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公开(公告)号：US06449827B1
公开(公告)日：2002-09-17
申请号：US09686645
申请日：2000-10-10
IPC分类号： B23Q700
CPC分类号： G01N35/0099 , B25B11/005 , G01N35/04 , G01N2035/042 , H01L21/6838 , H01L21/68707 , Y10T29/49998 , Y10T29/53991
摘要： An apparatus suitable for securely gripping and holding a microplate or other containers during robotic de-lidding operations. A microplate placed on the apparatus is held by a vacuum drawn through the base thereof, allowing the lid of the microplate to be removed without movement of the plate. Afterwards, the vacuum can be discontinued and the plate removed from the apparatus.
摘要翻译： 一种适用于在机器人脱壳操作期间可靠地夹持和保持微孔板或其他容器的装置。 放置在装置上的微孔板通过其底部抽出的真空保持，允许微板的盖移除而不移动板。 之后，可以停止真空并从设备中取出板。
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公开(公告)号：US06736783B2
公开(公告)日：2004-05-18
申请号：US09808449
申请日：2001-03-14
申请人： Kevin R. Blake , Kang Cheng , Glenn A. Clarke , Gary S. Kath , Gregory W. King , Tsuei-Ju Wu
发明人： Kevin R. Blake , Kang Cheng , Glenn A. Clarke , Gary S. Kath , Gregory W. King , Tsuei-Ju Wu
IPC分类号： A61B500
CPC分类号： A61B5/15003 , A61B5/150221 , A61B5/150229 , A61B5/150389 , A61B5/150503 , A61B5/150992 , A61B5/153 , A61B5/155
摘要： An apparatus and process for automatically, repetitively sampling blood from conscious animals. The apparatus can simultaneously extract blood from a number of conscious, catherized animals at programmable time intervals. The apparatus is characterized as a system of computer controlled valves and pumps connected by tubing filled with saline solution to a catherized animal. Blood samples are collected via a cannula from the animal and placed in a fraction collector for analyses.
摘要翻译： 一种用于自动重复抽取有意识动物血液的装置和过程。 该装置可以以可编程的时间间隔同时从许多有意识的导管动物中提取血液。 该装置的特征在于计算机控制的阀和泵的系统，其通过填充有盐溶液的管道连接到导管动物。 通过来自动物的套管收集血样，并将其置于用于分析的级分收集器中。
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公开(公告)号：US20080318310A1
公开(公告)日：2008-12-25
申请号：US11664486
申请日：2005-10-07
申请人： Claude Dufresne , Gary S. Kath , Gregory W. King , Prakash S. Masurekar , Salvatore J. Siciliano , Janet M. Sigmund , Neal R. Simpson , Stephen Skwish
发明人： Claude Dufresne , Gary S. Kath , Gregory W. King , Prakash S. Masurekar , Salvatore J. Siciliano , Janet M. Sigmund , Neal R. Simpson , Stephen Skwish
IPC分类号： C12M1/26
CPC分类号： G01N35/028 , G01N2035/1037
摘要： This invention relates to an apparatus for streaking a sample on a media-coated (agar) plate in a predefined pattern utilizing a plate carousel system to house and retrieve a plate to a fixed location, a streaking mechanism having a floating stylus having a tip capable of gliding over the agar surface and depositing a sample onto the surface of the agar, a sample dispensing system and an optional wash station.
摘要翻译： 本发明涉及一种利用板转盘系统以预定图案将样品划到介质涂覆（琼脂）板上以将板固定到固定位置的装置，具有浮动触针的条纹机构具有尖端能力 在琼脂表面上滑动并将样品沉积在琼脂表面上，样品分配系统和可选的洗涤台。
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公开(公告)号：US5882601A
公开(公告)日：1999-03-16
申请号：US877986
申请日：1997-06-18
申请人： Gary S. Kath , Lihu Yang , Gregory W. King
发明人： Gary S. Kath , Lihu Yang , Gregory W. King
CPC分类号： G01N35/1079 , B01J19/0046 , B01J2219/00283 , B01J2219/00308 , B01J2219/00335 , C40B60/14 , G01N2030/185 , Y10T436/25625 , Y10T436/2575
摘要： An access port for a reaction or other fluid vessel which maintains the vessel under an inert gas atmosphere and maintains the integrity of the inert gas seal while performing filtered filling or draining operations is presented. The port uses a deflected septum sealing technique. The invention can be used for a number of laboratory and clinical operations on a variety of size and shape vessels. The combination of the appropriate vessel with this access port is very well suited for use in lab automation systems, such as automated solid phase chemical synthesis, biological screening, combinatorial chemistry and other areas where reaction chemistry is conducted.
