公开(公告)号：US08955340B2

公开(公告)日：2015-02-17

申请号：US12685952

申请日：2010-01-12

申请人： Aaron Burke ,  Michael Felo ,  Brian Pereira ,  Elias Noukas ,  Dennis Wong

发明人： Aaron Burke ,  Michael Felo ,  Brian Pereira ,  Elias Noukas ,  Dennis Wong

IPC分类号： F25D25/00 ,  B65B63/08 ,  F25D3/08 ,  F25D29/00 ,  A01N1/02

CPC分类号： F25D29/00 ,  A01N1/0263 ,  F25D2331/802 ,  F25D2400/28 ,  F25D2400/30 ,  F25D2600/06 ,  F25D2700/12 ,  Y10T29/53

摘要： The biocontainer of the present invention provides a low cost, simple solution of many of the problems encountered during shipping, freezing and thawing of biopharmaceutical materials. The present invention enables a user to monitor the temperature profile of each biopharmaceutical container during the cryogenic process, so as to ensure the integrity of materials within each biocontainer by using a pre-installed and pre-sterilized temperature sensor. In some embodiments, the sensor assembly includes a wireless transmitter and is capable of transmitting information regarding the measured reading. In other embodiments, the sensor assembly includes a processing unit, which determines whether the temperature profile is acceptable. In a further embodiment, an indicator is included, such that the processing unit may indicate whether the biopharmaceutical material has been properly frozen. In other embodiments, the sensor assembly also includes a storage element, which is capable of storing various parameters during the freezing process.

摘要翻译： 本发明的生物容器提供了在生物药物材料的运输，冷冻和解冻期间遇到的许多问题的低成本，简单的解决方案。 本发明使得用户能够在低温过程期间监测每个生物药物容器的温度曲线，以便通过使用预先安装和预灭菌的温度传感器来确保每个生物容器内的材料的完整性。 在一些实施例中，传感器组件包括无线发射器，并且能够发送关于测量读数的信息。 在其他实施例中，传感器组件包括处理单元，其确定温度分布是否可接受。 在另一实施例中，包括指示器，使得处理单元可以指示生物药物材料是否已被适当地冷冻。 在其他实施例中，传感器组件还包括存储元件，其能够在冷冻过程期间存储各种参数。

公开(公告)号：US08497775B2

公开(公告)日：2013-07-30

申请号：US13301871

申请日：2011-11-22

申请人： Aaron Burke

发明人： Aaron Burke

IPC分类号： G08B13/14 ,  H01L21/00 ,  H01L29/82 ,  A61L2/00

CPC分类号： G11C11/22 ,  A61L2/081 ,  A61L2202/24 ,  B65B55/16 ,  G06K19/077 ,  G06K19/07749 ,  G11C11/16

摘要： A system and method for utilizing RFID tags in environments where radiation is used is disclosed. RFID tags are secured to various components of a pharmaceutical system, thereby enabling the customer to download pertinent information about the component, such as lot number, date of manufacturer, test parameters, etc. The tags can be applied to the component immediately after manufacture and can be subjected to the sterilization process without risk of data loss or corruption. The memory device within the tag utilizes a technology that does not rely upon charge storage as its mechanism to store information.

摘要翻译： 公开了在使用辐射的环境中利用RFID标签的系统和方法。 RFID标签被固定到药物系统的各种组件，从而使客户能够下载关于组件的相关信息，例如批号，制造商的日期，测试参数等。标签可以在制造后立即应用于部件， 可以进行灭菌过程，而不会有数据丢失或损坏的风险。 标签内的存储设备利用不依赖于电荷存储作为其存储信息的机制的技术。

公开(公告)号：US08405508B2

公开(公告)日：2013-03-26

申请号：US11501446

申请日：2006-08-09

申请人： Aaron Burke

发明人： Aaron Burke

IPC分类号： G08B13/14 ,  H01L21/00 ,  H01L29/82 ,  A61L2/00

CPC分类号： G11C11/22 ,  A61L2/081 ,  A61L2202/24 ,  B65B55/16 ,  G06K19/077 ,  G06K19/07749 ,  G11C11/16

摘要： A system and method for utilizing RFID tags in environments where radiation is used is disclosed. RFID tags are secured to various components of a pharmaceutical system, thereby enabling the customer to download pertinent information about the component, such as lot number, date of manufacturer, test parameters, etc. The tags can be applied to the component during or immediately after manufacture and can be subjected to the sterilization process without risk of data loss or corruption. The memory device within the tag utilizes a technology that does not rely upon charge storage as its mechanism to store information.

