-
公开(公告)号：US20240027396A1
公开(公告)日：2024-01-25
申请号：US18324026
申请日：2023-05-25
Applicant: BERKELEY LIGHTS, INC.
Inventor： Kevin T. Chapman , Igor Y. Khandros , Gaetan L. Mathieu , J. Tanner Nevill , Ming C. Wu
IPC: G01N27/447 , B01L3/00 , B03C5/00 , B03C5/02
CPC classification number: G01N27/44791 , B01L3/502761 , B03C5/005 , B03C5/026 , B01L2200/0668 , B01L2300/0816 , B01L2300/0819 , B01L2300/0877 , B01L2400/0424 , B01L2400/086 , B03C2201/26 , B01L2400/0454
Abstract: Individual biological micro-objects can be deterministically selected and moved into holding pens in a micro-fluidic device. A flow of a first liquid medium can be provided to the pens. Physical pens can be structured to impede a direct flow of the first medium into a second medium in the pens while allowing diffusive mixing of the first medium and the second medium. Virtual pens can allow a common flow of medium to multiple ones of the pens.
-
公开(公告)号：US20180259482A1
公开(公告)日：2018-09-13
申请号：US15842124
申请日：2017-12-14
Applicant: Berkeley Lights, Inc.
Inventor： Kevin T. Chapman , Igor Y. Khandros , Gaetan L. Mathieu , J. Tanner Nevill , Ming C. Wu
IPC: G01N27/447 , B01L3/00 , B03C5/00 , B03C5/02
Abstract: Individual biological micro-objects can be deterministically selected and moved into holding pens in a micro-fluidic device. A flow of a first liquid medium can be provided to the pens. Physical pens can be structured to impede a direct flow of the first medium into a second medium in the pens while allowing diffusive mixing of the first medium and the second medium. Virtual pens can allow a common flow of medium to multiple ones of the pens.
-
公开(公告)号：US10800652B2
公开(公告)日：2020-10-13
申请号：US16123882
申请日：2018-09-06
Applicant: Berkeley Lights, Inc.
Inventor： Keith J. Breinlinger , Daniele Malleo , Gaetan L. Mathieu , J. Tanner Nevill , Alexander H. Slocum , Mark P. White
IPC: B81B7/02 , B03C5/00 , B03C5/02 , G01N27/447 , B03C7/02 , G01N33/543 , B01L3/00 , C12M3/06 , C12M1/00 , C12M1/34 , G01N33/50
Abstract: A group of micro-objects in a holding pen in a micro-fluidic device can be selected and moved to a staging area, from which the micro-objects can be exported from the micro-fluidic device. The micro-fluidic device can have a plurality of holding pens, and each holding pen can isolate micro-objects located in the holding pen from micro-objects located in the other holding pens or elsewhere in the micro-fluidic device. The selected group of micro-objects can comprise one or more biological cells, such as a clonal population of cells. Embodiments of the invention can thus select a particular group of clonal cells in a micro-fluidic device, move the clonal cells to a staging area, and export the clonal cells from the micro-fluidic device while maintaining the clonal nature of the exported group.
-
公开(公告)号：US20190152771A1
公开(公告)日：2019-05-23
申请号：US16123882
申请日：2018-09-06
Applicant: Berkeley Lights, Inc.
Inventor： Keith J. Breinlinger , Daniele Malleo , Gaetan L. Mathieu , J. Tanner Nevill , Alexander H. Slocum , Mark P. White
Abstract: A group of micro-objects in a holding pen in a micro-fluidic device can be selected and moved to a staging area, from which the micro-objects can be exported from the micro-fluidic device. The micro-fluidic device can have a plurality of holding pens, and each holding pen can isolate micro-objects located in the holding pen from micro-objects located in the other holding pens or elsewhere in the micro-fluidic device. The selected group of micro-objects can comprise one or more biological cells, such as a clonal population of cells. Embodiments of the invention can thus select a particular group of clonal cells in a micro-fluidic device, move the clonal cells to a staging area, and export the clonal cells from the micro-fluidic device while maintaining the clonal nature of the exported group.
-
公开(公告)号：US09617145B2
公开(公告)日：2017-04-11
申请号：US14520510
申请日：2014-10-22
Applicant: Berkeley Lights, Inc.
