公开(公告)号：US06681788B2

公开(公告)日：2004-01-27

申请号：US10056219

申请日：2002-01-24

申请人： J. Wallace Parce ,  Andrea W. Chow

发明人： J. Wallace Parce ,  Andrea W. Chow

IPC分类号： F15C118

CPC分类号： F15C1/04 ,  B01L3/02 ,  B01L3/50273 ,  B01L3/502738 ,  B01L2200/0621 ,  B01L2400/0415 ,  B01L2400/0487 ,  B01L2400/06 ,  Y10T137/0396 ,  Y10T137/2076 ,  Y10T137/2142 ,  Y10T137/218 ,  Y10T137/2191 ,  Y10T137/2273

摘要： Methods devices and systems that employ non-mechanical valve modules for controllably directing fluid and other material movement through integrated microscale channel networks. These non-mechanical valve modules apply forces that counter the driving forces existing through a given channel segment, via fluidly connected channel segments, so as to selectively arrest flow of material within the given channel segment.

摘要翻译： 方法使用非机械阀模块的装置和系统，用于可控地引导流体和其他材料运动通过集成的微型通道网络。 这些非机械阀模块通过流体连接的通道段施加抵抗通过给定通道段存在的驱动力的力，以便选择性地阻止给定通道段内的材料流。

公开(公告)号：US08241883B2

公开(公告)日：2012-08-14

申请号：US11412055

申请日：2006-04-25

申请人： Andrea W. Chow ,  John C. Owicki ,  J. Wallace Parce

发明人： Andrea W. Chow ,  John C. Owicki ,  J. Wallace Parce

IPC分类号： C12N13/00

CPC分类号： G01N33/557 ,  B01L3/50273 ,  B01L3/502753 ,  B01L7/52 ,  B01L2200/10 ,  B01L2300/0816 ,  B01L2300/1822 ,  B01L2300/1833 ,  B01L2400/0415 ,  B01L2400/0421 ,  B01L2400/0487 ,  G01N27/44791 ,  G01N33/5306

摘要： The present invention provides novel microfluidic devices and methods for performing pulsed field mobility shift assays in microfluidic devices. In particular the devices and methods of the invention utilize differences between electrophoretic mobilities (e.g., as between reactants and products, especially in non-fluorogenic reactions) in order to separate the species and thus analyze the reaction.

摘要翻译： 本发明提供了用于在微流体装置中进行脉冲场迁移率变动测定的新型微流体装置和方法。 特别地，本发明的装置和方法利用电泳迁移率之间的差异（例如，在反应物和产物之间，特别是在非荧光反应中），以便分离物种并因此分析反应。

公开(公告)号：US6149787A

公开(公告)日：2000-11-21

申请号：US173469

申请日：1998-10-14

申请人： Andrea W. Chow ,  Robert S. Dubrow ,  J. Wallace Parce ,  Steven A. Sundberg ,  Jeffrey A. Wolk

发明人： Andrea W. Chow ,  Robert S. Dubrow ,  J. Wallace Parce ,  Steven A. Sundberg ,  Jeffrey A. Wolk

IPC分类号： B01L3/00 ,  G01N35/00 ,  G01N35/10 ,  G01N27/26

CPC分类号： B01L3/502715 ,  B01L3/502746 ,  B01L2200/027 ,  B01L2300/0816 ,  B01L2300/0838 ,  B01L2300/0867 ,  B01L2400/0406 ,  B01L2400/0415 ,  B01L2400/0487 ,  B01L2400/084 ,  B01L3/50273 ,  G01N2035/00237 ,  G01N2035/1062 ,  Y10S366/02 ,  Y10T436/2575

摘要： Methods, apparatus and systems are provided for introducing large numbers of different materials into a microfluidic analytical device rapidly, efficiently and reproducibly. In particular, improved integrated pipettor chip configurations, e.g. sippers or electropipettors, are described which are capable of sampling extremely small amounts of material for which analysis is desired, transporting material into a microfluidic analytical channel network, and performing the desired analysis on the material.

