公开(公告)号：US07845473B2

公开(公告)日：2010-12-07

申请号：US11219221

申请日：2005-09-02

申请人： Hiroaki Tomita ,  Makoto Toda ,  Naoki Takayanagi

发明人： Hiroaki Tomita ,  Makoto Toda ,  Naoki Takayanagi

IPC分类号： F16D65/14

CPC分类号： F16D55/22655 ,  F16D55/00 ,  F16D55/227 ,  F16D2121/02

摘要： A brake caliper structure of a straddle seat off-load vehicle includes a brake caliper having a caliper bracket, a caliper assembly connected to the caliper bracket by two connecting portions so that the caliper assembly can move relative to the caliper bracket to clamp a brake disc. One connecting portion includes a slide pin connected to the caliper assembly and slidably received in a guide hole in the caliper bracket for effectively guiding movement of the caliper assembly relative to the caliper bracket, and the other connecting portion includes a connecting screw as a fixed pin secured to the caliper bracket, and a rubber bushing as an elastic member disposed between the caliper assembly and the fixed pin for taking up the tilting of the brake disc.

摘要翻译： 跨骑式座椅卸载车辆的制动钳结构包括具有卡钳支架的制动钳，卡钳组件通过两个连接部分连接到卡钳支架，使得卡钳组件可相对于卡钳托架移动以夹紧制动盘 。 一个连接部分包括连接到卡钳组件的滑动销，并可滑动地容纳在卡钳托架中的导向孔中，用于有效地引导卡钳组件相对于卡钳支架的运动，而另一个连接部分包括连接螺钉作为固定销 固定到卡钳支架上，以及橡胶衬套，作为设置在卡钳组件和固定销之间的弹性构件，用于卷取制动盘的倾斜。

公开(公告)号：US07644939B2

公开(公告)日：2010-01-12

申请号：US11892906

申请日：2007-08-28

申请人： Hiroaki Tomita

发明人： Hiroaki Tomita

IPC分类号： B62D5/04

CPC分类号： B62D1/16 ,  B62K5/01 ,  B62K5/08

摘要： To reduce space occupied by a handlebar stopper structure of a vehicle and to lower the cost of the handlebar stopper structure. A steering shaft is attached to an input shaft provided at an upper portion of an electric power steering unit with an output shaft provided at a lower portion of the electric power steering unit being coupled to the wheel-side. An upper handlebar stopper for regulating a turning angle of the steering shaft is provided between the steering shaft and a housing that is provided at an upper portion of the electric power steering unit. The upper handlebar stopper is configured by an orthogonally-projecting member projecting in the orthogonal direction relative to and from the steering shaft and axially-projecting parts projecting in the axial direction of the steering shaft from the housing in order to regulate the turning of the orthogonally-projecting member.

摘要翻译： 为了减少车辆的把手挡块结构所占据的空间并且降低车把挡块结构的成本。 转向轴安装在设置在电动助力转向装置的上部的输入轴上，输出轴设置在电动助力转向单元的与轮侧相连的下部。 在转向轴和设置在电动动力转向单元的上部的壳体之间设置有用于调节转向轴的转向角的上把手止动件。 上手柄止动器由正交突出构件构成，该正交突出构件相对于转向轴和从转动轴沿转向轴的轴向突出的轴向突出部分沿正交方向突出，以便调节正交的转动 项目成员。

公开(公告)号：US07022480B1

公开(公告)日：2006-04-04

申请号：US10269503

申请日：2002-10-11

申请人： J. Jay Gargus ,  K. George Chandy ,  Vikram Shakkottai ,  Hiroaki Tomita

发明人： J. Jay Gargus ,  K. George Chandy ,  Vikram Shakkottai ,  Hiroaki Tomita

IPC分类号： C12Q1/68 ,  C12N15/867 ,  C12N5/02

CPC分类号： C07K14/705

摘要： The present invention is based on the discovery and cloning of two variants of the small conductance calcium activated potassium channel type 3 (hKCa3/KCNN3) gene. The isoform variants are identical to the structure of the SKCa3-1a transcript with regard to exons 2–8, but differ in that one variant, SKCa3-1b, contains exon 1b in place of exon 1a and in that the other variant, SKCa3-1c, contains exon 1c in place of exon 1a. When expressed simultaneously with SKCa3-1a, the variants will independently dominantly negatively suppress SKCa3-1a and other functional members of the SKCa channel family. Accordingly, the present invention provides the novel gene variants, methods for the detection of the variants and treatment of disorders related to the activity of these variants. Kits employing the methods of the invention are also described.

