公开(公告)号：US08267862B2

公开(公告)日：2012-09-18

申请号：US12474520

申请日：2009-05-29

申请人： Ji Wook Jeong ,  Yong Won Jang ,  Seung Hwan Kim ,  Seon Hee Park

发明人： Ji Wook Jeong ,  Yong Won Jang ,  Seung Hwan Kim ,  Seon Hee Park

IPC分类号： A61B5/00 ,  A61B5/08

CPC分类号： A61B5/1135 ,  A61B5/01 ,  A61B5/0205 ,  A61B5/02055 ,  A61B5/02438 ,  A61B5/0245 ,  A61B5/0402 ,  A61B5/0816 ,  A61B5/6804 ,  A61B5/681 ,  A61B5/6824 ,  A61B5/6831 ,  G06F19/00 ,  G16H50/30

摘要： Provided are an apparatus and method for monitoring a health index using an electroconductive fiber. In the apparatus, a bio signal acquiring unit measures a bio signal using an electroconductive fiber which is worn around a part of a user's body and in which a resistance is varied according to a user's body volume or body temperature. A health index acquiring unit analyzes the bio signal to acquire a health index. A health index notifying unit notifies the health index. Accordingly, the health index can be easily monitored without limitations on the user's behavior.

摘要翻译： 提供了一种使用导电纤维监测健康指数的装置和方法。 在该装置中，生物信号获取单元使用在用户身体的一部分周围佩戴的导电纤维来测量生物信号，并且根据使用者的身体体积或体温来改变阻力。 健康指数获取单元分析生物信号以获得健康指数。 健康指标通知单元通知健康指数。 因此，可以容易地监视健康指数，而不会限制用户的行为。

公开(公告)号：US08228502B2

公开(公告)日：2012-07-24

申请号：US12545170

申请日：2009-08-21

申请人： Hyunsung Ko ,  Chul Huh ,  Kyung Hyun Kim ,  Wanjoong Kim ,  Bong Kyu Kim ,  Gun Yong Sung ,  Seon Hee Park

发明人： Hyunsung Ko ,  Chul Huh ,  Kyung Hyun Kim ,  Wanjoong Kim ,  Bong Kyu Kim ,  Gun Yong Sung ,  Seon Hee Park

IPC分类号： G01J3/28

CPC分类号： G01N21/55 ,  G01J3/10 ,  G01N21/77 ,  G01N2021/7773 ,  G01N2021/7783

摘要： Provided is a measurement device. The measurement device includes a sensor, a wavelength-tunable light source, an additional light source, a coupler, and an optical power measurer. The sensor accepts a sample. The wavelength-tunable light source irradiates wavelength-tunable light to detect a reaction of the sensor. The additional light source irradiates wavelength-fixed light to detect an initial time of the reaction. The coupler combines the wavelength-tunable light source and the additional light source and irradiates the combined input light on the sensor. The optical power measurer detects the reaction of the sensor from an output light transmitted through or reflected by the sensor.

摘要翻译： 提供了一种测量装置。 测量装置包括传感器，波长可调光源，附加光源，耦合器和光功率测量器。 传感器接受样品。 波长可调光源照射波长可调光以检测传感器的反应。 附加的光源照射波长固定的光以检测反应的初始时间。 耦合器将波长可调光源和附加光源相结合，并将传感器上的组合输入光照射。 光功率测量器检测传感器从传感器传输或反射的输出光的反应。

公开(公告)号：US20110091905A1

公开(公告)日：2011-04-21

申请号：US12893166

申请日：2010-09-29

申请人： Chil Seong AH ,  Gun Yong Sung ,  Wan Joong Kim ,  Bong Kyu Kim ,  Jong Cheol Hong ,  Chul Huh ,  Seon Hee Park

发明人： Chil Seong AH ,  Gun Yong Sung ,  Wan Joong Kim ,  Bong Kyu Kim ,  Jong Cheol Hong ,  Chul Huh ,  Seon Hee Park