Inventor： Keith J. Breinlinger , Daniele Malleo , Gaetan L. Mathieu , J. Tanner Nevill , Alexander H. Slocum , Mark P. White
CPC classification number: B81B7/02 , B01L3/502761 , B01L2200/027 , B01L2200/0652 , B01L2200/0668 , B01L2300/044 , B01L2300/0636 , B01L2300/0645 , B01L2300/0816 , B01L2300/0819 , B01L2300/0829 , B01L2300/0851 , B01L2300/0864 , B01L2300/087 , B01L2300/0877 , B01L2400/0424 , B01L2400/0433 , B01L2400/0454 , B01L2400/086 , B03C5/005 , B03C5/026 , B03C7/023 , B03C2201/26 , C12M23/16 , C12M41/46 , C12M47/02 , G01N27/447 , G01N27/44756 , G01N27/44791 , G01N33/5023 , G01N33/543 , G01N33/54326 , G01N35/10
Abstract: A group of micro-objects in a holding pen in a micro-fluidic device can be selected and moved to a staging area, from which the micro-objects can be exported from the micro-fluidic device. The micro-fluidic device can have a plurality of holding pens, and each holding pen can isolate micro-objects located in the holding pen from micro-objects located in the other holding pens or elsewhere in the micro-fluidic device. The selected group of micro-objects can comprise one or more biological cells, such as a clonal population of cells. Embodiments of the invention can thus select a particular group of clonal cells in a micro-fluidic device, move the clonal cells to a staging area, and export the clonal cells from the micro-fluidic device while maintaining the clonal nature of the exported group.
-
Patent Agency Ranking
公开(公告)号：US20140116881A1
公开(公告)日：2014-05-01
申请号：US14060117
申请日：2013-10-22
Applicant: Berkeley Lights, Inc.
Inventor： Kevin T. Chapman , Igor Y. Khandros , Gaetan L. Mathieu , J. Tanner Nevill , Ming C. Wu
IPC: G01N27/447
CPC classification number: G01N27/44791 , B01L3/502761 , B01L2200/0668 , B01L2300/0816 , B01L2300/0819 , B01L2300/0877 , B01L2400/0424 , B01L2400/0454 , B01L2400/086 , B03C5/005 , B03C5/026 , B03C2201/26
Abstract: Individual biological micro-objects can be deterministically selected and moved into holding pens in a micro-fluidic device. A flow of a first liquid medium can be provided to the pens. Physical pens can be structured to impede a direct flow of the first medium into a second medium in the pens while allowing diffusive mixing of the first medium and the second medium. Virtual pens can allow a common flow of medium to multiple ones of the pens.
Abstract translation: 可以确定性地选择各个生物微物体并将其移动到微流体装置中的保持笔中。 可以向笔提供第一液体介质的流动。 物理笔可被构造成妨碍第一介质直接流入笔中的第二介质，同时允许第一介质和第二介质的扩散混合。 虚拟笔可以允许中等到笔的多个笔的共同流动。
-
公开(公告)号：US09857333B2
公开(公告)日：2018-01-02
申请号：US14060117
申请日：2013-10-22
Applicant: Berkeley Lights, Inc.
Inventor： Kevin T. Chapman , Igor Y. Khandros , Gaetan L. Mathieu , J. Tanner Nevill , Ming C. Wu
IPC: B01L3/00 , G01N27/447 , G01N27/26 , B03C5/00 , B03C5/02
CPC classification number: G01N27/44791 , B01L3/502761 , B01L2200/0668 , B01L2300/0816 , B01L2300/0819 , B01L2300/0877 , B01L2400/0424 , B01L2400/0454 , B01L2400/086 , B03C5/005 , B03C5/026 , B03C2201/26
Abstract: Individual biological micro-objects can be deterministically selected and moved into holding pens in a micro-fluidic device. A flow of a first liquid medium can be provided to the pens. Physical pens can be structured to impede a direct flow of the first medium into a second medium in the pens while allowing diffusive mixing of the first medium and the second medium. Virtual pens can allow a common flow of medium to multiple ones of the pens.
-
公开(公告)号：US20170355595A1
公开(公告)日：2017-12-14
申请号：US15439506
申请日：2017-02-22
Applicant: Berkeley Lights, Inc.
Inventor： Keith J. Breinlinger , Daniele Malleo , Gaetan L. Mathieu , J. Tanner Nevill , Alexander H. Slocum , Mark P. White
IPC: B81B7/02 , B01L3/00 , B03C5/02 , G01N33/543 , B03C5/00 , G01N33/50 , C12M1/34 , G01N27/447
CPC classification number: B81B7/02 , B01L3/502761 , B01L2200/027 , B01L2200/0652 , B01L2200/0668 , B01L2300/044 , B01L2300/0636 , B01L2300/0645 , B01L2300/0816 , B01L2300/0819 , B01L2300/0829 , B01L2300/0851 , B01L2300/0864 , B01L2300/087 , B01L2300/0877 , B01L2400/0424 , B01L2400/0433 , B01L2400/0454 , B01L2400/086 , B03C5/005 , B03C5/026 , B03C7/023 , B03C2201/26 , C12M23/16 , C12M41/46 , C12M47/02 , G01N27/447 , G01N27/44756 , G01N27/44791 , G01N33/5023 , G01N33/543 , G01N33/54326 , G01N35/10
Abstract: A group of micro-objects in a holding pen in a micro-fluidic device can be selected and moved to a staging area, from which the micro-objects can be exported from the micro-fluidic device. The micro-fluidic device can have a plurality of holding pens, and each holding pen can isolate micro-objects located in the holding pen from micro-objects located in the other holding pens or elsewhere in the micro-fluidic device. The selected group of micro-objects can comprise one or more biological cells, such as a clonal population of cells. Embodiments of the invention can thus select a particular group of clonal cells in a micro-fluidic device, move the clonal cells to a staging area, and export the clonal cells from the micro-fluidic device while maintaining the clonal nature of the exported group.
