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    Combination therapy and antibody panels
    1.
    发明申请
    Combination therapy and antibody panels 审中-公开

    公开(公告)号：US20070134248A1

    公开(公告)日：2007-06-14

    申请号：US11297167

    申请日：2005-12-08

    申请人： Dan Denney ,  Keri Marie Tate ,  Thomas P. Theriault

    发明人： Dan Denney ,  Keri Marie Tate ,  Thomas P. Theriault

    IPC分类号： A61K39/395 ,  A61K39/00

    CPC分类号： C07K16/4283 ,  C07K16/3061

    摘要： The present invention provides combination immunotherapy for Non-Hodgkin's Lymphoma. In one embodiment, the combination immunotherapy first provides for the administration of a monoclonal antibody directed to a non-idotypic portion of a lymphoma cell surface immunoglobulin (e.g. a framework region of a variable region). The combination immunotherapy next provides for the administration of an immunogenic composition comprising at least a portion of the same lymphoma cell surface immunoglobulin, whether an idiotypic portion or non-idiotypic portion.

    Duplex probes for hybridization reactions
    2.
    发明授权
    Duplex probes for hybridization reactions 失效
    用于杂交反应的双相探针

    公开(公告)号：US06448013B1

    公开(公告)日：2002-09-10

    申请号：US09721801

    申请日：2000-11-22

    申请人： Lyle Arnold ,  Tod Bedilion ,  Erik Bieldanes ,  Thomas P. Theriault ,  Warren Lei

    发明人： Lyle Arnold ,  Tod Bedilion ,  Erik Bieldanes ,  Thomas P. Theriault ,  Warren Lei

    IPC分类号： C12Q168

    CPC分类号： C12Q1/6837 ,  C12Q1/6851 ,  Y10T436/143333 ,  C12Q2545/114 ,  C12Q2531/113 ,  C12Q2565/501

    摘要： Methods are provide for quantitatively determining the amount of polynucleotides in a sample. In one method, the distinct polynucleotide targets and standard polynucleotide targets are contacted with detectable probes and independently detectable single or double stranded complements to the standard targets under hybridization conditions. The hybridization pattern from the probe is compared to the hybridization pattern from the standard sequences to obtain quantitative information about the genetic profile of the labeled nucleic acid sample. Also provided are kits for the use of the methods.

    摘要翻译： 提供了定量测定样品中多核苷酸的量的方法。 在一种方法中，在杂交条件下，将不同的多核苷酸靶标和标准多核苷酸靶标与可检测的探针和标准靶的独立可检测的单链或双链互补物接触。 将来自探针的杂交模式与来自标准序列的杂交模式进行比较，以获得关于标记的核酸样品的遗传图谱的定量信息。 还提供了使用方法的工具包。

    NOVEL DECENCY FILTRATION TOOLS AND THEIR USE IN INTERFACING SYSTEMS
    4.
    发明申请
    NOVEL DECENCY FILTRATION TOOLS AND THEIR USE IN INTERFACING SYSTEMS 审中-公开

    公开(公告)号：US20190342246A1

    公开(公告)日：2019-11-07

    申请号：US16403607

    申请日：2019-05-05

    申请人： Thomas P. Theriault ,  Mark Dingman

    发明人： Thomas P. Theriault ,  Mark Dingman

    IPC分类号： H04L12/58 ,  H04L29/06

    摘要： The present invention is directed to novel tools and systems that provide methods to monitor and police platforms for interfacing designed to facilitate the exchange of communications between two or more users. In particular, the present invention provides anonymous and secure methods to capture, monitor, and score users of an interfacing platform, such as a dating platform, based on inappropriate and indecent behavior on the interfacing platform.

    Normalization control for hybridization reactions
    8.
    发明授权
    Normalization control for hybridization reactions 失效
    杂交反应的归一化控制

    公开(公告)号：US06423535B1

    公开(公告)日：2002-07-23

    申请号：US09449059

    申请日：1999-11-24

    申请人： Lyle Arnold ,  Tod Bedilion ,  Erik Bjeldanes ,  Thomas P. Theriault ,  Warren Lei

    发明人： Lyle Arnold ,  Tod Bedilion ,  Erik Bjeldanes ,  Thomas P. Theriault ,  Warren Lei

    IPC分类号： C12M134

    CPC分类号： C12Q1/6837 ,  C12Q1/6851 ,  Y10T436/143333 ,  C12Q2545/114 ,  C12Q2531/113 ,  C12Q2565/501

    摘要： Methods are provide for quantitatively determining the amount of polynucleotides in a sample. In one method, the distinct polynucleotide targets and standard polynucleotide targets are contacted with detectable probes and independently detectable single or double stranded complements to the standard targets under hybridization conditions. The hybridization pattern from the probe is compared to the hybridization pattern from the standard sequences to obtain quantitative information about the genetic profile of the labeled nucleic acid sample. Also provided are kits for the use of the methods.

    摘要翻译： 提供了定量测定样品中多核苷酸的量的方法。 在一种方法中，在杂交条件下，将不同的多核苷酸靶标和标准多核苷酸靶标与可检测的探针和标准靶标的独立可检测的单链或双链互补物接触。 将来自探针的杂交模式与来自标准序列的杂交模式进行比较，以获得关于标记的核酸样品的遗传图谱的定量信息。 还提供了使用方法的工具包。