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公开(公告)号:US08591836B2
公开(公告)日:2013-11-26
申请号:US12099644
申请日:2008-04-08
IPC分类号: B01L3/00
CPC分类号: B01L3/50851 , B01L3/50825 , B01L3/50853 , B01L2300/042 , B01L2300/046 , B01L2300/0654 , B01L2300/0829 , B01L2300/0851 , B01L2300/168 , C12Q1/6806 , G01N21/0303
摘要: A cover for a biological sample well tray, comprising a cap for sealing a sample well. The cap comprises a well lens for focusing light into the sample well and collecting light from the sample. In another aspect, the cap comprises an elongate portion configured to permit incoming light to pass into the sample well and out of the sample well. Various other aspects comprise a microcard for biological material, and an apparatus for a plurality of sample well strips. A method for testing a biological sample is also provided.
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公开(公告)号:US20080194014A1
公开(公告)日:2008-08-14
申请号:US12099644
申请日:2008-04-08
IPC分类号: C12M1/34
CPC分类号: B01L3/50851 , B01L3/50825 , B01L3/50853 , B01L2300/042 , B01L2300/046 , B01L2300/0654 , B01L2300/0829 , B01L2300/0851 , B01L2300/168 , C12Q1/6806 , G01N21/0303
摘要: A cover for a biological sample well tray, comprising a cap for sealing a sample well. The cap comprises a well lens for focusing light into the sample well and collecting light from the sample. In another aspect, the cap comprises an elongate portion configured to permit incoming light to pass into the sample well and out of the sample well. Various other aspects comprise a microcard for biological material, and an apparatus for a plurality of sample well strips. A method for testing a biological sample is also provided.
摘要翻译: 用于生物样品井托盘的盖子,包括用于密封样品井的盖子。 盖包括用于将光聚焦到样品阱中并收集来自样品的光的井透镜。 在另一方面,盖包括细长部分,该细长部分被配置成允许入射光进入样品阱并从样品阱中进入。 各种其它方面包括用于生物材料的微卡,以及用于多个样品阱条的装置。 还提供了用于测试生物样品的方法。
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公开(公告)号:US08373854B2
公开(公告)日:2013-02-12
申请号:US12813389
申请日:2010-06-10
申请人: J. Michael Phillips , Kevin S. Bodner , Aldrich N. K. Lau , Steven J. Boege , Mark F. Oldham , Donald R. Sandell , David H. Tracy
发明人: J. Michael Phillips , Kevin S. Bodner , Aldrich N. K. Lau , Steven J. Boege , Mark F. Oldham , Donald R. Sandell , David H. Tracy
IPC分类号: G01N1/10
CPC分类号: G01N21/278 , B82Y15/00 , G01J1/10 , G01N21/01 , G01N21/4785 , G01N21/6452 , G01N21/76 , G01N2201/06113 , G01N2201/0612 , G01N2201/062 , G01N2201/0691 , G01N2201/0697 , Y10S977/943 , Y10S977/949
摘要: The present teachings provide for systems, and components thereof, for detecting and/or analyzing light. These systems can include, among others, optical reference standards utilizing luminophores, such as nanocrystals, for calibrating, validating, and/or monitoring light-detection systems, before, during, and/or after sample analysis.
摘要翻译: 本教导提供了用于检测和/或分析光的系统及其组件。 这些系统尤其可以包括在样品分析之前,期间和/或之后利用发光体(例如纳米晶体)用于校准,验证和/或监测光检测系统的光学参考标准。
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公开(公告)号:US20110085168A1
公开(公告)日:2011-04-14
申请号:US12813389
申请日:2010-06-10
申请人: J. Michael Phillips , Aldrich N.K. Lau , Mark F. Oldham , Kevin S. Bodner , Steven J. Boege , Donald R. Sandell , David H. Tracy
发明人: J. Michael Phillips , Aldrich N.K. Lau , Mark F. Oldham , Kevin S. Bodner , Steven J. Boege , Donald R. Sandell , David H. Tracy
CPC分类号: G01N21/278 , B82Y15/00 , G01J1/10 , G01N21/01 , G01N21/4785 , G01N21/6452 , G01N21/76 , G01N2201/06113 , G01N2201/0612 , G01N2201/062 , G01N2201/0691 , G01N2201/0697 , Y10S977/943 , Y10S977/949
摘要: The present teachings provide for systems, and components thereof, for detecting and/or analyzing light. These systems can include, among others, optical reference standards utilizing luminophores, such as nanocrystals, for calibrating, validating, and/or monitoring light-detection systems, before, during, and/or after sample analysis.
