公开(公告)号：US20240335657A1

公开(公告)日：2024-10-10

申请号：US18731925

申请日：2024-06-03

申请人： Washington University ,  Northwestern University

发明人： Wilson Z. Ray ,  Matthew R. MacEwan ,  Zohny S. Zohny ,  John A. Rogers

IPC分类号： A61N1/20 ,  A61N1/04 ,  A61N1/05 ,  A61N1/372 ,  A61N1/375

CPC分类号： A61N1/205 ,  A61N1/0456 ,  A61N1/0504 ,  A61N1/37217 ,  A61N1/375 ,  A61N1/20

摘要： A system for stimulating tissue generally comprises a resorbable implant. The resorbable implant includes a substrate, at least one contact, and a transceiver, wherein the substrate, the at least one contact, and the transceiver are resorbable. The system also includes a controller configured to communicate with the transceiver of the resorbable implant and a power supply connected to the controller. The controller delivers power to the resorbable implant from the power supply. The resorbable implant delivers electrical stimulation to tissue when the resorbable implant receives power.

公开(公告)号：US20240335506A1

公开(公告)日：2024-10-10

申请号：US18294048

申请日：2022-08-04

申请人： The United States of America,as represented by the Secretary,Department of Health and Human Services

发明人： John A. Chiorini ,  Matthew P. Hoffman

IPC分类号： A61K38/17 ,  A61K48/00 ,  A61N5/10 ,  A61P1/00 ,  C12N15/86

CPC分类号： A61K38/1709 ,  A61K48/0033 ,  A61K48/0075 ,  A61P1/00 ,  C12N15/86 ,  A61N5/10 ,  C12N2750/14143

摘要： Administration of aquaporin-1 (AQP1) complementary deoxyribonucleic acid (cDNA) to a salivary gland prior to treatment with ionizing radiation (IR) prevents the subsequent IR-induced loss in function. The administration of AQPI (e.g., human AQP1: hAQP1) prior to IR treatment (e.g., in patients with head and neck cancer) can reduce or prevent IR-induced salivary hypofunction, resulting in an elevated salivary output.

公开(公告)号：US20240335157A1

公开(公告)日：2024-10-10

申请号：US18743538

申请日：2024-06-14

申请人： Advanced Bionics AG

发明人： Anil K. Patnala ,  Kanthaiah Koka

IPC分类号： A61B5/38 ,  A61B5/12 ,  A61B5/24 ,  A61B5/291 ,  A61N1/05 ,  A61N1/36 ,  H04R25/00

CPC分类号： A61B5/38 ,  A61B5/125 ,  A61B5/24 ,  A61B5/291 ,  A61N1/0541 ,  A61N1/36039 ,  H04R25/505 ,  H04R25/70

摘要： An illustrative electroacoustic hearing system includes a loudspeaker and a processor configured to: direct the loudspeaker to present a sound to a recipient by way of a length of tubing extending from the loudspeaker to an ear tip disposed at an ear canal of the recipient, the directing configured to cause the sound to have a target sound pressure level at the ear canal; obtain a detected sound pressure level of the sound as the sound is presented at the ear canal, the detected sound pressure level obtained from a probe microphone disposed within the ear tip; identify a discrepancy between the detected and target sound pressure levels of the sound as the sound is presented at the ear canal; and direct, based on the identified discrepancy, a remedial action to be performed to compensate for the discrepancy.

公开(公告)号：US20240335152A1

公开(公告)日：2024-10-10

申请号：US18744833

申请日：2024-06-17

申请人： Conmed Corporation

发明人： Jessica Snyder

IPC分类号： A61B5/33 ,  A61B5/263 ,  A61B5/265 ,  A61N1/04

CPC分类号： A61B5/33 ,  A61B5/263 ,  A61B5/265 ,  A61N1/046 ,  A61N1/0492

摘要： An electrode pad with a defibrillation circuit and a separate ECG tracing circuit. The electrode pad includes a foam base layer, first and second conductive layers, and a hydrogel layer. The foam base layer has a first side and the first conductive layer is centrally located on the base layer. The first conductive layer has a first circuit configured to provide a defibrillation current. The second conductive layer extends at least partially around the first conductive layer on the first side of the base layer. The second conductive layer has a separate second circuit configured to receive an electrical signal. The hydrogel layer covers the first and second conductive layers on the first side of the base layer. The electrode pad additionally includes an electrical connector attached to the first and second conductive layers. The electrical connector is configured for providing a voltage to the first and second conductive layers.

