附加最终分离柱的有效长度的中间压力来提供系统的有效调节。

公开(公告)号：US5194133A

公开(公告)日：1993-03-16

申请号：US695429

申请日：1991-05-03

申请人： Michael G. Clark ,  Rosemary A. Lee ,  Christopher R. Lowe ,  Philip Maynard ,  Rajinder S. Sethi ,  Donald J. Weir

发明人： Michael G. Clark ,  Rosemary A. Lee ,  Christopher R. Lowe ,  Philip Maynard ,  Rajinder S. Sethi ,  Donald J. Weir

IPC分类号： G01N27/447 ,  G01N27/27 ,  G01N27/28 ,  G01N27/403 ,  G01N30/46 ,  G01N30/60 ,  G01N30/64 ,  G01N30/78 ,  G01N37/00

CPC分类号： G01N30/78 ,  G01N27/27 ,  G01N30/64 ,  G01N2030/645 ,  G01N30/466 ,  G01N30/6095 ,  Y10S436/806

摘要： A sensor device for the analysis of a sample fluid comprises a substrate in a surface of which an elongate channel is micromachined. The channel contains a material, such as a starch, agarose, alginate, carrageenin or polyacrylic polymer gel, with a biological material for causing separation of the sample fluid as the fluid passes along the channel. The biological material may comprise, for example, a binding protein, an antibody, a lectin, an enzyme, a sequence of enzymes or a lipid. Pairs of sensing electrodes are spaced apart along the walls of the channel. The device may be used, for example, for testing blood samples.

公开(公告)号：US4462962A

公开(公告)日：1984-07-31

申请号：US512678

申请日：1983-07-11

申请人： Nobuyuki Baba ,  Keiichi Housako

发明人： Nobuyuki Baba ,  Keiichi Housako

IPC分类号： G01N21/05 ,  G01N27/07 ,  G01N30/64 ,  G01N30/74 ,  G01N30/78 ,  B01D15/08

CPC分类号： G01N30/78 ,  G01N30/64 ,  G01N30/74 ,  G01N2030/746

摘要： A liquid chromatographic flow cell for measuring constituents of a specimen solution, comprising at least two electrodes, each having a first through hole, an insulating member having a second through hole and so disposed as to electrically insulate the electrodes from each other, a first and a second supporting members for clamping therebetween the electrodes and the insulating member in such a way that the first and the second through holes are coaxially aligned so as to define a first passage of the specimen solution and having, respectively, a second passage and a third passage of the specimen solution which communicate with the first passage, a first light guiding member for guiding a light for measuring an absorbance of the specimen solution into the second passage defined in the first supporting member, and a second light guiding member for guiding the light transmitted through the third passage defined in the second supporting member to means for measuring an absorbance of the specimen solution. Both the electric conductivity and absorbance of the constituents of a specimen solution dissolved from a column can be measured simultaneously and continuously within the same cell.

摘要翻译： 一种用于测量样品溶液成分的液相色谱流通池，包括至少两个电极，每个电极具有第一通孔，具有第二通孔的绝缘构件，并被设置成使电极彼此电绝缘;第一和第二通孔， 用于将电极和绝缘构件夹持在其间的第二支撑构件，使得第一和第二通孔同轴对准，以便限定样本溶液的第一通道，并且分别具有第二通道和第三通道 与第一通道连通的试样溶液的通道，用于引导用于测量样品溶液的吸光度的光的第一导光构件到限定在第一支撑构件中的第二通道中;第二导光构件，用于引导光 通过限定在第二支撑构件中的第三通道传递到用于测量吸光度的装置 标本溶液。 从柱中溶出的试样溶液的成分的电导率和吸光度都可以在相同的电池内同时并连续测量。