摘要:
A double-structured tissue implant and a method for preparation and use thereof for implantation into tissue defects. The double-structured tissue implant comprising a primary scaffold and a secondary scaffold consisting of a soluble collagen solution in combination with a non-ionic surfactant generated and positioned within the primary scaffold. A stand alone secondary scaffold implant or unit. A process for preparation of the double-structured implant or the stand alone secondary scaffold comprising lyophilization and dehydrothermal treatment.
摘要:
A double-structured tissue implant (DSTI) and a method for preparation and use thereof for implantation into tissue defects. The double-structured tissue implant for differentiation, growth and transformation of cells, stem cells, mesenchymal stem cells and bone marrow stem cells. DSTI comprising a primary scaffold and a secondary scaffold consisting of a soluble collagen solution in combination with a non-ionic surfactant generated and positioned within the primary scaffold.
摘要:
A system for determining image intensity of a radiograph includes an illuminator for providing lighting to the radiograph, an image reference standard having a predetermined color, a digital imaging device for obtaining a digital image of the radiograph and the image reference standard, a computer for receiving and storing the digital image and for executing programs, and an image analysis program being executed on the computer for providing a first image intensity value of a target area in the radiograph and a second image intensity value of the image reference standard and for computing a normalized image intensity value of the target area using the first and second image intensity values. In one embodiment, the image reference standard is an image reference standard of a black color or a white color.
摘要:
Methods for compression molding through holes in polymer layers are provided, as are the resulting patterned polymer layers. Two key aspects of the invention are provision of a mold and substrate having different mechanical hardness, and provision of room for local flow of material. These aspects of the invention facilitate formation of through holes by compression molding that are not blocked or partially blocked by undesirable material. These polymer layers can be formed into three dimensional patterned structures by bonding patterned layers together. Since the layers include through holes, a three-dimensional polymer pattern can be formed. These patterned polymer layers and three dimensionally patterned polymer constructs have a wide variety of applications. For example, these constructs can be used for fabrication of micro-fluidic devices, and/or can be used for various medical and biological applications including drug delivery devices and tissue engineering devices.
摘要:
Sensors and systems for electrical, electrochemical, or topographical analysis, as well as methods of fabricating these sensors are provided. The sensors include a cantilever and one or more probes, each of which has an electrode at its tip. The tips of the probes are sharp, with a radius of curvature of less than about 50 nm. In addition, the probes have a high aspect ratio of more than about 19:1. The sensors are suitable for both Atomic Force Microscopy and Scanning Electrochemical Microscopy.
摘要:
The invention broadly comprises a system and method for a secure web-based digital storage means comprising multiple user selectable security levels, each security level requiring a unique authentication means for access, said storage means providing for the highly secure storage of digital information.
摘要:
A method for use of a double-structured tissue implant or a secondary scaffold stand alone implant for treatment of tissue defects. The double-structured tissue implant comprising a primary scaffold and a secondary scaffold consisting of a soluble collagen solution in combination with a non-ionic surfactant generated and positioned within the primary scaffold. A stand alone secondary scaffold implant or unit.
摘要:
A method for in vivo, ex vivo and in vitro regeneration of cartilage, collagen and bone remodeling by intermittently applied hydrostatic pressure consisting of repeated periods of applied hydrostatic pressure followed and interrupted by periods of recovery. The intermittent hydrostatic pressure is applied at physiological levels 5-10 MPA for an interval of 4 hours followed by a recovery period up to about 20 hours. The interval loading results in the selective inhibition of matrix degrading enzymes, pro-inflammatory cytokines and chemokines that attract inflammatory cells into the joint cavity and in selective decrease of gene expression of growth factors that are inhibitory to type II collagen expression.
摘要:
A method for use of a double-structured tissue implant or a secondary scaffold stand alone implant for treatment of tissue defects. The double-structured tissue implant comprising a primary scaffold and a secondary scaffold consisting of a soluble collagen solution in combination with a non-ionic surfactant generated and positioned within the primary scaffold. A stand alone secondary scaffold implant or unit.
摘要:
A method of providing a registration label for a vehicle. The method includes determining registration information, the registration information being at least partially indicative of an identity of the vehicle; and then using the information to generate the label by causing printed information to be provided on the label, and by causing tag data to be stored in a tag data store. The printed information and tag data are at least partially indicative of the registration information so that the registration information can be checked by a suitable reader once the label is attached to the associated vehicle.