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公开(公告)号：US11563122B2
公开(公告)日：2023-01-24
申请号：US17268628
申请日：2019-08-20
Inventor： Hossam Haick , Muhammad Khatib
IPC: H01L29/786 , H01L29/06 , H01L29/16 , H01L29/24 , H01L29/423 , H01L29/66
Abstract: The present invention provides a self-healing field-effect transistor (FET) device comprising a self-healing substrate and a self-healing dielectric layer, said substrate and said layer comprising a disulfide-containing poly(urea-urethane) (PUU) polymer, wherein the dielectric layer has a thickness of less than about 10 μm, a gate electrode, at least one source electrode, and at least one drain electrode, said electrodes comprising electrically conductive elongated nanostructures; and at least one channel comprising semi-conducting elongated nanostructures. Further provided is a method for fabricating the FET device.
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42.发明申请公开(公告)号：US20220324922A1
公开(公告)日：2022-10-13
申请号：US17851430
申请日：2022-06-28
Inventor： Shai BERLIN , Ido CARMI , Shaden ZOABI
IPC: C07K14/435 , A61K48/00 , A61P25/28
Abstract: Provided herein are modified forms of Conantokin peptides, including, modified Con-P peptides, nucleic acids encoding the same and compositions thereof. Further provided are nucleic acid molecules encoding for chimeric modified conantokin polypeptides to be expressed in or on a membrane of a target cells, compositions comprising the same and uses thereof for treating various neurodegenerative conditions.
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公开(公告)号：US20220307971A1
公开(公告)日：2022-09-29
申请号：US17610863
申请日：2020-05-13
Applicant: Carmel Haifa University Economic Corporation Ltd. , Evogene Ltd. , Elbit Systems Land and C4I Ltd. , Hazera Seeds Ltd. , Opgal Optronics Industries Ltd. , Rahan Meristem (1998) Ltd. , Sensilize Ltd. , The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization , Technion Research and Development Foundation Limited
Inventor： Lior Coen , Victor Alchanatis , Ohsry Markovich , Yoav Zur , Daniel Koster , Yogev Montekyo , Hagai Karchi , Ilya Leizerson , Sharone Aloni , Anna Brook , Zur Granevitze , Yaron Honen , Alon Zvirin , Ron Kimmel
IPC: G01N21/27 , G01N33/02 , G01S17/894 , G01S17/86 , G01N21/25 , G06V10/143 , G06V10/147 , G06V10/80 , G06V10/40 , G06V10/20 , G06T7/30 , H04N5/247 , H04N5/232 , G06V10/774 , G06T7/00 , G06V20/10
Abstract: The present invention relates to the field of phenotyping, particularly to systems and methods for collecting, retrieval and processing of data for accurate and sensitive analysis and prediction of a phenotype of an object, particularly of a plant.
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公开(公告)号：US20220243014A1
公开(公告)日：2022-08-04
申请号：US17613826
申请日：2020-06-04
Inventor： Hossam HAICK , Muhammad KHATIB
IPC: C08G75/14 , G01L1/22 , G01N27/414
Abstract: The present invention provides a solution-processable self-healing hydrolytically stable elastomer, a method for the preparation thereof, and articles of manufacture comprising the elastomer. The elastomer comprises polymeric chains comprising units of formula (A1), wherein R is a polybutadiene-containing polyurethane; R1 and R1′ are independently selected from the group consisting of: —H, (C1-C20)alkyl, (C5-C14)aryl, —OR4, —(CO)R5, —O(CO)R6, —(SO)R7, CO—R8, —COOR9, —NO2, and halogen; R2, R2′, R3 and R3′ are independently selected from the group consisting of: —H, (C1-C20)alkyl, and (C5-C14)aryl; R4 to R9 are the same or different, and are independently selected from the group consisting of: —H, (C1-C20)alkyl, and (C5-C14)aryl; m is 4; wherein the elastomer is dynamically crosslinked by aromatic disulfide metathesis, and wherein the elastomer has a water contact angle of above 100 #.
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公开(公告)号：US20210263050A1
公开(公告)日：2021-08-26
申请号：US17183511
申请日：2021-02-24
Inventor： Hossam HAICK , Yoav BROZA , Mamatha SERASANAMBATI , Dina HASHOUL , Walaa SALIBA
IPC: G01N33/84 , G01N33/574 , G01N30/72
Abstract: The present invention provides methods of detecting cell-to-cell signaling in cancer cells and methods of diagnosing, prognosing and monitoring cancer comprising the use of volatile organic compounds, which are indicative of cell-to-cell signaling in cancer cells.