IPC分类号： G01N33/53 ,  G01N21/17 ,  C12M1/34 ,  G01N30/00

CPC分类号： G01N33/5302 ,  G01N21/31

摘要： Provided are a biochip and a method of detecting a reaction from the biochip. This method includes preparing a first mixture solution of polyvinylpyrrolidone (PVP) and a sample including target molecules, measuring absorbance or transmittance of the first mixture solution, preparing a second mixture solution including the PVP, the sample, and a receptor of the target molecules, measuring absorbance or transmittance of the second mixture solution, and calculating an absorbance or transmittance difference between the first mixture solution and the second mixture solution. Thus, it is possible to reduce the production cost of the biochip by inducing a reaction of an antigen and an antibody using PVP. Further, it is possible to detect an accurate quantity of the antigen by analyzing a quantity of antigen on the basis of the absorbance or transmittance difference.

摘要翻译： 提供了一种生物芯片和从生物芯片检测反应的方法。 该方法包括制备聚乙烯吡咯烷酮（PVP）的第一混合溶液和包含靶分子的样品，测量第一混合溶液的吸光度或透射率，制备包含PVP，样品和靶分子的受体的第二混合溶液， 测量第二混合溶液的吸光度或透射率，并计算第一混合溶液和第二混合溶液之间的吸光度或透射率差异。 因此，通过使用PVP诱导抗原和抗体的反应，可以降低生物芯片的生产成本。 此外，可以通过基于吸光度或透射率差异分析抗原量来检测精确量的抗原。

公开(公告)号：US20110053290A1

公开(公告)日：2011-03-03

申请号：US12858158

申请日：2010-08-17

申请人： Chang Geun Ahn ,  Chan Woo Park ,  Jong Heon Yang ,  Tae Youb Kim ,  Chil Seong Ah ,  An Soon Kim ,  Bong Kyu Kim ,  Gun Yong Sung ,  Seon Hee Park

发明人： Chang Geun Ahn ,  Chan Woo Park ,  Jong Heon Yang ,  Tae Youb Kim ,  Chil Seong Ah ,  An Soon Kim ,  Bong Kyu Kim ,  Gun Yong Sung ,  Seon Hee Park

IPC分类号： G01N33/566 ,  H01L29/772

CPC分类号： G01N21/75 ,  B01L3/502761 ,  B01L2200/0668 ,  B01L2300/0645 ,  B01L2400/043 ,  G01N21/253 ,  G01N35/0098 ,  G01N2035/00158 ,  G01N2035/00237 ,  H01L27/14601

摘要： Provided is a biosensor chip. The biosensor chip includes a plurality of biosensor cells that are arranged in a matrix and selectively generate and output a sensed signal by addressing of external light, at least one sensing line that is simultaneously connected with the plurality of biosensor cells and transmits the sensed signal from one selected from the biosensor cells, and an output terminal that receives the sensed signal from the sensing line and outputs the sensed signal to an external reader. Thus, the biosensor cells are set in array in the biosensor chip without a separate driving unit, so that a process of manufacturing the biosensor chip is simplified. The biosensor cell to be sensed is selectively addressed through the external light, so that it is possible to reduce a price of the biosensor chip used as a disposable chip.

摘要翻译： 提供了一种生物传感器芯片。 生物传感器芯片包括多个生物传感器单元，其被布置在矩阵中并且通过寻址外部光选择性地生成和输出感测信号，至少一个感测线与多个生物传感器单元同时连接并且将感测信号从 从生物传感器单元中选择的一个，以及从感测线接收感测信号并将感测到的信号输出到外部读取器的输出端子。 因此，生物传感器单元在没有单独的驱动单元的情况下被设置在生物传感器芯片中，从而简化了生物传感器芯片的制造工艺。 通过外部光选择性地寻址要感测的生物传感器单元，从而可以降低用作一次性芯片的生物传感器芯片的价格。

