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    Cartridges and Instruments for Sample Analysis
    3.
    发明申请
    Cartridges and Instruments for Sample Analysis 有权

    公开(公告)号：US20210278427A1

    公开(公告)日：2021-09-09

    申请号：US17211212

    申请日：2021-03-24

    申请人： INTEGENX INC.

    发明人： James Ogg ,  David Eberhart ,  William D. Nielsen ,  Helen Franklin ,  Stevan B. Jovanovich

    IPC分类号： G01N35/00 ,  B01L3/00 ,  B01L7/00 ,  C12Q1/6818 ,  C12Q1/686 ,  C12Q1/6888

    摘要： Provided herein are instruments and cartridges for processing samples. The cartridges include fluidic circuits in which fluid movement can be regulated by diaphragm valves. In certain cartridges, deformable material providing a diaphragm contacts an interface in the instrument that actuates the diaphragm directly, without intervening actuation layer. Certain cartridges have a plurality of fluidic circuits and fluid distribution channels or pneumatic distribution channels configured to deliver fluids or pneumatic pressure to any of the fluidic circuits, selectively. Certain cartridges have compartments containing on-board reagents. Compartments can be closed by a film attached to a body the cartridge through a heat seal.

    Cartridges and instruments for sample analysis
    4.
    发明授权
    Cartridges and instruments for sample analysis 有权

    公开(公告)号：US10989723B2

    公开(公告)日：2021-04-27

    申请号：US16258412

    申请日：2019-01-25

    申请人： IntegenX Inc.

    发明人： James Ogg ,  David Eberhart ,  William D. Nielsen ,  Helen Franklin ,  Stevan B. Jovanovich

    IPC分类号： B01L3/00 ,  G01N35/00 ,  B01L7/00 ,  C12Q1/6818 ,  C12Q1/686 ,  C12Q1/6888

    摘要： Provided herein are instruments and cartridges for processing samples. The cartridges include fluidic circuits in which fluid movement can be regulated by diaphragm valves. In certain cartridges, deformable material providing a diaphragm contacts an interface in the instrument that actuates the diaphragm directly, without intervening actuation layer. Certain cartridges have a plurality of fluidic circuits and fluid distribution channels or pneumatic distribution channels configured to deliver fluids or pneumatic pressure to any of the fluidic circuits, selectively. Certain cartridges have compartments containing on-board reagents. Compartments can be closed by a film attached to a body the cartridge through a heat seal.

    Systems and methods for live help
    6.
    发明授权
    Systems and methods for live help 有权

    公开(公告)号：US10725801B2

    公开(公告)日：2020-07-28

    申请号：US15761066

    申请日：2016-09-21

    申请人： IntegenX Inc.

    发明人： David King ,  Chungsoo Charles Park

    IPC分类号： G06F3/0481 ,  G06F9/451 ,  G06F3/0487 ,  G06Q30/00

    摘要： A live help system provides an intuitive display of help information on a user's graphical user interface. A request is received from a client device for help, and a live help provider interface is initiated at a live help location. Data is acquired regarding a user's location, including data on external devices in the user's location. Indicators are provided to allow the live help provider to point to or otherwise indicate items on the user interface or outside of the user interface. Live help input is captured at the live help provider interface. Instructions are then transmitted to the display of the client device to display live help input, as though the agent were present and interacting with or indicating items on the screen or off the screen.

    Microfluidic methods
    7.
    发明授权
    Microfluidic methods 有权
    微流控方法

    公开(公告)号：US08672532B2

    公开(公告)日：2014-03-18

    申请号：US12642665

    申请日：2009-12-18

    申请人： Stevan B. Jovanovich ,  William D. Nielsen ,  Michael Van Nguyen

    发明人： Stevan B. Jovanovich ,  William D. Nielsen ,  Michael Van Nguyen

    IPC分类号： B01F5/06

    CPC分类号： B01F5/06 ,  B01F11/0045 ,  B01F13/0059 ,  F16K99/0001 ,  F16K99/0015 ,  F16K99/0036 ,  F16K99/0046 ,  F16K99/0059 ,  Y10T137/0318 ,  Y10T137/87153 ,  Y10T137/877

    摘要： This invention provides microfluidic devices that comprise a fluidics layer having microfluidic channels and one or more regulating layers that regulate the movement of fluid in the channels. The microfluidic devices can be used to mix one or more fluids. At least a portion of the fluidics layer can be isolated from the regulating layer, for example in the form of a shelf. Such isolated portions can be used as areas in which the temperature of liquids is controlled. Also provided are instruments including thermal control devices into which the microfluidic device is engaged so that the thermal control device controls temperature in the isolated portion, and a movable magnetic assembly including magnets with shields so that a focused magnetic field can be applied to or withdrawn from the isolated portion or any other portion of the microfluidic device. Also provided are methods of mixing fluids. The methods include stacking a plurality of alternating boluses of different liquids in a microfluidic channel, and moving the stacked boluses through the channel. In another method, the boluses are moved into a diaphragm valve having a volume able to accommodate several boluses, and then pumping the liquids out of the valve.

    摘要翻译： 本发明提供了微流体装置，其包括具有微流体通道的流体层和调节通道中的流体运动的一个或多个调节层。 微流体装置可以用于混合一种或多种流体。 流体层的至少一部分可以与调节层隔离，例如以搁板的形式。 这种隔离部分可以用作控制液体温度的区域。 还提供了包括热控制装置的仪器，其中微流体装置被接合到其中，使得热控制装置控制隔离部分中的温度，以及可移动磁性组件，其包括具有屏蔽的磁体，使得可以将聚焦磁场施加到或从 微流体装置的隔离部分或任何其它部分。 还提供了混合流体的方法。 这些方法包括在微流体通道中堆叠多个不同液体的交替喷射，并且通过通道移动堆叠的推注。 在另一种方法中，将大团块移动到具有能够容纳多次喷射的体积的隔膜阀中，然后将液体泵出阀。