摘要翻译: 本教导提供了用于检测和/或分析光的系统及其组件。 这些系统尤其可以包括在样品分析之前,期间和/或之后利用发光体(例如纳米晶体)用于校准,验证和/或监测光检测系统的光学参考标准。
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公开(公告)号:US07742164B1
公开(公告)日:2010-06-22
申请号:US12338778
申请日:2008-12-18
申请人: J. Michael Phillips , Aldrich N. K. Lau , Mark F. Oldham , Kevin S. Bodner , Steven J. Boege , Donald R. Sandell , David H. Tracy
发明人: J. Michael Phillips , Aldrich N. K. Lau , Mark F. Oldham , Kevin S. Bodner , Steven J. Boege , Donald R. Sandell , David H. Tracy
IPC分类号: G01J1/10
CPC分类号: G01N21/278 , B82Y15/00 , G01J1/10 , G01N21/01 , G01N21/4785 , G01N21/6452 , G01N21/76 , G01N2201/06113 , G01N2201/0612 , G01N2201/062 , G01N2201/0691 , G01N2201/0697 , Y10S977/943 , Y10S977/949
摘要: The present teachings provide for systems, and components thereof, for detecting and/or analyzing light. These systems can include, among others, optical reference standards utilizing luminophores, such as nanocrystals, for calibrating, validating, and/or monitoring light-detection systems, before, during, and/or after sample analysis.
摘要翻译: 本教导提供了用于检测和/或分析光的系统及其组件。 这些系统尤其可以包括在样品分析之前,期间和/或之后利用发光体(例如纳米晶体)用于校准,验证和/或监测光检测系统的光学参考标准。
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公开(公告)号:US07480042B1
公开(公告)日:2009-01-20
申请号:US11173609
申请日:2005-06-30
申请人: J. Michael Phillips , Aldrich N. K. Lau , Mark F. Oldham , Kevin S. Bodner , Steven J. Boege , Donald R. Sandell , David H. Tracy
发明人: J. Michael Phillips , Aldrich N. K. Lau , Mark F. Oldham , Kevin S. Bodner , Steven J. Boege , Donald R. Sandell , David H. Tracy
IPC分类号: G01J1/10
CPC分类号: G01N21/278 , B82Y15/00 , G01J1/10 , G01N21/01 , G01N21/4785 , G01N21/6452 , G01N21/76 , G01N2201/06113 , G01N2201/0612 , G01N2201/062 , G01N2201/0691 , G01N2201/0697 , Y10S977/943 , Y10S977/949
摘要: Systems, and components thereof, for detecting and/or analyzing light. These systems can include, among others, optical reference standards for calibrating, validating, and/or monitoring light-detection systems, before, during, and/or after sample analysis.
摘要翻译: 系统及其组件,用于检测和/或分析光。 样品分析之前,期间和/或之后,这些系统可以包括用于校准,验证和/或监测光检测系统的光学参考标准。
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公开(公告)号:US08641987B2
公开(公告)日:2014-02-04
申请号:US10351633
申请日:2003-01-24
申请人: Donald R. Sandell
发明人: Donald R. Sandell
IPC分类号: B01L3/00
CPC分类号: C12Q1/6806 , B01L3/502707 , B01L3/50273 , B01L3/502738 , B01L3/505 , B01L7/52 , B01L2200/0689 , B01L2300/0812 , B01L2300/0816 , B01L2300/0864 , B01L2300/0887 , B01L2400/0406 , B01L2400/0481 , B01L2400/049 , B01L2400/0655 , G01N35/00009 , Y10T156/10
摘要: A sample chamber array is provided. The sample chamber array may comprise at least one reservoir in fluid communication with at least one sample chamber, and a movable portion defining the sample chamber. The reservoir is fillable with a liquid biological sample. The movable portion may be movable with respect to the remainder of the sample chamber from a first position to a second position. In the first position the movable portion is concave and the sample chamber is without biological sample. In the second position the movable portion is convex and the sample chamber comprises biological sample. The movement of the movable portion to the second position causes a pressure drop to transport the biological sample into the sample chamber from the at least one reservoir. Methods for processing a biological sample and methods of making a sample chamber array are also provided.
摘要翻译: 提供样品室阵列。 样品室阵列可以包括与至少一个样品室流体连通的至少一个储存器和限定样品室的可移动部分。 储存器可用液体生物样品填充。 可移动部分可以相对于样品室的其余部分从第一位置移动到第二位置。 在第一位置,可移动部分是凹的,样品室没有生物样品。 在第二位置,可移动部分是凸的,并且样品室包括生物样品。 可移动部分到第二位置的运动导致压力下降,以将生物样品从至少一个储存器输送到样品室中。 还提供了处理生物样品的方法和制备样品室阵列的方法。
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公开(公告)号:US07938570B2
公开(公告)日:2011-05-10
申请号:US10874144
申请日:2004-06-21
申请人: Wade Lee , Donald R. Sandell
发明人: Wade Lee , Donald R. Sandell
IPC分类号: H01R33/00
CPC分类号: F16M11/041 , F16B21/16 , F16M11/08 , F16M11/32 , F21V21/116 , F21W2131/1005
摘要: A quick-release mounting mechanism for a worklight enabling the worklight to be quickly and easily mounted on and demounted from a tripod support stand and enabling an individual worklight head to be quickly and easily mounted on and demounted from a base stand or other support member such as the handle of a spring clamp or other clamp member. The mounting mechanism includes a latch member on the worklight base or on an individual worklight head that cooperates with an actuator mounted in the support stand or other support member. The latch member is received in a hole in the support and the actuator is formed to engage a catch on the latch member when the worklight or individual worklight head is in position on the support. In particular, the actuator is mounted in the support for movement between a latching position and a release position, and the latch member and actuator are formed to engage one another when the actuator is in its latching position so as to hold the worklight or individual worklight head on the support. A spring arrangement in the support urges the actuator into its latching position, and the actuator is provided with an engagement member by which a user can urge the actuator into its release position for quick release of the worklight or the head from the support.
