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公开(公告)号：US10204772B2
公开(公告)日：2019-02-12
申请号：US15902068
申请日：2018-02-22
Applicant: Purdue Research Foundation
Inventor： Robert Graham Cooks , Ahmed Mohamed Hamid , Alan Keith Jarmusch , Zheng Ouyang
Abstract: The invention generally relates to systems and methods for mass spectrometry analysis of microorganisms in samples.
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公开(公告)号：US20180372699A1
公开(公告)日：2018-12-27
申请号：US16107296
申请日：2018-08-21
Applicant: Purdue Research Foundation
Inventor： Robert Graham Cooks , Zheng Ouyang
Abstract: The invention generally relates to ion generation using modified wetted porous materials. In certain aspects, the invention generally relates to systems and methods for ion generation using a wetted porous substrate that substantially prevents diffusion of sample into the substrate. In other aspects, the invention generally relate to ion generation using a wetted porous material and a drying agent. In other aspects, the invention generally relates to ion generation using a modified wetted porous substrate in which at least a portion of the porous substrate includes a material that modifies an interaction between a sample and the substrate.
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公开(公告)号：US20180279927A1
公开(公告)日：2018-10-04
申请号：US15989706
申请日：2018-05-25
Applicant: Purdue Research Foundation
Inventor： Robert Graham Cooks , Zheng Ouyang , Chien-Hsun Chen , Ziqing Lin , Livia Schiavinato Eberlin
IPC: A61B5/1477 , G01N33/483 , A61B10/00 , A61M11/00 , A61M25/00 , H01J49/00 , H01J49/04 , H01J49/16
CPC classification number: A61B5/1477 , A61B5/1405 , A61B5/145 , A61B5/150015 , A61B5/150992 , A61B5/157 , A61B10/0045 , A61M11/00 , A61M25/00 , A61M2202/0468 , G01N33/4833 , G01N2001/028 , H01J49/0022 , H01J49/0404 , H01J49/0445 , H01J49/167 , H01J49/34
Abstract: The invention generally relates to enclosed desorption electrospray ionization probes, systems, and methods. In certain embodiments, the invention provides a source of DESI-active spray, in which a distal portion of the source is enclosed within a transfer member such that the DESI-active spray is produced within the transfer member.
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公开(公告)号：US10088461B2
公开(公告)日：2018-10-02
申请号：US15710072
申请日：2017-09-20
Applicant: Purdue Research Foundation
Inventor： Robert Graham Cooks , Zheng Ouyang
Abstract: The invention generally relates to ion generation using modified wetted porous materials. In certain aspects, the invention generally relates to systems and methods for ion generation using a wetted porous substrate that substantially prevents diffusion of sample into the substrate. In other aspects, the invention generally relate to ion generation using a wetted porous material and a drying agent. In other aspects, the invention generally relates to ion generation using a modified wetted porous substrate in which at least a portion of the porous substrate includes a material that modifies an interaction between a sample and the substrate.
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公开(公告)号：US10004440B2
公开(公告)日：2018-06-26
申请号：US15617013
申请日：2017-06-08
Applicant: Purdue Research Foundation
Inventor： Robert Graham Cooks , Zheng Ouyang , Chien-Hsun Chen , Ziqing Lin , Livia Schiavinato Eberlin
IPC: H01J49/00 , A61B5/1477 , H01J49/16 , H01J49/34 , A61M25/00 , G01N33/483 , H01J49/04 , A61M11/00
Abstract: The invention generally relates to enclosed desorption electrospray ionization probes, systems, and methods. In certain embodiments, the invention provides a source of DESI-active spray, in which a distal portion of the source is enclosed within a transfer member such that the DESI-active spray is produced within the transfer member.
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Patent Agency Ranking
公开(公告)号：US20180017535A1
公开(公告)日：2018-01-18
申请号：US15710072
申请日：2017-09-20
Applicant: Purdue Research Foundation
Inventor： Robert Graham Cooks , Zheng Ouyang
CPC classification number: G01N30/95 , G01N30/91 , G01N33/49 , H01J49/0031 , H01J49/0404 , H01J49/0409 , H01J49/0431 , H01J49/167 , H01J49/168
Abstract: The invention generally relates to ion generation using modified wetted porous materials. In certain aspects, the invention generally relates to systems and methods for ion generation using a wetted porous substrate that substantially prevents diffusion of sample into the substrate. In other aspects, the invention generally relate to ion generation using a wetted porous material and a drying agent. In other aspects, the invention generally relates to ion generation using a modified wetted porous substrate in which at least a portion of the porous substrate includes a material that modifies an interaction between a sample and the substrate.
