公开(公告)号：US20160267245A1

公开(公告)日：2016-09-15

申请号：US14404108

申请日：2014-08-21

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY INFORMATION

Inventor： In Sung AHN

IPC: G06F19/00 ,  G06N7/00

CPC classification number: G16H50/50 ,  G06N7/005 ,  G16B30/00

Abstract: The present invention relates to a storage medium for storing a mutated genome sequence prediction program to receive input of a first genome sequence group and a second sequence group including each of a plurality of genome sequences, to calculate genome mutation between the first genome sequence group and the second genome sequence group using a distributed processing technique, to generate multiple mutation parameters represented by a 61 by 61 matrix using the calculation result, to generate mutated genome sequences of seed genome sequences using the multiple mutation parameters, and to display the generate mutated genome sequences.

Abstract translation: 本发明涉及一种用于存储突变基因组序列预测程序以接收第一基因组序列组的输入和包括多个基因组序列中的每一个的第二序列组的存储介质，以计算第一基因组序列组和第 使用分布式处理技术的第二基因组序列组，使用计算结果生成由61乘61矩阵表示的多个突变参数，以使用多重突变参数产生种子基因组序列的突变基因组序列，并显示产生的突变基因组 序列。

公开(公告)号：US09422191B2

公开(公告)日：2016-08-23

申请号：US14178947

申请日：2014-02-12

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Heon Ju Lee ,  Myoung Woon Moon ,  Ji Hyun So ,  Eu Sun Yu ,  Tae Jun Ko ,  Seock Heon Lee ,  Do Hyun Kim ,  Kyu Hwan Oh

IPC: C03C25/68 ,  B32B37/00 ,  C23C16/26 ,  C23C16/505 ,  D06M10/00

CPC classification number: C03C25/68 ,  B01D39/083 ,  B01D2239/0428 ,  B01D2239/10 ,  C23C16/26 ,  C23C16/505 ,  D06M10/00 ,  D06M10/025 ,  D06M10/04 ,  D06M10/08 ,  D06M13/513

Abstract: A method to prepare polymer woven fabric surface with selective oleophilicity or hydrophobicity and oil-oil separation and oil-water separation filter prepared by using the surface. The method to prepare the surface with selective oleophilicity or hydrophobicity includes steps comprising a step to form nano meter sized pores on the surface of the polymer woven fabric surface with micro sized pores through drying type etching; and a step to form selective oleophobic or hydrophobic film on the nano meter sized pores. It is possible to control hydrophobic/oleophobic property according to pore size, material or thickness of the film and this polymer surface with hybrid pores can be used in various areas such as an oil filter for car capable of selective separation of oil-oil mixture and water-oil mixture, disposal of waste oil, treatment of marine oil leakage, and pretreatment of crude oil refinement.

Abstract translation: 一种制备具有选择性亲油性或疏水性的聚合物织物表面的方法以及通过使用表面制备的油 - 油分离和油水分离过滤器。 制备具有选择性亲油性或疏水性的表面的方法包括以下步骤：在聚合物织物表面上通过干燥型蚀刻形成具有微孔的孔的纳米尺寸孔的步骤; 以及在纳米尺寸孔上形成选择性疏油或疏水膜的步骤。 可以根据孔径，材料或薄膜的厚度控制疏水性/疏油性，并且具有杂化孔的聚合物表面可以用于各种领域，例如能够选择性分离油 - 油混合物的汽车滤油器， 水油混合物，废油处理，海油泄漏处理，原油精炼预处理。

公开(公告)号：US09409781B2

公开(公告)日：2016-08-09

申请号：US13871285

申请日：2013-04-26

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Han-Ik Joh ,  Su Young Son ,  Sung Ho Lee ,  Tae-Wook Kim

IPC: C01B31/04 ,  B32B18/00 ,  C04B35/524 ,  C04B35/622 ,  C04B38/00 ,  B01J37/02 ,  B01J23/40 ,  B01J23/70 ,  B01J35/00 ,  B01J35/06 ,  C04B111/00

CPC classification number: C01B31/0446 ,  B01J23/40 ,  B01J23/70 ,  B01J35/0013 ,  B01J35/06 ,  B01J35/065 ,  B01J37/0215 ,  B01J37/0232 ,  B32B18/00 ,  C01B32/184 ,  C01B2204/04 ,  C01B2204/32 ,  C04B35/524 ,  C04B35/62222 ,  C04B38/0032 ,  C04B2111/00844 ,  C04B2237/363 ,  C04B35/52

