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130 条记录 (耗时 0.042 秒)

    Intraocular, accommodating lens and methods of use
    84.
    发明授权
    Intraocular, accommodating lens and methods of use 有权
    眼内镜，适配镜片及使用方法

    公开(公告)号：US08715346B2

    公开(公告)日：2014-05-06

    申请号：US13858647

    申请日：2013-04-08

    申请人： Eugene de Juan, Jr. ,  Stephen Boyd ,  Hanson Gifford ,  Cary Reich

    发明人： Eugene de Juan, Jr. ,  Stephen Boyd ,  Hanson Gifford ,  Cary Reich

    IPC分类号： A61F2/16

    CPC分类号： A61F2/1694 ,  A61F2/1635 ,  A61F2/1648 ,  A61F2002/1682 ,  A61F2210/0019

    摘要： An intraocular lens is adapted for insertion into a capsular bag having a zonular contact region. The intraocular lens comprises a shape changing optical element and an accommodating element comprising at least one force transmitting element and a plurality of spaced apart contacting elements each adapted to contact a portion of the zonular contact region and transmit compressive displacement radially inward at an oblique angle to the optical element and configured to cooperate with at least one of the ciliary muscle of the mammalian eye, the zonules of the mammalian eye and the vitreous pressure in the eye to effect an accommodating shape and a disaccommodating shape change to the optical element.

    摘要翻译： 眼内透镜适于插入具有区域接触区域的囊袋中。 所述眼内透镜包括形状改变光学元件和容纳元件，所述容纳元件包括至少一个力传递元件和多个间隔开的接触元件，每个接触元件适于接触所述区域接触区域的一部分，并以 所述光学元件被配置为与哺乳动物眼睛的睫状肌，哺乳动物眼睛的小环和眼睛中的玻璃体压力中的至少一个配合，以实现对光学元件的适应形状和不适应的形状的变化。

    Methods for treating heart arrhythmia
    89.
    发明申请
    Methods for treating heart arrhythmia 审中-公开
    治疗心律失常的方法

    公开(公告)号：US20070129761A1

    公开(公告)日：2007-06-07

    申请号：US11599882

    申请日：2006-11-14

    申请人： Denise Demarais ,  Hanson Gifford

    发明人： Denise Demarais ,  Hanson Gifford

    IPC分类号： A61N1/00

    CPC分类号： A61M25/0084 ,  A61B17/3478 ,  A61B18/04 ,  A61B18/1492 ,  A61B2018/0022 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61B2018/00577 ,  A61F7/007 ,  A61K38/4893 ,  A61M5/00 ,  A61M2025/0085 ,  A61M2202/0007 ,  A61M2210/1082 ,  A61N1/05 ,  A61N1/0551 ,  A61N1/32 ,  A61N1/36017 ,  A61N1/36114 ,  A61N7/02 ,  C12Y304/24069

    摘要： Methods and apparatus are provided for treatment of heart arrhythmia via renal neuromodulation. Such neuromodulation may effectuate irreversible electroporation or electrofusion, ablation, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or blockade, changes in cytokine up-regulation and other conditions in target neural fibers. In some embodiments, such neuromodulation is achieved through application of an electric field. In some embodiments, such neuromodulation is achieved through application of neuromodulatory agents, of thermal energy and/or of high intensity focused ultrasound. In some embodiments, such neuromodulation is performed in a bilateral fashion.

    摘要翻译： 提供了通过肾脏神经调节治疗心律失常的方法和装置。 这种神经调节可以实现不可逆的电穿孔或电融合，消融，坏死和/或诱导凋亡，基因表达的改变，动作电位衰减或阻断，细胞因子上调的变化和靶神经纤维中的其它条件。 在一些实施例中，通过施加电场来实现这种神经调节。 在一些实施方案中，通过应用神经调节剂，热能和/或高强度聚焦超声来实现这种神经调节。 在一些实施方案中，这种神经调节以双向方式进行。

    Systems and methods for delivering fastener to opposed tissue structures
    90.
    发明申请
    Systems and methods for delivering fastener to opposed tissue structures 审中-公开
    将紧固件递送到相对的组织结构的系统和方法

    公开(公告)号：US20060106405A1

    公开(公告)日：2006-05-18

    申请号：US11274791

    申请日：2005-11-15

    申请人： James Fann ,  Hanson Gifford

    发明人： James Fann ,  Hanson Gifford

    IPC分类号： A61B17/10

    CPC分类号： A61B17/11 ,  A61B17/0644 ,  A61B17/1285 ,  A61B2017/0641 ,  A61B2017/0647 ,  A61B2017/0649 ,  A61B2017/1103 ,  A61B2017/1107 ,  A61B2017/1135

    摘要： Flexible clips which are transported over a solid needle or through a hollow needle and methods of use thereof are described for tissue approximation and attachment and for joining a graft vessel to a target vessel. The tissue approximation or anastomosis clip includes a highly flexible or elastic material wrapped around and transported on the outside of a solid needle. Another embodiment is a flexible or composite clip which is transported within a hollow needle. The distal end of the clips has a tapered configuration to minimize resistance and facilitate tissue penetration. After placement of the clip in the desired location, the solid or hollow needle is withdrawn resulting in coiling or contraction of the clip thus approximating the tissue and securing the clip. Multiple clips can be loaded in the deployment device which is calibrated to deploy and secure one clip at a time. An additional embodiment is a needle point attached to a clip that overrides a solid shaft. Deployment is by pushing or displacing the clip portion from the shaft. A plurality of these needle-clips may be oriented on a circular ring which permits rapid clip deployment and tissue approximation, such as for anastomosis, and methods for subsequent ring removal or dismantling.

    摘要翻译： 描述了通过固体针或通过中空针运送的柔性夹子及其使用方法用于组织近似和附接并用于将移植血管连接到靶容器。 组织近似或吻合夹包括在固体针的外侧缠绕并运输的高度柔性或弹性的材料。 另一个实施例是在中空针内输送的柔性或复合夹子。 夹子的远端具有锥形构型以最小化阻力并促进组织穿透。 在将夹子放置在所需位置之后，将固体或中空针抽出，导致夹子的卷绕或收缩，从而近似组织并固定夹子。 多个剪辑可以加载到部署设备中，该设备被校准为一次部署和保护一个剪辑。 附加的实施例是附接到夹子的针尖，其覆盖实心轴。 部署是通过推动或移动夹子部分从轴。 多个这些针夹可以定向在圆形环上，其允许快速夹子展开和组织近似，例如用于吻合，以及用于随后的环移除或拆除的方法。