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公开(公告)号：US20110097782A1
公开(公告)日：2011-04-28
申请号：US12905777
申请日：2010-10-15
Applicant: Pei-Shin JIANG , Kun-Chan Wu , Yu-Ting Su , Chia-Yun Lin , Siou-Cing Su , Yuh-Jiuan Lin
Inventor： Pei-Shin JIANG , Kun-Chan Wu , Yu-Ting Su , Chia-Yun Lin , Siou-Cing Su , Yuh-Jiuan Lin
CPC classification number: C12N15/1013 , C12N15/1006
Abstract: A method for isolating nucleic acids is provided. The method includes providing a biological sample containing at least one nucleic acid, and mixing the biological sample with an isolating agent under a suitable condition to isolate the nucleic acids from the biological sample in single step, wherein the isolating agent contains 1-40 wt % of PEG and/or more than 30 wt % of low molecular weight alcohol, a salt, and a detergent. Isolated nucleic acids are bound to a solid support by changes in the solubility of nucleic acids. Additionally, the present invention further provides an isolating agent and kit for isolating nucleic acids.
Abstract translation: 提供了分离核酸的方法。 该方法包括提供含有至少一种核酸的生物样品，并在合适的条件下将生物样品与分离剂混合，以在单步骤中分离生物样品中的核酸，其中所述分离剂含有1-40重量％ 的PEG和/或大于30重量％的低分子量醇，盐和洗涤剂。 分离的核酸通过核酸溶解度的变化与固体支持物结合。 另外，本发明还提供了用于分离核酸的分离剂和试剂盒。
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2.发明授权Magnetic particles containing a copolymer core, magnetic layer and silicon layer 有权含有共聚物芯，磁性层和硅层的磁性颗粒公开(公告)号：US07868145B2
公开(公告)日：2011-01-11
申请号：US11822958
申请日：2007-07-11
Applicant: Kun Chan Wu , Hui-Ju Cho , Pei-Shin Jiang , Hsiang Yuan Huang , Wen-Hsun Kuo , Chi-Min Chau , Chih Hsien Su , Kun Feng Lee
Inventor： Kun Chan Wu , Hui-Ju Cho , Pei-Shin Jiang , Hsiang Yuan Huang , Wen-Hsun Kuo , Chi-Min Chau , Chih Hsien Su , Kun Feng Lee
IPC: C07K1/14 , C07K1/22 , C07K17/14 , C07K17/08 , C12P1/00 , C12N11/14 , C12N11/08 , G01N33/553 , G01N33/552 , G01N33/545
CPC classification number: G01N33/5434 , B22F1/02 , B82Y25/00 , C12N13/00 , C22C2202/02 , G01N2446/10 , H01F1/0054 , Y10S435/814 , Y10S530/811 , Y10S530/815 , Y10T428/2993
Abstract: A magnetic particle and fabrication method thereof. The magnetic particle comprises a polymer core, a magnetic material layer covering the polymer core, and a silicon containing layer covering the magnetic material layer. In addition, the magnetic particle may further comprise a coupling agent on the silicon containing layer, and an active molecule connected to the coupling agent. The magnetic particles provide controllable size, uniform diameter distribution, high magnetization, improved storage stability, and modified surface for targeting biomolecules for biomaterial separation and environmental analysis.
Abstract translation: 磁性颗粒及其制造方法。 磁性颗粒包括聚合物芯，覆盖聚合物芯的磁性材料层和覆盖磁性材料层的含硅层。 此外，磁性颗粒还可以包含在含硅层上的偶联剂和与偶联剂连接的活性分子。 磁性颗粒提供可控的尺寸，均匀的直径分布，高磁化强度，改善的储存稳定性，以及用于靶向生物分子用于生物材料分离和环境分析的改性表面。
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公开(公告)号：US20090017518A1
公开(公告)日：2009-01-15
申请号：US11822958
申请日：2007-07-11
Applicant: Kun Chan Wu , Hui-Ju Cho , Pei-Shin Jiang , Hsiang Yuan Huang , Wen-Hsun Kuo , Chi-Min Chau
Inventor： Kun Chan Wu , Hui-Ju Cho , Pei-Shin Jiang , Hsiang Yuan Huang , Wen-Hsun Kuo , Chi-Min Chau
CPC classification number: G01N33/5434 , B22F1/02 , B82Y25/00 , C12N13/00 , C22C2202/02 , G01N2446/10 , H01F1/0054 , Y10S435/814 , Y10S530/811 , Y10S530/815 , Y10T428/2993
Abstract: A magnetic particle and fabrication method thereof. The magnetic particle comprises a polymer core, a magnetic material layer covering the polymer core, and a silicon containing layer covering the magnetic material layer. In addition, the magnetic particle may further comprise a coupling agent on the silicon containing layer, and an active molecule connected to the coupling agent. The magnetic particles provide controllable size, uniform diameter distribution, high magnetization, improved storage stability, and modified surface for targeting biomolecules for biomaterial separation and environmental analysis.