摘要翻译： 本发明基于小电导钙激活钾通道3型（hKCa3 / KCNN3）基因的两个变体的发现和克隆。 异构体变体与外显子2-8的SKCa3-1a转录物的结构相同，但不同之处在于，一个变体SKCa3-1b含有外显子1b代替外显子1a，而另一个变体SKCa3- 1c，含有外显子1c代替外显子1a。 当与SKCa3-1a同时表达时，变体将独立地主要负面地抑制SKCa3-1a和SKCa3通道家族的其它功能成员。 因此，本发明提供了新的基因变体，检测变体的方法和治疗与这些变体的活性有关的紊乱。 还描述了采用本发明方法的试剂盒。

公开(公告)号：US20100130000A1

公开(公告)日：2010-05-27

申请号：US12591491

申请日：2009-11-20

申请人： Kazuyuki Sutou ,  Hiroaki Tomita

发明人： Kazuyuki Sutou ,  Hiroaki Tomita

IPC分类号： H01L21/60

CPC分类号： H01L24/11 ,  H01L24/03 ,  H01L24/05 ,  H01L2224/0401 ,  H01L2224/05027 ,  H01L2224/05124 ,  H01L2224/05147 ,  H01L2224/05572 ,  H01L2224/05644 ,  H01L2224/05655 ,  H01L2224/1132 ,  H01L2224/11849 ,  H01L2224/13022 ,  H01L2224/131 ,  H01L2924/00013 ,  H01L2924/0002 ,  H01L2924/01005 ,  H01L2924/01006 ,  H01L2924/01013 ,  H01L2924/01029 ,  H01L2924/01033 ,  H01L2924/01078 ,  H01L2924/01079 ,  H01L2924/01082 ,  H01L2924/014 ,  H01L2924/00014 ,  H01L2924/01014 ,  H01L2224/13099 ,  H01L2224/05099 ,  H01L2224/13599 ,  H01L2224/05599 ,  H01L2224/29099 ,  H01L2224/29599 ,  H01L2224/05552

摘要： When a bump electrode is formed on an opening formed in a semiconductor substrate, the invention prevents a void that is caused by gas trapped in the opening. A method of manufacturing a semiconductor device of the invention includes forming a first wiring on a main surface of a semiconductor substrate, forming an opening in the semiconductor substrate from the back surface to the main surface so as to expose the back surface of the first wiring, forming a second wiring connected to the back surface of the first wiring and extending from inside the opening onto the back surface of the semiconductor substrate, forming a solder layer connected to part of the second wiring on the bottom of the opening and extending from inside the opening onto the back surface of the semiconductor substrate, and forming a bump electrode on the opening by reflowing the solder layer.

摘要翻译： 当在形成在半导体衬底中的开口上形成凸起电极时，本发明防止了由开口中的气体引起的空隙。 一种制造本发明的半导体器件的方法包括在半导体衬底的主表面上形成第一布线，在半导体衬底中形成从背面到主表面的开口，以露出第一布线的背面 形成与所述第一布线的背面连接并从所述开口的内部延伸到所述半导体基板的背面的第二布线，形成与所述开口的底部的所述第二布线的一部分连接并从所述第二布线的内侧延伸的焊料层 开口到半导体衬底的背面，并且通过回流焊料层在开口上形成凸块电极。

公开(公告)号：US07687235B2

公开(公告)日：2010-03-30

申请号：US11396050

申请日：2006-03-31

申请人： Huda Akil ,  Mary Atz ,  William E. Bunney, Jr. ,  William Byerley ,  Kathleen Casey ,  Prabhakara V. Choudary ,  Simon J. Evans ,  Edward G. Jones ,  Jun Li ,  Juan F. Lopez ,  Richard M. Myers ,  Brandi Rollins ,  Robert C. Thompson ,  Hiroaki Tomita ,  Marquis P. Vawter ,  Stanley J. Watson

