公开(公告)号：US20120143228A1

公开(公告)日：2012-06-07

申请号：US13340331

申请日：2011-12-29

申请人： Sriram Natarajan ,  Joseph J. Hammer ,  Kevin Cooper ,  Murty N. Vyakarnam ,  Hong Yee Low ,  Isabel Rodriguez ,  Chee Tiong Lim ,  Audrey Yoke Yee Ho

发明人： Sriram Natarajan ,  Joseph J. Hammer ,  Kevin Cooper ,  Murty N. Vyakarnam ,  Hong Yee Low ,  Isabel Rodriguez ,  Chee Tiong Lim ,  Audrey Yoke Yee Ho

IPC分类号： A61B17/03 ,  B29C70/00

CPC分类号： A61F2/0063 ,  A61B2017/00871 ,  A61B2017/00938 ,  A61B2017/00942 ,  A61B2017/00951 ,  A61L31/048 ,  A61L31/06 ,  A61L31/10 ,  B29C33/52 ,  C09J7/21 ,  C09J7/30 ,  C09J2201/32 ,  C09J2400/263 ,  C08L23/12 ,  C08L67/04

摘要： A laminate and process of making the laminate is disclosed comprising: a surgical mesh having first and second surfaces; and an adhesive structure having adhesive and non-adhesive surfaces, wherein the non-adhesive surface of the adhesive structure is laminated to at least one of said first and second surfaces of said surgical mesh, and the adhesive surface of said adhesive structure has protrusions extending therefrom comprising a resin having a Young's modulus of greater than 17 MPa, which protrusions are of sufficiently low diameter to promote adhesion by increasing physical attractive forces between the adhesive structure and a target surface, as measured by shear adhesion.

摘要翻译： 公开了层压体和制造层压体的方法，包括：具有第一和第二表面的外科手术网; 以及具有粘合剂和非粘合剂表面的粘合剂结构，其中粘合剂结构的非粘合表面被层压到所述外科手术网的所述第一和第二表面中的至少一个上，并且所述粘合剂结构的粘合剂表面具有延伸的突起 其包含杨氏模量大于17MPa的树脂，该突起的直径足够小，以通过剪切粘合力测量来增加粘合剂结构和目标表面之间的物理吸引力来促进粘合。

公开(公告)号：US08137322B2

公开(公告)日：2012-03-20

申请号：US11880499

申请日：2007-07-23

申请人： Michael A. Soltz ,  Megan L. Prommersberger ,  Richard D. Gresham

发明人： Michael A. Soltz ,  Megan L. Prommersberger ,  Richard D. Gresham

IPC分类号： A61M5/32

CPC分类号： A61B17/3417 ,  A61B2017/00898 ,  A61B2017/00942 ,  A61B2017/3419 ,  A61B2017/3484

摘要： A stabilizer is provided to secure and fix the position of a cannula assembly relative to tissue. The stabilizer is a liquid swellable member which expands within an incision in tissue in response to the absorption of a liquid. The stabilizer includes an inner adhesive layer to secure the stabilizer relative to a cannula assembly. The stabilizer is formed of a polymeric gel or foam. In one embodiment, the stabilizer is fixedly secured to an elongate tubular member of a cannula assembly. In an alternative embodiment, the stabilizer is mounted for longitudinal movement along an elongate tubular member of a cannula assembly.

摘要翻译： 提供稳定器以固定和固定插管组件相对于组织的位置。 稳定剂是液体可膨胀的构件，其响应于液体的吸收而在组织内的切口内膨胀。 稳定器包括内部粘合剂层，以相对于插管组件固定稳定器。 稳定剂由聚合物凝胶或泡沫形成。 在一个实施例中，稳定器固定地固定到套管组件的细长管状构件上。 在替代实施例中，稳定器被安装成沿着套管组件的细长管状构件纵向移动。

公开(公告)号：US20120052234A1

公开(公告)日：2012-03-01

申请号：US12871745

申请日：2010-08-30

申请人： Sriram NATARAJAN ,  Kevin COOPER ,  Noha ELMOUELHI ,  Murty N. VYAKARNAM ,  Hong Yee LOw ,  Isabel RODRIGUEZ ,  Chee Tiong LIM ,  Audrey Yoke Yee HO

