公开(公告)号：US5556138A

公开(公告)日：1996-09-17

申请号：US411566

申请日：1995-03-28

申请人： Hiroshi Nakajima ,  Toshio Tsuboko

发明人： Hiroshi Nakajima ,  Toshio Tsuboko

IPC分类号： F16L23/024 ,  B60H1/00 ,  B60H1/32 ,  F16L23/026 ,  F16L23/028 ,  F16L39/00 ,  F16L39/04 ,  F25B41/00 ,  F16L35/00 ,  F16L3/22 ,  F16L23/02

CPC分类号： B60H1/00571 ,  F16L39/00

摘要： Connection of two dividing flanges by joining of protrusion and depression, protrusion and depression, and protrusion and notch, in addition to tightening and joining by means of self-tapping screw to create the connecting flange. At this time, the hexagonal nut is located beforehand in the insertion hole created on dividing flange, and the hexagonal bolt passed from the connecting flange on the side for connection is screwed to the hexagonal nut.

摘要翻译： 除了通过自攻螺钉拧紧和接合以形成连接法兰之外，通过连接突起和凹陷，突出和凹陷以及突出和凹口来连接两个分隔凸缘。 此时，六角螺母预先位于分隔法兰上形成的插入孔中，并且从连接侧的连接法兰通过的六角螺栓被拧入六角螺母。

公开(公告)号：US5247047A

公开(公告)日：1993-09-21

申请号：US817637

申请日：1992-01-07

申请人： Tadayuki Hosogane ,  Hiroshi Nakajima

发明人： Tadayuki Hosogane ,  Hiroshi Nakajima

IPC分类号： C07D207/44 ,  C07D207/452 ,  C08G18/34 ,  C08G18/67 ,  C08G69/00 ,  C08L77/00

CPC分类号： C07D207/452 ,  C08G18/341 ,  C08G18/671 ,  C08G18/6715 ,  C08G18/6735 ,  C08G18/6755 ,  C08G69/00 ,  C08L77/00

摘要： Aromatic polyamide oligomers containing polymerizable unsaturated groups are prepared by heating and reacting together an aromatic diisocyanate, an aromatic dicarboxylic acid and an unsaturated compound capable of reacting with the aromatic diisocyanate. The aromatic polyamide oligomers thus obtained have excellent molding processability and are useful as raw materials for thermosetting polyamides with enhanced mechanical strength and chemical stability at higher temperatures. The compositions comprising the aromatic polyamide oligomers and maleimide derivatives, further produce cured molded bodies with excellent heat resistance.

公开(公告)号：US5144279A

公开(公告)日：1992-09-01

申请号：US705652

申请日：1991-05-24

申请人： Yasuhito Yajima ,  Hiroshi Nakajima

发明人： Yasuhito Yajima ,  Hiroshi Nakajima

IPC分类号： H01C7/02

CPC分类号： H01C7/021

摘要： A resistor element for determining a parameter, which includes a ceramic support having a bearing surface, an electrically resistive metallic layer formed on the bearing surface of the ceramic support, and a glass coating covering the metallic layer. The metallic layer has a plurality of pores which extend from an outer surface of the metallic layer to the bearing surface of the ceramic support, each pore having an area which is not smaller than that of a circle having a diameter of 1 .mu.m. An average spacing between adjacent ones of the pores is not larger than 5 .mu.m.

摘要翻译： 一种用于确定参数的电阻元件，其包括具有支承表面的陶瓷支撑体，形成在所述陶瓷支撑体的支承表面上的电阻金属层和覆盖所述金属层的玻璃涂层。 金属层具有从金属层的外表面延伸到陶瓷载体的支承面的多个孔，每个孔的面积不小于直径为1μm的圆的面积。 相邻的孔之间的平均间隔不大于5μm。

公开(公告)号：US5001055A

公开(公告)日：1991-03-19

申请号：US862731

申请日：1986-05-13

申请人： Kazutomo Imahori ,  Isao Tomioka ,  Hiroshi Nakajima ,  Senji Kitabatake

发明人： Kazutomo Imahori ,  Isao Tomioka ,  Hiroshi Nakajima ,  Senji Kitabatake

IPC分类号： C07H19/20 ,  C12P1/00 ,  C12P13/00 ,  C12P13/04 ,  C12P13/14 ,  C12P19/02 ,  C12P19/32

CPC分类号： C12P13/001 ,  C07H19/20 ,  C12P1/00 ,  C12P13/00 ,  C12P13/04 ,  C12P13/06 ,  C12P13/14 ,  C12P13/20 ,  C12P19/02 ,  C12P19/32 ,  Y10S435/813