-
公开(公告)号：US20170113231A9
公开(公告)日：2017-04-27
申请号：US14520510
申请日：2014-10-22
Applicant: Berkeley Lights, Inc.
Inventor： Keith J. Breinlinger , Daniele Malleo , Gaetan L. Mathieu , J. Tanner Nevill , Alexander H. Slocum , Mark P. White
CPC classification number: B81B7/02 , B01L3/502761 , B01L2200/027 , B01L2200/0652 , B01L2200/0668 , B01L2300/044 , B01L2300/0636 , B01L2300/0645 , B01L2300/0816 , B01L2300/0819 , B01L2300/0829 , B01L2300/0851 , B01L2300/0864 , B01L2300/087 , B01L2300/0877 , B01L2400/0424 , B01L2400/0433 , B01L2400/0454 , B01L2400/086 , B03C5/005 , B03C5/026 , B03C7/023 , B03C2201/26 , C12M23/16 , C12M41/46 , C12M47/02 , G01N27/447 , G01N27/44756 , G01N27/44791 , G01N33/5023 , G01N33/543 , G01N33/54326 , G01N35/10
Abstract: A group of micro-objects in a holding pen in a micro-fluidic device can be selected and moved to a staging area, from which the micro-objects can be exported from the micro-fluidic device. The micro-fluidic device can have a plurality of holding pens, and each holding pen can isolate micro-objects located in the holding pen from micro-objects located in the other holding pens or elsewhere in the micro-fluidic device. The selected group of micro-objects can comprise one or more biological cells, such as a clonal population of cells. Embodiments of the invention can thus select a particular group of clonal cells in a micro-fluidic device, move the clonal cells to a staging area, and export the clonal cells from the micro-fluidic device while maintaining the clonal nature of the exported group.
-
10.发明申请公开(公告)号：US20160158748A1
公开(公告)日：2016-06-09
申请号：US14960010
申请日：2015-12-04
Inventor： Ming-Chiang Wu , Jodi Tsu-An Loo , Shao Ning Pei , Gaetan L. Mathieu , Jian Gong , Randall D. Lowe, JR. , Justin K. Valley
IPC: B01L3/00 , G01N27/447
CPC classification number: B01L3/50273 , B01L3/502707 , B01L3/502715 , B01L3/502792 , B01L2200/06 , B01L2300/0654 , B01L2300/0816 , B01L2300/0858 , B01L2300/0877 , B01L2300/12 , B01L2300/165 , B01L2400/0427 , G01N27/44704 , G01N27/44743 , G01N27/44791
Abstract: Single-sided optoelectrowetting (SSOEW)-configured substrates are provided, as well as microfluidic devices that include such substrates. The substrates can include a planar electrode, a photoconductive (or photosensitive) layer, a dielectric layer (single-layer or composite), a mesh electrode, and a hydrophobic coating. Fluid droplets can be moved across the hydrophobic coating of such substrates in a light-actuated manner, upon the application of a suitable AC voltage potential across the substrate and the focusing of light into the photoconductive layer of the substrate in a location proximal to the droplets. Walls can be disposed upon the substrates to form the microfluidic devices. Together the walls and substrate can form a microfluidic circuit, through which droplets can be moved.
Abstract translation: 提供了单面光电注入（SSOEW）配置的基板，以及包括这种基板的微流体装置。 基板可以包括平面电极，光导（或感光）层，电介质层（单层或复合），网状电极和疏水涂层。 当在基板上施加合适的AC电压电位并且将光聚焦到基板的光电导层中时，流体液滴可以以光致致动的方式移动穿过这种基板的疏水涂层 。 壁可以设置在基底上以形成微流体装置。 壁和基底可以一起形成微流体电路，通过该微流体电路可以移动液滴。
-
-
-
-
-
-
-
-
-
Search Results
19
records
(took 0.019 seconds)