公开(公告)号：US20240335108A1

公开(公告)日：2024-10-10

申请号：US18738229

申请日：2024-06-10

申请人： Avedro, Inc.

发明人： Desmond Christopher Adler ,  Jun A. Zhang ,  Mikhail Z. Smirnov ,  Marc D. Friedman ,  David Usher ,  Grace Elizabeth Lytle ,  David C. Iannetta

IPC分类号： A61B3/107 ,  A61B3/10 ,  A61B3/14 ,  A61B5/00 ,  A61F9/007 ,  A61F9/008 ,  A61N5/06

CPC分类号： A61B3/107 ,  A61B3/10 ,  A61B3/14 ,  A61B5/0036 ,  A61F9/0079 ,  A61N5/062 ,  A61B5/0071 ,  A61B5/4848 ,  A61F2009/00872 ,  A61N2005/0661

摘要： In a corneal measurement system, an optical element focuses an excitation light to an area of corneal tissue at a selected depth. In response, a fluorescing agent applied to the cornea generates a fluorescence emission. An aperture of a pinhole structure selectively transmits the fluorescence emission from the area of corneal tissue at the selected depth. A detector captures the selected fluorescence emission transmitted by the aperture and communicates information relating to a measurement of the selected fluorescence emission captured by the detector. A controller receives the information from the detector and determines a measurement of the fluorescing agent in the area of corneal tissue at the selected depth. The system may include a scan mechanism that causes the optical element to scan the cornea at a plurality of depths, and the controller may determine a measurement of the fluorescing agent in the cornea as a function of depth.

公开(公告)号：US12109436B2

公开(公告)日：2024-10-08

申请号：US17883473

申请日：2022-08-08

申请人： OUR UNITED CORPORATION

发明人： Jinsheng Li ,  Hao Yan ,  Tianchang Gou

IPC分类号： A61N5/10

CPC分类号： A61N5/1069 ,  A61N2005/1059 ,  A61N2005/1076

摘要： A control method for positioning is provided, which is applicable to a radiotherapy system. The method includes: acquiring a plurality of first body surface coordinates of a target site in a three-dimensional body surface image of a treatment object on a treatment couch; acquiring a plurality of second body surface coordinates under an isocentric coordinate system by transforming the first body surface coordinates using a target transformation matrix corresponding to the first placement position; determining, based on the plurality of second body surface coordinates and a contour image of the target site in the treatment plan, a placement offset of the target site, so as to control the treatment couch to move until the placement offset of the target site upon the movement meets a target offset requirement.

公开(公告)号：US12109433B2

公开(公告)日：2024-10-08

申请号：US18046035

申请日：2022-10-12

申请人： Elekta, Inc.

发明人： Louis Arunus Genet ,  Stuart Julian Swerdloff

IPC分类号： A61N5/10

CPC分类号： A61N5/1043 ,  A61N5/1039 ,  A61N5/1078 ,  A61N2005/1087 ,  A61N2005/1095

摘要： Systems and techniques may be used for radiotherapy. An example system may include a fixation device arranged to receive and immobilize a patient. The example system may include a first filter arranged to extend along a first portion (e.g., a spine or cranium) of the patient, the first filter attached to the fixation device at a first location, the first filter including a plurality of beam attenuating elements. The example system may include a fixed beam proton delivery system arranged to deliver a therapeutic proton radiation dose attenuated via the first filter to the first portion of the patient.

公开(公告)号：US12109426B2

公开(公告)日：2024-10-08

申请号：US18182663

申请日：2023-03-13

申请人： BTL Medical Solutions A.S.