公开(公告)号：US20110049401A1

公开(公告)日：2011-03-03

申请号：US12872289

申请日：2010-08-31

申请人： Kwang Hyo CHUNG ,  Yo Han Choi ,  Dae Sik Lee ,  Young Jun Kim ,  Moon Youn Jung ,  Seon Hee Park

发明人： Kwang Hyo CHUNG ,  Yo Han Choi ,  Dae Sik Lee ,  Young Jun Kim ,  Moon Youn Jung ,  Seon Hee Park

IPC分类号： F16K31/08 ,  B21K1/24

CPC分类号： F16K99/0001 ,  F16K99/0015 ,  F16K99/0026 ,  F16K99/0034 ,  F16K99/0046 ,  F16K2099/0078

摘要： There is provided a magnetic microvalve using a metal ball and a method of manufacturing the same. A magnetic microvalve using a metal ball according to an aspect of the invention may include: an upper substrate having a microchannel serving as a passage through which a fluid moves, a fluid inlet through which the fluid flows into the microchannel, and a fluid outlet through which the fluid, having passed through the microchannel, flows out of the microchannel; a lower substrate having a trench locally provided therein; a PDMS/metal ball combination having a metal ball and PDMS surrounding the metal ball so that the metal ball is located in a central portion thereof, the PDMS/metal ball combination being inserted into the trench provided in the lower substrate; and a magnet located above the microchannel, provided in the upper substrate, and generating magnetic force.

摘要翻译： 提供了使用金属球的磁性微型阀及其制造方法。 使用根据本发明的一个方面的金属球的磁性微型阀可以包括：具有作为流体移动通道的微通道的上基板，流体流入微通道的流体入口，以及流体出口通过 已经通过微通道的流体流出微通道; 具有局部设置在其中的沟槽的下基板; 具有围绕金属球的金属球和PDMS的PDMS /金属球组合，使得金属球位于其中心部分，PDMS /金属球组合插入设置在下基板中的沟槽中; 以及设置在上基板上的微通道上方的磁体，并产生磁力。

公开(公告)号：US20100279396A1

公开(公告)日：2010-11-04

申请号：US12746093

申请日：2008-06-27

申请人： Yo Han Choi ,  Kwang Hyo Chung ,  Dae Sik Lee ,  Sang Hee Kim ,  Min Suk Jeong ,  Chi Hoon Jun ,  Moon Youn Jung ,  Seon Hee Park

发明人： Yo Han Choi ,  Kwang Hyo Chung ,  Dae Sik Lee ,  Sang Hee Kim ,  Min Suk Jeong ,  Chi Hoon Jun ,  Moon Youn Jung ,  Seon Hee Park

IPC分类号： C12M3/00 ,  H05K3/00

CPC分类号： C12M23/20 ,  B01L3/5027 ,  B01L7/00 ,  C12M23/16 ,  C12M41/12 ,  Y10T29/49124

摘要： There is provided a cell culture technology for culturing an animal cell in a separate microstructure. The micro-scaled animal cell incubator includes a lower glass substrate having fine hot wires processed with a metal and formed in an upper surface thereof; a first PDMS film attached onto the lower glass substrate to form two or more liquid and solid storage spaces in a position corresponding to the fine hot wires of the lower glass substrate and gas flow channels coupled respectively to the liquid and solid storage spaces to allow generated gases to flow therethrough; a gas-permeable PDMS thin film attached onto the gas flow channels of the PDMS film to pass the generated gases therethrough; a second PDMS film attached onto the PDMS thin film and having a culture medium storage space for storing a culture medium; and an upper glass substrate attached onto the second PDMS film and having fine hot wires formed in a lower surface thereof, the fine hot wires being covered by the PDMS film. The micro-scaled animal cell incubator may be useful to control a temperature of a culture medium to a suitable temperature level, as well as to self-supply gases required for the animal cell culture in a microstructure.

