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81.发明申请Method and Apparatus for Delivering a Therapeutic Substance Through an Injection Port 审中-公开通过注射口输送治疗物质的方法和装置公开(公告)号：US20160015906A1
公开(公告)日：2016-01-21
申请号：US14868361
申请日：2015-09-28
CPC分类号： A61M5/3202 , A61J1/1406 , A61J1/201 , A61J1/2048 , A61J1/2055 , A61J1/2065 , A61J1/2096 , A61M5/001 , A61M5/158 , A61M5/3134 , A61M5/3287 , A61M39/0208 , A61M39/0247 , A61M2005/1587 , A61M2039/027 , A61M2039/0276 , A61M2039/0285 , A61M2039/0288 , A61M2039/0294
摘要： Adapters for utilizing a syringe or pen injector with a subcutaneous injection port to deliver a therapeutic substance through the injection port and methods of using the adapters are provided. A syringe adapter has a body having a first end and a second end. The first end of the body is configured to receive and engage the end of a syringe so that the cannula of the syringe is held at a fixed position with the respect to the adapter. The second end of the adapter configured to mate with a mating portion of the injection port. When the second end of the adapter engages the mating portion of the injection port, the adapter assures that the cannula of the syringe is properly aligned with the subcutaneous injection port and assures that the cannula penetrates the injection port to the proper depth. Adapters for use with pen style delivery systems are also disclosed. Additionally, an adapter to facilitate loading a syringe with a therapeutic substance from a vial is disclosed.
摘要翻译： 提供了用于使用具有皮下注射口的注射器或笔式注射器通过注射口输送治疗物质的适配器和使用适配器的方法。 注射器适配器具有具有第一端和第二端的主体。 本体的第一端构造成接收和接合注射器的端部，使得注射器的套管相对于适配器保持在固定位置。 适配器的第二端被配置为与注入端口的配合部分配合。 当适配器的第二端接合注射口的配合部分时，适配器确保注射器的插管与皮下注射口适当地对齐并且确保套管穿过注射端口到合适的深度。 还公开了用于笔式传送系统的适配器。 此外，公开了一种用于便于从小瓶装载具有治疗物质的注射器的适配器。
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82.发明授权Molecular imaging vial transport container and fluid injection system interface 有权分子成像小瓶运输容器和流体注射系统界面公开(公告)号：US09233776B2
公开(公告)日：2016-01-12
申请号：US13800194
申请日：2013-03-13
申请人： MEDRAD, INC.
发明人： Jason L Bazala , Ryan C Kaintz
CPC分类号： A61J1/2065 , A61J1/1412 , A61J1/16 , A61J1/20 , A61J1/201 , A61J1/2096 , A61M5/007 , A61N5/1002 , A61N2005/1021 , A61N2005/1094
摘要： A pharmaceutical transport container includes a first body portion adapted to receive at least a portion of a pharmaceutical vial, a second body portion removably engaged with the first body portion to fully enclose the vial, and a flexible ring positioned in an interior cavity of the second body portion and configured to flex between a relaxed state and a radially-outward extended state. The pharmaceutical transport container may also include a removable end cap having a receiving chamber to receive the first body portion, and/or a guide tab extending from an exterior surface of the second body portion to engage a guide slot defined in a fluid injection system docking station, whereby the transport container translates axially and rotationally into the docking station to establish a fluid connection between the vial and a fluid connector mechanism or element disposed within the docking station.