Abstract: The present disclosure relates to a polymer-based large-area carbon nanomesh and a method for preparing same. More particularly, the present disclosure provides a method for preparing a carbon nanomesh, including: preparing a polymer nanofilm by coating a solution of a block copolymer or a polymer mixture thereof on a substrate; stabilizing the polymer nanofilm by annealing such that the polymer nanofilm is phase-separated, a pore-forming polymer is removed and, at the same time, a nanomesh-forming polymer forms a stabilized porous polymer nanomesh; and carbonizing the stabilized porous polymer nanomesh by annealing at high temperature to prepare a carbon nanomesh. Using phase separation and cyclization of a polymer, a large-area carbon nanomesh with superior activity can be prepared simply with high reproducibility in large scale.

Abstract translation: 本公开内容涉及基于聚合物的大面积碳纳米体及其制备方法。 更具体地说，本公开内容提供了制备碳纳米管的方法，包括：通过将嵌段共聚物或其聚合物混合物的溶液涂布在基材上来制备聚合物纳米薄膜; 通过退火来稳定聚合物纳米薄膜，使得聚合物纳米薄膜相分离，除去成孔聚合物，同时形成纳米成型聚合物形成稳定的多孔聚合物纳米薄膜; 并通过在高温下退火来碳化稳定化的多孔聚合物纳米颗粒以制备碳纳米薄膜。 使用聚合物的相分离和环化，可以简单地以大规模的高再现性制备具有优异活性的大面积碳纳米体。

公开(公告)号：US20160221156A1

公开(公告)日：2016-08-04

申请号：US14970923

申请日：2015-12-16

Applicant: Korea Institute of Science and Technology

Inventor： Young Joon BAIK ,  Jong-Keuk PARK ,  Wook Seong LEE

IPC: B24D18/00 ,  C01B31/36

CPC classification number: B24D18/00 ,  C01B32/956

Abstract: A superhard boron carbide thin film with superior high temperature oxidation resistance has a structure in which a boron carbide layer and a silicon carbide layer are repeatedly stacked in an alternating manner. Accordingly, the high temperature oxidation resistance of the boron carbide thin film is enhanced, allowing the application as coating materials for wear resistant tools such as cutting tools.

Abstract translation: 具有优异的高温抗氧化性的超硬碳化硼薄膜具有以交替方式重复堆叠碳化硼层和碳化硅层的结构。 因此，提高了碳化硼薄膜的高温抗氧化性，可以作为耐磨工具如切削工具的涂料。

公开(公告)号：US20160208245A1

公开(公告)日：2016-07-21

申请号：US14754556

申请日：2015-06-29

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Hyung Jun AHN ,  Ick Chan KWON ,  Mihue JANG ,  Jong Hwan KIM

IPC: C12N15/113

CPC classification number: C12N15/111 ,  C12N2310/14 ,  C12N2310/3515 ,  C12N2310/531 ,  C12N2320/32

Abstract: A RNA/DNA nanoparticle for delivering siRNA where a RNA transcript including at least one hairpin structure hybridizes DNA-cholesterol conjugate and folate-DNA conjugate including a complementary sequence to the RNA transcript, and a composition including the RNA/DNA nanoparticle is provided. More specifically, because various siRNA used for different applications can be contained in the RNA/DNA nanoparticle for delivering siRNA at a high loading efficiency, and has stability to the outer attacks such as nuclease degradation. The RNA/DNA nanoparticle siRNA can be prepared by self-assembly without using polycationic agent which is harmful agent for body. The folate targeting to various cancer cells can accumulate the nanoparticle selectively on target cancer cell after intravenous injection, and make excellent gene-silencing effect inside the cancer tissue, thereby being used as a good agent for treating cancers.

Abstract translation: 提供了用于递送siRNA的RNA / DNA纳米颗粒，其中包含至少一个发夹结构的RNA转录物与DNA-胆固醇缀合物和包含与RNA转录物的互补序列的叶酸-DNA缀合物杂交，并且包含RNA / DNA纳米颗粒的组合物。 更具体地，因为用于不同应用的各种siRNA可以包含在用于以高负载效率递送siRNA的RNA / DNA纳米颗粒中，并且对外部攻击如核酸酶降解具有稳定性。 RNA / DNA纳米颗粒siRNA可以通过自组装制备，而不使用作为身体有害物质的聚阳离子。 针对各种癌细胞的叶酸可以在静脉注射后在靶癌细胞上选择性地积聚纳米颗粒，并且在癌组织内部具有优异的基因沉默效果，从而被用作治疗癌症的良好剂。