发明人： Sriram NATARAJAN ,  Kevin COOPER ,  Noha ELMOUELHI ,  Murty N. VYAKARNAM ,  Hong Yee LOw ,  Isabel RODRIGUEZ ,  Chee Tiong LIM ,  Audrey Yoke Yee HO

IPC分类号： B32B3/06 ,  B28B7/34 ,  G01B5/28

CPC分类号： C09J7/00 ,  A61B2017/00871 ,  A61B2017/00938 ,  A61B2017/00942 ,  A61B2017/00951 ,  A61L24/0042 ,  A61L24/046 ,  A61L24/06 ,  A61L24/106 ,  B29C33/424 ,  B29C33/52 ,  C09J2201/626 ,  C09J2423/106 ,  C09J2467/006 ,  Y10T428/24008 ,  C08L67/04 ,  C08L23/12

摘要： An adhesive structure is provided comprising a surface from which extend substantially cylindrical protrusions comprising a stiff resin having a Young's modulus of greater than 17 MPa. The protrusions are of sufficiently low diameter to promote adhesion by physical attractive forces, e.g., Van der Waals attractive forces, as measured by shear adhesion between the adhesive structure and a target surface. A method for preparing the structure is provided as well as a combination of the adhesive structure and target surface.

摘要翻译： 提供了一种粘合剂结构，其包括表面，从该表面延伸出基本上圆柱形的突起，其包括具有大于17MPa的杨氏模量的刚性树脂。 突起具有足够低的直径，以通过物理吸引力（例如，通过粘合剂结构和目标表面之间的剪切粘合力测量的范德华力吸引力）来促进粘附。 提供了制备该结构的方法以及粘合剂结构和目标表面的组合。

公开(公告)号：US20110295316A1

公开(公告)日：2011-12-01

申请号：US12974414

申请日：2010-12-21

申请人： Richard S. Ginn ,  Nicanor Domingo ,  Hans F. Valencia ,  Robert Elliott DeCou ,  Scott Yerby

发明人： Richard S. Ginn ,  Nicanor Domingo ,  Hans F. Valencia ,  Robert Elliott DeCou ,  Scott Yerby

IPC分类号： A61B17/03

CPC分类号： A61B17/0057 ,  A61B2017/00592 ,  A61B2017/00597 ,  A61B2017/0061 ,  A61B2017/00659 ,  A61B2017/00663 ,  A61B2017/00672 ,  A61B2017/00867 ,  A61B2017/00942 ,  A61F2/82 ,  A61F2/95 ,  A61F2/954 ,  A61F2/966 ,  A61F2002/823 ,  A61F2002/9534

摘要： Embodiments are described for closing vascular access ports, such as arteriotomies, which involve placement and deployment of an expandable device configured to prevent blood flow across a subject arteriotomy while also keeping disturbance of intravascular flow to a minimum. Suitable prostheses may comprise one or more frames constructed from lengths of flexible materials, such as shape memory alloys or polymers. Such frames may be coupled to sheetlike or tube-like structures configured to spread loads, minimize thrombosis which may be related to intravascular flow, and maintain hemostasis.

摘要翻译： 描述了用于关闭血管进入端口（例如动脉切开术）的实施例，其涉及可扩张装置的放置和展开，所述可扩张装置被配置为防止血流穿过对象动脉切开术，同时将血管内流动紊乱保持最小。 合适的假体可以包括由诸如形状记忆合金或聚合物的柔性材料的长度构成的一个或多个框架。 这样的框架可以耦合到片状或管状结构，其构造成扩展负载，使可能与血管内流动相关的血栓形成最小化并且保持止血。

公开(公告)号：US20110152788A1

公开(公告)日：2011-06-23

申请号：US12944184

申请日：2010-11-11

申请人： Joseph Hotter

发明人： Joseph Hotter

IPC分类号： A61M5/00

CPC分类号： A61B17/3439 ,  A61B17/0218 ,  A61B17/3421 ,  A61B17/3423 ,  A61B17/3431 ,  A61B17/3462 ,  A61B17/3498 ,  A61B2017/00942 ,  A61B2017/0225 ,  A61B2017/3419 ,  A61B2017/3441 ,  A61B2017/3486

摘要： A cannula assembly includes a cannula adapted for insertion within tissue and having a longitudinal passage extending along a longitudinal axis of the cannula for passage of a surgical instrument. An expandable member is mounted to the cannula and longitudinally spaced from a distal end of the cannula. The expandable member is adapted to expand, upon introduction of fluids therein, in a radially outward direction relative to the longitudinal axis whereby the expandable member engages the tissue to facilitate anchoring of the cannula relative to the tissue, and also to expand in a radially inward direction relative to the longitudinal axis and within the longitudinal passage to engage the surgical instrument positioned within the longitudinal passage to facilitate formation of a seal about the surgical instrument.