摘要翻译： 药物运输容器包括适于容纳药物瓶的至少一部分的第一主体部分，可移除地与第一主体部分接合以完全包围小瓶的第二主体部分，以及定位在第二主体部分的内部空腔中的柔性环 主体部分并且构造成在松弛状态和径向向外延伸状态之间弯曲。 药物运输容器还可以包括具有容纳第一主体部分的容纳室的可拆卸端盖和/或从第二主体部分的外表面延伸的引导片，以与限定在流体注射系统对接件 站，由此运输容器轴向地和旋转地平移到对接站中，以在小瓶和布置在对接站内的流体连接器机构或元件之间建立流体连接。
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公开(公告)号：US09220661B2
公开(公告)日：2015-12-29
申请号：US14543939
申请日：2014-11-18
发明人： Jared Garfield , John Slump , Gregory Lyon
CPC分类号： A61J1/22 , A61J1/1406 , A61J1/201 , A61J1/2017 , A61J1/2048 , A61J1/2051 , A61J1/2055 , A61J1/2062 , A61J1/2072 , A61J1/2096 , B65B3/003
摘要： A medicament transport system includes a syringe adapter assembly; and a vial adapter assembly including a base defining an opening having a seal member disposed therewithin, a stem extending from the base and defining a lumen therethrough and an opening through a wall thereof, a needle shuttle valve slidably disposed within the lumen of the stem and supporting a transfer needle and a vacuum needle; and a vacuum cup slidably supported on the stem, wherein a vacuum chamber is defined in the space between the base, the stem and the vacuum cup. The medicament transport system includes a condition where the transfer needle and the vacuum needles penetrate the seal member of the vial adapter assembly, and the vacuum cup is moved to draw a vacuum through the vacuum needle. An automation system is provided that utilizes a medicament transport system for forming a medicament solution from a liquid/non-liquid solution.
摘要翻译： 一种药物输送系统，包括注射器适配器组件; 以及小瓶适配器组件，其包括限定具有设置在其中的密封构件的开口的基部，从所述基部延伸并限定穿过其中的腔的杆和穿过其壁的开口;可滑动地设置在所述茎的内腔内的针梭阀， 支撑转移针和真空针; 以及可滑动地支撑在所述杆上的真空杯，其中在所述基座，所述杆和所述真空杯之间的空间中限定真空室。 药物输送系统包括转移针和真空针穿透小瓶适配器组件的密封构件的状态，真空杯移动以通过真空针抽真空。 提供了一种自动化系统，其利用用于从液体/非液体溶液形成药物溶液的药物输送系统。
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公开(公告)号：US09205248B2
公开(公告)日：2015-12-08
申请号：US12711641
申请日：2010-02-24
申请人： Yongxian Wu , Yun Jin , Mitali Aon , Michael D. Garrison
发明人： Yongxian Wu , Yun Jin , Mitali Aon , Michael D. Garrison
CPC分类号： A61M39/24 , A61J1/201 , A61J1/2037 , A61J1/2051 , A61J1/2096 , A61M39/26 , A61M2039/248 , A61M2039/261
摘要： Drug delivery connectors are provided for permitting and blocking fluid flow between a container and a catheter connector or other drug delivery site. Embodiments of the drug delivery connectors include a ball valve for forming a releasable seal within the drug delivery connectors. In one or more embodiments, the ball valve prevents fluid flow between an open proximal end and an open distal end of the drug delivery connector and is movable in a proximal direction to release the releasable seal to permit fluid flow from the open proximal direction to the open distal direction. Methods of delivering medication to a catheter connector that includes an actuator are also provided.
摘要翻译： 药物递送连接器用于允许和阻止容器和导管连接器或其它药物递送部位之间的流体流动。 药物递送连接器的实施例包括用于在药物输送连接器内形成可释放密封的球阀。 在一个或多个实施例中，球阀防止流体在药物输送连接器的开放的近端和敞开的远端之间流动，并且可以在近端方向上移动以释放可释放的密封，以允许流体从开口的近端方向流到 开放远端方向。 还提供了将药物递送到包括致动器的导管连接器的方法。
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公开(公告)号：US09205191B2
公开(公告)日：2015-12-08
申请号：US13961798
申请日：2013-08-07
发明人： Julian D. Kavazov
CPC分类号： A61J1/2089 , A61J1/16 , A61J1/20 , A61J1/2006 , A61J1/201 , A61J1/2013 , A61J1/2048 , A61J1/2051 , A61J1/2065 , A61J1/2068 , A61J1/2072 , A61J1/2075 , A61M5/1413 , A61M5/14244 , A61M5/14248 , A61M5/162 , A61M5/165 , A61M5/36 , A61M2005/14268 , A61M2005/341 , A61M2207/00 , A61M2209/045 , B65B3/003
摘要： Various embodiments of the present invention are directed to transferring fluidic media from a vial to a reservoir. In various embodiments, fluidic media may be transferred from the vial to the reservoir by moving a housing portion to move a plunger head located in the reservoir to draw fluidic media from the vial to the reservoir. In other embodiments, fluidic media may be transferred from the vial to the reservoir while the reservoir is held by a holding unit and vibrated by a vibrator to remove air from the fluidic media. In some embodiments, fluidic media may be transferred from the vial to the reservoir by moving a handle operatively connected to a bias member for assisting with the transfer of fluidic media. In other embodiments, the transfer of fluidic media may be assisted by a bias member and a needle connecting atmosphere and the vial.
