公开(公告)号：US06305378B1

公开(公告)日：2001-10-23

申请号：US09384727

申请日：1999-08-27

申请人： Michael D. Lesh

发明人： Michael D. Lesh

IPC分类号： A61B1900

CPC分类号： A61B18/10 ,  A61B18/08 ,  A61B18/1492 ,  A61B18/1815 ,  A61B2017/00243 ,  A61B2017/22038 ,  A61B2017/22054 ,  A61B2017/22067 ,  A61B2018/00011 ,  A61B2018/00083 ,  A61B2018/00107 ,  A61B2018/00148 ,  A61B2018/0016 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00273 ,  A61B2018/00285 ,  A61B2018/00291 ,  A61B2018/00351 ,  A61B2018/00369 ,  A61B2018/00375 ,  A61B2018/00577 ,  A61B2018/00642 ,  A61B2018/00797 ,  A61B2018/00815 ,  A61B2018/00821 ,  A61B2018/00839 ,  A61B2018/00898 ,  A61B2018/00994 ,  A61B2018/1407 ,  A61B2218/002 ,  A61M25/1002 ,  A61M2025/1075 ,  A61M2210/125 ,  A61N7/022

摘要： This invention is a method for treating a patient diagnosed with atrial arrhythmia by forming a circumferential conduction block along a circumferential path of tissue in a pulmonary vein wall that circumscribes the pulmonary vein lumen and transects the electrical conductivity of the pulmonary vein such that conduction is blocked along the longitudinal axis of the vein wall and into the left atrial wall. The method is performed to treat a patient with a focal arrythmogenic origin along the pulmonary vein wall by either ablating the focal origin or by isolating the focal origin from the atrial wall with the circumferential conduction block. The circumferential conduction block is also formed in a pulmonary vein in order to bridge the adjacent ends of two linear lesions, wherein each linear lesion is formed to extend between the pulmonary vein and another adjacent pulmonary vein in a less-invasive “maze”-type procedure. A circumferential ablation element in a circumferential ablation device assembly is used in a percutaneous translumenal catheter technique in order to form the circumferential conduction block in the pulmonary vein wall.

摘要翻译： 本发明是一种通过沿着肺静脉壁的肺组织周向路径形成圆周传导阻滞来诊断患有心律失常的患者的方法，所述肺静脉壁围绕肺静脉管腔并横切肺静脉的导电性从而导致阻塞 沿着静脉壁的纵向轴线并进入左心房壁。 执行该方法以通过消融焦点来源或通过用圆周传导阻滞来将心源起点与心房壁一起沿着肺静脉壁治疗具有局灶性原发性起源的患者。 圆周传导阻滞也形成在肺静脉中以便桥接两个线性损伤的相邻端，其中每个线性病变形成为在较小侵入性“迷宫”型的肺静脉和另一相邻的肺静脉之间延伸 程序。 在经皮腔内导管技术中使用周缘消融装置组件中的圆周消融元件，以便在肺静脉壁中形成圆周传导阻滞。

公开(公告)号：US06254599B1

公开(公告)日：2001-07-03

申请号：US09273815

申请日：1999-03-22

申请人： Michael D. Lesh ,  Michael Ronald Ross ,  Jonathan J. Langberg ,  James C. Peacock, III

发明人： Michael D. Lesh ,  Michael Ronald Ross ,  Jonathan J. Langberg ,  James C. Peacock, III

IPC分类号： A61B1818

CPC分类号： A61B18/1492 ,  A61B18/00 ,  A61B18/1815 ,  A61B2017/00243 ,  A61B2017/22038 ,  A61B2017/22054 ,  A61B2017/22067 ,  A61B2018/00011 ,  A61B2018/0016 ,  A61B2018/00214 ,  A61B2018/00273 ,  A61B2018/00285 ,  A61B2018/00291 ,  A61B2018/00369 ,  A61B2018/00375 ,  A61B2018/00797 ,  A61B2018/00815 ,  A61B2018/00821 ,  A61B2018/00839 ,  A61B2018/00898 ,  A61B2018/00994 ,  A61B2218/002 ,  A61N7/02