摘要： A process for producing a physiologically active substance by a combined enzymatic method is disclosed. In the combined enzymatic method, a reactant solution containing a precursor or precursors for the physiologically active substance, AXP, and a divalent metal ion is supplied at one end of a reactor incorporating either the combined enzymatic reaction system (a) or (b), wherein (a) is a reaction system including an enzyme for converting AMP to ADP, an enzyme for converting ADP to ATP, and an enzyme which catalyzes the synthesis of the physiologically active substance as it converts ATP to AMP; and (b) is a reaction system including an enzyme for converting ADP to ATP and an enzyme which catalyzes the synthesis of the physiologically active substance as it converts ATP to ADP, wherein the concentration of the divalent metal ion supplied into the reactor is held at a level no higher than 30 mM while the concentration of the AXP is held below that of that of the precursor or precursors for the physilogically active substance, and the physiologically active substance produced is withdrawn from the other end of the reactor.

摘要翻译： 公开了通过组合的酶法生产生理活性物质的方法。 在组合的酶法中，在包含组合的酶反应体系（a）或（b）的反应器的一端提供含有生理活性物质前体或前体的反应物溶液AXP和二价金属离子， 其中（a）是包含用于将AMP转化成ADP的酶的反应体系，用于将ADP转化为ATP的酶，以及当ATP转化成AMP时催化生理活性物质合成的酶; 和（b）是包含用于将ADP转化为ATP的酶的反应体系，以及当ATP向ADP转化时催化生理活性物质的合成的酶，其中供给到反应器中的二价金属离子的浓度保持在 水平不高于30mM，而AXP的浓度低于物理活性物质的前体或前体的浓度，生成的生理活性物质从反应器的另一端排出。

公开(公告)号：US4800435A

公开(公告)日：1989-01-24

申请号：US932671

申请日：1986-11-20

申请人： Sadayuki Ikeda ,  Hidehiko Inoue ,  Kiyotake Nagai ,  Hiroshi Nakajima ,  Yasuichi Ushiyama

发明人： Sadayuki Ikeda ,  Hidehiko Inoue ,  Kiyotake Nagai ,  Hiroshi Nakajima ,  Yasuichi Ushiyama

IPC分类号： H04N3/15 ,  H04N3/14

CPC分类号： H04N3/1556 ,  H04N3/1531

摘要： An image sensing device for a TV camera and method of driving the same is disclosed whereby the effective charge accumulation time in each light-sensing row in the imaging area can be reduced thereby eliminating fuzzy images produced when fast moving objects are picked up. The driving circuit of the imaging device gives the sensor a shutter function of less than 1/60 second and up to 1/2000 second exposure time without changing the structure of the sensor. There is provided a method in which charges accumulated in each row of the light-sensing elements are taken out and discarded at an optional time during an active video period, leaving an effective charge accumulation period of less than 1/60 second.

摘要翻译： 公开了一种用于TV摄像机的图像感测装置及其驱动方法，由此可以减少成像区域中每个感光行中的有效电荷累积时间，从而消除了当快速移动的物体被拾取时产生的模糊图像。 成像装置的驱动电路给传感器提供小于1/60秒和高达1/2000秒曝光时间的快门功能，而不改变传感器的结构。 提供了一种方法，其中在活动视频周期期间的任选时间取出在每一行感光元件中累积的电荷并丢弃，留下小于1/60秒的有效电荷累积周期。

公开(公告)号：US4668631A

公开(公告)日：1987-05-26

申请号：US777674

申请日：1985-09-19

申请人： Akira Obayashi ,  Nobutsugu Hiraoka ,  Keiko Kita ,  Hiroshi Nakajima

发明人： Akira Obayashi ,  Nobutsugu Hiraoka ,  Keiko Kita ,  Hiroshi Nakajima

IPC分类号： C12N15/09 ,  C12N9/16 ,  C12N9/22 ,  C12R1/01

CPC分类号： C12N9/22 ,  Y10S435/822

摘要： A restriction endonuclease having the ability to recognize the same base sequence and cleavage sites as SacII and SstII can be produced from Gluconobacter and isolated in pure form because no other restriction enzyme is formed.