摘要翻译： 插管组件包括适于插入组织内并具有沿插管的纵向轴线延伸以便外科器械通过的纵向通道的套管。 可扩张构件安装到套管并且与插管的远端纵向间隔开。 可膨胀构件适于在其中引入流体时在相对于纵向轴线的径向向外的方向上膨胀，由此可扩张构件接合组织以便于套管相对于组织的锚固，并且还可径向向内扩张 方向相对于纵向轴线并且在纵向通道内以接合定位在纵向通道内的手术器械，以便于围绕手术器械形成密封。

公开(公告)号：US12075993B2

公开(公告)日：2024-09-03

申请号：US18107402

申请日：2023-02-08

申请人： Sulaiman Abdulmohsin Almalaq

发明人： Sulaiman Abdulmohsin Almalaq

IPC分类号： A61B17/00 ,  A61L31/04 ,  A61L31/14

CPC分类号： A61B17/00 ,  A61L31/042 ,  A61L31/048 ,  A61L31/148 ,  A61B2017/00004 ,  A61B2017/00526 ,  A61B2017/00752 ,  A61B2017/00876 ,  A61B2017/00942

摘要： A soluble needle (100) for hair transplantation, wherein the soluble needle (100) comprises a fixing plate (30) and a plurality of micro-needles (20) made of water-soluble polymers arranged on the fixing plate (30), wherein each of said micro-needle (20) comprises a needle wall (21) to penetrate scalps and a needle cavity (22) confined by the needle wall (21) and configured for accommodating a hair follicle. A method of manufacturing a soluble needle (100) for hair transplantation, wherein the method includes: dissolving water-soluble polymers in water to prepare a molding solution (S101); delivering the molding solution into a mold (S102); letting the molding solution settle in the mold to shape (S103); and separating and removing the mold to produce the soluble needle (S104). The soluble needle (100) effectively shortens the time of surgery, reduces the pain of the patients, and increases the viability rate of transplanted hair follicles.

公开(公告)号：US20240197336A1

公开(公告)日：2024-06-20

申请号：US18587736

申请日：2024-02-26

申请人： MicroVention, Inc.

发明人： Aaron Baldwin ,  Ami Mehta ,  Jonathan Lam

IPC分类号： A61B17/12 ,  A61B17/00 ,  A61B90/00 ,  A61K31/785 ,  A61K49/04 ,  C08F20/26 ,  C08L33/14

CPC分类号： A61B17/12181 ,  A61B17/12186 ,  A61K31/785 ,  A61K49/0438 ,  A61K49/0442 ,  C08F20/26 ,  A61B2017/00938 ,  A61B2017/00942 ,  A61B2090/3933 ,  A61B2090/3966 ,  C08L33/14

摘要： Described herein are compositions comprising, a polymer, a non-physiological solution; and a visualization agent; wherein the polymer is soluble in the non-physiological solution and insoluble at physiological conditions. Methods of preparing the compositions are disclosed as well as methods of using these compositions to treat vascular conditions.

公开(公告)号：US20230355835A1

公开(公告)日：2023-11-09

申请号：US18199694

申请日：2023-05-19

申请人： BAXTER INTERNATIONAL INC. ,  BAXTER HEALTHCARE SA

发明人： John Barry ,  Paul Sanders ,  Rahul Singh ,  Krishnakumarsinh H. Parmar ,  Ben Ko ,  Stephanie Klunk

IPC分类号： A61L26/00 ,  A61M35/00 ,  A61B17/00

CPC分类号： A61L26/0038 ,  A61L26/008 ,  A61M35/003 ,  A61L26/009 ,  A61L26/0033 ,  A61L26/0023 ,  A61B17/00491 ,  A61L26/0042 ,  A61L26/0047 ,  A61L2400/04 ,  A61B2017/00942 ,  A61B2017/00898 ,  A61M5/2033

摘要： Polymeric compositions, methods, and delivery devices for inhibiting bleeding are disclosed. The method includes applying a dried material topically to a wound site, where the material may include a cross-linked biologically compatible polymer which forms a hydrogel when exposed to blood and where the material may not include an active agent such as thrombin. A spring-loaded delivery device as described herein may be used to apply the dried material.