摘要： This invention is a circumferential ablation device assembly which is adapted to forming a circumferential conduction block in a pulmonary vein. The assembly includes a circumferential ablation element which is adapted to ablate a circumferential region of tissue along a pulmonary vein wall which circumscribes the pulmonary vein lumen, thereby transecting the electrical conductivity of the pulmonary vein against conduction along its longitudinal axis and into the left atrium. The circumferential ablation element includes an expandable member with a working length that is adjustable from a radially collapsed position to a radially expanded position. An equatorial band circumscribes the outer surface of the working length and is adapted to ablate tissue adjacent thereto when actuated by an ablation actuator. The equatorial band has a length relative to the longitudinal axis of the expandable member that is narrow relative to the working length, and is also substantially shorter than its circumference when the working length is in the radially expanded position. A pattern of insulators may be included over an ablation element which otherwise spans the working length in order to form the equatorial band described. The expandable member is also adapted to conform to the pulmonary vein in the region of its ostium, such as by providing a great deal of radial compliance or by providing a taper along the working length which has a distally reducing outer diameter. A linear ablation element is provided adjacent to the circumferential ablation element in a combination assembly which is adapted for use in a less-invasive “maze”-type procedure in the region of the pulmonary vein ostia in the left ventricle.

公开(公告)号：US6086582A

公开(公告)日：2000-07-11

申请号：US816850

申请日：1997-03-13

申请人： Peter A. Altman ,  John D. Altman

发明人： Peter A. Altman ,  John D. Altman

IPC分类号： A61B17/00 ,  A61B18/14 ,  A61B18/18 ,  A61K9/127 ,  A61K9/16 ,  A61K9/50 ,  A61M5/178 ,  A61M25/00 ,  A61N1/05

CPC分类号： A61B18/1492 ,  A61K9/127 ,  A61K9/1676 ,  A61K9/50 ,  A61N1/0575 ,  B82Y5/00 ,  A61B2017/00247 ,  A61B2018/00011 ,  A61B2018/00273 ,  A61B2018/00351 ,  A61B2018/00392 ,  A61B2018/00577 ,  A61B2018/00839 ,  A61B2018/1425 ,  A61B2018/1435 ,  A61B2218/002 ,  A61M2025/0089 ,  A61M25/0084

摘要： A system is disclosed, for administering a therapeutic agent locally and to a depth within cardiac tissue. An elongate, flexible catheter contains a flexible electric conductor and supports at its distal end an implantable electrode incorporating a penetrating element, typically a fixation helix or a linear needle that penetrates cardiac tissue as the electrode is implanted. A therapeutic agent is delivered through the electrode, to the cardiac tissue surrounding the penetrating element. The electrode acts as a sensor, electrically coupled through the flexible conductor, and monitors an electrical condition of the surrounding cardiac tissue. A controller is coupled to the sensor and to a pump or reservoir containing the therapeutic agent, to control delivery of the agent responsive to the sensed electrical condition. The implanted electrode further can be used to deliver RF current to ablate the surrounding tissue. Several embodiments feature a distal reservoir adjacent the electrode, for effecting transient deliveries of the therapeutic agent in minute quantities or chronic delivery of growth factors. Another embodiment incorporates a bilumen catheter and a set of unidirectional valves, to facilitate changing therapeutic agents or purging the catheter of an agent after delivery.

