摘要:
A unitary package for water treatment for attachment to a home hot water heater, boiler and the like which is adapted to be easily serviced and installed by the home owner. The water treatment device is constructed to provide free and unobstructed flow of water with no restriction and provides a long-lasting life with very little maintenance. The water treatment device comprises an electromagnetic coil energized by D.C. which completely encircles a control conduit pipe. This pipe is provided at the inlet thereof with a T-shaped fitting having an inlet; the pipe is also provided at the outlet thereof with a similar T-shaped fitting having an outlet. Each of the T-shaped fittings is provided with a male plug at opposing ends for supporting a bearing bushing beyond the inlet and outlet openings of the T-shaped fittings. Each of the bearing bushings supports a solid helical impeller and shaft which rotates only when water flows through the central pipe. The impeller is made of stainless steel (ferromagnetic) and is fitted to a very close tolerance to the wall of the central pipe thereby sweeping in a broom fashion the inner wall free from particles which tend to deposit on the wall when the electromagnetic coil is energized. Since the bearing bushings are outside of the flow line of water, they do not obstruct the free flow of water and are so constructed to provide a long-lasting life.
摘要:
The method of concentrating magnetic ore consists of forcing a fluid medium to flow along guides having curved and rectilinear portions; and directing the flow by a pulsating magnetic flux, so that the heavy magnetic particles are forced towards the outer side of the guides. Less heavy particles of the nonmagnetic fraction are washed away by the flow of a fluid medium. In the curved portions of the guides, the magnetic flux coincides in direction with the centrifugal force; in the rectilinear portions of the guides, there is no centrifugal force and the magnetic flux is directed at right angles to the flow of the ore to be concentrated. The magnetic centrifugal separator includes and air-tight housing having curved portions alternating with rectilinear portions. Sources of magnetic flux are located on these portions of the housing. Means are provided to cause the magnetic flux to pulsate.
摘要:
A continuous flow magnetic separator is disclosed for classifying magnetic and paramagnetic particles as concentrate from their mixture with ambient tailings. The separator includes a helical classifying path interior of a non-magnetic, non-conductive conduit, with the conduit wound along a path having an "uphill-downhill" slope with respect to the ambient gravitational bias. A magnetic field (preferably generated by an AC or DC energized coil) is aligned substantially coincident to the axis of generation of the helical path. This magnetic field is confined interior of a high permeability (preferably laminated) magnetic field conducting core having two elements. The first element, to which the coil is attached, is an outer cylindrical conductor (preferably closed at the bottom) defining interiorly thereof a cylindrically shaped inner volume. The second element is a cylindrical rotor having serrated edges and mounted for rotation about the axis of the helical path. The rotor defines between the outer cylindrical conductor and its rotating serrated edges a cylindrical gap into which the helical classifying conduit is placed. Particles to be classified are placed into the helical classifying conduit medially between the concentrate output at the upper end of the helix and the tailings output at the lower end of the helix. Upon rotation of the rotor to wind the magnetic and paramagnetic particles "uphill", a concentrated magnetic field at the serrated edges winds the magnetic concentrate in the helical classifying path to the concentrate output. The tailings move in opposition to the concentrate, gravitationally moving on the downhill slope of the helix through the conduit to the tailings output.
摘要:
A computational cytometer operates using magnetically modulated lensless speckle imaging, which introduces oscillatory motion to magnetic bead-conjugated rare cells of interest through a periodic magnetic force and uses lensless time-resolved holographic speckle imaging to rapidly detect the target cells in three-dimensions (3D). Detection specificity is further enhanced through a deep learning-based classifier that is based on a densely connected pseudo-3D convolutional neural network (P3D CNN), which automatically detects rare cells of interest based on their spatio-temporal features under a controlled magnetic force. This compact, cost-effective and high-throughput computational cytometer can be used for rare cell detection and quantification in bodily fluids for a variety of biomedical applications.
摘要:
A method for magnetic cellular manipulation may include contacting a composition with a biological sample to form a mixture. The composition may include a plurality of particles. Each particle in the plurality of particles may include a magnetic substrate. The magnetic substrate may be characterized by a magnetic susceptibility greater than zero. The composition may also include a chargeable silicon-containing compound. The chargeable silicon-containing compound may coat at least a portion of the magnetic substrate. The biological sample may include cells and/or cellular structures. The method may also include applying a magnetic field to the mixture to manipulate the composition.
摘要:
An internal assembly (230) for a tool (200) includes a retainer (232) that at least partially defines an axial bore (238). The retainer (232) further defines a port (246) providing a path of fluid communication from an exterior of the retainer to the bore (238). The internal assembly (230) also includes an electromagnet (250) coupled to the retainer (232). The electromagnet (250) is configured to actuate between an on state and an off state and to attract magnetic debris in a fluid when in the on state. The internal assembly (230) also includes a sleeve (260) that is configured to be positioned downstream from the retainer (232). The sleeve (260) at least partially defines the bore (238). The sleeve (260) further defines a port (262) that provides a path of fluid communication from the bore (238) to an exterior of the sleeve (260). The internal assembly (230) also includes a valve (270) configured to be positioned downstream from the port (262) in the sleeve (260).
摘要:
The invention relates to bead incubating and washing on a droplet actuator. Methods for incubating magnetically responsive beads that are labeled with primary antibody, a sample (i.e., analyte), and secondary reporter antibodies on a magnet, on and off a magnet, and completely off a magnet are provided. Also provided are methods for washing magnetically responsive beads using shape-assisted merging of droplets. Also provided are methods for shape-mediated splitting, transporting, and dispensing of a sample droplet that contains magnetically responsive beads. The apparatuses and methods of the invention provide for rapid time to result and optimum detection of an analyte in an immunoassay.