公开(公告)号：US20120296512A1

公开(公告)日：2012-11-22

申请号：US13455642

申请日：2012-04-25

申请人： Jay Lee ,  Seyed Mohammad Rezvanizaniani ,  Mohamed AbuAli ,  Yixiang Huang

发明人： Jay Lee ,  Seyed Mohammad Rezvanizaniani ,  Mohamed AbuAli ,  Yixiang Huang

IPC分类号： G01M17/00 ,  B60L11/18 ,  G06F17/00

CPC分类号： H01M10/486 ,  B60K6/48 ,  B60K35/00 ,  B60K37/06 ,  B60K2370/1442 ,  B60K2370/5899 ,  B60K2370/592 ,  B60W50/14 ,  B60W2050/146 ,  B60W2510/244 ,  B60W2510/246 ,  B60W2520/10 ,  B60W2520/105 ,  B60W2530/14 ,  B60W2550/12 ,  B60W2550/14 ,  B60W2550/402 ,  H01M10/48 ,  H01M2220/20 ,  Y02T10/6221 ,  Y02T10/6269

摘要： A system for managing mobility of an electrically-powered vehicle. The system includes a monitoring module comprising a plurality of sensors. Each of the plurality of sensors is configured to sense the status of at least one feature of each of the electrically-powered vehicle, an environment in which the electrically-powered vehicle is residing, and a state of health of a battery of the electrically-powered vehicle. A mobility analysis module estimates mobility of the electric-powered vehicle based on the sensed status, and a telematics module displays the sensed statuses, the estimated mobility, or both. The telematics module resides on a cloud-based server.

摘要翻译： 一种用于管理电动车辆的移动性的系统。 该系统包括包括多个传感器的监视模块。 多个传感器中的每一个被配置为感测电动车辆中的每一个的至少一个特征的状态，电动车辆所在的环境以及电动车辆的电池的健康状态， 动力车辆。 移动性分析模块基于感测到的状态来估计电动车辆的移动性，并且远程信息处理模块显示感测到的状态，估计的移动性或两者。 远程信息处理模块驻留在基于云的服务器上。

公开(公告)号：US20120271167A1

公开(公告)日：2012-10-25

申请号：US13409634

申请日：2012-03-01

申请人： Christy K. Holland ,  Kathryn E. Hitchcock ,  Kevin Haworth ,  Nikolas Ivancevich ,  T. Douglas Mast

发明人： Christy K. Holland ,  Kathryn E. Hitchcock ,  Kevin Haworth ,  Nikolas Ivancevich ,  T. Douglas Mast

IPC分类号： A61B8/08 ,  A61N7/00

CPC分类号： A61M37/0092 ,  A61B8/0833 ,  A61B8/481

摘要： Methods and systems for inducing and passively detecting stable cavitation and/or inertial cavitation for targeted drug delivery across a biological membrane are disclosed. Such methods include administering vesicles having a nucleating agent and a therapeutic drug to a vascular system of a patient, and providing an active interval of ultrasonic exposure substantially throughout a targeted treatment zone. The ultrasonic exposure is produced by a source transducer at a specified fundamental frequency, amplitude, duty cycle, and duration. The methods also include detecting a scattered ultrasonic wave, where the scattered ultrasonic wave is received by a detection transducer. Detection of the scattered ultrasonic wave is indicative of stable and/or inertial cavitation. The ultrasonic exposure is provided intermittently in the active intervals separated by rest periods, and substantially less ultrasonic exposure is provided during the rest period than during the active interval.