公开(公告)号：US20160202208A1

公开(公告)日：2016-07-14

申请号：US14925172

申请日：2015-10-28

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Kwan Hyi LEE ,  Seok LEE ,  Minhong JEUN ,  Inkyu LEE ,  Jung Hoon PARK ,  Won-Ju CHO ,  Hyun-June JANG

IPC: G01N27/414

CPC classification number: G01N27/4145

Abstract: A multiplexing detection system of a dual gate ion-sensitive field effect transistor bio sensor of the present invention includes: a first dual gate ion-sensitive field effect transistor bio sensor; and a second dual gate ion-sensitive field effect transistor bio sensor, wherein a first bio signal is sensed through the first dual gate ion-sensitive field effect transistor bio sensor, and a second bio signal is sensed through the second dual gate ion-sensitive field effect transistor bio sensor, and the first bio signal and the second bio signal are different in type from each other.

Abstract translation: 本发明的双栅离子敏感场效应晶体管生物传感器的复用检测系统包括：第一双栅极离子敏感场效应晶体管生物传感器; 以及第二双栅极离子敏感场效应晶体管生物传感器，其中通过第一双栅离子敏感场效应晶体管生物传感器感测第一生物信号，并且通过第二双栅离子敏感感测第二生物信号 场效应晶体管生物传感器，第一生物信号和第二生物信号的类型彼此不同。

公开(公告)号：US20160191281A1

公开(公告)日：2016-06-30

申请号：US14911275

申请日：2013-11-01

Applicant: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY ,  KOREA BASIC SCIENCE INSTITUTE ,  KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： InnYeal OH ,  ChulSoon PARK ,  MinChul SHIN ,  SeungYoung PARK ,  ByoungChul MIN ,  SukHee HAN

IPC: H04L27/04 ,  H04L5/00 ,  H04L25/49

CPC classification number: H04L27/04 ,  H01F10/32 ,  H01F10/329 ,  H01L43/00 ,  H03B15/006 ,  H04L5/0005 ,  H04L5/06 ,  H04L25/4917 ,  H04L27/06

Abstract: A spintronic wireless communication system for simultaneously modulating multiband frequencies and amplitudes includes a plurality of spin-torque transfer devices which have different frequency characteristics from each other, and OOK modulate or multi-level ASK modulate input data to thereby output a multiband OOK modulation signal or a multiband, multi-level ASK modulation signal; a plurality of matching networks which match individual impedances of the plurality of spin-torque transfer devices; and a broadband antenna which receives the multiband OOK modulation signal or the multiband, multi-level ASK modulation signal from ends of the plurality of matching networks and simultaneously transmits the signals to the outside.

Abstract translation: 用于同时调制多频率和幅度的自旋电子无线通信系统包括彼此具有不同频率特性的多个自旋转矩传递装置，并且OOK调制或多电平ASK调制输入数据，从而输出多频带OOK调制信号或 一个多频段多级ASK调制信号; 多个匹配网络，其匹配多个自旋转矩传递装置的各个阻抗; 以及宽带天线，其从多个匹配网络的端部接收多频带​​OOK调制信号或多频带多电平ASK调制信号，同时将信号发送到外部。

公开(公告)号：US20160184430A1

公开(公告)日：2016-06-30

申请号：US14974490

申请日：2015-12-18

Applicant: Korea Institute of Science and Technology

Inventor： Ju-Hee Ryu ,  Kwang-Meyung Kim ,  Ick-Chan Kwon ,  Kui-Won Choi ,  Sang-Yoon Kim ,  Beom-Suk Lee ,  Dae-Yoon Chi ,  Hee-Seup Kil ,  Hyun-Ju Sung

IPC: A61K41/00 ,  A61N5/06 ,  A61K47/48 ,  A61N5/10 ,  A61K9/00 ,  A61K31/704

CPC classification number: A61K41/0042 ,  A61K31/704 ,  A61K38/00 ,  A61K47/64 ,  A61N5/062 ,  A61N5/1001

Abstract: The present invention relates to an anticancer prodrug consisting of peptide of acetyl-SEQ ID NO: 1-linker-anticancer drug. The anticancer prodrug effectively provides an anticancer drug unstable in acid and base, such as doxorubicin, in a form of prodrug. Thus, the anticancer prodrug exists as a non-toxic inactive form when administered into the body, but effectively releases the anticancer drug as an active ingredient in the target area in the presence of caspase activated by radiation or UV treatment after administered into the body. Accordingly, the anticancer drug exhibits selective anticancer effects on cancer cells, thereby maximizing the therapeutic effect and minimizing the side-effects of chemotherapy.

