Abstract:
A method of synthesizing 2S*, 3R*-6E-(2-hydroxyethylidene)-2-methyl-2-(4,8-dimethyl-5-oxo-7-nonenyl)-oxepan-3-ol, one of the active ingredients in the zoapatle plant, is described. The natural product is useful as a utero-evacuant agent.
Abstract:
A novel method for preparing pentachloronitrobenzene directly from the corresponding pentachlorobenzonitrile compound is disclosed. Pentachlorobenzonitrile is heated in the presence of an excess of sulfuric acid and a nitrating agent, e.g., nitric acid at elevated temperatures of from about 100.degree.C to about 160.degree.C for a time sufficient to convert the pentachlorobenzonitrile to a pentachloronitrobenzene.In one embodiment the pentachlorobenzonitrile compound is first heated in the presence of an excess of concentrated sulfuric acid at temperatures in excess of 180.degree.C to activate the pentachlorobenzonitrile and the activated material is then heated at lower temperatures of about 100.degree. to 120.degree.C in the presence of a nitrating agent to convert the activated pentachlorobenzonitrile to the corresponding pentachloronitrobenzene.
Abstract:
Alpha -nitro-cinnamic acid derivatives which are useful in preparing phenylalanines, and a process for obtaining the derivatives by treating the corresponding cinnamic acid esters with nitric oxide or nitrogen dioxide.
Abstract:
The disclosure is directed to: (a) phosphacycle ligands; (b) catalyst compositions comprising phosphacycle ligands; and (c) methods of using such phosphacycle ligands and catalyst compositions in bond forming reactions.
Abstract:
Disclosed herein is a method for synthesizing terpenoid compounds, as well as compositions comprising terpenoids and methods for their use. In one aspect the process is represented by the scheme wherein G is X is and R1, R2 and R3 independently are selected from H, acyl, lower alkyl and aralkyl; and Y is —O—, —S— or —NH—, and R4 is selected from H, acyl, lower alkyl and aralkyl.
Abstract:
The disclosure is directed to: (a) phosphacycle ligands; (b) methods of using such phosphacycle ligands in bond forming reactions; and (c) methods of preparing phosphacycle ligands.