摘要翻译： 提供了用于在单独的微结构中培养动物细胞的细胞培养技术。 微型动物细胞培养箱包括具有用金属加工并形成在其上表面的细微热丝的下玻璃基板; 附着在下玻璃基板上的第一PDMS膜，以形成两个或多个液体和固体存储空间，该液体和固体储存空间位于对应于分别与液体和固体储存空间相连的下玻璃基板和气流通道的细热线的位置，以允许产生 气体流过其中; 透气的PDMS薄膜，附着在PDMS薄膜的气流通道上，以使产生的气体通过; 附着在PDMS薄膜上并具有用于储存培养基的培养基储存空间的第二PDMS膜; 以及附着在第二PDMS膜上并具有形成在其下表面上的精细热丝的上玻璃基板，细的热丝被PDMS膜覆盖。 微量级动物细胞培养箱可用于将培养基的温度控制到合适的温度水平，以及自动供应在微结构中动物细胞培养所需的气体。

公开(公告)号：US20100278694A1

公开(公告)日：2010-11-04

申请号：US12746247

申请日：2008-06-20

申请人： Chul Huh ,  Kyung Hyun Kim ,  Jong Cheol Hong ,  Hyun Sung Ko ,  Wan Joong Kim ,  Gun Yong Sung ,  Seon Hee Park

发明人： Chul Huh ,  Kyung Hyun Kim ,  Jong Cheol Hong ,  Hyun Sung Ko ,  Wan Joong Kim ,  Gun Yong Sung ,  Seon Hee Park

IPC分类号： G01N21/00 ,  H01L21/70

CPC分类号： G01N33/54366

摘要： A silicon biosensor and a manufacturing method thereof is provided, the silicon biosensor includes: a light source performing self emission a light detector generating a photoelectric current corresponding to an amount of incident light an optical fiber transmitting the light from the light source to the light detector and a micro fluidic channel adjusting an optical transmission rate of the optical fiber according to an antibody-antigen reaction when the antibody-antigen reaction occurs. The silicon biosensor can be easily integrated or bonded with a silicon electronic device, so that it is possible to manufacture the biosensor with a low price, under mass production.

摘要翻译： 提供硅生物传感器及其制造方法，所述硅生物传感器包括：光源，其进行自发光，所述光检测器产生与入射光量相对应的光电流，所述光传输光从所述光源传输到所述光检测器 以及当发生抗体 - 抗原反应时根据抗体 - 抗原反应调节光纤的光传输速率的微流体通道。 硅生物传感器可以容易地与硅电子器件集成或结合，使得可以在批量生产的情况下以低价格制造生物传感器。

公开(公告)号：US20100273247A1

公开(公告)日：2010-10-28

申请号：US12746997

申请日：2008-06-24

申请人： Yo Han Choi ,  Monn Youn Jung ,  Seon Hee Park

发明人： Yo Han Choi ,  Monn Youn Jung ,  Seon Hee Park

IPC分类号： C12M1/34

CPC分类号： G01N33/54386 ,  B01L3/5027 ,  B01L2300/0636 ,  B01L2300/0681 ,  B01L2300/0816 ,  B01L2300/0864 ,  B01L2400/0406 ,  B01L2400/0487

摘要： A semi-quantitative immunological detection device with differential antibodies and substrates is provided. The semi-quantitative immunological detection device with differential antibodies, includes: a sample injecting portion through which a sample is injected; and a reaction portion where a plurality of reacting materials reacting with an MUT (material under test) contained in the sample with different sensitivities to generate marker materials are disposed in the same space. Accordingly, a diagnosis result can be visually identified with user's eyes, and the diagnosis result similar to that of a quantitative assay apparatus can be provided.