发明人： Tomás Schwarz ,  Ondra Prouza

IPC分类号： A61N2/00 ,  A61B18/20 ,  A61B90/50 ,  A61F7/00 ,  A61N1/06 ,  A61N1/40 ,  A61N2/02 ,  A61N5/06 ,  A61N7/00 ,  A61B17/00 ,  A61B18/00 ,  A61B18/22 ,  A61N5/00 ,  A61N5/067

CPC分类号： A61N2/004 ,  A61B18/203 ,  A61B90/50 ,  A61F7/00 ,  A61N1/06 ,  A61N1/40 ,  A61N2/002 ,  A61N2/02 ,  A61N5/0613 ,  A61N5/0622 ,  A61N5/0624 ,  A61N5/0625 ,  A61N7/00 ,  A61B2017/00106 ,  A61B2017/00154 ,  A61B2018/00005 ,  A61B2018/00452 ,  A61B2018/00464 ,  A61B2018/0047 ,  A61B2018/00559 ,  A61B2018/00791 ,  A61B18/22 ,  A61F2007/0022 ,  A61F2007/004 ,  A61F2007/0041 ,  A61N2/008 ,  A61N2005/005 ,  A61N5/0616 ,  A61N5/062 ,  A61N2005/0626 ,  A61N2005/0644 ,  A61N2005/0659 ,  A61N2005/066 ,  A61N2005/0661 ,  A61N2005/0662 ,  A61N2005/0663 ,  A61N5/067 ,  A61N2007/0008 ,  A61N2007/0034

摘要： A device for enhancement of visual appearance including a first applicator to be coupled to a first area of a body region, with a first magnetic field generating device and a first radiofrequency electrode, a second applicator to be coupled to a second area of the body region, with a second magnetic field generating device. The device further includes a first energy storage device, a second energy storage device, and a first switching device to discharge energy from the first energy storage device to the first magnetic field generating to generate a first time-varying magnetic field to cause muscle contraction, and a second switching to discharge energy from the second energy storage device to the second magnetic field generating device to generate a second time-varying magnetic field. The first radiofrequency electrode may provide first radiofrequency waves causing heating of tissue within the first area of the body region.

公开(公告)号：US12109425B2

公开(公告)日：2024-10-08

申请号：US15733409

申请日：2018-01-24

申请人： Hefei Institutes of Physical Science, Chinese Academy of Sciences

发明人： Kai Zhong ,  Xiaoming Zhang ,  Jin Zhang ,  Haiyang Tong ,  Hongyi Yang

IPC分类号： A61N2/02 ,  A61N2/00

CPC分类号： A61N2/004 ,  A61N2/02

摘要： A method and a device for cartilage regeneration are provided. The method for cartilage regeneration has steps of: applying a pulse magnetic field with a magnetic pulse device to a body part of a mammal in which an injured cartilage tissue is located, wherein the magnetic pulse device has a magnetic pulse generator and a coil, and by applying a magnetic pulse with a frequency of from 10 Hz to 200 Hz to the coil, a uniform magnetic field distribution is produced in a region of the body part covered by the coil, thereby achieving a uniform magnetically induced electrical excitation. The method can effectively facilitate articular cartilage regeneration, and is convenient to operate, having a broad prospect in clinical applications.

公开(公告)号：US12109419B2

公开(公告)日：2024-10-08

申请号：US17033983

申请日：2020-09-28

申请人： Peter Forsell

发明人： Peter Forsell

IPC分类号： A61M60/148 ,  A61B1/018 ,  A61B17/32 ,  A61M1/04 ,  A61M1/36 ,  A61M60/191 ,  A61M60/289 ,  A61M60/468 ,  A61M60/495 ,  A61M60/50 ,  A61M60/861 ,  A61M60/873 ,  A61M60/894 ,  A61N1/362 ,  A61N1/39

CPC分类号： A61N1/3627 ,  A61B1/018 ,  A61B17/320016 ,  A61M1/04 ,  A61M1/3627 ,  A61M60/148 ,  A61M60/191 ,  A61M60/289 ,  A61M60/468 ,  A61M60/495 ,  A61M60/50 ,  A61M60/861 ,  A61M60/873 ,  A61M60/894 ,  A61M2205/32 ,  A61M2205/33 ,  A61M2205/3303 ,  A61M2205/8243 ,  A61M2230/04 ,  A61N1/3962

摘要： The present invention relates to an implantable device for improving the pump function of the heart of a human patient by applying an external force on a first position of the heart muscle following the heart's contractions. The implantable device comprising a first pump device adapted to assist the pump function of the heart. The pump device comprises a first reservoir, a second reservoir, a fluid connection adapted to fluidly connect said first reservoir with said second reservoir, such that fluid can flow between said first reservoir and said second reservoir.