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    Deposition sensor based on differential heat flux measurement
    1.
    发明申请
    Deposition sensor based on differential heat flux measurement 有权
    基于差热通量测量的沉积传感器

    公开(公告)号：US20050105583A1

    公开(公告)日：2005-05-19

    申请号：US10717154

    申请日：2003-11-19

    申请人： Caibin Xiao ,  David Little ,  Scott Boyette

    发明人： Caibin Xiao ,  David Little ,  Scott Boyette

    IPC分类号： G01N17/00 ,  G01N25/18 ,  G01K17/00

    CPC分类号： G01N17/008 ,  G01N25/18

    摘要： An apparatus and method for the monitoring and measurement of chemical and/or biological deposition in heat exchangers and other fluid processing vessels. The new and original sensing system includes at least two hollow fluid vessels conductively mounted across a constant heat transfer path. Thin film heat flux sensors are attached to a heat transfer surface of the vessels in order to measure changes in differential heat flux that occur when deposition begins to accumulate in the vessel. In this way, it is shown that differential heat flux measurements can be used to detect and measure the early onset of chemical and/or biological deposition.

    摘要翻译： 用于监测和测量热交换器和其它流体处理容器中的化学和/或生物沉积的装置和方法。 新的和原始的感测系统包括至少两个导电地安装在恒定传热路径上的中空流体容器。 薄膜热通量传感器连接到容器的传热表面，以便测量当沉积开始在容器中积聚时发生的差热通量的变化。 以这种方式，可以看出差示热通量测量可用于检测和测量化学和/或生物沉积的早期发生。

    SENSOR SYSTEMS FOR QUANTIFICATION OF PHYSICAL PARAMETERS, CHEMICAL AND BIOCHEMICAL VOLATILE AND NONVOLATILE COMPOUNDS IN FLUIDS
    2.
    发明申请
    SENSOR SYSTEMS FOR QUANTIFICATION OF PHYSICAL PARAMETERS, CHEMICAL AND BIOCHEMICAL VOLATILE AND NONVOLATILE COMPOUNDS IN FLUIDS 审中-公开
    用于定量流体中物理参数，化学和生物化学挥发性和非挥发性化合物的传感器系统

    公开(公告)号：US20070146715A1

    公开(公告)日：2007-06-28

    申请号：US11668061

    申请日：2007-01-29

    申请人： Radislav Potyrailo ,  Scott Boyette ,  Caibin Xiao ,  William Morris ,  Andrew Leach ,  Ronald Wroczynski

    发明人： Radislav Potyrailo ,  Scott Boyette ,  Caibin Xiao ,  William Morris ,  Andrew Leach ,  Ronald Wroczynski

    IPC分类号： G01N21/00

    CPC分类号： G01N21/5907 ,  G01N35/00069

    摘要： system and method employing a substrate for supporting a highly reproducible sensor array for producing a prerecorded standard response for quantitative analysis of physical, chemical and biochemical parameters are provided. The system includes a substrate for supporting a highly reproducible sensor array, a light source for directing light onto the sensor spot, at least one optical pickup for detecting light transmitted through or reflected from a sensor spot, the transmitted or reflected light being indicative of a concentration of a compound, and an analog-to-digital converter for quantifying an intensity of the detected light.

    摘要翻译： 提供了使用用于支持高度可重现的传感器阵列的基板的系统和方法，用于产生用于物理，化学和生物化学参数的定量分析的预先记录的标准响应。 该系统包括用于支持高度可重现的传感器阵列的基板，用于将光引导到传感器光点上的光源，用于检测透射通过传感器点或从传感器点反射的光的至少一个光学拾取器，所发射或反射的光指示 化合物的浓度，以及用于量化检测到的光的强度的模拟 - 数字转换器。

    IN-LINE FILTRATION SYSTEMS
    4.
    发明申请
    IN-LINE FILTRATION SYSTEMS 审中-公开
    在线过滤系统

