Optoelectronic Separation of Biomolecules
    1.
    发明申请
    Optoelectronic Separation of Biomolecules 审中-公开
    光电子分离生物分子

    公开(公告)号:US20070095667A1

    公开(公告)日:2007-05-03

    申请号:US11426222

    申请日:2006-06-23

    申请人: Aldrich Lau

    发明人: Aldrich Lau

    IPC分类号: C07K1/26 G01N27/00

    摘要: The present teachings relate to systems and methods for separation of substances such as cells, nucleic acids, and carbon nanotubes. The substances are combined with a separation medium in a liquid sample cavity, for example a microchannel, and transit through the separation by optically activated dielectrophoretic forces. The substances are advantageously labeled and visualized using a microscope and camera.

    摘要翻译: 本教导涉及用于分离诸如细胞,核酸和碳纳米管的物质的系统和方法。 这些物质与液体样品腔(例如微通道)中的分离介质组合,并通过光学活化的介电电泳力穿过分离。 使用显微镜和照相机有利地将物质标记和可视化。

    Devices and methods for optoelectronic manipulation of small particles
    4.
    发明授权
    Devices and methods for optoelectronic manipulation of small particles 有权
    用于光电子操纵小颗粒的装置和方法

    公开(公告)号:US08834698B2

    公开(公告)日:2014-09-16

    申请号:US12702137

    申请日:2010-02-08

    摘要: A method for sorting cells in a biological sample comprising a first type of cells and a second type of cells may comprise introducing the biological sample into a chamber comprising a first surface and a second surface, wherein the first surface is associated with a transparent electrode and the second surface is associated with a photoconductive portion of an electrode. The method may further comprise moving incident light and the photoconductive portion relative to one another so as to illuminate regions of the photoconductive portion and modulate an electric field in the chamber in proximity to the illuminated regions. The method may further comprise separating the first type of cells from the second type of cells in the chamber via dielectrophoretic movement of the first type of cells and the second type of cells caused by the modulated electric field, wherein a dielectrophoretic characteristic of at least one of the first type of cells and the second type of cells has been modified.

    摘要翻译: 用于分选生物样品中包含第一类型细胞和第二类型细胞的细胞的方法可以包括将生物样品引入包含第一表面和第二表面的室中,其中第一表面与透明电极相关联, 第二表面与电极的光电导部分相关联。 该方法还可以包括相对于彼此移动入射光和光电导部分,以照射光电导部分的区域并且调制在邻近照明区域的室中的电场。 该方法还可以包括通过由调制电场引起的第一类型的细胞和第二类型的细胞的介电电泳运动,将第一类型的细胞与腔室中的第二类型的细胞分离,其中至少一种的介电电泳特性 的第一类型的细胞和第二类型的细胞已被修改。