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Patent Agency Ranking
公开(公告)号：US20210202748A1
公开(公告)日：2021-07-01
申请号：US17268628
申请日：2019-08-20
Inventor： Hossam HAICK , Muhammad KHATIB
IPC: H01L29/786 , H01L29/06 , H01L29/423 , H01L29/16 , H01L29/24 , H01L29/66
Abstract: The present invention provides a self-healing field-effect transistor (FET) device comprising a self-healing substrate and a self-healing dielectric layer, said substrate and said layer comprising a disulfide-containing poly(urea-urethane) (PUU) polymer, wherein the dielectric layer has a thickness of less than about 10 μm, a gate electrode, at least one source electrode, and at least one drain electrode, said electrodes comprising electrically conductive elongated nanostructures; and at least one channel comprising semi-conducting elongated nanostructures. Further provided is a method for fabricating the FET device.
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公开(公告)号：US20210077462A1
公开(公告)日：2021-03-18
申请号：US17025269
申请日：2020-09-18
Inventor： Tomer SHLOMI , Won Dong LEE
IPC: A61K31/4162 , G01N33/574 , A61P35/00
Abstract: The invention provides a method for treating cancer in which a level of reduced folate carrier (RFC) or folylpolyglutamate synthetase (FPGS) in cancer cells of the biopsy is determined. If the level of RFC or FPGS in the cancer cells is below a threshold value, the cancer is treated with an inhibitor of serine-hydroxymethyltransferase (SHMT)1. If the level of RFC or FPGS in the cancer cells is above the threshold value, the cancer is treated with an inhibitor of SHMT2
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公开(公告)号：US09885688B2
公开(公告)日：2018-02-06
申请号：US14555793
申请日：2014-11-28
Inventor： Moran Bercovici , Ortal Schwartz
IPC: G01N27/447
CPC classification number: G01N27/44769 , B01L3/50273 , B01L2200/0652 , B01L2300/06 , B01L2300/0627 , B01L2300/0645 , B01L2300/0816 , B01L2300/0867 , B01L2300/0887 , B01L2300/12 , B01L2400/0421 , B01L2400/043 , B01L2400/0487 , G01N27/44721 , G01N27/44726 , G01N27/44743 , G01N27/44756 , G01N27/44765 , G01N27/44791 , G01N33/561 , G01N33/56911
Abstract: The present invention provides a system including: a protein having a domain that binds a membranal component; an inlet for sample flow, an Isotachophoresis (ITP) system and a flow generating means connected or coupled to the aqueous parts of the ITP. The invention also provides a method for detecting and or sorting cells with this system.
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49.发明申请公开(公告)号：US20150047982A1
公开(公告)日：2015-02-19
申请号：US14461645
申请日：2014-08-18
Inventor： Moran Bercovici , Nadya Ostromohov , Ortal Schwartz
IPC: G01N27/447
CPC classification number: C12Q1/6825 , C12Q1/6816 , G01N27/44726 , G01N27/4473 , G01N27/44765 , G01N27/44791 , C12Q2523/303 , C12Q2525/107 , C12Q2565/607
Abstract: The present invention provides a system including: a peptide nucleic acid (PNA) molecule; a DNA molecule, an RNA molecule, or a combination thereof; and an Isotachophoresis (ITP) system. Furthermore, the invention provides a method for sequence-specifically separating and/or identifying a nucleic acid molecule of interest by utilizing the system of the invention to separate and possibly label and/or detect a nucleic acid molecule of interest.
Abstract translation: 本发明提供一种系统，其包括：肽核酸（PNA）分子; DNA分子，RNA分子或其组合; 和等速电泳（ITP）系统。 此外，本发明提供了通过利用本发明的系统分离和可能标记和/或检测目的核酸分子来序列特异性分离和/或鉴定感兴趣的核酸分子的方法。
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公开(公告)号：US12012342B2
公开(公告)日：2024-06-18
申请号：US17462054
申请日：2021-08-31
Inventor： Matthew E. Suss , Eric N. Guyes , Yinke Chen , Charles E. Diesendruck
IPC: C02F1/469 , C02F1/461 , C02F103/08
CPC classification number: C02F1/4691 , C02F1/46109 , C02F2001/46133 , C02F2001/46138 , C02F2001/46161 , C02F2103/08
Abstract: The present invention relates to a method for selective separation of positively charged monovalent ionic species from an ionic solution. The method comprises passing the ionic solution comprising a positively charged monovalent ion and a positively charged polyvalent ion through an electrode capacitor assembly comprising a first electrode and a second electrode, the electrodes comprising nanoporous carbon, wherein the first electrode is modified with sulfonate surface groups; and at least one flow channel for the passage of the solution. The method further comprises charging the electrode capacitor assembly (1) at a voltage of at least about 1.5 V; and/or (2) for scaled charging time of less than about 2.
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