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公开(公告)号：US20180012746A1
公开(公告)日：2018-01-11
申请号：US15548275
申请日：2016-02-08
Applicant: Zheng OUYANG , Yue REN , Xiao WANG , Purdue Research Foundation
Inventor： Zheng Ouyang , Yue Ren , Xiao Wang
IPC: H01J49/04
CPC classification number: H01J49/0409 , H01J49/0445 , H01J49/167
Abstract: The invention generally relates to probes, systems, cartridges, and methods of use thereof. In certain embodiments, the invention provides a probe including a porous material and a hollow member coupled to a distal portion of the porous material.
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公开(公告)号：US20170135613A1
公开(公告)日：2017-05-18
申请号：US15400358
申请日：2017-01-06
Applicant: Purdue Research Foundation
Inventor： Robert Graham Cooks , Zheng Ouyang , Chien-Hsun Chen , Ziqing Lin , Livia Schiavinato Eberlin
IPC: A61B5/1477 , A61M25/00 , H01J49/34 , H01J49/00 , H01J49/04 , H01J49/16 , A61M11/00 , G01N33/483
CPC classification number: A61B5/1477 , A61B5/1405 , A61B5/145 , A61B5/150015 , A61B5/150992 , A61B5/157 , A61B10/0045 , A61M11/00 , A61M25/00 , A61M2202/0468 , G01N33/4833 , G01N2001/028 , H01J49/0022 , H01J49/0404 , H01J49/0445 , H01J49/167 , H01J49/34
Abstract: The invention generally relates to enclosed desorption electrospray ionization probes, systems, and methods. In certain embodiments, the invention provides a source of DESI-active spray, in which a distal portion of the source is enclosed within a transfer member such that the DESI-active spray is produced within the transfer member.
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公开(公告)号：US09484195B2
公开(公告)日：2016-11-01
申请号：US14880613
申请日：2015-10-12
Applicant: Purdue Research Foundation
Inventor： Zheng Ouyang , Robert Graham Cooks , Sandilya Venkata Garimella , Jason David Harper , Nicholas Alan Charipar
CPC classification number: H01J49/0404 , G01N27/622 , H01J49/0027 , H01J49/0031 , H01J49/04 , H01J49/0409 , H01J49/0422 , H01J49/0459 , H01J49/10 , H01J49/26 , H01J49/40 , H01J49/4215
Abstract: The invention generally relates to systems and methods for transferring ions for analysis. In certain embodiments, the invention provides a system for analyzing a sample including an ionizing source for converting molecules of a sample into gas phase ions in a region at about atmospheric pressure, an ion analysis device, and an ion transfer member operably coupled to a gas flow generating device, in which the gas flow generating device produces a laminar gas flow that transfers the gas phase ions through the ion transfer member to an inlet of the ion analysis device.
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公开(公告)号：US09230792B2
公开(公告)日：2016-01-05
申请号：US14512579
申请日：2014-10-13
Applicant: Purdue Research Foundation
Inventor： Robert Graham Cooks , Zheng Ouyang , Zhiping Zhang
CPC classification number: G01N30/95 , G01N30/91 , G01N33/49 , H01J49/0031 , H01J49/0404 , H01J49/0409 , H01J49/0431 , H01J49/167 , H01J49/168
Abstract: The invention generally relates to ion generation using modified wetted porous materials. In certain aspects, the invention generally relates to systems and methods for ion generation using a wetted porous substrate that substantially prevents diffusion of sample into the substrate. In other aspects, the invention generally relate to ion generation using a wetted porous material and a drying agent. In other aspects, the invention generally relates to ion generation using a modified wetted porous substrate in which at least a portion of the porous substrate includes a material that modifies an interaction between a sample and the substrate.
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