公开(公告)号：US11793509B2

公开(公告)日：2023-10-24

申请号：US17213530

申请日：2021-03-26

申请人： Cilag GmbH International

发明人： Chester O. Baxter, III ,  Frederick E. Shelton, IV ,  Jeffrey S. Swayze ,  Taylor W. Aronhalt ,  Katherine J. Schmid

IPC分类号： A61B17/064 ,  A61B17/072 ,  A61B17/115 ,  A61B17/068 ,  A61B17/10 ,  A61B17/00 ,  A61B17/29 ,  A61B90/00 ,  A61B17/32

CPC分类号： A61B17/0643 ,  A61B17/00491 ,  A61B17/068 ,  A61B17/0644 ,  A61B17/072 ,  A61B17/07207 ,  A61B17/07292 ,  A61B17/105 ,  A61B17/1155 ,  A61B17/0682 ,  A61B17/2909 ,  A61B2017/00004 ,  A61B2017/0053 ,  A61B2017/00314 ,  A61B2017/00327 ,  A61B2017/00526 ,  A61B2017/00561 ,  A61B2017/00818 ,  A61B2017/00862 ,  A61B2017/00884 ,  A61B2017/00889 ,  A61B2017/00893 ,  A61B2017/00898 ,  A61B2017/00938 ,  A61B2017/00942 ,  A61B2017/0641 ,  A61B2017/0725 ,  A61B2017/07228 ,  A61B2017/07235 ,  A61B2017/07242 ,  A61B2017/07257 ,  A61B2017/07264 ,  A61B2017/07271 ,  A61B2017/07278 ,  A61B2017/07285 ,  A61B2017/2908 ,  A61B2017/2919 ,  A61B2017/2923 ,  A61B2017/2927 ,  A61B2017/2933 ,  A61B2017/2936 ,  A61B2017/2937 ,  A61B2017/320052 ,  A61B2090/0807

摘要： A tissue thickness compensator can comprise a compensator body and at least one vessel contained in the compensator body. The vessel can define an inner cavity which can comprise an inner atmosphere having a pressure which is lower than the atmospheric pressure of the atmosphere surrounding the tissue thickness compensator. In at least one embodiment, the vessel and the compensator body can be maintained in a collapsed state until staples are fired through the vessel. At such point, the vessel can re-expand and apply a biasing force to tissue captured within the staples.

公开(公告)号：US11786255B2

公开(公告)日：2023-10-17

申请号：US17175037

申请日：2021-02-12

申请人： Neurogami Medical, Inc.

发明人： Stephen J. Hebert ,  Bartosz Bojanowski

IPC分类号： A61B17/12 ,  A61F2/00 ,  A61B17/00 ,  A61F2/82 ,  A61F2/90 ,  A61F2/07 ,  A61F2/06

CPC分类号： A61B17/12118 ,  A61B17/1215 ,  A61B17/12031 ,  A61B17/12172 ,  A61F2/0095 ,  A61B17/0057 ,  A61B17/12145 ,  A61B17/12163 ,  A61B17/12177 ,  A61B2017/0053 ,  A61B2017/00526 ,  A61B2017/00893 ,  A61B2017/00898 ,  A61B2017/00942 ,  A61B2017/12054 ,  A61F2/06 ,  A61F2/07 ,  A61F2/90 ,  A61F2002/823 ,  A61F2210/0076 ,  A61F2230/0067 ,  A61F2230/0091

摘要： A packaging for an implant to hold the implant in a first condition. The packaging including a first packaging tube and a container, wherein the implant is movable from the container into the first tube and maintained within the first tube in a second condition, the implant having a first transverse dimension in the first condition and a second transverse dimension in the second condition, the second transverse dimension being less than the first transverse dimension.