摘要翻译： 提供用于反应或其它流体容器的进入口，其将容器保持在惰性气体气氛下并且在执行过滤的填充或排出操作时保持惰性气体密封的完整性。 港口采用偏转隔膜密封技术。 本发明可用于多种尺寸和形状的血管的多个实验室和临床操作。 适当的容器与该进出口的组合非常适用于实验室自动化系统，例如自动化固相化学合成，生物筛选，组合化学和其他进行反应化学反应的区域。
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公开(公告)号：US5536056A
公开(公告)日：1996-07-16
申请号：US283884
申请日：1994-08-01
申请人： Glenn Clarke , Gary S. Kath , Gregory W. King
发明人： Glenn Clarke , Gary S. Kath , Gregory W. King
CPC分类号： B65G47/908 , B01J19/0046 , B01L9/00 , B01J2219/00283 , B01J2219/00308 , B01J2219/004 , B01J2219/00495 , B01L9/50 , C40B60/14
摘要： An improved gripping and pinching device particularly useful with laboratory glassware and adaptable for use with a robot or automated system, is disclosed. The device uses flexible tubing as a gripper, eyedropper pincher and as a pinch valve which biases and releases test tubes, vials or the like upon removal and application of a vacuum or pressurizing means.
摘要翻译： 公开了一种改进的夹持和夹紧装置，其特别适用于实验室玻璃器皿并且适用于机器人或自动化系统。 该装置使用柔性管作为夹持器，吸管夹钳和作为夹紧阀，其在去除和施加真空或加压装置时偏压和释放试管，小瓶等。
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公开(公告)号：US5516491A
公开(公告)日：1996-05-14
申请号：US281813
申请日：1994-07-28
申请人： Gary S. Kath , Gregory W. King , Kevin Chapman
发明人： Gary S. Kath , Gregory W. King , Kevin Chapman
CPC分类号： B01L3/50255 , B01J19/0046 , B01L3/021 , B01J2219/00283 , B01J2219/00308 , B01J2219/00335 , B01J2219/00373 , B01J2219/00418 , B01J2219/00484 , B01J2219/005 , B01J2219/00547 , C40B60/14 , C40B70/00 , G01N2035/1062
摘要： A disposable transportable reactor vessel can be prepared by modifying an eye-dropper pipette. A HDPE plug is inserted in one end of the pipette to permit selective passage of fluid while preventing resin flow. The pipette is looped into the shape of a u-tube and inserted into a holder such that the pipette is axially aligned with the holder to facilitate use in a robotic system.
摘要翻译： 一次性可运输的反应器容器可以通过改变滴眼吸移管来制备。 HDPE塞子插入移液管的一端，以允许选择性地通过流体同时防止树脂流动。 移液管被环绕成U形管的形状并插入到保持器中，使得移液管与保持器轴向对准以便于在机器人系统中使用。
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公开(公告)号：US6126904A
公开(公告)日：2000-10-03
申请号：US925817
申请日：1997-09-05
申请人： Marc Zuellig , Terry Long , James Wasson , Michael J. O'Neill , Hung Ly , Bill Williams , Gary S. Kath , Gregory W. King , Brian G. Uhrig , Steven Hutchins
发明人： Marc Zuellig , Terry Long , James Wasson , Michael J. O'Neill , Hung Ly , Bill Williams , Gary S. Kath , Gregory W. King , Brian G. Uhrig , Steven Hutchins
IPC分类号： B01J4/02 , B01J19/00 , B01L3/00 , C07B39/00 , C07B61/00 , C07C45/38 , C07C45/39 , C07C45/46 , C07C45/72 , C07C201/08 , C40B40/10 , C40B40/18 , C40B50/08 , C40B60/00 , C40B60/14 , B01L11/00
CPC分类号： B01F11/0082 , B01F13/0818 , B01J19/0046 , B01J4/02 , B01L3/5025 , B01L3/50855 , C07B39/00 , B01J2219/00286 , B01J2219/00308 , B01J2219/0031 , B01J2219/00398 , B01J2219/00418 , B01J2219/00423 , B01J2219/00452 , B01J2219/00481 , B01J2219/00495 , B01J2219/00497 , B01J2219/00585 , B01J2219/0059 , B01J2219/00596 , B01J2219/00599 , B01J2219/00686 , B01J2219/00689 , B01J2219/0072 , B01J2219/00725 , B01J2219/00745 , C40B40/10 , C40B40/18 , C40B50/08 , C40B60/14
