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    Nerve stimulator system
    61.
    发明授权
    Nerve stimulator system 有权

    公开(公告)号：US09656074B2

    公开(公告)日：2017-05-23

    申请号：US14959183

    申请日：2015-12-04

    申请人： ElectroCore, LLC

    发明人： Bruce J. Simon ,  Joseph P. Errico ,  Steven Mendez

    IPC分类号： A61N1/00 ,  A61N1/36 ,  A61N1/375 ,  A61N1/378 ,  A61N1/372

    CPC分类号： A61N1/36053 ,  A61N1/3605 ,  A61N1/36153 ,  A61N1/36171 ,  A61N1/36175 ,  A61N1/37205 ,  A61N1/37223 ,  A61N1/3756 ,  A61N1/3787

    摘要： Devices, systems and methods for treating at least one of a condition or a symptom of a patient by positioning a stimulation device at a target site adjacent to or near a nerve within a patient. The stimulation device comprising an antenna and one or more electrodes. Transmitting electrical energy to the antenna and generating electrical impulses within the stimulation device with the electrical energy and applying the series of electrical impulses to the nerve via the electrode. The electrical impulses sufficient to modulate the nerve and treat the condition or symptom of the patient; and which have on periods where the electrical impulses are generated and applied to the nerve and off periods between the electrical impulses, where the electrical energy is transmitted to the antenna.

    Methods and systems for employing a duty cycle in electrical stimulation of patient tissue
    62.
    发明授权
    Methods and systems for employing a duty cycle in electrical stimulation of patient tissue 有权

    公开(公告)号：US09643010B2

    公开(公告)日：2017-05-09

    申请号：US14572606

    申请日：2014-12-16

    申请人： BOSTON SCIENTIFIC NEUROMODULATION CORPORATION

    发明人： Emarit A. S. Ranu

    IPC分类号： A61N1/36 ,  A61N1/02 ,  A61N1/05

    CPC分类号： A61N1/36175 ,  A61N1/025 ,  A61N1/0553 ,  A61N1/36 ,  A61N1/3615

    摘要： A method of delivering electrical stimulation energy includes receiving stimulation parameters such as a selection of one or more electrodes, a stimulation amplitude, and a stimulation frequency. The stimulation parameters define, at least in part, an electrical stimulation energy deliverable as a series of electrical pulses at the stimulation frequency. The method also includes receiving a duty cycle parameter that indicates a relative number of the electrical pulses to be suppressed; and delivering the electrical stimulation energy to patient tissue through the stimulation lead. A percentage of the electrical pulses are suppressed according to the duty cycle parameter. Optionally, a distribution parameter is received that indicates how suppressed electrical pulses are to be distributed among the electrical pulses. Optionally, a suppression level parameter is received that indicates a reduction of the stimulation amplitude for each electrical pulse that is to be suppressed.

    Intermittent neural stimulation with physiologic response monitor
    63.
    发明授权
    Intermittent neural stimulation with physiologic response monitor 有权

    公开(公告)号：US09623255B2

    公开(公告)日：2017-04-18

    申请号：US14218092

    申请日：2014-03-18

    申请人： Cardiac Pacemakers, Inc.

    发明人： Imad Libbus

    IPC分类号： A61N1/32 ,  A61N1/372 ,  A61N1/36

    CPC分类号： A61N1/36139 ,  A61N1/36114 ,  A61N1/36117 ,  A61N1/36175 ,  A61N1/36178 ,  A61N1/37264

    摘要： Various aspects of the present subject matter provide an implantable medical device. In various embodiments, the device comprises a pulse generator, a first monitor and a controller. The pulse generator is adapted to generate a neural stimulation signal for a neural stimulation therapy. The neural stimulation signal has at least one adjustable parameter. The first monitor is adapted to detect an undesired effect. In some embodiments, the undesired effect is myocardial infarction. The controller is adapted to respond to the first monitor and automatically adjust the at least one adjustable parameter of the neural stimulation signal to avoid the undesired effect of the neural stimulation therapy. Other aspects are provided herein.

    SYSTEMS, DEVICES AND METHODS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS AND CONDITIONS
    67.
    发明申请
    SYSTEMS, DEVICES AND METHODS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS AND CONDITIONS 审中-公开
    用于治疗神经病学和病症的系统，装置和方法

    公开(公告)号：US20170028198A1

    公开(公告)日：2017-02-02

    申请号：US15295160

    申请日：2016-10-17

    申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

    发明人： Christopher M. Degiorgio ,  Patrick Miller

    IPC分类号： A61N1/36 ,  A61N1/05 ,  A61N1/04

    CPC分类号： A61N1/36082 ,  A61N1/0456 ,  A61N1/0476 ,  A61N1/0492 ,  A61N1/0504 ,  A61N1/0529 ,  A61N1/0551 ,  A61N1/36014 ,  A61N1/36021 ,  A61N1/36025 ,  A61N1/36064 ,  A61N1/36067 ,  A61N1/36075 ,  A61N1/36096 ,  A61N1/36157 ,  A61N1/3616 ,  A61N1/36171 ,  A61N1/36175

    摘要： The present disclosure relates to methods, devices, and systems used for the treatment of and/or promoting recovery from various neurological disorders and conditions, including epilepsy and other seizure disorders and movement and other related disorders; for promoting recovery from acute or chronic brain injury (e.g. stroke, hypoxia/ischemia, head trauma, subarachnoid hemorrhage, and other forms of brain injury, for awakening and/or promoting the recovery of patients in various levels of coma, altered mental status or vegetative state); or for promoting recovery from chronic daily headache and migraine and related disorders via external (cutaneous) stimulation of the sensory branches of the trigeminal nerve in the face and forehead. More specifically, devices and electrode assemblies configured for stimulation of the supraorbital, supratrochlear, infraorbital, auriculotemporal, zygomaticotemporal, zygomaticoorbital, zygomaticofacial, nasal and infratrochlear nerves are disclosed.

