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104 条记录 (耗时 0.041 秒)

    Methods for collagen processing and products using processed collagen
    81.
    发明授权
    Methods for collagen processing and products using processed collagen 有权
    胶原加工方法和使用加工胶原的产品

    公开(公告)号：US09056151B2

    公开(公告)日：2015-06-16

    申请号：US11673972

    申请日：2007-02-12

    申请人： Nels J. Lauritzen ,  Lawrence A. Shimp

    发明人： Nels J. Lauritzen ,  Lawrence A. Shimp

    IPC分类号： A61L15/32 ,  A61L27/54 ,  A61L27/24 ,  A61L27/34

    CPC分类号： A61L27/54 ,  A61L15/325 ,  A61L27/24 ,  A61L27/34 ,  A61L2300/00

    摘要： Purifying human derived collagen from human tissue includes treating harvested human tissue with an enzyme to form a collagen product, deactivating the enzyme with a non-alkaline enzyme deactivation solution, and collecting the collagen product resulting from the enzyme treatment, where the collected collagen product includes a preserved amount of its natural collagen constituents. Various medical implants can be formed using the isolated, enzymatically-treated human derived collagen having an amount of its natural collagen constituents preserved, and may include implantable sponges, patches, tubes, structural supports and coatings, and which may be used for repair, barrier, support and/or stabilization purposes.

    摘要翻译： 从人体组织中纯化人源胶原蛋白包括用酶处理收获的人体组织以形成胶原产物，用非碱性酶失活溶液使酶失活，以及收集由酶处理产生的胶原产物，其中所收集的胶原产品包括 保留量的天然胶原成分。 可以使用分离的，经酶处理的人源胶原蛋白形成各种医学植入物，其具有保存的天然胶原成分的量，并且可以包括可植入的海绵，贴剂，管，结构载体和涂层，并且其可用于修复，屏障 ，支持和/或稳定目的。

    Foam-formed collagen strand
    83.
    发明授权
    Foam-formed collagen strand 有权
    泡沫形成的胶原链

    公开(公告)号：US08790699B2

    公开(公告)日：2014-07-29

    申请号：US12766422

    申请日：2010-04-23

    申请人： Nels Lauritzen ,  Lawrence A. Shimp ,  Brent Mitchell

    发明人： Nels Lauritzen ,  Lawrence A. Shimp ,  Brent Mitchell

    IPC分类号： A61K38/39 ,  A61K35/00 ,  A61P19/04 ,  A61K38/18 ,  A61P17/02 ,  A61K9/10 ,  B05D3/00

    CPC分类号： C07K14/78 ,  A61K9/0021 ,  A61K9/122 ,  A61K47/42 ,  A61L17/08 ,  A61L27/24 ,  A61L27/56 ,  C08J9/28 ,  C08J2201/0484 ,  C08J2389/00

    摘要： Foam-formed collagen strands and methods for forming strands involve depositing a dispersed solution of an isolated cleaned, de-fatted, enzymatically-treated (or non-enzyme treated) human-derived collagen product having a preserved amount of its natural constituents into grooves of a grooved plate, and processing the dispersed collagen product to provide a foam-formed collagen strand. Foam-formed collagen strands may be processed into threads having a matrix of reticulated pores to conduct biological materials in and through the strand, the collagen of the collagen strand comprising isolated, enzymatically-treated human derived collagen having a preserved amount of its natural collagen constituents.

    摘要翻译： 泡沫形成的胶原链和用于形成链的方法包括将具有保留量的其天然成分的分离的清除，脱脂，酶处理（或非酶处理）的人源胶原产品的分散溶液沉积在 开槽板，并处理分散的胶原产品以提供泡沫形成的胶原链。 泡沫形成的胶原链可以被加工成具有网状孔基质的丝线，以在该链中进行生物材料，该胶原链的胶原包含分离的，经酶处理的人源胶原，其具有保留量的其天然胶原成分 。

    Fenestrated wound repair scaffold
    86.
    发明授权
    Fenestrated wound repair scaffold 有权
    开窗伤口修复脚手架

    公开(公告)号：US08460691B2

    公开(公告)日：2013-06-11

    申请号：US12766494

    申请日：2010-04-23

    申请人： Nels Lauritzen ,  Lawrence A. Shimp ,  Brent Mitchell

    发明人： Nels Lauritzen ,  Lawrence A. Shimp ,  Brent Mitchell

    IPC分类号： A61F2/02 ,  A61P17/02

    CPC分类号： A61L27/60 ,  A61K38/39 ,  A61L27/24 ,  A61L27/56

    摘要： Fenestrated wound repair scaffolds and methods for forming scaffolds involve dispersing human collagen having a preserved amount of native constituents in solution, depositing the human collagen dispersion in a tray, forming openings in the collagen dispersion and removing the liquid component to form a fenestrated wound repair scaffold. Fenestrated wound repair scaffolds include a network of openings passing linearly through the wound repair scaffold to form channels for cells to pass into so as to form a series of cell formations therein.

    摘要翻译： 开窗修复支架和形成支架的方法包括将具有保留量的天然成分的人胶原分散在溶液中，将人胶原分散体沉积在托盘中，在胶原分散体中形成开口并除去液体组分以形成开窗伤口修复支架 。 开窗伤口修复支架包括通过伤口修复支架线性通过的开口网，以形成细胞通过的通道，以在其中形成一系列细胞结构。

    FOAM-FORMED COLLAGEN STRAND
    88.
    发明申请
    FOAM-FORMED COLLAGEN STRAND 有权
    泡沫形成的胶原条

    公开(公告)号：US20110262541A1

    公开(公告)日：2011-10-27

    申请号：US12766422

    申请日：2010-04-23

    申请人： Nels Lauritzen ,  Lawrence A. Shimp ,  Brent Mitchell

    发明人： Nels Lauritzen ,  Lawrence A. Shimp ,  Brent Mitchell

    IPC分类号： A61K38/39 ,  A61K35/00 ,  A61P19/04 ,  A61K38/18 ,  A61P17/02 ,  A61K9/10 ,  B05D3/00

    CPC分类号： C07K14/78 ,  A61K9/0021 ,  A61K9/122 ,  A61K47/42 ,  A61L17/08 ,  A61L27/24 ,  A61L27/56 ,  C08J9/28 ,  C08J2201/0484 ,  C08J2389/00

    摘要： Foam-formed collagen strands and methods for forming strands involve depositing a dispersed solution of an isolated cleaned, de-fatted, enzymatically-treated (or non-enzyme treated) human-derived collagen product having a preserved amount of its natural constituents into grooves of a grooved plate, and processing the dispersed collagen product to provide a foam-formed collagen strand. Foam-formed collagen strands may be processed into threads having a matrix of reticulated pores to conduct biological materials in and through the strand, the collagen of the collagen strand comprising isolated, enzymatically-treated human derived collagen having a preserved amount of its natural collagen constituents.

    摘要翻译： 泡沫形成的胶原链和用于形成链的方法包括将具有保留量的其天然成分的分离的清除，脱脂，酶处理（或非酶处理）的人源胶原产品的分散溶液沉积在 开槽板，并处理分散的胶原产品以提供泡沫形成的胶原链。 泡沫形成的胶原链可以被加工成具有网状孔基质的丝线，以在该链中进行生物材料，该胶原链的胶原包含分离的，经酶处理的人源胶原，其具有保留量的其天然胶原成分 。