摘要： The present invention provides apparatus and methods for the synthesis of combinatorial chemical libraries. The apparatus comprises a plurality of reaction vessels having an inner surface, an outer surface, a first opening, and a second opening. An agitator is contained within each of the reaction vessels for stimulating liquid circulation within the vessels. The apparatus has a common gas line having a plurality of gas outlet ports, where each of the reaction vessels has at least one gas outlet port positioned to feed into the vessel. The apparatus also has a common liquid line having a plurality of liquid outlet ports, where each of the reaction vessels has at least one liquid outlet port positioned to feed into the vessel. Each reaction vessel also has at least one valve coupled to the second opening on the vessel.
摘要翻译： 本发明提供用于合成组合化学文库的装置和方法。 该装置包括具有内表面，外表面，第一开口和第二开口的多个反应容器。 每个反应容器内装有搅拌器，用于刺激容器内的液体循环。 该装置具有一个具有多个气体出口的公共气体管线，其中每个反应容器具有至少一个气体出口，该气体出口定位成供入容器。 该设备还具有具有多个液体出口的公共液体管线，其中每个反应容器具有至少一个液体出口端口，定位成进料到容器中。 每个反应容器还具有至少一个与容器上的第二开口连接的阀。
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公开(公告)号：US5945070A
公开(公告)日：1999-08-31
申请号：US955434
申请日：1997-10-21
申请人： Gary S. Kath , Gregory W. King
发明人： Gary S. Kath , Gregory W. King
CPC分类号： B01L3/502 , B01J19/0046 , B01J2219/00283 , B01J2219/00335 , B01J2219/00346 , B01J2219/00373 , B01J2219/00423 , C40B60/14
摘要： A filter tube for a reaction or other fluid vessel is disclosed which maintains the vessel under an inert gas atmosphere and maintains the integrity of the inert gas seal while performing filtered or unfiltered filling or filtered draining operations.
摘要翻译： 公开了用于反应或其它流体容器的过滤管，其将容器保持在惰性气体气氛下并且在执行过滤或未过滤的填充或过滤的排水操作时保持惰性气体密封的完整性。
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公开(公告)号：US5099698A
公开(公告)日：1992-03-31
申请号：US337977
申请日：1989-04-14
申请人： Gary S. Kath , Gregory W. King
发明人： Gary S. Kath , Gregory W. King
摘要： An electronic readout for a rotameter flow gauge which includes means for optically scanning a rotameter flow gauge and determining the position of a float within the rotameter.
摘要翻译： 用于转子流量计的电子读数器，其包括用于光学扫描转子流量计并确定浮子在转子流量计内的位置的装置。
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公开(公告)号：US20090282913A1
公开(公告)日：2009-11-19
申请号：US10536120
申请日：2006-05-05
摘要： Disclosed is an improved method for measuring the volume of an animal paw, suitable for use in a rat paw edema assay. Also disclosed is a novel apparatus for measuring the volume of liquid displaced by the insertion of an object into a liquid filled cup (1) which is on a cup holder basin (3), the liquid filled cup and cup holder basin being inside a rectangular support assembly (5), the measurement obtained by determining the buoyant force produced as a result of the displacement of the liquid by the animal paw.
摘要翻译： 公开了一种用于测量适合用于大鼠爪水肿测定的动物爪的体积的改进方法。 还公开了一种用于测量通过将物体插入杯架（3）中的装满液体的杯（1）而移位的液体的体积的新型装置，所述充满液体的杯和杯保持器盆在矩形内 支撑组件（5），通过确定由于动物爪的液体的移位而产生的浮力而获得的测量值。
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