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197 条记录 (耗时 0.033 秒)

    Inhibitor of kainic acid neurotoxicity and pyridothiazine derivative
    73.
    发明授权
    Inhibitor of kainic acid neurotoxicity and pyridothiazine derivative 失效
    红藻氨酸神经毒性抑制剂和吡啶并噻嗪衍生物

    公开(公告)号：US6133258A

    公开(公告)日：2000-10-17

    申请号：US68534

    申请日：1998-05-13

    申请人： Jun-ichi Shishikura ,  Hiroshi Inami ,  Tomoyuki Yasunaga ,  Masaaki Hirano ,  Shuichi Sakamoto ,  Kazushige Ohno ,  Masamichi Okada ,  Shin-ichi Tsukamoto

    发明人： Jun-ichi Shishikura ,  Hiroshi Inami ,  Tomoyuki Yasunaga ,  Masaaki Hirano ,  Shuichi Sakamoto ,  Kazushige Ohno ,  Masamichi Okada ,  Shin-ichi Tsukamoto

    IPC分类号： A61K31/5415 ,  A61K31/542 ,  C07D513/04

    CPC分类号： A61K31/5415

    摘要： Neuroprotective agents based on inhibition of kainic acid neurotoxicity and compounds useful as neuroprotective agents based on inhibition of kainic acid neurotoxicity. An inhibitors of kainic acid neurotoxicity, comprising as an active ingredient a pyridothiazine derivative represented by the following general formula (I) or a pharmaceutically acceptable salt thereof, and a pyridothiazine derivative represented by the following general formula (I) or a pharmaceutically acceptable salt thereof: ##STR1## wherein symbols in the formula have the following respective meanings: the ring A: a pyridine ring; ##STR2## R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 may be the same or different and each represent a hydrogen atom or a lower alkyl, cycloalkyl, alkenyl, aryl, carboxyl or lower alkoxycarbonyl group which may have substituent(s), or are not present, with the proviso that R.sup.2 and R.sup.3 may together form a nitrogen-containing heterocyclic group which may have nitrogen atoms as another hetero atom, may be fused with a benzene ring and may have a lower alkyl group as a substituent.

    摘要翻译： PCT No.PCT / JP96 / 03339 Sec。 371日期1998年5月13日 102（e）日期1998年5月13日PCT 1996年11月14日PCT PCT。 出版物WO97 / 17970 日期1997年5月22日基于抑制红藻氨酸神经毒性的神经保护剂和基于抑制红藻氨酸神经毒性作用的神经保护剂的化合物。 作为活性成分的红藻氨酸神经毒性抑制剂，含有下述通式（I）所示的吡哆噻嗪衍生物或其药学上可接受的盐，以及下述通式（I）表示的吡哒嗪衍生物或其药学上可接受的盐 其中式中的符号具有以下各自的含义：环A：吡啶环; R 1，R 2，R 3，R 4和R 5可以相同或不同，各自表示氢原子或可以具有取代基或不存在的低级烷基，环烷基，烯基，芳基，羧基或低级烷氧基羰基， 条件是R2和R3可以一起形成可以具有氮原子作为另一个杂原子的含氮杂环基，可以与苯环稠合并且可以具有低级烷基作为取代基。

    Method for manufacturing honeycomb structure
    75.
    发明授权
    Method for manufacturing honeycomb structure 有权
    蜂窝结构体的制造方法

    公开(公告)号：US08110139B2

    公开(公告)日：2012-02-07

    申请号：US12044858

    申请日：2008-03-07

    申请人： Kazushige Ohno ,  Masafumi Kunieda ,  Masatoshi Okuda

    发明人： Kazushige Ohno ,  Masafumi Kunieda ,  Masatoshi Okuda

    IPC分类号： B28B1/00 ,  B28B3/00 ,  B28B5/00 ,  C04B33/32 ,  C04B33/36 ,  C04B35/64 ,  B29C47/00 ,  B29C47/12

    CPC分类号： B01D46/0001 ,  B01D46/2418 ,  B01D46/2459

    摘要： A honeycomb structure is manufactured by molding a pillar-shaped honeycomb molded body having a large number of cells disposed in parallel with one another in a longitudinal direction with a cell wall therebetween by extrusion-molding a raw material composition including a ceramic powder and a binder, and carrying out a firing treatment on the honeycomb molded body to manufacture a honeycomb fired body. A plurality of the honeycomb fired bodies are provided, and both end faces of each of the plurality of the honeycomb fired bodies are hold with a holding member after positioning the plurality of the honeycomb fired bodies on a predetermined position. An adhesive paste is injected into a gap between the plurality of honeycomb fired bodies held on the predetermined position. The adhesive paste is dried and solidified to form an adhesive layer.