Abstract translation: 磁性颗粒及其制造方法。 磁性颗粒包括聚合物芯，覆盖聚合物芯的磁性材料层和覆盖磁性材料层的含硅层。 此外，磁性颗粒还可以包含在含硅层上的偶联剂和与偶联剂连接的活性分子。 磁性颗粒提供可控的尺寸，均匀的直径分布，高磁化强度，改善的储存稳定性，以及用于靶向生物分子用于生物材料分离和环境分析的改性表面。
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公开(公告)号：US20050100922A1
公开(公告)日：2005-05-12
申请号：US10674403
申请日：2003-10-01
Applicant: Kun Feng Lee , Pei-Shin Jiang , Yuh-Jiuan Lin
Inventor： Kun Feng Lee , Pei-Shin Jiang , Yuh-Jiuan Lin
CPC classification number: G01N35/08 , G01N2035/00326
Abstract: A fluid analyzing apparatus. The fluid analyzing apparatus sequentially or simultaneously detects and analyzes a multiplex fluid sample with suitable analyzing elements. Meanwhile, the fluid analyzing apparatus may be disassembled to a first unit, a second unit and a third unit, such that the analyzing elements therein are easily disposed and replaced. The fluid analyzing apparatus analyzes and detects the multiplex fluid sample by allowing the multiplex fluid sample to sequentially or simultaneously flow through a plurality of target chambers. The fluid analyzing apparatus sequentially or simultaneously transports the multiplex fluid sample to the target chambers, thereby enhancing the speed and analysis thereof.
Abstract translation: 流体分析装置。 流体分析装置顺序或同时地检测并分析具有合适的分析元件的多重流体样品。 同时，流体分析装置可以分解成第一单元，第二单元和第三单元，使得其中的分析元件容易地设置和更换。 流体分析装置通过使多重流体样品依次或同时流过多个目标室来分析和检测多重流体样品。 流体分析装置顺序或同时地将多重流体样品输送到目标室，从而提高其速度和分析。
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公开(公告)号：US07579436B2
公开(公告)日：2009-08-25
申请号：US11681094
申请日：2007-03-01
Applicant: Pei-Ching Shih , Pei-Shin Jiang , Wen-Hsun Kuo , Yuh-Jiuan Lin
Inventor： Pei-Ching Shih , Pei-Shin Jiang , Wen-Hsun Kuo , Yuh-Jiuan Lin
IPC: C07K7/06
CPC classification number: G01N29/036 , C07K7/06 , G01N33/54373 , G01N33/84 , G01N2291/0257 , Y10T436/175383 , Y10T436/18
Abstract: A peptide compound for measuring sulfur compound and ammonia and measurement method and device using the compound. The method comprises contacting an analyte with a sensory device coated with the peptide compound to produce a signal, processing the signal to produce a result, and comparing the result with a database to define the presence of the sulfur compound and ammonia in the analyte.