摘要翻译： 提供了具有差异抗体和底物的半定量免疫检测装置。 具有差异抗体的半定量免疫检测装置包括：注射样品的样品注入部分; 和反应部分，其中多个反应材料与MUT（试验中的材料）反应，具有不同的灵敏度产生标记材料的样品被放置在相同的空间中。 因此，可以用用户的眼睛可视地识别诊断结果，并且可以提供类似于定量测定装置的诊断结果。

公开(公告)号：US20100152763A1

公开(公告)日：2010-06-17

申请号：US12473838

申请日：2009-05-28

申请人： Yark Yeon Kim ,  Won Ick Jang ,  Chang Ho Bae ,  Seon Hee Park ,  Han Young

发明人： Yark Yeon Kim ,  Won Ick Jang ,  Chang Ho Bae ,  Seon Hee Park ,  Han Young

IPC分类号： A61B17/34 ,  A61N2/00

CPC分类号： A61N2/02 ,  A61H39/08 ,  A61N2/002 ,  A61N2/06

摘要： A wireless magnetic needle system for traditional oriental medicine can apply a magnetic field to a needle being used for the acupuncture process on a patient by use of a Helmholtz coil capable of applying a magnetic field to a wide space and can apply a magnetic stimulus to the patient through the needle, thereby making it possible to maximize the therapy effect of the needle. The wireless magnetic needle system includes a current generating unit and a Helmholtz coil. The Helmholtz coil includes a first coaxial coil disposed over a bed for a patient, and a second coaxial coil disposed under the bed. The current generating unit generates a current, and the Helmholtz coil creates a magnetic field by using the current generated by the current generating unit.

摘要翻译： 用于传统东方医学的无线磁针系统可以通过使用能够在宽的空间施加磁场的亥姆霍兹线圈向用于针灸过程的针施加磁场，并且可以向 患者通过针头，从而使得可以使针的治疗效果最大化。 无线磁针系统包括电流发生单元和亥姆霍兹线圈。 亥姆霍兹线圈包括设置在用于患者的床上的第一同轴线圈和设置在床下方的第二同轴线圈。 电流产生单元产生电流，并且亥姆霍兹线圈通过使用由电流发生单元产生的电流产生磁场。

公开(公告)号：US20100142678A1

公开(公告)日：2010-06-10

申请号：US12632746

申请日：2009-12-07

申请人： Nam Soo Myung ,  Nak Woong Eum ,  Seong Mo Park ,  Moon Youn Jung ,  Seon Hee Park

发明人： Nam Soo Myung ,  Nak Woong Eum ,  Seong Mo Park ,  Moon Youn Jung ,  Seon Hee Park

IPC分类号： A61N5/10

CPC分类号： A61N5/10 ,  A61N5/1048 ,  A61N2005/1087

摘要： A minimally invasive particle beam cancer therapy apparatus that can be inserted into the body and deliver a particle beam onto a cancer cell generated in the body. The minimally invasive particle beam cancer therapy apparatus may include: a particle beam delivery system delivering a particle beam onto a diseased part formed inside a therapy subject, the particle beam delivery system being partially inserted into the therapy subject when delivering the particle beam; a medical apparatus body shaped like a pipe having a predetermined length and physically connected to the particle beam delivery system, the medical apparatus being partially inserted into the therapy subject in a longitudinal direction along with the particle beam delivery system being partially inserted into the therapy subject to help the insertion of the particle beam delivery system into the therapy subject; and a control system controlling a driving operation of the particle beam delivery system.

摘要翻译： 一种微创粒子束癌治疗装置，其能够插入体内并将粒子束输送到在体内产生的癌细胞。 微创粒子束癌治疗装置可以包括：粒子束递送系统，其将颗粒束传送到形成在治疗对象内部的病变部分上，所述粒子束递送系统在递送粒子束时部分地插入治疗对象; 形状类似于具有预定长度并且物理连接到粒子束输送系统的管的医疗装置体，所述医疗装置沿着纵向方向部分地插入治疗对象中，并且所述粒子束输送系统被部分插入到治疗对象中 以帮助将粒子束输送系统插入治疗受试者; 以及控制粒子束传送系统的驱动操作的控制系统。