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公开(公告)号：US09186493B2
公开(公告)日：2015-11-17
申请号：US14476900
申请日：2014-09-04
发明人： Rudolf Pavlik
CPC分类号： A61J1/2051 , A61J1/201 , A61J1/2048 , A61M39/10 , A61M39/1055 , A61M39/12 , A61M39/16 , A61M39/18 , A61M2039/1072 , A61M2039/2433 , A61M2039/2473 , B65B3/003
摘要： An aseptic connector assembly and a method of aseptically transferring fluid are provided. The aseptic connector assembly includes a body portion, the body portion having a receptacle configured to receive a corresponding fill connector; a pivot portion adjustably disposed within and extending partially from the body portion, the pivot portion having a channel formed therein; and a conduit portion axially slidably disposed within the channel formed in the pivot portion. The pivot portion comprises a ready position and an operative position, the pivot portion being adjustable from the ready position to the operative position via relative movement with respect to the body portion. The method includes providing an aseptic connector in a ready position, coupling a flexible tubing and a fill connector to the aseptic connector, moving a pivot portion to an operative position, axially sliding the conduit portion into the fill connector, and transferring a fluid through the connector.
摘要翻译： 提供无菌连接器组件和无菌转移流体的方法。 所述无菌连接器组件包括主体部分，所述主体部分具有被配置为容纳相应的填充连接器的插座; 枢转部分可调节地设置在主体部分内并部分地从主体部分延伸，枢转部分具有形成在其中的通道; 以及导管部分，其轴向可滑动地设置在形成在枢转部分中的通道内。 枢转部分包括准备位置和操作位置，枢转部分可以通过相对于主体部分的相对运动从就绪位置调整到操作位置。 该方法包括将无菌连接器提供在就绪位置，将柔性管和填充连接器连接到无菌连接器，将枢轴部分移动到操作位置，将导管部分轴向滑动到填充连接器中，以及将流体通过 连接器。
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公开(公告)号：US20150320640A1
公开(公告)日：2015-11-12
申请号：US14409127
申请日：2013-07-02
CPC分类号： A61J1/2048 , A61J1/201 , A61J1/2089 , A61J1/2096 , A61M5/002 , A61M2207/00 , B65B3/003 , B65B55/027 , F04C2270/0421 , Y10T29/49828
摘要： The invention relates to a method of manufacturing a medical device (1, 299, 399), the method comprising: (i) receiving in a first cleanroom environment categorised by a first airborne particulate cleanliness a plurality of medical components (10, 20, 50, 50′, 210, 220, 320, 350) prepared in a second cleanroom environment categorised by a second airborne particulate cleanliness, which is higher than the first airborne particulate cleanliness, where each of the plurality of medical components (10, 20, 50, 50′, 210, 220, 320, 350) comprises a sealed surface portion, (ii) assembling at least the plurality of medical components (10, 20, 50, 50′, 210, 220, 320, 350) in the first cleanroom environment, thereby providing a sub-assembly, and (iii) establishing an enclosure for the sub-assembly capable of maintaining an internal airborne particulate cleanliness equivalent to the first airborne particulate cleanliness.