摘要翻译： 公开了在使用辐射的环境中利用RFID标签的系统和方法。 RFID标签被固定在药物系统的各种组件上，从而使客户能够下载关于组件的相关信息，例如批号，制造商日期，测试参数等。标签可以在或之后被应用于组件 制造并可以进行灭菌过程，而不会有数据丢失或损坏的风险。 标签内的存储设备利用不依赖于电荷存储作为其存储信息的机制的技术。

公开(公告)号：US07969380B2

公开(公告)日：2011-06-28

申请号：US13020914

申请日：2011-02-04

申请人： Aaron Burke ,  Michael Joens

发明人： Aaron Burke ,  Michael Joens

IPC分类号： H01Q1/42

CPC分类号： H01Q9/16 ,  B01D29/52 ,  B01D46/4245 ,  B01D46/429 ,  B01D2201/34 ,  B01D2201/56 ,  B01D2271/02 ,  H01Q1/22 ,  H01Q1/2216 ,  H01Q1/40 ,  H01Q1/50

摘要： A method and apparatus for providing wireless communication and optionally power to the interior of a housing assembly is disclosed. In one embodiment, an antenna is molded within a gasket material, such as silicon, so as to be completely encapsulated. The gasket preferably includes at least one support arm, which holds the antenna toward the middle of the housing, so as to minimize interference from the metal housing. In further embodiments, an inductive coil is encapsulated in the gasket. An alternating current is passed through this coil to create a changing magnetic field, which can then be used to create electrical power in physically separate components, such as filtering elements. In certain embodiments, multiple loops are molded to correspond to multiple filtering elements within the housing.

摘要翻译： 公开了一种用于向壳体组件的内部提供无线通信和可选地供电的方法和装置。 在一个实施例中，将天线模制在衬垫材料（例如硅）内，以便被完全封装。 垫片优选地包括至少一个支撑臂，其将天线朝向壳体的中间保持，以便最小化来自金属壳体的干扰。 在另外的实施例中，感应线圈封装在垫圈中。 交流电流通过该线圈以产生变化的磁场，其然后可用于在物理上分离的部件（例如过滤元件）中产生电力。 在某些实施例中，模制多个环以对应于壳体内的多个过滤元件。

公开(公告)号：US07892471B2

公开(公告)日：2011-02-22

申请号：US11985471

申请日：2007-11-15

申请人： Aaron Burke ,  Joseph William Muldoon

发明人： Aaron Burke ,  Joseph William Muldoon

IPC分类号： B29C65/02

CPC分类号： B29C66/474 ,  B29C65/02 ,  B29C65/06 ,  B29C65/08 ,  B29C65/14 ,  B29C66/112 ,  B29C66/1122 ,  B29C66/114 ,  B29C66/24244 ,  B29C66/30221 ,  B29C66/30223 ,  B29C66/47 ,  B29C66/472 ,  B29C66/53461 ,  B29C66/61 ,  B29C66/71 ,  B29C70/70 ,  B29C70/74 ,  G06K19/07758 ,  Y10T403/28 ,  Y10T428/1352 ,  B29K2023/00 ,  B29K2023/06 ,  B29K2023/083 ,  B29K2023/12 ,  B29K2027/06 ,  B29K2027/12 ,  B29K2027/16 ,  B29K2033/20 ,  B29K2055/02 ,  B29K2067/00 ,  B29K2069/00 ,  B29K2077/00 ,  B29K2081/06

摘要： The invention described herein provides an embedded wireless device such as a RFID tag molded into separate housing formed of any thermoplastic material compatible to that of the plastic material as the device to which the housing is to be attached. Subsequently, the housed tag assembly can be thermally bonded onto the device through many means which are well known and accepted in the industry.