Abstract translation: 用于测量硫化合物和氨的肽化合物和使用该化合物的测量方法和装置。 该方法包括使分析物与涂覆有肽化合物的感觉装置接触以产生信号，处理信号以产生结果，并将结果与数据库进行比较以定义分析物中硫化合物和氨的存在。
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Patent Agency Ranking
6.发明授权Method and device for measuring sulfur compound and/or ammonia based on a sensory unit coated with at least one novel peptide 有权用于测量基于涂覆有至少一种新型肽的感官单元的硫化合物和/或氨的方法和装置公开(公告)号：US07267989B2
公开(公告)日：2007-09-11
申请号：US10321652
申请日：2002-12-18
Applicant: Pei-Ching Shih , Pei-Shin Jiang , Wen-Hsun Kuo , Yuh-Jiuan Lin
Inventor： Pei-Ching Shih , Pei-Shin Jiang , Wen-Hsun Kuo , Yuh-Jiuan Lin
IPC: G01N33/00
CPC classification number: G01N29/036 , C07K7/06 , G01N33/54373 , G01N33/84 , G01N2291/0257 , Y10T436/175383 , Y10T436/18
Abstract: A peptide compound for measuring sulfur compound and ammonia and measurement method and device using the compound. The method comprises contacting an analyte with a sensory device coated with the peptide compound to produce a signal, processing the signal to produce a result, and comparing the result with a database to define the presence of the sulfur compound and ammonia in the analyte.
Abstract translation: 用于测量硫化合物和氨的肽化合物和使用该化合物的测量方法和装置。 该方法包括使分析物与涂覆有肽化合物的感觉装置接触以产生信号，处理信号以产生结果，并将结果与数据库进行比较以定义分析物中硫化合物和氨的存在。
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公开(公告)号：US09006419B2
公开(公告)日：2015-04-14
申请号：US12905777
申请日：2010-10-15
Applicant: Pei-Shin Jiang , Kun-Chan Wu , Yu-Ting Su , Chia-Yun Lin , Siou-Cing Su , Yuh-Jiuan Lin
Inventor： Pei-Shin Jiang , Kun-Chan Wu , Yu-Ting Su , Chia-Yun Lin , Siou-Cing Su , Yuh-Jiuan Lin
CPC classification number: C12N15/1013 , C12N15/1006
Abstract: A method for isolating nucleic acids is provided. The method includes providing a biological sample containing at least one nucleic acid, and mixing the biological sample with an isolating agent under a suitable condition to isolate the nucleic acids from the biological sample in single step, wherein the isolating agent contains 1-40 wt % of PEG and/or more than 30 wt % of low molecular weight alcohol, a salt, and a detergent. Isolated nucleic acids are bound to a solid support by changes in the solubility of nucleic acids. Additionally, the present invention further provides an isolating agent and kit for isolating nucleic acids.
Abstract translation: 提供了分离核酸的方法。 该方法包括提供含有至少一种核酸的生物样品，并在合适的条件下将生物样品与分离剂混合，以在单步骤中分离生物样品中的核酸，其中所述分离剂含有1-40重量％ 的PEG和/或大于30重量％的低分子量醇，盐和洗涤剂。 分离的核酸通过核酸溶解度的变化与固体支持物结合。 另外，本发明还提供了用于分离核酸的分离剂和试剂盒。
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公开(公告)号：US08216826B2
公开(公告)日：2012-07-10
申请号：US12251274
申请日：2008-10-14
Applicant: Kun Feng Lee , Pei-Shin Jiang , Yuh-Jiuan Lin
Inventor： Kun Feng Lee , Pei-Shin Jiang , Yuh-Jiuan Lin
IPC: C12M1/34
CPC classification number: G01N35/08 , G01N2035/00326
Abstract: A fluid analyzing apparatus. The fluid analyzing apparatus sequentially or simultaneously detects and analyzes a multiplex fluid sample with suitable analyzing elements. Meanwhile, the fluid analyzing apparatus may be disassembled to a first unit, a second unit and a third unit, such that the analyzing elements therein are easily disposed and replaced. The fluid analyzing apparatus analyzes and detects the multiplex fluid sample by allowing the multiplex fluid sample to sequentially or simultaneously flow through a plurality of target chambers. The fluid analyzing apparatus sequentially or simultaneously transports the multiplex fluid sample to the target chambers, thereby enhancing the speed and analysis thereof.
