Column analyzer system and improved chromatograph column for use in the
system
    61.
    发明授权
    Column analyzer system and improved chromatograph column for use in the system 失效
    柱分析仪系统和改进的色谱柱用于系统

    公开(公告)号:US5228988A

    公开(公告)日:1993-07-20

    申请号:US779186

    申请日:1991-10-22

    Abstract: An analyzer system for automatic column chromatography includes chromatographic columns which are mounted in a rack. A drop removal mechanism system shakes the rack to transfer the last drop of eluate from the tip of a chromatographic column to a receptacle below the tip before the column is repositioned over another receptacle and another fluid or operation is introduced into the column. This prevents one eluate from contaminating another. The chromatographic column may have an upper end which is sealed by a foil member. During use, the foil member is ruptured by lowering a pressure cylinder with a seal-punching head against it. The pressure cylinder, which is part of the pressure tip unit, is then withdrawn so that fluid can be introduced into the column via the ruptured foil member. The pressure tip unit is then lowered into sealing engagement with the column so that pressure can be applied via a bore in the pressure cylinder. The column may also have a tip portion which is originally sealed by a removable cap. The rack has a plate with aperture that is configured to receive the tip portion of the column and to provide a bearing surface for a decapper member which removes the cap. This decapper member is lowered through the aperture, and the bearing surface forces it toward the tip portion so that the cap can be pushed off. After the chromatographic columns have been used, they can be regenerated for re-use without removing them from the rack.

    Abstract translation: 用于自动柱层析的分析仪系统包括安装在机架中的色谱柱。 在将色谱柱重新定位在另一个容器上之前,一个液滴去除机构系统将使最后一滴洗脱液从色谱柱顶端转移到尖端下面的容器中,并将另一种流体或操作引入柱中。 这样可以防止一种洗脱液污染另一种洗脱液。 色谱柱可以具有由箔构件密封的上端。 在使用过程中,通过用冲压头将压力缸降低而使箔片破裂。 然后将作为压头单元的一部分的压力缸抽出,使得可以通过破裂的箔构件将流体引入柱中。 然后将压头单元降低成与柱的密封接合,使得可以经由压力缸中的孔施加压力。 该柱还可以具有最初由可移除盖密封的尖端部分。 齿条具有带孔的板,该板被配置为容纳柱的顶端部分,并提供用于去除盖的拆卸构件的支承表面。 该开口部件通过孔径下降,并且支承面朝向顶端部分迫使其脱离。 使用色谱柱后,可以将其再生,以便重新使用,而无需将其从机架中取出。

    Method and apparatus for immunological determinations
    65.
    发明授权
    Method and apparatus for immunological determinations 失效
    用于免疫学测定的方法和装置

    公开(公告)号:US5063024A

    公开(公告)日:1991-11-05

    申请号:US377538

    申请日:1989-07-10

    CPC classification number: G01N35/1083 G01N35/109 Y10S436/808 Y10S436/809

    Abstract: The invention concerns an immunological assay system, wherein the inner face of the cuvettes is used as the solid phase. The equipment includes a displaceable carriage (8) for the cuvette set as well as, above the carriage, a dosage head (9), to which the liquid dosimeter (11) and the measurement device (19) are attached. All the operations take place automatically.

    Abstract translation: 本发明涉及免疫测定系统,其中比色杯的内表面用作固相。 该设备包括用于比色皿组的可移动托架(8)以及托架上方的剂量头(9),液体剂量计(11)和测量装置(19)附接到该剂量头。 所有操作都会自动进行。

    Compact analyzer
    66.
    发明授权
    Compact analyzer 失效
    紧凑型分析仪

    公开(公告)号:US4798705A

    公开(公告)日:1989-01-17

    申请号:US13223

    申请日:1987-02-06

    Abstract: There is disclosed an analyzer comprising a dispensing station and detecting means for detecting either a colorimetric or a potentiometric change in a test element. A pipette support is provided to assist in the liquid dispensing, such support being movably connected to the analyzer to permit the pipette support to be moved from an inoperative position to an operative position, and back.