摘要翻译： 具有识别与SacII和SstII相同的碱基序列和切割位点的能力的限制性内切核酸酶可由葡糖杆菌产生并以纯形式分离，因为不形成其它限制酶。

公开(公告)号：US4584272A

公开(公告)日：1986-04-22

申请号：US309346

申请日：1981-10-07

申请人： Kazutomo Imahori ,  Hiroshi Nakajima ,  Kazuhiko Nagata

发明人： Kazutomo Imahori ,  Hiroshi Nakajima ,  Kazuhiko Nagata

IPC分类号： C12N9/12 ,  C12N11/00 ,  C12P1/00 ,  C12P19/32 ,  C12R1/07

CPC分类号： C12P1/00 ,  C12N11/00 ,  C12N9/12 ,  Y10S435/832

摘要： A heat-resistant adenylate kinase is described whose activity after an incubation in a buffer solution at about 50.degree. C. for about 15 minutes is at least about 80% of the original activity prior to the incubation. This adenylate kinase can be obtained by cultivating a bacterium belonging to the genus Bacillus and collecting adenylate kinase from the resulting culture broth. This heat-resistant enzyme is very stable against heat and, therefore, after isolation, it can be stored for a long period of time compared with the conventional adenylate kinase.

摘要翻译： 描述了耐热腺苷酸激酶，其在约50℃下在缓冲溶液中孵育约15分钟后的活性是孵育前至少约80％的原始活性。 该腺苷酸激酶可以通过培养属于芽孢杆菌属的细菌并从得到的培养肉汤中收集腺苷酸激酶来获得。 该耐热酶对于热是非常稳定的，因此在分离后，与常规腺苷酸激酶相比可以长时间储存​​。

公开(公告)号：US4554253A

公开(公告)日：1985-11-19

申请号：US461309

申请日：1983-01-26

申请人： Kazutomo Imahori ,  Tatsuo Iwasaki ,  Hiroshi Nakajima ,  Hitoshi Kondo ,  Isao Tomioka ,  Masaru Kashima ,  Toshihiko Tsukamoto

发明人： Kazutomo Imahori ,  Tatsuo Iwasaki ,  Hiroshi Nakajima ,  Hitoshi Kondo ,  Isao Tomioka ,  Masaru Kashima ,  Toshihiko Tsukamoto

IPC分类号： C12M1/40 ,  C12P1/00 ,  C12P13/20 ,  C12P19/32 ,  C12P21/02

CPC分类号： C12P13/20 ,  C12M21/14 ,  C12M21/18 ,  C12M25/18 ,  C12M47/12 ,  C12P1/00 ,  C12P19/32 ,  C12P21/02

摘要： An apparatus for converting into ATP which comprises an enzyme reactor, a source of AMP supply, a source of phosphoric acid donator supply, variable fluid sending apparatus, an automatic sampling apparatus and an analyzing apparatus for the reacting solution, an arithmetic control apparatus, and a recovery apparatus. According to this apparatus, conversion from AMP or ADP into ATP can be effectively carried out and ATP conversion can be kept at substantial 100% over a long period of time. The device makes it possible for ATP to be used more and more in future as an energy source for bioreactors and as medicines because the ATP will be more readily available and less expensive.

摘要翻译： 一种用于转化成ATP的装置，包括酶反应器，AMP供应源，磷酸供体源，可变流体送出装置，自动取样装置和用于反应溶液的分析装置，运算控制装置和 恢复装置。 根据该装置，可以有效地进行从AMP或ADP向ATP的转化，并且可以长时间将ATP转化率保持在100％左右。 该装置可以使ATP越来越多地被用作生物反应器和药物的能源，因为ATP将更容易获得并且更便宜。

公开(公告)号：US4331762A

公开(公告)日：1982-05-25

申请号：US209097

申请日：1980-11-21

申请人： Hiroshi Nakajima ,  Kazuhiko Nagata ,  Masao Kageyama ,  Toyohiko Suga ,  Tadao Suzuki ,  Kenzo Motosugi

发明人： Hiroshi Nakajima ,  Kazuhiko Nagata ,  Masao Kageyama ,  Toyohiko Suga ,  Tadao Suzuki ,  Kenzo Motosugi

IPC分类号： C12N9/00 ,  C12N9/04 ,  C12N9/12 ,  C12N1/20

CPC分类号： C12N9/0006 ,  C12N9/00 ,  C12N9/1258 ,  C12R1/07 ,  Y10S435/832

摘要： Strain UK 788 (FERM-P No. 5141) that belongs to Bacillus stearothermophilus, the cell of which is longer than about 10 microns and which permits easier release of intracellular components than a type culture Bacillus stearothermophilus, IAM 11001 is disclosed. Also, a process for producing a useful enzyme selected from the group consisting of a heat-resistant polynucleotide phosphorylase, heat-resistant maleate dehydrogenase, heat-resistant glucokinase, heat-resistant glucose-6-phosphate dehydrogenase and heat-resistant pyruvate kinase by culturing such UK 788 and recovering the desired enzyme from the culture is disclosed. Since the cell of the strain UK 788 is easy to settle and its membrane is also easy to break, the useful enzymes mentioned above can be efficiently produced on an industrial scale.