摘要翻译： 本发明涉及一种制造医疗装置的方法，该方法包括：（i）在由第一空气中的颗粒清洁度分类的第一洁净室环境中接收多个医疗部件（10,20,50） ，50'，210,220,320,350），其被制备在由第二空气中的颗粒清洁度分类的第二洁净室环境中，所述第二空气中的颗粒清洁度高于第一空气中的颗粒清洁度，其中多个医疗部件（10,20,50 ，50'，210,220,320,350）包括密封表面部分，（ii）将至少所述多个医疗部件（10,20,50,50'，210,220,320,350）组装在所述第一 洁净室环境，从而提供子组件，以及（iii）建立能够保持与第一空气中的颗粒清洁度相当的内部空气中的颗粒清洁度的子组件的外壳。
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公开(公告)号：US09180070B2
公开(公告)日：2015-11-10
申请号：US14375173
申请日：2013-02-01
发明人： Franck Carrel , Lionel Maritan , Frederic Perot
CPC分类号： A61J1/2096 , A61J1/1406 , A61J1/201 , A61J1/2058 , Y10T137/9029
摘要： An adaptor for coupling with a medical container having a collar closed by a septum including: a tubular body closed at a distal end with a transversal wall from which extends a hollow spike, and at a proximal end by a pierceable elastomeric piece including a cavity having a plurality of circumferentially distributed chambers, each chamber being connected to the hollow spike by a radial channel, the tubular body further receiving an intermediate piece including a plurality of through holes aligned on the chambers, a selecting member having a closure wall provided with one opening, capable of rotating so that the opening is successively aligned with each of the through holes, and a gripping member for securing the adaptor to the medical container. Also, an assembly including the adaptor and a medical container.
摘要翻译： 一种用于与医疗容器联接的适配器，其具有由隔膜封闭的套环，包括：在远端处封闭的管状体，横向壁从所述横向壁延伸，并且在近端由可刺破的弹性体件包括空腔， 多个周向分布的室，每个室通过径向通道连接到所述中空尖峰，所述管体还包括中间件，所述中间件包括在所述室上对准的多个通孔，选择构件具有封闭壁，所述封闭壁设置有一个开口 能够旋转使得开口与每个通孔连续对准，以及用于将适配器固定到医疗容器的夹持构件。 而且，包括适配器和医疗容器的组件。
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89.发明申请System for Closed Transfer of Fluids and Membrane Arrangements for Use Thereof 审中-公开用于封闭传输流体和膜排布的系统公开(公告)号：US20150297839A1
公开(公告)日：2015-10-22
申请号：US14691922
申请日：2015-04-21
IPC分类号： A61M5/34
CPC分类号： A61M5/34 , A61J1/1406 , A61J1/201 , A61J1/2055 , A61J1/2065 , A61J1/2096 , A61M2005/3103
摘要： A syringe adapter includes a housing having a first end and a second end with the first end configured to be secured to a first container, a cannula having a first end and a second end with the second end of the cannula positioned within the housing, and a collet having a first end and a second end. At least a portion of the collet is received within the housing. The collet includes a body defining a passageway, a membrane received by the passageway, and a locking member connected to the body of the collet. The membrane has a body with a first end and a second end. The body of the membrane defines a passageway. The collet is movable from a first position where the locking member is open to receive a mating connector to a second position where radially outward movement of the locking member is restricted.
摘要翻译： 注射器适配器包括具有第一端和第二端的壳体，第一端被构造成固定到第一容器，套管具有第一端和第二端，套管的第二端定位在壳体内，以及 具有第一端和第二端的夹头。 夹头的至少一部分被容纳在壳体内。 夹头包括限定通道的主体，由通道接收的膜和连接到夹头主体的锁定构件。 膜具有具有第一端和第二端的主体。 膜的主体限定通道。 夹头可以从锁定构件打开的第一位置移动，以将配合连接器接收到限制锁定构件的径向向外运动的第二位置。
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公开(公告)号：US20150297461A1
公开(公告)日：2015-10-22
申请号：US14789806
申请日：2015-07-01
申请人： ICU Medical, Inc.
发明人： Thomas F. Fangrow
CPC分类号： A61J1/2096 , A61J1/10 , A61J1/201 , A61J1/2048 , A61J1/2075 , A61J1/2082 , A61J1/2086 , B65B3/003 , Y10T29/49826
摘要： In certain embodiments, a vial adaptor comprises a housing configured to couple the adaptor with a vial, an access channel, a regulator channel, and a regulator assembly. The access channel is configured to facilitate withdrawal of fluid from the vial when the adaptor is coupled to the vial. The regulator channel is configured to facilitate a flow of a regulating fluid from the regulator assembly to compensate for changes in volume of a medical fluid in the vial. In some embodiments, the regulator assembly includes a flexible member configured to expand and contract in accordance with changes in the volume of the medical fluid in the vial. In some embodiments, the flexible member is substantially free to expand and contract. In some embodiments, the flexible member is not partly or completely located in a rigid enclosure.
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