    Abstract translation: 公开了一种分析器,其包括分配站和用于检测测试元件中的比色或电位变化的检测装置。 提供移液管支撑以帮助液体分配,这种支撑件可移动地连接到分析器,以允许移液管支撑件从不工作位置移动到操作位置并返回。

    Automatic dispensing system
    67.
    发明授权
    Automatic dispensing system 失效
    自动点胶系统

    公开(公告)号:US4623008A

    公开(公告)日:1986-11-18

    申请号:US639478

    申请日:1984-08-10

    CPC classification number: G01N35/109 G01N35/1004 G01N35/1095 Y10T137/2499

    Abstract: A system for automatically dispensing stock solutions is disclosed, comprising a dispenser, pipette keeping and washing units and a control unit. The respective pipette keeping and washing units have different types of pipettes. First, the control unit selects the most appropriate pipette according to the type and amount of mixture of stock solutions to be prepared. The dispenser then receives the selected pipette from the corresponding pipette keeping and washing unit and is detachably fitted with the appropriate pipette to feed a predetermined amount of stock solution into a receptacle by manipulating the pipette. Having finished dispensing, the dispenser transfers the used pipette back to the corresponding pipette keeping and washing unit. On completion of the transfer, the control unit causes the pipette keeping and washing unit to wash the transferred pipette. In the meanwhile, the control unit selects another pipette and the dispenser dispenses stock solution in the receptacles by using the newly selected pipette. Thus, the processing of dispensing stock solutions to the receptacles can be efficiently effected by saving the time loss which would be caused by interruptions for cleaning the pipette.Further a secondary feature of the invention includes an apparatus for automatically preparing stock solutions thereby saving the time and labor which would be required in manually preparing stock solutions.

    Abstract translation: 公开了一种用于自动分配原料溶液的系统,包括分配器,移液管保持和洗涤单元以及控制单元。 相应的移液器保持和洗涤单元具有不同类型的移液管。 首先,控制单元根据要准备的储备溶液的混合物的类型和量选择最合适的移液管。 然后,分配器从相应的移液管保持和洗涤单元接收所选择的移液管,并且可拆卸地装配有适当的移液管,以通过操纵移液管将预定量的储液溶液供给到容器中。 完成分配后,分配器将使用的移液器转移回相应的移液器保持和清洗单元。 转移完毕后,控制单元使移液管保持和清洗单元清洗转移的移液管。 同时,控制单元选择另一移液管,并且分配器通过使用新选择的移液管来分配容器中的储液。 因此,通过节省由于清洗移液管的中断而引起的时间损失,可以有效地实现将储液分配到容器的处理。 此外,本发明的第二个特征包括一种用于自动制备原料溶液的装置,从而节省了手动制备原料溶液所需的时间和劳动。

    Delivering apparatus
    68.
    发明授权
    Delivering apparatus 失效
    交付工具

    公开(公告)号:US4311667A

    公开(公告)日:1982-01-19

    申请号:US140567

    申请日:1980-04-15

    Applicant: Nagahiro Gocho

    Inventor: Nagahiro Gocho

    CPC classification number: G01N35/109 B01J4/02 G01N2035/1093 G01N35/1004

    Abstract: An apparatus comprising a delivering device including a probe and operative to suck at least one kind of liquids such as a plurality of reagents, samples or the like from respective vessels into the probe and deliver the liquid thus sucked from the probe into a reaction vessel. In such kind of delivering apparatus, provision is made of the improvement in which the probe is movable along a given moving path, the vessels containing the liquids to be delivered being provided with suction openings arranged at a plurality of fixed positions along the moving path of the probe, and in which the reaction vessel is movable along a path adjacent to and crossed with the moving path of the probe, and in which provision is made of means for locating the probe at any sucking position or at a delivering position with respect to the reaction vessel where the moving path of the probe is adjacent to or crossed with the moving path of the reaction vessel.

    Abstract translation: 一种装置,包括:包括探针的输送装置,用于将来自相应容器的至少一种液体,例如多个试剂,样品等吸入探针中,并将从探针吸入的液体输送到反应容器中。 在这种输送装置中,提供探头可沿着给定的移动路径移动的改进,容纳待输送液体的容器设置有沿着沿着移动路径的移动路径的多个固定位置 探针,其中反应容器可以沿着与探头的移动路径相邻并与其交叉的路径移动,并且其中设置有用于将探针定位在任何吸取位置或相对于 探针的移动路径与反应容器的移动路径相邻或与之交叉的反应容器。

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