摘要翻译： 属于嗜热脂肪芽孢杆菌的菌株UK788（FERM-P编号5141），其细胞长于约10微米，并且允许比类型培养的嗜热脂肪芽孢杆菌IAM 11001更容易释放细胞内组分。 此外，通过培养生产选自耐热多核苷酸磷酸化酶，耐热马来酸脱氢酶，耐热葡萄糖激酶，耐热葡萄糖-6-磷酸脱氢酶和耐热丙酮酸激酶的有用酶的方法 公开了这样的英国788并从培养物中回收所需的酶。 由于菌株UK 788的细胞容易沉降并且其膜也易于破裂，所以上述有用的酶可以在工业规模上有效地生产。

公开(公告)号：US4068070A

公开(公告)日：1978-01-10

申请号：US648493

申请日：1976-01-12

申请人： Katsumi Sakai ,  Yukio Onogawa ,  Yoshitaka Inamoto ,  Hiroshi Nakajima ,  Yasuo Fujimoto ,  Kuniichiro Ohno ,  Masashi Yoshida ,  Shigehito Araki

发明人： Katsumi Sakai ,  Yukio Onogawa ,  Yoshitaka Inamoto ,  Hiroshi Nakajima ,  Yasuo Fujimoto ,  Kuniichiro Ohno ,  Masashi Yoshida ,  Shigehito Araki

IPC分类号： C07D295/145 ,  C07D295/205 ,  C07D295/08 ,  C07D295/04

CPC分类号： C07D295/205 ,  C07D295/145

摘要： .alpha.-Cyanoamine compounds represented by the following formula or an acid addition salt thereof ##STR1## WHEREIN R.sub.1 is a halogen atom or lower alkoxy group, R.sub.2 and R.sub.3 are a hydrogen atom or lower alkoxy group, R.sub.4 is a hydrogen atom or lower alkyl group, R.sub. 5 is a hydrogen atom, --COOR.sub.6 (R.sub.6 is lower alkyl group), ##STR2## (R.sub.7 is lower alkoxy group, m is a numeral 0-3), --R.sub.8 --COOR.sub.9 (R.sub.8 is lower alkylene group, R.sub.9 is lower alkyl group), ##STR3## (R.sub.10 and R.sub.11 are a hydrogen atom or lower alkyl group, or R.sub.10 and R.sub.11 jointly form alkylene group), or ##STR4## (R.sub.1 to R.sub.4 are the same as defined above) and n is a numeral 2 or 3; but it is excluded when R.sub.5 is hydrogen atom or --COOR.sub.6 (R.sub.6 is the same as defined above) and n is a numeral 2, which are produced by reacting aromatic carbonyl compounds with piperazine or homopiperazine compounds in the presence of hydrogen cyanide or salts thereof, or which are alternatively produced by reaction N-(.alpha.-cyanobenzyl)-piperazines of N-(.alpha.-cyanobenzyl)homopiperazines or acid addition salts thereof with halogenated compounds.

摘要翻译： 由下式表示的α-氰胺化合物或其酸加成盐其中R1是卤素原子或低级烷氧基，R2和R3是氢原子或低级烷氧基，R4是氢原子或低级烷基 ，R 5为氢原子，-COOR 6（R6为低级烷基），R7为低级烷氧基，m为0-3，-R8-COOR9（R8为低级亚烷基，R9为 （R 10和R 11为氢原子或低级烷基，或R 10和R 11共同形成亚烷基），或者（R 1〜R 4与上述相同），n为 数字2或3; 但是当R5是氢原子或-COOR6（R6与上述定义相同）时，不包括它们，n是数字2，它们是在芳香族羰基化合物与哌嗪或高哌嗪化合物在氰化氢或其盐存在下反应制备的 ，或者可选地由N-（α-氰基苄基）高哌嗪的N-（α-氰基苄基） - 哌嗪或其与卤化化合物的酸加成盐反应生成。