摘要翻译： 本文描述的本发明提供了一种嵌入式无线设备，例如模制成分离的壳体的RFID标签，其由与塑料材料相兼容的任何热塑性材料形成，作为与壳体相连接的装置。 随后，容纳的标签组件可以通过工业上众所周知和被接受的许多方式热粘合到设备上。

公开(公告)号：US20100201521A1

公开(公告)日：2010-08-12

申请号：US12452747

申请日：2008-07-18

申请人： George Adams ,  John Dana Hubbard ,  Aaron Burke ,  Anthony DiLeo

发明人： George Adams ,  John Dana Hubbard ,  Aaron Burke ,  Anthony DiLeo

IPC分类号： G08B13/14

CPC分类号： G01N35/00732 ,  B01L3/505 ,  B01L3/545 ,  B01L2300/022 ,  C12M33/00 ,  C12M33/06 ,  C12M37/00 ,  G01N1/18 ,  G01N2001/1031 ,  G01N2001/205 ,  G01N2035/00782 ,  G01N2035/00801

摘要： The present invention uses a wireless memory/communication device at least on the one or more sample storage devices, preferably on both the one or more sample storage devices and the sampling holder, optionally the port on the equipment as well. Data such as that relating to the vessel, the location of the port on the vessel, the device, its manufacture date or lot number, the date of the installation, sterilization and/or taking of a sample along with the person who installed the device and/or took the sample can be read and preferably added to the wireless device when a read/write type of device as these events occur through a scanner/reader/writer device (fixed or hand held). The sample storage device in the laboratory can also then be read and recorded to track the sample storage device's life.

摘要翻译： 本发明至少在至少一个或多个样本存储设备上使用无线存储器/通信设备，优选地在一个或多个采样存储设备和采样保持器两者上，可选地，设备上的端口也使用无线存储器/通信设备。 与船舶有关的数据，船上港口的位置，设备，其制造日期或批号，安装日期，灭菌和/或采样样品以及安装设备的人员 当通过扫描仪/读写器装置（固定或手持）发生这些事件的读/写类型的装置时，可以读取样本并且优选地添加到无线装置。 实验室中的样品存储设备也可以被读取和记录，以跟踪样品存储设备的使用寿命。

公开(公告)号：US20100170833A1

公开(公告)日：2010-07-08

申请号：US12715496

申请日：2010-03-02

申请人： Michael T. Grzonka ,  Aaron Burke

发明人： Michael T. Grzonka ,  Aaron Burke

IPC分类号： B01D35/14 ,  B01D17/12 ,  H02J17/00

CPC分类号： B01D35/143 ,  B01D46/429 ,  B01D2201/52 ,  B01D2201/56 ,  B01D2201/58 ,  H02J5/005 ,  H02J7/025 ,  H02J50/10 ,  H02J50/70

摘要： The present invention describes a system and method for supplying electrical power to a device, such as a filter element, located within a housing. In one embodiment, a conductive coil is embedded into the housing base, and a second coil is embedded into the filter element. Current is then passed through the coil in the housing base. Through induction, a current is created in the second coil in the filter element, in much the same way as a transformer functions. This inductive field may interfere with the operation of the various electronic functions, such as communications, sensing or other activities. To overcome this issue, an energy storage component, such as a capacitor, is included in the filter electronics. In this way, the power generated by the inductive field can be stored, and used when the inductive field is no longer present.