摘要翻译： 公开了用于诱导和被动检测稳定气蚀和/或惯性空化以用于横跨生物膜的靶向药物递送的方法和系统。 这样的方法包括将具有成核剂和治疗药物的囊泡给予患者的血管系统，并且基本上在整个靶向治疗区域提供超声暴露的活性间隔。 超声波曝光由源传感器以指定的基频，幅度，占空比和持续时间产生。 该方法还包括检测散射超声波，其中散射的超声波被检测传感器接收。 散射超声波的检测表明稳定和/或惯性空化。 超声波曝光以间隔隔开的活动间隔间歇地提供，并且在休止期间比在活动间隔期间提供显着更少的超声波曝光。

公开(公告)号：US08278060B2

公开(公告)日：2012-10-02

申请号：US13242288

申请日：2011-09-23

申请人： Francis X. McCormack ,  Lisa R. Young

发明人： Francis X. McCormack ,  Lisa R. Young

IPC分类号： G01N33/53

CPC分类号： G01N33/74 ,  A61B5/08 ,  A61B5/415 ,  A61B5/416 ,  A61B5/418 ,  A61B6/03 ,  G01N2333/52 ,  G01N2800/12

摘要： Described herein are methods of diagnosing lymphangioleiomyomatosis (LAM) that permits differentiating LAM from another lung disorder. Methods of treatment are also provided.

摘要翻译： 本文描述了诊断淋巴管平滑肌瘤病（LAM）的方法，其允许区分LAM与另一种肺病。 还提供了治疗方法。

公开(公告)号：US20120148813A1

公开(公告)日：2012-06-14

申请号：US12025923

申请日：2008-02-05

申请人： Anastasios Angelopoulos

发明人： Anastasios Angelopoulos

IPC分类号： B32B7/02 ,  B32B5/16 ,  B05D1/18 ,  B32B3/00 ,  B82Y30/00

CPC分类号： B82Y30/00 ,  B05D1/18 ,  B05D1/185 ,  B05D7/56 ,  B32B2255/20 ,  B32B2255/205 ,  B32B2377/00 ,  B32B2457/18 ,  H01M8/0228 ,  H01M8/1016 ,  H01M2008/1095 ,  Y10T428/24975 ,  Y10T428/25 ,  Y10T428/259 ,  Y10T428/26 ,  Y10T428/265 ,  Y10T428/269 ,  Y10T428/31504 ,  Y10T428/31678 ,  Y10T428/31725

摘要： Embodiments of a coated substrate comprise a substrate (100) and a multi-layer multi-functional nanoparticle coating (105) having a thickness of up to about 500 nm thereon. The nanoparticle coating (105) comprises an ionic polyelectrolyte layer (110), and an ionic multi-colloid layer disposed over the polyelectrolyte layer (110). The multi-colloid layer comprises hydrophilic colloid ions (130) disposed over and coupled to the polyelectrolyte layer (110), conductive colloid ions (120) disposed over and coupled to the polyelectrolyte layer (110). The conductive colloid ions (120) are separated from the hydrophilic colloid ions (130) by repulsive forces therebetween.

摘要翻译： 涂覆的基底的实施方案包括其上具有至多约500nm厚度的基底（100）和多层多功能纳米颗粒涂层（105）。 纳米颗粒涂层（105）包括离子聚电解质层（110）和设置在聚电解质层（110）上的离子多胶体层。 所述多胶体层包括设置在所述聚电解质层（110）上并耦合到所述聚电解质层（110）的亲水胶体离子（130），设置在所述聚电解质层（110）上并耦合到所述聚电解质层（110）的导电胶体离子（120）。 导电胶体离子（120）通过它们之间的排斥力与亲水胶体离子（130）分离。

公开(公告)号：US08114808B2

公开(公告)日：2012-02-14

申请号：US12635061

申请日：2009-12-10

申请人： Panagiotis G. Smirniotis ,  Hong Lu

发明人： Panagiotis G. Smirniotis ,  Hong Lu

IPC分类号： B01D53/02

CPC分类号： B01D53/62 ,  B01D53/96 ,  B01D2251/404 ,  B01D2251/602 ,  B01D2257/504 ,  B01D2259/40088 ,  B01J20/0211 ,  B01J20/041 ,  B01J20/06 ,  B01J20/28007 ,  B01J20/28057 ,  B01J20/28069 ,  B01J20/3078 ,  B01J20/3085 ,  B01J20/3483 ,  B82Y30/00 ,  Y02A50/2342 ,  Y02C10/04 ,  Y02C10/08 ,  Y10S95/90