Abstract translation: 流体分析装置。 流体分析装置顺序或同时地检测并分析具有合适的分析元件的多重流体样品。 同时，流体分析装置可以分解成第一单元，第二单元和第三单元，使得其中的分析元件容易地设置和更换。 流体分析装置通过使多重流体样品依次或同时流过多个目标室来分析和检测多重流体样品。 流体分析装置顺序或同时地将多重流体样品输送到目标室，从而提高其速度和分析。
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9.发明申请REAGENT, CHAOTROPIC AGENT, AND REAGENT KIT FOR AND APPLICATIONS OF ISOLATING NUCLEIC ACID BY USE OF MAGNETIC CELLULOSE MATERIAL 有权通过使用磁性纤维素材料分离核酸的试剂，化学试剂和试剂盒和应用公开(公告)号：US20110166338A1
公开(公告)日：2011-07-07
申请号：US12935681
申请日：2008-04-02
Applicant: Pei-Shin Jiang , Yu-Ting Su , Kun-Chan Wu , Hui-Ju Cho , Wen-Hsun Kuo , Yuh-Jiuan Lin , Yi-Ling Li , Cheng-Chun Kuan
Inventor： Pei-Shin Jiang , Yu-Ting Su , Kun-Chan Wu , Hui-Ju Cho , Wen-Hsun Kuo , Yuh-Jiuan Lin , Yi-Ling Li , Cheng-Chun Kuan
CPC classification number: C07H1/06 , C07H21/00 , C12N15/1013
Abstract: Disclosed are a chaotropic agent; a reagent including a chaotropic agent and a lithium salt; a reagent kit including a chaotropic agent; a chaotropic agent, a reagent, a reagent kit, and a method for isolating a nucleic acid by use of a magnetic cellulose material; a method for binding a nucleic acid to a magnetic cellulose material; a method for isolating a nucleic acid; and a method for purifying a chromosome DNA. It is required that each of the chaotropic agents, the reagents, and the reagent kits works with at least one solid-phase, magnetic cellulose-containing carrier to isolate a nucleic acid from non-nucleic acid substances. In addition, each chaotropic agent includes an alcohol substance and a substrate solution for adjusting the alcohol substance to an appropriate concentration and thereby promoting binding of the nucleic acid in a sample to the magnetic cellulose.
Abstract translation: 公开了一种离液剂; 包含离液剂和锂盐的试剂; 包含离液剂的试剂盒; 离液剂，试剂，试剂盒和通过使用磁性纤维素材料分离核酸的方法; 将核酸与磁性纤维素材料结合的方法; 分离核酸的方法; 以及纯化染色体DNA的方法。 需要每种离液剂，试剂和试剂盒与至少一种固相含磁性纤维素的载体一起工作，以将核酸与非核酸物质分离。 此外，各离液剂包括醇物质和用于将醇物质调节至适当浓度的底物溶液，从而促进样品中的核酸与磁性纤维素的结合。
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公开(公告)号：US20090041623A1
公开(公告)日：2009-02-12
申请号：US12251274
申请日：2008-10-14
Applicant: Kun Feng LEE , Pei-Shin Jiang , Yuh-Jiuan Lin
Inventor： Kun Feng LEE , Pei-Shin Jiang , Yuh-Jiuan Lin
CPC classification number: G01N35/08 , G01N2035/00326
Abstract: A fluid analyzing apparatus. The fluid analyzing apparatus sequentially or simultaneously detects and analyzes a multiplex fluid sample with suitable analyzing elements. Meanwhile, the fluid analyzing apparatus may be disassembled to a first unit, a second unit and a third unit, such that the analyzing elements therein are easily disposed and replaced. The fluid analyzing apparatus analyzes and detects the multiplex fluid sample by allowing the multiplex fluid sample to sequentially or simultaneously flow through a plurality of target chambers. The fluid analyzing apparatus sequentially or simultaneously transports the multiplex fluid sample to the target chambers, thereby enhancing the speed and analysis thereof.
Abstract translation: 流体分析装置。 流体分析装置顺序或同时地检测并分析具有合适的分析元件的多重流体样品。 同时，流体分析装置可以分解成第一单元，第二单元和第三单元，使得其中的分析元件容易地设置和更换。 流体分析装置通过使多重流体样品依次或同时流过多个目标室来分析和检测多重流体样品。 流体分析装置顺序或同时地将多重流体样品输送到目标室，从而提高其速度和分析。
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