摘要翻译: 一种用于工作灯的快速释放安装机构,使得工作灯能够快速且容易地安装在三脚架支撑架上并从三脚架支撑架上卸下,并使单个工作灯头能够快速方便地安装在基座或其他支撑构件上或从基座或其他支撑构件 作为弹簧夹或其它夹具的手柄。 安装机构包括在工作灯基座上的单独的工作灯头上的闩锁构件,其与安装在支撑架或其他支撑构件中的致动器配合。 闩锁构件被容纳在支撑件中的孔中,并且致动器形成为当工作灯或单独的工作灯头在支撑件上就位时接合闩锁构件上的卡扣。 特别地,致动器安装在支撑件中以在闩锁位置和释放位置之间移动,并且当致动器处于其闩锁位置时,闩锁构件和致动器形成为彼此接合,以便保持工作灯或单独的工作灯 在支持上。 支撑件中的弹簧布置促使致动器进入其闩锁位置,并且致动器设置有接合构件,用户可以通过该接合构件将致动器推动到其释放位置,以将工作灯或头部从支撑件快速释放。
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公开(公告)号:US20100216227A1
公开(公告)日:2010-08-26
申请号:US12545023
申请日:2009-08-20
申请人: Donald R. Sandell
发明人: Donald R. Sandell
CPC分类号: B01L3/502715 , B01F13/0059 , B01F15/0201 , B01F15/0233 , B01L3/5025 , B01L3/502707 , B01L3/50273 , B01L3/502738 , B01L7/52 , B01L2200/0642 , B01L2300/0803 , B01L2400/0409 , G01N35/025
摘要: A rotatable sample disk configured for samples of biological material. The sample disk may include a fill chamber for storing a first biological material, a plurality of first sample chambers positioned in the sample disk farther from the rotational axis of the sample disk than the fill chamber, a plurality of second sample chambers, and a plurality of circumferential fill channels. Each of the second sample chambers may be configured to permit fluid communication with a respective first sample chamber. The plurality of circumferential fill conduits may be configured to permit transfer of the first biological material from the fill chamber to the plurality of first sample chambers upon a first rotation of the sample disk about the rotational axis. Methods of loading a plurality of sample chambers in a sample disk are also provided.
摘要翻译: 配置用于生物材料样品的可旋转样品盘。 样品盘可以包括用于存储第一生物材料的填充室,位于样品盘中比填充室更远离样品盘的旋转轴线的多个第一样品室,多个第二样品室和多个 的圆周填充通道。 每个第二样品室可以被配置为允许与相应的第一样品室的流体连通。 多个圆周填充导管可以被配置为允许在样品盘围绕旋转轴线的第一次旋转时将第一生物材料从填充室转移到多个第一样品室。 还提供了将多个样品室装载在样品盘中的方法。
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公开(公告)号:US20090239293A1
公开(公告)日:2009-09-24
申请号:US12413396
申请日:2009-03-27
申请人: Donald R. Sandell
发明人: Donald R. Sandell
IPC分类号: C12M1/22
CPC分类号: G01N35/028 , B01L3/0293 , B01L3/5025 , B01L3/5027 , B01L3/502723 , B01L3/50851 , B01L3/50853 , B01L7/52 , B01L9/523 , B01L9/56 , B01L2200/021 , B01L2200/025 , B01L2200/0605 , B01L2200/0642 , B01L2300/022 , B01L2300/044 , B01L2300/046 , B01L2300/0829 , B01L2300/0851 , B01L2300/0864 , B01L2300/1805 , B01L2400/0406 , B01L2400/0409 , B01L2400/0487 , G01N21/274 , G01N21/6452 , G01N21/648 , G01N2035/00148 , G01N2035/00356 , G01N2035/0405 , G01N2035/0425 , G01N2035/1037
摘要: A microplate having a main body portion. The main body portion having a first surface and an opposing second surface, and a groove disposed about the first surface of the main body portion. The groove separates the main body portion into an inboard section and an outboard section. A plurality of wells are formed in the inboard section of the first surface and each of the plurality of wells being sized to receive an assay therein.
摘要翻译: 具有主体部分的微孔板。 主体部分具有第一表面和相对的第二表面,以及围绕主体部分的第一表面设置的凹槽。 槽将主体部分分成内侧部分和外侧部分。 在第一表面的内侧部分中形成多个孔,并且多个孔中的每一个的尺寸被设计成在其中接收测定。
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