摘要： A sorbent for the capture of carbon dioxide from a gas stream is provided, the sorbent containing calcium oxide (CaO) and at least one refractory dopant having a Tammann temperature greater than about 530° C., wherein the refractory dopant enhances resistance to sintering, thereby conserving performance of the sorbent at temperatures of at least about 530° C. Also provided are doped CaO sorbents for the capture of carbon dioxide in the presence of SO2.

摘要翻译： 提供了用于从气流捕获二氧化碳的吸附剂，所述吸附剂含有氧化钙（CaO）和至少一种具有塔曼温度大于约530℃的耐火材料掺杂剂，其中耐火材料掺杂物增强了耐烧结性， 从而在至少约530℃的温度下保持吸附剂的性能。还提供了用于在SO 2存在下捕获二氧化碳的掺杂的CaO吸附剂。

公开(公告)号：US08058018B2

公开(公告)日：2011-11-15

申请号：US12879729

申请日：2010-09-10

申请人： Francis X. McCormack ,  Lisa R. Young

发明人： Francis X. McCormack ,  Lisa R. Young

IPC分类号： G01N33/53

CPC分类号： G01N33/74 ,  A61B5/08 ,  A61B5/415 ,  A61B5/416 ,  A61B5/418 ,  A61B6/03 ,  G01N2333/52 ,  G01N2800/12

摘要： Described herein are methods of diagnosing lymphangioleiomyomatosis (LAM) that permits differentiating LAM from another lung disorder. Methods of treatment are also provided.

摘要翻译： 本文描述了诊断淋巴管平滑肌瘤病（LAM）的方法，其允许区分LAM与另一种肺病。 还提供了治疗方法。

公开(公告)号：US08050409B2

公开(公告)日：2011-11-01

申请号：US11098250

申请日：2005-04-04

申请人： Dharma P. Agrawal ,  Hongmei Deng ,  Anindo Mukherjee

发明人： Dharma P. Agrawal ,  Hongmei Deng ,  Anindo Mukherjee

IPC分类号： H04L9/08

CPC分类号： H04L63/06 ,  H04L9/083 ,  H04L9/085 ,  H04L9/30 ,  H04L9/321 ,  H04L9/3263 ,  H04L9/3271 ,  H04L63/08 ,  H04L2209/80 ,  H04W12/04 ,  H04W12/06 ,  H04W84/18

摘要： As various applications of wireless ad hoc network have been proposed, security has become one of the big research challenges and is receiving increasing attention. The present invention provides for a distributed key management and authentication approach by deploying the recently developed concepts of identity-based cryptography and threshold secret sharing. Without any assumption of pre-fixed trust relationship between nodes, the ad hoc network works in a self-organizing way to provide the key generation and key management service, which effectively solves the problem of single point of failure in the traditional public key infrastructure (PKI)-supported system. The identity-based cryptography mechanism provided not only to provide end-to-end authenticity and confidentiality, but also saves network bandwidth and computational power of wireless nodes.

公开(公告)号：US07927873B2

公开(公告)日：2011-04-19

申请号：US10596522

申请日：2004-12-20

申请人： Theresa M. Reineke

发明人： Theresa M. Reineke

IPC分类号： C12N15/00 ,  A61K48/00 ,  A61K31/715 ,  A61K31/44

CPC分类号： C12N15/113 ,  C12N2310/13 ,  C12N2310/51

摘要： The present invention provides a new class of non-viral transduction vectors that can be used for both in vivo and in vitro applications. The present invention also provides a gene transfer vector that has comparable efficiency to a viral vector without the potential for a life-threatening immune response. Complexes according to the invention or portions thereof, can comprise a cellular delivery molecule or agent that can facilitate the translocation of the complex or portion thereof into cells. In some embodiments, cellular delivery molecules for use in the present invention may comprise one or more polymers of the present invention, e.g., polyamides, dendritic macromolecules and carbohydrate-containing degradable polyesters.