公开(公告)号：US6056743A

公开(公告)日：2000-05-02

申请号：US35625

申请日：1998-03-05

申请人： Louis Ellis ,  Daniel M. Lafontaine ,  Roger N. Hastings ,  Lauri DeVore

发明人： Louis Ellis ,  Daniel M. Lafontaine ,  Roger N. Hastings ,  Lauri DeVore

IPC分类号： A61B19/00 ,  A61B6/00 ,  A61B17/00 ,  A61B17/22 ,  A61B17/32 ,  A61B17/34 ,  A61B18/00 ,  A61B18/02 ,  A61B18/12 ,  A61B18/14 ,  A61B17/36

CPC分类号： A61B17/3207 ,  A61B18/1492 ,  A61B2017/00247 ,  A61B2017/22077 ,  A61B2017/3488 ,  A61B2018/00273 ,  A61B2018/00291 ,  A61B2018/00392 ,  A61B2018/144 ,  A61B2090/395 ,  A61B90/39 ,  A61M2210/125

摘要： Devices and methods for creating a series of percutaneous myocardial revascularization (PMR) channels in the heart. One method includes forming a pattern of channels in the myocardium leading from healthy tissue to hibernating tissue. Suitable channel patterns include lines and arrays. One method includes anchoring a radiopaque marker to a position in the ventricle wall, then using fluoroscopy repeatedly to guide positioning of a cutting tip in the formation of multiple channels. Another method uses radiopaque material injected into each channel formed, as a marker. Yet another method utilizes an anchorable, rotatable cutting probe for channel formation about an anchor member, where the cutting probe can vary in radial distance from the anchor. Still another method utilizes a multiple wire radio frequency burning probe, for formation of multiple channels simultaneously. Still another method utilizes liquid nitrogen to cause localized tissue death.

公开(公告)号：US5842984A

公开(公告)日：1998-12-01

申请号：US968159

申请日：1997-11-12

申请人： Boaz Avitall

发明人： Boaz Avitall

IPC分类号： A61B5/042 ,  A61B18/00 ,  A61B18/14 ,  A61N1/06 ,  A61B5/04 ,  A61N1/05

CPC分类号： A61B5/0422 ,  A61B18/1492 ,  A61B5/6855 ,  A61B5/6856 ,  A61B5/6859 ,  A61N1/06 ,  A61B18/14 ,  A61B18/1815 ,  A61B2017/22038 ,  A61B2018/00011 ,  A61B2018/00023 ,  A61B2018/00029 ,  A61B2018/00077 ,  A61B2018/00148 ,  A61B2018/0016 ,  A61B2018/00196 ,  A61B2018/00273 ,  A61B2018/00351 ,  A61B2018/00357 ,  A61B2018/00577 ,  A61B2018/00839 ,  A61B2018/1407 ,  A61B2018/1475 ,  A61B2218/002 ,  A61B2218/005 ,  A61B2562/0209 ,  A61B2562/043 ,  A61B90/39

摘要： A recording and ablation catheter method and system for creating linear lesions in an atrial or other chamber of a heart is disclosed which includes an array of readily controlled electroded arcuate distal working catheter shapes that are easily deployed to contact the inner wall surface of the right atrial cardiac chamber in a manner that enables easy recording and mapping of impulses and thereafter facilitates sustained contact so that linear lesions can be produced from an array of mapping and ablation electrode devices serially spaced along the working catheter shape.

摘要翻译： 公开了一种记录和消融导管方法和系统，用于在心房或心房的其他腔室中产生线性损伤，其包括容易控制的电弧弓形远端工作导管形状的阵列，其易于部署以接触右心房的内壁表面 心室以能够容易地记录和映射脉冲的方式，然后促进持续接触，使得可以从沿着工作导管形状串联间隔的映射和消融电极装置的阵列产生线性损伤。

公开(公告)号：US5735847A

公开(公告)日：1998-04-07

申请号：US576435

申请日：1995-12-19

申请人： Edward J. Gough ,  Alan A. Stein

发明人： Edward J. Gough ,  Alan A. Stein

IPC分类号： A61B17/22 ,  A61B17/00 ,  A61B17/34 ,  A61B18/00 ,  A61B18/04 ,  A61B18/12 ,  A61B18/14 ,  A61B18/16 ,  A61B18/18 ,  A61M3/02 ,  A61M25/00 ,  A61N1/06 ,  A61N1/40 ,  A61N5/04 ,  A61B17/39

