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    SYSTEMS AND METHODS FOR CORPORATE WORKPLACE CAPACITY PLANNING AND OPTIMIZATION
    31.
    发明申请
    SYSTEMS AND METHODS FOR CORPORATE WORKPLACE CAPACITY PLANNING AND OPTIMIZATION 审中-公开
    企业工作能力规划与优化的系统与方法

    公开(公告)号：US20090254389A1

    公开(公告)日：2009-10-08

    申请号：US12062616

    申请日：2008-04-04

    申请人： Benjamin T. Teal ,  Margaret A. Lynne ,  Michael Parker ,  Charles Kosior ,  Unnikrishnan P. Vasudevannnair ,  Dan Yang

    发明人： Benjamin T. Teal ,  Margaret A. Lynne ,  Michael Parker ,  Charles Kosior ,  Unnikrishnan P. Vasudevannnair ,  Dan Yang

    IPC分类号： G06Q10/00

    CPC分类号： G06Q10/06 ,  G06Q10/04 ,  G06Q10/0631

    摘要： Systems and methods for corporate workplace capacity planning and optimization are provided. A system according to the invention may include a computer. The computer may be configured to receive a plurality of characteristics relating to an entity or a portion of an entity. The computer may be further configured to receive a predetermined selection of buildings. The computer may also be configured to determine a plurality of solution sets. Each of the solution sets may express a subset of space located within the selected buildings for the location of the entity or the portion of the entity. The solution sets may be fixed for a predetermined amount of time into the future. The solutions sets can be based, at least in part, on the plurality of characteristics. The computer may also be configured to select a subset of the plurality of solution sets. Finally, a display device may be configured to display at least a portion of a single solution set.

    摘要翻译： 提供了企业工作场所能力规划和优化的系统和方法。 根据本发明的系统可以包括计算机。 计算机可以被配置为接收与实体或实体的一部分有关的多个特征。 计算机可以被进一步配置为接收预定的建筑物选择。 计算机还可以被配置为确定多个解集。 每个解决方案集可以表示位于所选择的建筑物内的空间的子集，用于实体或实体的部分的位置。 解决方案集可以在将来固定预定的时间量。 解决方案集可以至少部分地基于多个特征。 计算机还可以被配置为选择多个解集合的子集。 最后，显示设备可以被配置为显示单个解集合的至少一部分。

    FLUOROPHORE COMPOUNDS
    32.
    发明申请
    FLUOROPHORE COMPOUNDS 有权
    氟化合物

    公开(公告)号：US20090253143A1

    公开(公告)日：2009-10-08

    申请号：US12417640

    申请日：2009-04-03

    申请人： Dan Yang ,  Tao Peng

    发明人： Dan Yang ,  Tao Peng

    IPC分类号： C12Q1/68 ,  C07D493/10 ,  C12Q1/00 ,  G01N33/53 ,  C12Q1/02

    CPC分类号： C07D493/10 ,  G01N33/582

    摘要： Provided herein are fluorophore compounds including rhodol and rhodamine compounds which can be used as fluorescent labels and/or fluorogenic probes and methods of making same. Provided also herein are methods that can be used to track, measure, detect, or screen biological species such as protein, DNA, enzyme, antibody, organelle, cell, tissue, drug, hormone, nucleotide, nucleic acid, polysaccharide or lipid in living organisms. Specifically, the methods include the steps of contacting any of the fluorophore compounds, rhodol compounds and rhodamine compounds disclosed herein with the biological species to form one or more fluorescent compounds, and measuring fluorescence properties of the fluorescent compounds. Provided also herein are high-throughput screening fluorescent methods for detecting or screening biological species.

    摘要翻译： 本文提供了可用作荧光标记和/或荧光探针的罗丹明和罗丹明化合物的荧光团化合物及其制备方法。 本文还提供了可用于跟踪，测量，检测或筛选生物物种如蛋白质，DNA，酶，抗体，细胞器，细胞，组织，药物，激素，核苷酸，核酸，多糖或脂质在生物中的方法 生物体。 具体地说，这些方法包括使本文公开的任何荧光团化合物，罗丹明化合物和罗丹明化合物与生物物质接触以形成一种或多种荧光化合物，并测量荧光化合物的荧光性质的步骤。 本文还提供了用于检测或筛选生物物种的高通量筛选荧光方法。

    Method for synthesizing 5β, 6β-epoxides of steroids by a highly β-selective epoxidation of ΔΔ5-unsaturated steroids catalyzed by ketones
    33.
    发明授权
    Method for synthesizing 5β, 6β-epoxides of steroids by a highly β-selective epoxidation of ΔΔ5-unsaturated steroids catalyzed by ketones 有权
    通过酮催化的DeltaDelta5-不饱和类固醇的高度β选择性环氧化合成类固醇的5β，6β-环氧化物的方法

    公开(公告)号：US06841665B2

    公开(公告)日：2005-01-11

    申请号：US10091627

    申请日：2002-03-06

    申请人： Dan Yang ,  Guan-Sheng Jiao

    发明人： Dan Yang ,  Guan-Sheng Jiao

    IPC分类号： C07J71/00

    CPC分类号： C07J71/00

    摘要： A general, efficient, and environmentally friendly method is provided for producing mostly β-epoxides of Δ5-unsaturated steroids using certain ketones as the catalyst along with an oxidizing agent, or by using certain dioxiranes. In another aspect of the invention, a method is provided for producing mostly 5β,6β-epoxides of steroids from Δ5-unsaturated steroids having a substituent at the 3α-position by an epoxidation reaction using a ketone along with an oxidizing agent under conditions effective to generate epoxides, or using a dioxirane under conditions effective to generate epoxides. A whole range of Δ5-unsaturated steroids, bearing different functional groups such as hydroxy, carbonyl, acetyl or ketal group as well as different side chains, were conveniently converted to the corresponding synthetically and biologically interesting 5β,6β-epoxides with excellent β-selectivities and high yields.

    摘要翻译： 提供了一般的，有效的和环境友好的方法来生产大部分为δ5-不饱和类固醇的β-环​​氧化物，其中使用某些酮作为催化剂以及氧化剂，或通过使用某些二环氧烷。 在本发明的另一方面，提供了一种用于通过环氧化反应使用酮与氧化剂一起在3α-位置上具有取代基的5α-不饱和类固醇产生类固醇的5β，6β-环氧化物的方法， 有效产生环氧化物的条件，或在有效产生环氧化物的条件下使用二氧杂环烷。 具有不同官能团（如羟基，羰基，乙酰基或缩酮基团）以及不同侧链的全部Delta 5'不饱和类固醇可方便地转化为相应的合成和生物学上有趣的5α，6β-环氧化物 β选择性和高产量。