Transdermally absorbable Donepezil Preparation
    5.
    发明申请
    Transdermally absorbable Donepezil Preparation 审中-公开
    透皮吸收多奈哌齐制剂

    公开(公告)号:US20090175929A1

    公开(公告)日:2009-07-09

    申请号:US12227201

    申请日:2007-05-08

    IPC分类号: A61K9/70 A61K31/4353

    摘要: Disclosed is a donepezil-containing transdermally absorbable preparation which develops reduced adverse side effects and shows a satisfactory level of therapeutic effect. The preparation comprises an adhesive and a donepezil component (containing crystalline donepezil having type-B crystal polymorphism) and/or a salt thereof, wherein the donepezil component or the salt thereof is contained in an amount of 9 to 50% by mass relative to the total weight of the adhesive. The preparation (particularly, one having a non-aqueous adhesive layer) shows an excellent penetration of donepezil and/or a salt thereof into the skin, retains good stability of the active ingredient therein, and is remarkably reduced in local stimulation and adverse side effects.

    摘要翻译: 公开了一种含多奈哌齐的透皮吸收制剂,其具有减少的副作用,并显示令人满意的治疗效果。 该制剂包含粘合剂和多奈哌齐组分(含有具有B型晶体多晶型的结晶多奈哌齐)和/或其盐,其中所述多奈哌齐组分或其盐的含量相对于所述组合物为9〜50质量% 粘合剂的总重量。 该制剂(特别是具有非水性粘合剂层的制剂)显示出多奈哌齐和/或其盐对皮肤的渗透性优异,保持其中活性成分的良好稳定性,并且局部刺激和不良副作用显着降低 。

    ELECTROPHORESIS CHIP
    6.
    发明申请
    ELECTROPHORESIS CHIP 有权
    电泳芯片

    公开(公告)号:US20090166206A1

    公开(公告)日:2009-07-02

    申请号:US12344009

    申请日:2008-12-24

    申请人: WATARU HATTORI

    发明人: WATARU HATTORI

    IPC分类号: G01N27/00

    CPC分类号: G01N27/44717

    摘要: An electrophoresis chip is provided with a channel that is filled with a solution in which a sample is dissolved, the electrophoresis chip being configured to carry out electrophoresis by applying voltage along the channel in a state in which the channel is hermetically sealed to separate the sample in the channel, and after this electrophoresis is performed, to carry out mass spectrometry by scanning a laser along the channel in a state in which the channel is open to an environment in which gas is present. A pattern is formed on the bottom surface of the channel to hold the solution as droplets. This pattern is made into a pattern in which hydrophilic areas are surrounded by hydrophobic areas and side-walls of the channel.

    摘要翻译: 电泳芯片设置有填充有样品溶解的溶液的通道,电泳芯片被配置为通过在通道被密封的状态下施加电压以进行电泳,以分离样品 在该通道中,并且在进行该电泳之后,通过在通道对存在气体的环境开放的状态下沿着通道扫描激光来进行质谱分析。 在通道的底表面上形成图案以将溶液保持为液滴。 该图案被制成其中亲水区域被通道的疏水区域和侧壁包围的图案。

    DIAGNOSIS SUPPORTING SYSTEM
    7.
    发明申请
    DIAGNOSIS SUPPORTING SYSTEM 审中-公开
    诊断支持系统

    公开(公告)号:US20090070045A1

    公开(公告)日:2009-03-12

    申请号:US12263147

    申请日:2008-10-31

    IPC分类号: G06F19/00 G06F17/18

    摘要: A diagnosis supporting system (10) includes a diagnosis data obtaining unit (20) that obtains diagnosis data in which a movement parameter reflecting a movement speed of each component in separating a sample collected from a test subject into plural components with a chip (12) and a character of each component is in correspondence, a parameter storing unit (34) that stores the movement parameter of a characteristic component showing a state of suffering from a specific disease in correspondence with the disease, a relationship data storing unit (35) that stores relationship data showing a relationship between the character of the characteristic component and a possibility of suffering from a specific disease, a detecting unit (21) that detects the characteristic component from the diagnosis data based on the movement parameter of the characteristic component and the movement parameter of the diagnosis data by making reference to the parameter storing unit (34), and an inference processing unit (22) that infers the possibility that the test subject is suffering by making reference to the relationship data storing unit (35) based on the character of the detected characteristic component.

    摘要翻译: 诊断支持系统(10)包括诊断数据获取单元(20),该诊断数据获取单元(20)获取诊断数据,其中,用芯片(12)将反映从测试对象收集的样本的每个组件的移动速度反映成多个组件的移动参数, 并且每个部件的字符相对应,存储与疾病相对应地显示出患有特定疾病的状态的特征部件的移动参数的参数存储部(34),关系数据存储部(35),其中, 存储表示特征成分的特征与患有特定疾病的可能性之间的关系的关系数据,根据特征成分的移动参数和运动来检测来自诊断数据的特征成分的检测部(21) 参考存储单元(34)的诊断数据的参数以及推断处理 (22),其基于检测到的特征分量的特性,参考关系数据存储单元(35)推测测试对象遭受的可能性。

    Electromagnetic wave transmission sheet and electromagnetic wave transmission device

    公开(公告)号:US09853501B2

    公开(公告)日:2017-12-26

    申请号:US14375655

    申请日:2012-12-20

    申请人: Wataru Hattori

    发明人: Wataru Hattori

    IPC分类号: H02J17/00 H04B13/00

    摘要: An edge portion which defines a planar shape has two long end sides (108a, 108b) which extend in parallel to each other, and two short end sides (107, 109) which have parallel portions extending in parallel to each other. The two long end sides and the two short end sides are reflection terminals. The parallel portion of the first short end side (107) includes a first portion (107a) and a second portion (107b). The positions of the antinodes of a first standing wave formed by a traveling wave directed toward the first portion (107a) and a reflected wave of the traveling wave and a second standing wave formed by a traveling wave directed toward the second portion (107b) and a reflected wave of the traveling wave in a direction substantially parallel to the long end sides (108a, 108b) are deviated by ¼ of the wavelength of an electromagnetic wave propagating through an electromagnetic wave transmission sheet.