    摘要翻译： 通过将包含陶瓷粉末和粘合剂的原料组合物挤出成型，将具有多个细胞的柱状蜂窝成型体在长度方向成型，通过将细胞壁挤压成型，制造蜂窝结构体 对蜂窝成形体进行烧成处理，制造蜂窝烧制体。 设置多个蜂窝烧制体，并且在将多个蜂窝烧制体定位在预定位置之后，多个蜂窝烧制体的两个端面保持有保持构件。 将粘合剂浆料注入到保持在预定位置上的多个蜂窝烧制体之间的间隙中。 将粘合剂糊剂干燥并固化以形成粘合剂层。

    Honeycomb structure
    79.
    发明授权
    Honeycomb structure 有权
    蜂窝结构

    公开(公告)号：US07879429B2

    公开(公告)日：2011-02-01

    申请号：US11321882

    申请日：2005-12-30

    申请人： Kazushige Ohno ,  Masafumi Kunieda ,  Kazutake Ogyu

    发明人： Kazushige Ohno ,  Masafumi Kunieda ,  Kazutake Ogyu

    IPC分类号： B32B3/12

    CPC分类号： F01N3/0222 ,  B01J23/02 ,  B01J23/40 ,  B01J35/04 ,  B01J37/0215 ,  C04B35/80 ,  C04B38/0016 ,  C04B2111/00129 ,  C04B2111/00793 ,  C04B2111/0081 ,  C04B2111/2084 ,  Y02T10/20 ,  Y10T428/24149

    摘要： A honeycomb structure having multiple honeycomb units united through a seal material layer, wherein each honeycomb unit has multiple through holes arranged side by side in a longitudinal direction and separated from each other by the wall surfaces of the through holes, is disclosed. The honeycomb units include at least: ceramic particles; and at least one of inorganic fibers and whiskers. At least one of the honeycomb units has a cross section perpendicular to a longitudinal direction thereof, the cross section having an area greater than or equal to about 5 cm2 and less than or equal to about 50 cm2. For each of the honeycomb units, the ratio of the thermal conductivity of the honeycomb unit to the thermal conductivity of the seal material layer falls within the range of about 0.2 to about 5.

    摘要翻译： 公开了一种蜂窝结构体，其具有通过密封材料层结合的多个蜂窝单元，其中，每个蜂窝单元具有沿纵向并排布置并且通过通孔的壁表面彼此分离的多个通孔。 蜂窝单元至少包括：陶瓷颗粒; 和无机纤维​​和晶须中的至少一种。 蜂窝单元中的至少一个具有垂直于其纵向方向的横截面，该横截面具有大于或等于约5cm 2且小于或等于约50cm 2的面积。 对于每个蜂窝单元，蜂窝单元的热导率与密封材料层的导热率之比落在约0.2至约5的范围内。

    Honeycomb structure
    80.
    发明授权
    Honeycomb structure 有权
    蜂窝结构

    公开(公告)号：US07879427B2

    公开(公告)日：2011-02-01

    申请号：US11320974

    申请日：2005-12-30

    申请人： Kazushige Ohno ,  Masafumi Kunieda ,  Kazutake Ogyu

    发明人： Kazushige Ohno ,  Masafumi Kunieda ,  Kazutake Ogyu

    IPC分类号： B32B3/12

    CPC分类号： F01N3/2828 ,  B01D39/2086 ,  B01D39/2089 ,  F01N2450/28 ,  Y10T428/24149

    摘要： A honeycomb structure having multiple honeycomb units united through a seal material layer, wherein each honeycomb unit has multiple through holes arranged side by side in a longitudinal direction and separated from each other by the wall surfaces of the through holes, is disclosed. The honeycomb units include at least: ceramic particles; and at least one of inorganic fibers and whiskers. At least one of the honeycomb units has a cross section perpendicular to a longitudinal direction thereof, the cross section having an area greater than or equal to about 5 cm2 and less than or equal to about 50 cm2. Each corner of each honeycomb unit has a shape of one of a substantially rounded surface and a substantially chamfered surface.

    摘要翻译： 公开了一种蜂窝结构体，其具有通过密封材料层结合的多个蜂窝单元，其中，每个蜂窝单元具有沿纵向并排布置并且通过通孔的壁表面彼此分离的多个通孔。 蜂窝单元至少包括：陶瓷颗粒; 和无机纤维​​和晶须中的至少一种。 蜂窝单元中的至少一个具有垂直于其纵向方向的横截面，该横截面具有大于或等于约5cm 2且小于或等于约50cm 2的面积。 每个蜂窝单元的每个角都具有基本圆形的表面和基本上倒角的表面之一的形状。