CPC分类号： A61B18/1477 ,  A61B18/1482 ,  A61B18/18 ,  A61B18/1815 ,  A61N1/06 ,  A61N1/403 ,  A61B18/1206 ,  A61B18/14 ,  A61B18/1402 ,  A61B18/1485 ,  A61B18/1492 ,  A61B2017/00022 ,  A61B2017/00101 ,  A61B2018/00011 ,  A61B2018/00023 ,  A61B2018/00196 ,  A61B2018/00273 ,  A61B2018/00452 ,  A61B2018/00476 ,  A61B2018/00577 ,  A61B2018/00666 ,  A61B2018/00678 ,  A61B2018/00702 ,  A61B2018/00708 ,  A61B2018/00726 ,  A61B2018/00744 ,  A61B2018/00761 ,  A61B2018/00779 ,  A61B2018/00791 ,  A61B2018/00797 ,  A61B2018/00827 ,  A61B2018/00875 ,  A61B2018/00892 ,  A61B2018/124 ,  A61B2018/1253 ,  A61B2018/126 ,  A61B2018/1425 ,  A61B2018/143 ,  A61B2018/1432 ,  A61B2018/1435 ,  A61B2018/1472 ,  A61B2018/162 ,  A61B2218/002 ,  A61M25/007 ,  A61M3/0279 ,  A61N5/04

摘要： An ablation apparatus includes a multiple antenna device coupled to an electromagnetic energy source that produces an electromagnetic energy ablation output. The multiple antenna device includes a primary antenna with a lumen and a longitudinal axis, and a secondary antenna deployable from the lumen in a lateral direction relative to the longitudinal axis. At least a distal end of each secondary antenna is structurally less rigid than the primary antenna, and the primary antenna is sufficiently rigid to be introduced through tissue. At least one cable coupling the multiple antenna device to the energy source. A cooling element is coupled to the primary antenna. A variety of energy sources can be used including RF, microwave and laser.

摘要翻译： 消融装置包括耦合到产生电磁能消融输出的电磁能源的多天线装置。 多天线装置包括具有内腔和纵向轴线的主天线，以及可相对于纵向轴线从横向方向从内腔展开的次级天线。 每个次级天线的至少远端在结构上比主天线刚性差，并且主天线足够刚性以通过组织引入。 将多个天线装置耦合到能量源的至少一个电缆。 冷却元件连接到主天线。 可以使用各种能源，包括射频，微波和激光。

公开(公告)号：US5683384A

公开(公告)日：1997-11-04

申请号：US515379

申请日：1995-08-15

申请人： Edward J. Gough ,  Alan A. Stein ,  Stuart D. Edwards

发明人： Edward J. Gough ,  Alan A. Stein ,  Stuart D. Edwards

IPC分类号： A61B17/22 ,  A61B17/00 ,  A61B17/34 ,  A61B18/00 ,  A61B18/04 ,  A61B18/12 ,  A61B18/14 ,  A61B18/16 ,  A61B18/18 ,  A61M3/02 ,  A61M25/00 ,  A61N1/06 ,  A61N1/40 ,  A61N5/04 ,  A61B17/39

CPC分类号： A61N1/403 ,  A61B18/1477 ,  A61B18/1482 ,  A61B18/18 ,  A61B18/1815 ,  A61N1/06 ,  A61B18/1206 ,  A61B18/14 ,  A61B18/1402 ,  A61B18/1485 ,  A61B18/1492 ,  A61B2017/00022 ,  A61B2017/00101 ,  A61B2018/00011 ,  A61B2018/00023 ,  A61B2018/00196 ,  A61B2018/00273 ,  A61B2018/00452 ,  A61B2018/00476 ,  A61B2018/00577 ,  A61B2018/00666 ,  A61B2018/00678 ,  A61B2018/00702 ,  A61B2018/00708 ,  A61B2018/00726 ,  A61B2018/00744 ,  A61B2018/00761 ,  A61B2018/00779 ,  A61B2018/00791 ,  A61B2018/00797 ,  A61B2018/00827 ,  A61B2018/00875 ,  A61B2018/00892 ,  A61B2018/124 ,  A61B2018/1253 ,  A61B2018/126 ,  A61B2018/1425 ,  A61B2018/143 ,  A61B2018/1432 ,  A61B2018/1435 ,  A61B2018/1472 ,  A61B2018/162 ,  A61B2218/002 ,  A61M25/007 ,  A61M3/0279 ,  A61N5/04