公开(公告)号：US09683994B2

公开(公告)日：2017-06-20

申请号：US13544006

申请日：2012-07-09

申请人： Andrea W. Chow ,  John C. Owicki ,  J. Wallace Parce

发明人： Andrea W. Chow ,  John C. Owicki ,  J. Wallace Parce

IPC分类号： G01N27/447 ,  G01N33/557 ,  B01L3/00 ,  G01N33/53 ,  B01L7/00

CPC分类号： G01N33/557 ,  B01L3/50273 ,  B01L3/502753 ,  B01L7/52 ,  B01L2200/10 ,  B01L2300/0816 ,  B01L2300/1822 ,  B01L2300/1833 ,  B01L2400/0415 ,  B01L2400/0421 ,  B01L2400/0487 ,  G01N27/44791 ,  G01N33/5306

摘要： The present invention provides novel methods for performing pulsed field mobility shift assays in microfluidic devices. In particular, the methods of the invention utilize differences between electrophoretic mobilities (e.g., as between reactants and products, especially in non-fluorogenic reactions) in order to separate the species and thus analyze the reaction.

公开(公告)号：US07150814B1

公开(公告)日：2006-12-19

申请号：US10214961

申请日：2002-08-08

申请人： J. Wallace Parce ,  Andrea W. Chow

发明人： J. Wallace Parce ,  Andrea W. Chow

IPC分类号： G01N27/453 ,  G01N30/02

CPC分类号： B08B17/00 ,  B01L3/50273 ,  B01L2300/0816 ,  B01L2300/1833 ,  B01L2400/0409 ,  B01L2400/0415 ,  B01L2400/0487 ,  G01N27/44704 ,  G01N27/44752

摘要： Methods and apparatus for reducing adsorption in microscale devices are provided. In the methods and apparatus, an electrical current such as an alternating current is applied to materials under pressure-induced flow. Integrated systems for simultaneous control of current and pressure in a channel are also provided.

公开(公告)号：US20120282540A1

公开(公告)日：2012-11-08

申请号：US13551230

申请日：2012-07-17

申请人： Chunming Niu ,  Calvin Y.H. Chow ,  Stephen A. Empedocles ,  J. Wallace Parce

发明人： Chunming Niu ,  Calvin Y.H. Chow ,  Stephen A. Empedocles ,  J. Wallace Parce

IPC分类号： H01M4/96 ,  H01M8/10

CPC分类号： H01M4/8605 ,  B82Y30/00 ,  H01M4/881 ,  H01M4/8846 ,  H01M4/8853 ,  H01M4/8867 ,  H01M4/90 ,  H01M4/9075 ,  H01M4/921 ,  H01M4/925 ,  H01M4/926 ,  H01M8/023 ,  H01M8/0232 ,  H01M8/0234 ,  H01M8/0236 ,  H01M8/0241 ,  H01M8/1004 ,  H01M8/1007 ,  H01M8/1011 ,  H01M8/1086 ,  Y02E60/523 ,  Y02P70/56 ,  Y10S977/762 ,  Y10S977/948

摘要： The present invention discloses nanowires for use in a fuel cell comprising a metal catalyst deposited on a surface of the nanowires. A membrane electrode assembly for a fuel cell is disclosed which generally comprises a proton exchange membrane, an anode electrode, and a cathode electrode, wherein at least one or more of the anode electrode and cathode electrode comprise an interconnected network of the catalyst supported nanowires. Methods are also disclosed for preparing a membrane electrode assembly and fuel cell based upon an interconnected network of nanowires.