    公开(公告)号：US20090057210A1

    公开(公告)日：2009-03-05

    申请号：US12193198

    申请日：2008-08-18

    申请人： Kenneth Charles Barrett ,  Scott Boyette ,  Caibin Xiao ,  Zhaoyang Wan

    发明人： Kenneth Charles Barrett ,  Scott Boyette ,  Caibin Xiao ,  Zhaoyang Wan

    IPC分类号： B01D61/58 ,  B01D35/22 ,  B01D35/157 ,  C02F1/00 ,  B01D35/30 ,  B01D36/00

    CPC分类号： B01D61/18 ,  B01D65/08 ,  B01D2315/08 ,  B01D2315/10 ,  B01D2321/2083 ,  C02F1/44 ,  C02F2303/16

    摘要： A filtration system is disclosed that uses a combination of dead end filtration across opposing membranes with a sample take-off in the middle and cross-flow to prevent cake formation on these opposing filters. In one embodiment is a system that uses opposing filters with a central collection chamber that flips flow back and forth between the sides at a frequency that minimizes filter cake formation. In another embodiment, a combination flip-flip, cross flow system is disclosed. An additional embodiment discloses an actuator valve driven sampling system, in which valves collect the cross flow/counter flow filter cake samples as they are liberated from a filter surface and a quick through filter fluid pulse loosens the sample cake from the filter material. The invention increases effective operation time, allows for continuous filtration operation without interruption, and provides filtered samples that accurately represent the concentration of macromolecular species in industrial systems.

    摘要翻译： 公开了一种过滤系统，其使用在相对的膜上的死端过滤的组合以及在中间的样品取出和交叉流动以防止在这些相对的过滤器上形成饼状物。 在一个实施例中是一种系统，其使用具有中心收集室的相对的过滤器，所述中央收集室翻转以使滤饼形成最小化的频率在侧面之间来回流动。 在另一个实施例中，公开了一种组合式翻盖式横流系统。 另外的实施例公开了一种致动器阀驱动的采样系统，其中阀门从过滤器表面释放时收集交叉流/逆流滤饼样品，并且快速通过的过滤器流体脉冲使样品滤饼从过滤材料松开。 本发明增加了有效的操作时间，允许不间断的连续过滤操作，并提供了准确表示工业系统中大分子物质浓度的过滤样品。

    Sensor systems and methods for quantification of physical parameters, chemical and biochemical volatile and nonvolatile compounds in fluids
    7.
    发明申请
    Sensor systems and methods for quantification of physical parameters, chemical and biochemical volatile and nonvolatile compounds in fluids 失效
    用于定量流体物理参数，化学和生物化学挥发性和非挥发性化合物的传感器系统和方法

    公开(公告)号：US20050111000A1

    公开(公告)日：2005-05-26

    申请号：US10723534

    申请日：2003-11-24

    申请人： Radislav Potyrailo ,  William Morris ,  Scott Boyette ,  Marc Wisnudel ,  Andrew Leach ,  Mary Stanley

    发明人： Radislav Potyrailo ,  William Morris ,  Scott Boyette ,  Marc Wisnudel ,  Andrew Leach ,  Mary Stanley

    IPC分类号： G01N21/59 ,  G01N35/00 ,  G01N21/00

    CPC分类号： G01N21/5907 ,  G01N35/00069

    摘要： A system and method employing optical disc drives for quantitative analysis of physical, chemical and biochemical parameters are provided. The system including a disc drive for supporting and rotating an optical disc including at least one sensor spot; a light source for directing light onto the sensor spot; at least one optical pickup for detecting light transmitted from the sensor spot, the transmitted light being indicative of a concentration of a compound; and an analog-to-digital converter for quantifying an intensity of the transmitted light. The method comprising the steps of preparing the optical disc with a plurality of sensor spots, the sensor spots being responsive to a compound; exposing the optical disc to a fluid; measuring intensity of transmitted light from at least one of the plurality of sensor spots; and correlating the measured intensity of transmitted light to an amount of compound exposed to the optical disc.