摘要： An ablation apparatus has a multiple antenna device of adjustable length including an adjustable length primary antenna and an adjustable length secondary antenna. The primary antenna has a longitudinal axis, and the secondary antenna is deployed in a direction lateral to the longitudinal axis. The secondary antenna is constructed to be structurally less rigid than the primary antenna. The adjustable lengths of the primary and secondary antennas permits a desired geometric ablation of a selected tissue mass. An adjustable insulation sleeve is positioned on an exterior of one of the primary or secondary antennas. An energy source is connected to the multiple antenna device. A variety of energy sources can be used including RF, microwave and laser.

摘要翻译： 消融装置具有可调长度的多天线装置，包括可调长度的主天线和可调长度的辅助天线。 主天线具有纵向轴线，并且辅助天线在纵向轴线的横向方向上展开。 次级天线被构造成在结构上比主天线刚性更低。 初级和次级天线的可调节长度允许所选择的组织块的期望的几何消融。 一个可调整的绝缘套管位于主天线或辅助天线之一的外部。 能量源连接到多天线装置。 可以使用各种能源，包括射频，微波和激光。

公开(公告)号：US5672174A

公开(公告)日：1997-09-30

申请号：US585532

申请日：1996-01-16

申请人： Edward J. Gough ,  Alan A. Stein

发明人： Edward J. Gough ,  Alan A. Stein

IPC分类号： A61B17/22 ,  A61B17/00 ,  A61B17/34 ,  A61B18/00 ,  A61B18/04 ,  A61B18/12 ,  A61B18/14 ,  A61B18/16 ,  A61B18/18 ,  A61M3/02 ,  A61M25/00 ,  A61N1/06 ,  A61N1/40 ,  A61N5/04 ,  A61B17/39

CPC分类号： A61B18/1477 ,  A61B18/1482 ,  A61B18/18 ,  A61B18/1815 ,  A61N1/06 ,  A61N1/403 ,  A61B18/1206 ,  A61B18/14 ,  A61B18/1402 ,  A61B18/1485 ,  A61B18/1492 ,  A61B2017/00022 ,  A61B2017/00101 ,  A61B2018/00011 ,  A61B2018/00023 ,  A61B2018/00196 ,  A61B2018/00273 ,  A61B2018/00452 ,  A61B2018/00476 ,  A61B2018/00577 ,  A61B2018/00666 ,  A61B2018/00678 ,  A61B2018/00702 ,  A61B2018/00708 ,  A61B2018/00726 ,  A61B2018/00744 ,  A61B2018/00761 ,  A61B2018/00779 ,  A61B2018/00791 ,  A61B2018/00797 ,  A61B2018/00827 ,  A61B2018/00875 ,  A61B2018/00892 ,  A61B2018/124 ,  A61B2018/1253 ,  A61B2018/126 ,  A61B2018/1425 ,  A61B2018/143 ,  A61B2018/1432 ,  A61B2018/1435 ,  A61B2018/1472 ,  A61B2018/162 ,  A61B2218/002 ,  A61M25/007 ,  A61M3/0279 ,  A61N5/04

摘要： An ablation treatment apparatus has a multiple antenna device. The multiple antenna device includes a primary antenna with a lumen, a longitudinal axis and an ablative surface area of length L.sub.1. The multiple antenna device also includes a secondary antenna that is positioned in the primary antenna as the primary antenna is introduced through tissue. A secondary antenna distal end is deployed at a selected tissue site from the primary antenna lumen in a lateral direction relative to the longitudinal axis. A sensor is at least partially positioned at an exterior of the secondary antenna distal end at a distance L.sub.2 from the primary antenna along the secondary antenna distal end. L.sub.2 is at least equal to 1/3 L.sub.1. An energy source is coupled to the primary antenna.