摘要翻译： 本发明公开了一种用于燃料电池的纳米线，其包括沉积在纳米线表面上的金属催化剂。 公开了一种用于燃料电池的膜电极组件，其通常包括质子交换膜，阳极电极和阴极电极，其中阳极电极和阴极电极中的至少一个或多个包括催化剂负载的纳米线的互连网络。 还公开了基于互连的纳米线网络来制备膜电极组件和燃料电池的方法。

公开(公告)号：US08252164B2

公开(公告)日：2012-08-28

申请号：US13113680

申请日：2011-05-23

申请人： Samuel Martin ,  Xiangfeng Duan ,  Katsumasa Fujii ,  James M. Hamilton ,  Hiroshi Iwata ,  Francisco Leon ,  Jeffrey Miller ,  Tetsu Negishi ,  Hiroshi Ohki ,  J. Wallace Parce ,  Cheri X. Y. Pereira ,  Paul John Schuele ,  Akihide Shibata ,  David P. Stumbo ,  Yasunobu Okada

发明人： Samuel Martin ,  Xiangfeng Duan ,  Katsumasa Fujii ,  James M. Hamilton ,  Hiroshi Iwata ,  Francisco Leon ,  Jeffrey Miller ,  Tetsu Negishi ,  Hiroshi Ohki ,  J. Wallace Parce ,  Cheri X. Y. Pereira ,  Paul John Schuele ,  Akihide Shibata ,  David P. Stumbo ,  Yasunobu Okada

IPC分类号： C25D13/02

CPC分类号： H01L29/0665 ,  B82B3/00 ,  B82Y10/00 ,  B82Y30/00 ,  B82Y40/00 ,  H01L29/0673 ,  Y10S977/883

摘要： The present invention provides methods and systems for nanowire alignment and deposition. Energizing (e.g., an alternating current electric field) is used to align and associate nanowires with electrodes. By modulating the energizing, the nanowires are coupled to the electrodes such that they remain in place during subsequent wash and drying steps. The invention also provides methods for transferring nanowires from one substrate to another in order to prepare various device substrates. The present invention also provides methods for monitoring and controlling the number of nanowires deposited at a particular electrode pair, as well as methods for manipulating nanowires in solution.

摘要翻译： 本发明提供了用于纳米线对准和沉积的方法和系统。 使用通电（例如，交流电场）来使纳米线与电极对准和关联。 通过调节激励，纳米线耦合到电极，使得它们在随后的洗涤和干燥步骤期间保持在适当的位置。 本发明还提供了将纳米线从一个衬底转移到另一个衬底以便制备各种器件衬底的方法。 本发明还提供了用于监测和控制在特定电极对上沉积的纳米线的数量的方法，以及用于操纵溶液中的纳米线的方法。

公开(公告)号：US08088483B1

公开(公告)日：2012-01-03

申请号：US11304498

申请日：2005-12-15

申请人： Jeffery A. Whiteford ,  Mihai A. Buretea ,  William P. Freeman ,  J. Wallace Parce ,  Baixin Qian ,  Erik C. Scher

发明人： Jeffery A. Whiteford ,  Mihai A. Buretea ,  William P. Freeman ,  J. Wallace Parce ,  Baixin Qian ,  Erik C. Scher

IPC分类号： B32B5/66

CPC分类号： C07F5/025 ,  B82Y30/00 ,  B82Y40/00 ,  C07F15/0066 ,  Y10T428/2982 ,  Y10T428/2991 ,  Y10T428/2998

摘要： Methods for producing Group 10 metal nanostructures are provided. The methods involve novel precursors, novel surfactants, or novel precursor-surfactant combinations. Compositions related to the methods are also featured.