    摘要翻译： 本公开涉及用于治疗和/或促进从各种神经障碍和病症恢复的方法，装置和系统，包括癫痫和其他癫痫发作障碍以及运动和其它相关疾病; 用于促进急性或慢性脑损伤（例如中风，缺氧/缺血，头部创伤，蛛网膜下腔出血和其他形式的脑损伤）的恢复，用于唤醒和/或促进各种昏迷水平的患者的恢复，改变的精神状态或 营养状态）; 或通过外部（皮肤）刺激面部和额头中三叉神经的感觉分支来促进慢性日常头痛和偏头痛及相关疾病的恢复。 更具体地，公开了被配置用于刺激眶上，眶上，眶下，z骨，z骨，z骨，z骨，鼻和神经性神经的装置和电极组件。

    IMPLANT TOOL AND IMPROVED ELECTRODE DESIGN FOR MINIMALLY INVASIVE PROCEDURE
    68.
    发明申请
    IMPLANT TOOL AND IMPROVED ELECTRODE DESIGN FOR MINIMALLY INVASIVE PROCEDURE 审中-公开
    嵌入式工具和改进的电极设计，用于最小的入侵程序

    公开(公告)号：US20170007826A1

    公开(公告)日：2017-01-12

    申请号：US15251239

    申请日：2016-08-30

    申请人： CVRx, Inc.

    发明人： Adam Cates ,  Eric Lovett ,  Loren Murney ,  Kip Ludwig ,  Paul Pignato ,  Brian Soltis

    IPC分类号： A61N1/05 ,  A61N1/36

    CPC分类号： A61N1/05 ,  A61N1/0558 ,  A61N1/36117 ,  A61N1/36139 ,  A61N1/36157 ,  A61N1/36171 ,  A61N1/36175 ,  A61N1/36182

    摘要： Devices and methods of use for introduction and implantation of an electrode as part of a minimally invasive technique. An implantable baroreflex activation system includes a control system having an implantable housing, an electrical lead, attachable to the control system, and an electrode structure. The electrode structure is near one end of the electrical lead, and includes a monopolar electrode, a backing material having an effective surface area larger than the electrode, and a releasable pivotable interface to mate with an implant tool. The electrode is configured for implantation on an outer surface of a blood vessel and the control system is programmed to deliver a baroreflex therapy via the monopolar electrode to a baroreceptor within a wall of the blood vessel.

    摘要翻译： 用于引入和植入电极作为微创技术的一部分的装置和方法。 可植入压力反射激活系统包括具有可植入壳体，可引导到控制系统的电引线和电极结构的控制系统。 电极结构靠近电引线的一端，并且包括单极电极，具有大于电极的有效表面积的背衬材料以及与植入工具配合的可释放的可枢转接口。 电极被配置为植入在血管的外表面上，并且控制系统被编程为通过单极电极将压力反射治疗递送到血管壁内的压力感受器。

    Fractionalized Stimulation Pulses in an Implantable Stimulator Device
    69.
    发明申请
    Fractionalized Stimulation Pulses in an Implantable Stimulator Device 审中-公开
    可植入刺激装置中的分数化刺激脉冲

    公开(公告)号：US20170001019A1

    公开(公告)日：2017-01-05

    申请号：US15210726

    申请日：2016-07-14

    申请人： Boston Scientific Neuromodulation Corporation

    发明人： Jordi Parramon ,  Rafael Carbunaru ,  Matt I. Haller

    IPC分类号： A61N1/36 ,  A61N1/05

    CPC分类号： A61N1/36171 ,  A61N1/05 ,  A61N1/0551 ,  A61N1/36 ,  A61N1/36071 ,  A61N1/36125 ,  A61N1/36175 ,  A61N1/36178 ,  A61N1/37235

    摘要： A method for configuring stimulation pulses in an implantable stimulator device having a plurality of electrodes is disclosed, which method is particularly useful in adjusting the electrodes by current steering during initialization of the device. In one aspect, a set of ideal pulses for patient therapy is determined, in which at least two of the ideal pulses are of the same polarity and are intended to be simultaneous applied to corresponding electrodes on the implantable stimulator device during an initial duration. These pulses are reconstructed into fractionalized pulses, each comprised of pulse portions. The fractionalized pulses are applied to the corresponding electrodes on the device during a final duration, but the pulse portions of the fractionalized pulses are not simultaneously applied during the final duration.

    摘要翻译： 公开了一种用于在具有多个电极的可植入刺激器装置中配置刺激脉冲的方法，该方法在装置的初始化期间通过电流转向来调节电极特别有用。 在一个方面，确定用于患者治疗的一组理想脉冲，其中至少两个理想脉冲具有相同的极性并且旨在在初始持续时间期间同时施加到可植入刺激器装置上的对应电极。 这些脉冲被重建成分数脉冲，每个脉冲包括脉冲部分。 分数脉冲在最后的持续时间内施加到器件上的对应电极，但分数脉冲的脉冲部分在最后的持续时间内不被同时施加。