摘要翻译： 消融治疗装置具有多天线装置。 多天线装置包括具有内腔，纵向轴线和长度为L1的烧蚀表面积的主天线。 多天线装置还包括当通过组织引入主天线时位于主天线中的辅助天线。 次级天线远端相对于纵向轴线在横向方向上从主天线腔部署在选定的组织部位。 传感器至少部分地定位在辅助天线远端的外部，距离主天线沿辅助天线远端距离L2。 L2至少等于+ E，fra 1/3 + EE L1。 能量源耦合到主天线。

公开(公告)号：US5588432A

公开(公告)日：1996-12-31

申请号：US500115

申请日：1995-07-10

申请人： Robert J. Crowley

发明人： Robert J. Crowley

IPC分类号： A61B5/0456 ,  A61B8/12 ,  A61B10/00 ,  A61B10/02 ,  A61B17/00 ,  A61B17/22 ,  A61B17/34 ,  A61B18/14 ,  A61B19/00 ,  A61M29/02

CPC分类号： A61B5/6848 ,  A61B18/1492 ,  A61B5/02007 ,  A61B8/12 ,  A61B8/445 ,  A61B8/4461 ,  A61B8/463 ,  A61B10/0291 ,  A61B17/2202 ,  A61B17/34 ,  A61B2017/00243 ,  A61B2017/00924 ,  A61B2017/22051 ,  A61B2017/22077 ,  A61B2017/22078 ,  A61B2017/22082 ,  A61B2017/22084 ,  A61B2018/00029 ,  A61B2018/00077 ,  A61B2018/00107 ,  A61B2018/00148 ,  A61B2018/00208 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00273 ,  A61B2018/00351 ,  A61B2018/00577 ,  A61B2018/00797 ,  A61B2018/00898 ,  A61B2018/1425 ,  A61B2018/1435 ,  A61B2018/1861 ,  A61B2034/2063 ,  A61B2090/065 ,  A61B2090/378 ,  A61B2090/3782 ,  A61B5/0456 ,  A61B6/503 ,  A61B6/504 ,  A61B8/0883 ,  A61B8/0891 ,  A61B8/543 ,  A61B90/39 ,  A61M25/104

摘要： An acoustic imaging system for use within a heart has a catheter, an ultrasound device incorporated into the catheter, and an electrode mounted on the catheter. The ultrasound device directs ultrasonic signals toward an internal structure in the heart to create an ultrasonic image, and the electrode is arranged for electrical contact with the internal structure. A chemical ablation device mounted on the catheter ablates at least a portion of the internal structure by delivery of fluid to the internal structure. The ablation device includes a material that vibrates in response to electrical excitation, the ablation being at least assisted by vibration of the material. The ablation device may alternatively be a transducer incorporated into the catheter, arranged to convert electrical signals into radiation and to direct the radiation toward the internal structure. The electrode may be a sonolucent structure incorporated into the catheter, through which the ultrasound device is arranged to direct signals. An acoustic marker mounted on the catheter emits a sonic wave when electrically excited. A central processing unit creates a graphical representation of the internal structure, and super-imposes items of data onto the graphical representation at locations that represent the respective plurality of locations within the internal structure corresponding to the plurality of items of data. A display system displays the graphical representation onto which the plurality of items of data are super-imposed.