摘要翻译： 本发明提供了可用于体内和体外应用的新一类非病毒转导载体。 本发明还提供了具有与病毒载体相当的效率而不具有危及生命的免疫应答潜力的基因转移载体。 根据本发明或其部分的复合物可以包含可以促进复合物或其部分转运到细胞中的细胞递送分子或试剂。 在一些实施方案中，用于本发明的细胞递送分子可以包含一种或多种本发明的聚合物，例如聚酰胺，树枝状大分子和含碳水化合物的可降解聚酯。

公开(公告)号：US07833805B2

公开(公告)日：2010-11-16

申请号：US11454569

申请日：2006-06-16

申请人： John Cuppoletti

发明人： John Cuppoletti

IPC分类号： C12M1/00 ,  C12M1/34 ,  G01N33/543 ,  B32B3/26 ,  B01L99/00

CPC分类号： B01D69/10 ,  B01D69/144 ,  B01D71/06 ,  H01B1/122 ,  H01M8/16 ,  H01M2300/0082 ,  H01M2300/0094 ,  Y02E60/527 ,  Y02P70/56 ,  Y10T428/249953

摘要： Functional biological synthetic composite (BSC) membranes comprising phospholipids, biological membrane proteins and porous supports or membranes are provided. Lipid bilayers are formed on porous polycarbonate (PC), polyethylene terephthalate (PETE) and poly (I-lactic acid) (PLLA) membranes and in laser-drilled pores in a multi-well plastic plate as measured by increased resistance or decreased currents. BSC's comprising functional reconstituted Kv1.5 K channel and/or H/K ATPase transport proteins are also provided c inhibitor), methods of manufacture, and high throughput screening assays employing the inventive membranes are also provided.

摘要翻译： 提供了包含磷脂，生物膜蛋白质和多孔载体或膜的功能性生物合成复合物（BSC）膜。 在多孔聚碳酸酯（PC），聚对苯二甲酸乙二醇酯（PETE）和聚（l-乳酸）（PLLA）膜上形成脂质双层，并在多孔塑料板中的激光钻孔中形成电阻增加或电流降低测量。 还提供包含功能重构的Kv1.5K通道和/或H / K ATP酶转运蛋白的BSC，c抑制剂），使用本发明的膜的制备方法和高通量筛选测定。

公开(公告)号：US20100263723A1

公开(公告)日：2010-10-21

申请号：US12669579

申请日：2008-07-21

申请人： Steven C. Allen ,  Andrew J. Steckl

发明人： Steven C. Allen ,  Andrew J. Steckl

IPC分类号： H01L31/0232 ,  H01L33/50 ,  H01L33/44 ,  H01J1/62 ,  C09K11/08 ,  C09K11/56 ,  C09K11/67 ,  C09K11/54

CPC分类号： C09K11/02 ,  C03C14/006 ,  C03C2214/16 ,  C09K11/7774 ,  H01L33/501 ,  H01L33/505 ,  H01L33/54 ,  H01S5/0092

摘要： A light emitting composite material (40) comprising a glassy material (44) and a phosphor (14) suspended in the glassy material (44), wherein the refractive index of the phosphor (14) is approximately equal to the refractive index of the glass material. The light emitting composite material (40) can be used in phosphor-containing light emitting devices, solid-state laser (64) diodes, and as a luminescence collector (90).

摘要翻译： 1.一种发光复合材料（40），其包含悬浮在所述玻璃状材料（44）中的玻璃质材料（44）和荧光体（14），其中，所述荧光体（14）的折射率近似等于所述玻璃 材料。 发光复合材料（40）可以用于含荧光体的发光器件，固态激光器（64）二极管和发光集电体（90）中。