摘要翻译： 本发明描述了一种用于向位于壳体内的诸如过滤元件的装置提供电力的系统和方法。 在一个实施例中，导电线圈被嵌入到壳体基座中，并且第二线圈被嵌入到过滤元件中。 电流然后通过壳体基座中的线圈。 通过感应，以与变压器功能大致相同的方式在滤波器元件中的第二线圈中产生电流。 该感应场可能会干扰诸如通信，感测或其他活动的各种电子功能的操作。 为了克服这个问题，诸如电容器的能量存储部件被包括在滤波器电子器件中。 以这种方式，可以存储由感应场产生的功率，并且当感应场不再存在时使用。

公开(公告)号：US08798954B2

公开(公告)日：2014-08-05

申请号：US13414886

申请日：2012-03-08

申请人： Aaron Burke

发明人： Aaron Burke

IPC分类号： A61L2/08

CPC分类号： A61L2/081 ,  A61L2/087 ,  A61L2202/24

摘要： A system and method for implementing embedded electronics in environments where radiation or extreme temperatures are used is disclosed. Embedded electronics are affixed to various components of a pharmaceutical system, thereby enabling the customer to download pertinent information about the component, such as lot number, date of manufacturer, test parameters, etc. Additionally, these electronics allow an array of functions and features to be implemented, such as integrity tests and diagnostics. The electronics in the pharmaceutical components utilize a technology that is not as susceptible to radiation and extreme temperatures as traditional electronics.

摘要翻译： 公开了一种在使用辐射或极端温度的环境中实现嵌入式电子设备的系统和方法。 嵌入式电子设备固定在药物系统的各种组件上，从而使客户能够下载有关组件的相关信息，例如批号，制造商日期，测试参数等。此外，这些电子装置允许一系列功能和特征 实施，如​​完整性测试和诊断。 药物部件中的电子元件利用了不像传统电子产品那样易受辐射和极端温度影响的技术。

公开(公告)号：US08501119B2

公开(公告)日：2013-08-06

申请号：US12079396

申请日：2008-03-26

申请人： Aaron Burke ,  Jiwan Adhikari

发明人： Aaron Burke ,  Jiwan Adhikari

IPC分类号： B01D35/00

CPC分类号： H01Q19/10 ,  G06K7/10178 ,  H01Q1/22 ,  H01Q1/40 ,  H01Q7/00

摘要： A method and apparatus for providing more reliable wireless communication and power to sensors in electrically challenging bioprocess environments is disclosed. An unconnected antenna is located within the bioprocess environment, preferably in the same plane as the primary powered antenna. This unconnected antenna, also referred to as reflective antenna, enhances and confines the electromagnetic field created by the powered antenna. This reflective antenna is incorporated in or proximate to the devices containing a sensor or communication device. In one embodiment, the reflective antenna is incorporated into the filter housing. In another embodiment, it is incorporated into the filtering element itself. In another embodiment, it is incorporated into or affixed on the disposable bioprocess components, such as bags and tubes.

公开(公告)号：US08383037B2

公开(公告)日：2013-02-26

申请号：US13414884

申请日：2012-03-08

申请人： Aaron Burke

发明人： Aaron Burke

IPC分类号： A61L2/00

CPC分类号： A61L2/081 ,  A61L2/087 ,  A61L2202/24

摘要： A system and method for implementing embedded electronics in environments where radiation or extreme temperatures are used is disclosed. Embedded electronics are affixed to various components of a pharmaceutical system, thereby enabling the customer to download pertinent information about the component, such as lot number, date of manufacturer, test parameters, etc. Additionally, these electronics allow an array of functions and features to be implemented, such as integrity tests and diagnostics. The electronics in the pharmaceutical components utilize a technology that is not as susceptible to radiation and extreme temperatures as traditional electronics.

摘要翻译： 公开了一种在使用辐射或极端温度的环境中实现嵌入式电子设备的系统和方法。 嵌入式电子设备固定在药物系统的各种组件上，从而使客户能够下载有关组件的相关信息，例如批号，制造商日期，测试参数等。此外，这些电子装置允许一系列功能和特征 实施，如​​完整性测试和诊断。 药物部件中的电子元件利用了不像传统电子产品那样易受辐射和极端温度影响的技术。