摘要翻译： 在心脏内使用的声学成像系统具有导管，并入导管中的超声装置和安装在导管上的电极。 超声波装置将超声波信号引导到心脏内的内部结构以产生超声波图像，并且电极被布置成与内部结构电接触。 安装在导管上的化学消融装置通过将流体输送到内部结构来消融内部结构的至少一部分。 消融装置包括响应于电激发而振动的材料，该消融至少由材料的振动辅助。 消融装置可替代地是并入到导管中的换能器，被布置成将电信号转换成辐射并将辐射引向内部结构。 电极可以是结合到导管中的声光结构，超声装置通过该电极布置成引导信号。 安装在导管上的声学标记在电激励时发出声波。 中央处理单元创建内部结构的图形表示，并且在表示对应于多个数据项的内部结构内的相应多个位置的位置处将数据项超额施加到图形表示上。 显示系统显示多个数据项被超强加在的图形表示。

公开(公告)号：US5423807A

公开(公告)日：1995-06-13

申请号：US186263

申请日：1994-01-24

申请人： Fredric L. Milder

发明人： Fredric L. Milder

IPC分类号： A61B18/12 ,  A61B5/0402 ,  A61B17/00 ,  A61B18/00 ,  A61B18/02 ,  A61B18/14 ,  A61B18/20 ,  A61B18/24 ,  A61B18/28 ,  A61F7/00 ,  A61M25/01 ,  A61B17/36

CPC分类号： A61M25/0158 ,  A61B18/02 ,  A61B18/1492 ,  A61B18/14 ,  A61B18/20 ,  A61B18/24 ,  A61B18/28 ,  A61B2017/00017 ,  A61B2017/00022 ,  A61B2017/00243 ,  A61B2017/00292 ,  A61B2017/003 ,  A61B2018/00011 ,  A61B2018/00023 ,  A61B2018/00077 ,  A61B2018/00095 ,  A61B2018/00273 ,  A61B2018/00357 ,  A61B2018/00577 ,  A61B2018/00815 ,  A61B2018/00821 ,  A61B2018/00839 ,  A61B2018/0212 ,  A61B2018/0275 ,  A61B2018/0281 ,  A61B2018/1253 ,  A61B2218/002 ,  A61B2218/003 ,  A61F2007/0056

摘要： The invention provides a catheter for ice mapping and ablation and a method of ablation using the catheter. The catheter includes at least two conduits for circulating a refrigerating fluid adjacent an ablation device located at the end of a catheter. The refrigerated ablation device is used to chill a localized region of myocardial tissue, thereby permitting the resulting change in electrical activity to be determined. In response to the test results, the ablation device may be used to make a lesion in the myocardial tissue to correct a cardiac arrhythmia. In one embodiment, the ablation device is an electrode which uses radio frequency energy to ablate the myocardial tissue. Alternatively, the ablation device is an electrode adapted for direct current ablation. In another embodiment, the electrode is replaced with an optical fiber in communication with a laser which uses the laser's light energy to ablate tissue. Yet another embodiment is a cryogenic catheter having combined or separate mapping and ablation devices. In another embodiment, a cryogenic catheter is provided having an inner conduit with a stepped down diameter. The embodiments may include provisions for steering the catheter and for stabilizing the ablation device at the proposed lesion site.

摘要翻译： 本发明提供一种用于冰图和消融的导管以及使用该导管消融的方法。 导管包括至少两个导管，用于使位于导管端部的消融装置附近的冷冻流体循环。 冷冻消融装置用于冷冻心肌组织的局部区域，从而允许确定所导致的电活动变化。 响应于测试结果，消融装置可用于在心肌组织中形成损伤以矫正心律失常。 在一个实施例中，消融装置是使用射频能量来消融心肌组织的电极。 或者，消融装置是适于直流消融的电极。 在另一个实施例中，电极被替换为与使用激光的光能来消融组织的激光器连通的光纤。 另一个实施例是具有组合或分离的映射和消融装置的低温导管。 在另一个实施例中，提供了具有具有阶梯下降直径的内导管的低温导管。 实施例可以包括用于转向导管并用于在所提出的病变部位处稳定消融装置的装置。