    摘要翻译： 提供了一种使用光盘驱动器进行物理，化学和生物化学参数定量分析的系统和方法。 该系统包括用于支撑和旋转包括至少一个传感器点的光盘的盘驱动器; 用于将光引导到传感器点上的光源; 至少一个用于检测从传感器光点传输的光的光学拾取器，所述透射光指示化合物的浓度; 以及用于量化透射光强度的模拟 - 数字转换器。 该方法包括以下步骤：准备具有多个传感器点的光盘，所述传感器点响应于化合物; 将光盘暴露于流体; 测量来自所述多个传感器光点中的至少一个的透射光的强度; 并将测得的透射光强度与暴露于光盘的化合物的量相关联。

    Process for concentrating and processing fluid samples
    9.
    发明授权
    Process for concentrating and processing fluid samples 有权
    浓缩和处理流体样品的方法

    公开(公告)号：US08158405B2

    公开(公告)日：2012-04-17

    申请号：US12215768

    申请日：2008-06-30

    申请人： Scott Boyette ,  Rong Xu ,  Jing Luo ,  Weiqing Xu ,  Jing Chen ,  Weimin Xiao ,  Tong Chen

    发明人： Scott Boyette ,  Rong Xu ,  Jing Luo ,  Weiqing Xu ,  Jing Chen ,  Weimin Xiao ,  Tong Chen

    IPC分类号： C12N1/06

    CPC分类号： C12Q1/24

    摘要： A method of treating a liquid sample having microbiological target species therein to concentrate the species and collect lysate is disclosed. The liquid sample comprises non-target microbiological particles, inorganic particles, and microbiological target species. The liquid is passed through a prefilter medium to allow the target species to pass through as filtrate and retain non-target microbiological products and inorganic particles thereon. The filtrate is contacted with a main filtration medium adapted to retain the target species thereon as retentate. The retentate is lysed to form a lysate containing target material that was enveloped within the microbiological target species. The microbiological species may comprise cell containing or viral material. Target materials comprise intracellular nucleic acids, or in the case of viral sampling, nucleic acids encased within the protein sheath or coating of the virus.

    摘要翻译： 公开了一种处理其中具有微生物靶物种的液体样品以浓缩物种并收集裂解物的方法。 液体样品包括非目标微生物颗粒，无机颗粒和微生物目标物种。 使液体通过预过滤介质，使目标物质作为滤液通过，并在其上保留非目标微生物产物和无机颗粒。 将滤液与适于将其上保留目标物质的主过滤介质接触，作为保留物。 将渗余物溶解以形成包含在微生物目标物种内的目标物质的裂解物。 微生物物种可以包含含细胞或病毒物质。 目标材料包含细胞内核酸，或者在病毒取样的情况下，包含在病毒的蛋白质鞘或涂层内的核酸。

    Process for concentrating and processing fluid samples
    10.
    发明申请
    Process for concentrating and processing fluid samples 有权
    浓缩和处理流体样品的方法

    公开(公告)号：US20090326211A1

    公开(公告)日：2009-12-31

    申请号：US12215768

    申请日：2008-06-30

    申请人： Scott Boyette ,  Rong Xu ,  Jing Luo ,  Weiqing Xu ,  Jing Chen ,  Weimin Xiao ,  Tong Chen

    发明人： Scott Boyette ,  Rong Xu ,  Jing Luo ,  Weiqing Xu ,  Jing Chen ,  Weimin Xiao ,  Tong Chen

    IPC分类号： C07H1/06 ,  C12N1/06

    CPC分类号： C12Q1/24

    摘要： A method of treating a liquid sample having microbiological target species therein to concentrate the species and collect lysate is disclosed. The liquid sample comprises non-target microbiological particles, inorganic particles, and microbiological target species. The liquid is passed through a prefilter medium to allow the target species to pass through as filtrate and retain non-target microbiological products and inorganic particles thereon. The filtrate is contacted with a main filtration medium adapted to retain the target species thereon as retentate. The retentate is lysed to form a lysate containing target material that was enveloped within the microbiological target species. The microbiological species may comprise cell containing or viral material. Target materials comprise intracellular nucleic acids, or in the case of viral sampling, nucleic acids encased within the protein sheath or coating of the virus.

    摘要翻译： 公开了一种处理其中具有微生物靶物种的液体样品以浓缩物种并收集裂解物的方法。 液体样品包括非目标微生物颗粒，无机颗粒和微生物目标物种。 使液体通过预过滤介质，使目标物质作为滤液通过，并在其上保留非目标微生物产物和无机颗粒。 将滤液与适于将其上保留目标物质的主过滤介质接触，作为保留物。 将渗余物溶解以形成包含在微生物目标物种内的目标物质的裂解物。 微生物物种可以包含含细胞或病毒物质。 目标材料包含细胞内核酸，或者在病毒取样的情况下，包含在病毒的蛋白质鞘或涂层内的核酸。