摘要翻译： 提供了生产第10族金属纳米结构的方法。 所述方法包括新型前体，新型表面活性剂或新型前体 - 表面活性剂组合。 还介绍了与方法相关的组合。

公开(公告)号：US20110165337A1

公开(公告)日：2011-07-07

申请号：US13009675

申请日：2011-01-19

申请人： J. Wallace Parce ,  James M. Hamilton ,  Samuel Martin ,  Erik Freer

发明人： J. Wallace Parce ,  James M. Hamilton ,  Samuel Martin ,  Erik Freer

IPC分类号： B05D1/04 ,  B05B5/025

CPC分类号： B82B3/00 ,  B82Y30/00 ,  B82Y40/00 ,  H01L21/6835 ,  H01L2221/68354 ,  H01L2221/68363

摘要： Methods and systems for applying nanowires and electrical devices to surfaces are described. In a first aspect, at least one nanowire is provided proximate to an electrode pair. An electric field is generated by electrodes of the electrode pair to associate the at least one nanowire with the electrodes. The electrode pair is aligned with a region of the destination surface. The at least one nanowire is deposited from the electrode pair to the region. In another aspect, a plurality of electrical devices is provided proximate to an electrode pair. An electric field is generated by electrodes of the electrode pair to associate an electrical device of the plurality of electrical devices with the electrodes. The electrode pair is aligned with a region of the destination surface. The electrical device is deposited from the electrode pair to the region.

摘要翻译： 描述了将纳米线和电气装置应用于表面的方法和系统。 在第一方面，在电极对附近提供至少一个纳米线。 由电极对的电极产生电场，以将至少一个纳米线与电极相关联。 电极对与目的地表面的区域对准。 将至少一个纳米线从电极对沉积到该区域。 在另一方面，在电极对附近提供多个电气装置。 由电极对的电极产生电场，以将多个电气装置中的电气装置与电极相关联。 电极对与目的地表面的区域对准。 电器件从电极对沉积到该区域。

公开(公告)号：US07968474B2

公开(公告)日：2011-06-28

申请号：US11979949

申请日：2007-11-09

申请人： Samuel Martin ,  Xiangfeng Duan ,  Katsumasa Fujii ,  James M. Hamilton ,  Hiroshi Iwata ,  Francisco Leon ,  Jeffrey Miller ,  Tetsu Negishi ,  Hiroshi Ohki ,  J. Wallace Parce ,  Cheri X. Y. Pereira ,  Paul John Schuele ,  Akihide Shibata ,  David P. Stumbo ,  Yasunobu Okada

发明人： Samuel Martin ,  Xiangfeng Duan ,  Katsumasa Fujii ,  James M. Hamilton ,  Hiroshi Iwata ,  Francisco Leon ,  Jeffrey Miller ,  Tetsu Negishi ,  Hiroshi Ohki ,  J. Wallace Parce ,  Cheri X. Y. Pereira ,  Paul John Schuele ,  Akihide Shibata ,  David P. Stumbo ,  Yasunobu Okada

IPC分类号： H01L21/71

CPC分类号： H01L29/0665 ,  B82B3/00 ,  B82Y10/00 ,  B82Y30/00 ,  B82Y40/00 ,  H01L29/0673 ,  Y10S977/883

摘要： The present invention provides methods and systems for nanowire alignment and deposition. Energizing (e.g., an alternating current electric field) is used to align and associate nanowires with electrodes. By modulating the energizing, the nanowires are coupled to the electrodes such that they remain in place during subsequent wash and drying steps. The invention also provides methods for transferring nanowires from one substrate to another in order to prepare various device substrates. The present invention also provides methods for monitoring and controlling the number of nanowires deposited at a particular electrode pair, as well as methods for manipulating nanowires in solution.

摘要翻译： 本发明提供了用于纳米线对准和沉积的方法和系统。 使用通电（例如，交流电场）来使纳米线与电极对准和关联。 通过调节激励，纳米线耦合到电极，使得它们在随后的洗涤和干燥步骤期间保持在适当的位置。 本发明还提供了将纳米线从一个衬底转移到另一个衬底以便制备各种器件衬底的方法。 本发明还提供了用于监测和控制在特定电极对上沉积的纳米线的数量的方法，以及用于操纵溶液中的纳米线的方法。