Abstract translation: 本发明涉及一种由乙酰基-SEQ ID NO.1-接头 - 抗癌药物的肽组成的抗癌药物。 抗癌前药有效地提供了在酸和碱中不稳定的抗癌药物，例如以前药形式的多柔比星。 因此，当施用于体内时，抗癌前药以无毒无活性形式存在，但在施用于体内后，通过辐射或UV治疗活化的半胱天冬酶存在下，有效地将抗癌药物作为活性成分释放到目标区域。 因此，抗癌药物对癌细胞具有选择性的抗癌作用，从而最大化治疗效果并使化疗的副作用最小化。

公开(公告)号：US09358522B2

公开(公告)日：2016-06-07

申请号：US13667797

申请日：2012-11-02

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Seok Won Hong ,  Sang Hyup Lee ,  Jae Woo Choi ,  Seung Gun Chung

IPC: B01J20/18 ,  B01J20/28 ,  B01J20/22 ,  B01J20/285 ,  B01J20/02 ,  B01J20/24 ,  B01J20/06 ,  B01J20/30 ,  B01J20/32 ,  C02F1/28 ,  C02F101/20

CPC classification number: B01J20/28019 ,  B01J20/0229 ,  B01J20/06 ,  B01J20/18 ,  B01J20/22 ,  B01J20/223 ,  B01J20/24 ,  B01J20/2803 ,  B01J20/285 ,  B01J20/3014 ,  B01J20/3078 ,  B01J20/3085 ,  B01J20/3204 ,  B01J20/3257 ,  C02F1/281 ,  C02F1/286 ,  C02F1/288 ,  C02F2101/20

Abstract: A composite medium and method thereof for simultaneous removal of cationic and anionic heavy metals are provided to remove cationic and anionic heavy metals effectively. The method includes dissolving sodium alginate powder into deionized water to provide an alginate solution, and introducing amine group-supported mesoporous iron oxide and synthetic zeolite into the alginate solution and kneading the resultant mixture. The method also includes adding the alginate solution mixed with the mesoporous iron oxide and synthetic zeolite dropwise to an aqueous calcium chloride solution so that each drop of alginate solution is cured to form a bead-like composite medium, and vacuum drying the bead-like composite medium to remove water present in the composite medium, while the mesoporous iron oxide and synthetic zeolite are moved from the inside of the composite medium toward the surface of the composite medium.

Abstract translation: 提供用于同时去除阳离子和阴离子重金属的复合介质及其方法以有效地去除阳离子和阴离子重金属。 该方法包括将藻酸钠粉末溶解在去离子水中以提供藻酸盐溶液，并将胺基担载的介孔氧化铁和合成沸石引入到藻酸盐溶液中并捏合所得混合物。 该方法还包括将中孔氧化铁和合成沸石混合的藻酸盐溶液滴加到氯化钙水溶液中，使每一滴藻酸盐溶液固化形成珠状复合介质，真空干燥珠状复合材料 介质以除去存在于复合介质中的水，同时介孔氧化铁和合成沸石从复合介质的内部朝向复合介质的表面移动。

公开(公告)号：US20160156049A1

公开(公告)日：2016-06-02

申请号：US14939970

申请日：2015-11-12

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Heung Yong HA ,  Myunggi AN ,  Jinyeon HWANG ,  Asad MEHMOOD

IPC: H01M8/04

CPC classification number: H01M8/04798 ,  H01M8/04067 ,  H01M8/04164 ,  H01M8/04186 ,  H01M8/04365 ,  H01M8/0438 ,  H01M8/04552 ,  H01M8/04582 ,  H01M8/04731 ,  H01M8/04992 ,  H01M8/1009 ,  H01M8/1011 ,  Y02E60/523

Abstract: Disclosed is an apparatus for controlling a fuel concentration of a liquid fuel cell apparatus by voltage amplitude control-based feed-back control without using a concentration sensor, which saves power consumed by the fuel cell apparatus and lowers a price of the fuel cell apparatus by using the fuel cell in a simple and small design without using a concentration sensor.

Abstract translation: 公开了一种用于通过基于电压幅度控制的反馈控制来控制液体燃料电池装置的燃料浓度的装置，而不使用浓度传感器，其节省了燃料电池装置消耗的电力并降低了燃料电池装置的价格 以简单而小巧的设计使用燃料电池，而不使用浓度传感器。