发明人： Huda Akil ,  Mary Atz ,  William E. Bunney, Jr. ,  William Byerley ,  Kathleen Casey ,  Prabhakara V. Choudary ,  Simon J. Evans ,  Edward G. Jones ,  Jun Li ,  Juan F. Lopez ,  Richard M. Myers ,  Brandi Rollins ,  Robert C. Thompson ,  Hiroaki Tomita ,  Marquis P. Vawter ,  Stanley J. Watson

IPC分类号： C12Q1/68 ,  C12P19/34

CPC分类号： G01N33/6893 ,  C12Q1/6883 ,  C12Q2600/136 ,  C12Q2600/156 ,  C12Q2600/158 ,  G01N33/573 ,  G01N33/6896 ,  G01N2500/00 ,  G01N2500/04 ,  G01N2800/28 ,  G01N2800/30 ,  G01N2800/302 ,  G01N2800/304

摘要： The present invention provides methods for diagnosing mental disorders (e.g., psychotic disorders such as schizophrenia and mood disorders such as major depression disorder and bipolar disorder). The invention also provides methods of identifying modulators of such mental disorders as well as methods of using these modulators to treat patients suffering from such mental disorders.

摘要翻译： 本发明提供了用于诊断精神障碍（例如精神病性障碍如精神分裂症和情绪障碍如重性抑郁障碍和双相情感障碍）的方法。 本发明还提供鉴定这种精神障碍的调节剂的方法以及使用这些调节剂来治疗患有这种精神障碍的患者的方法。

公开(公告)号：US20090233842A1

公开(公告)日：2009-09-17

申请号：US12093437

申请日：2006-11-13

申请人： Huda Akil ,  Stanley J. Watson ,  Simon J. Evans ,  Cortney Turner ,  Rene Bernard ,  Ilan Kerman ,  Robert C. Thompson ,  Margit Burmeister ,  Laura J. Scott ,  Fan Meng ,  Michael Boehnke ,  William E. Bunney, JR. ,  Marquis P. Vawter ,  Edward G. Jones ,  Prabhakara V. Choudary ,  Richard M. Myers ,  Alan F. Schatzberg ,  Jun Li ,  Devin Absher ,  Hiroaki Tomita

发明人： Huda Akil ,  Stanley J. Watson ,  Simon J. Evans ,  Cortney Turner ,  Rene Bernard ,  Ilan Kerman ,  Robert C. Thompson ,  Margit Burmeister ,  Laura J. Scott ,  Fan Meng ,  Michael Boehnke ,  William E. Bunney, JR. ,  Marquis P. Vawter ,  Edward G. Jones ,  Prabhakara V. Choudary ,  Richard M. Myers ,  Alan F. Schatzberg ,  Jun Li ,  Devin Absher ,  Hiroaki Tomita

IPC分类号： A61K38/00 ,  C12Q1/68

CPC分类号： C12Q1/6883 ,  A61K38/03 ,  A61K38/10 ,  A61K38/1774 ,  A61K38/1825 ,  C12Q2600/106 ,  C12Q2600/136 ,  C12Q2600/158 ,  G01N33/5023 ,  G01N2800/304

摘要： The present application relates to the treatment and diagnosis of mood disorders, including bipolar disorder, major depression disorder and schizophrenia. The invention provides novel diagnostic markers and assays, as well as research tools for the development and discovery of agents and compounds which are useful for treating patients who suffer from mental illness.

摘要翻译： 本申请涉及心理障碍的治疗和诊断，包括双相情感障碍，重症抑郁障碍和精神分裂症。 本发明提供了新的诊断标记和测定，以及用于开发和发现可用于治疗患有精神疾病的患者的药剂和化合物的研究工具。

公开(公告)号：US20080179853A1

公开(公告)日：2008-07-31

申请号：US11978726

申请日：2007-10-30

申请人： Naoki Kuwabara ,  Hiroaki Tomita

发明人： Naoki Kuwabara ,  Hiroaki Tomita

IPC分类号： B60G3/20

CPC分类号： B60G3/20 ,  B60G7/001 ,  B60G2200/144 ,  B60G2204/148 ,  B60G2206/012 ,  B60G2206/8201 ,  B60G2300/12 ,  B60G2300/13

摘要： A suspension arm and cushion support structure for a vehicle. A knuckle support part of a rear suspension arm is formed of a plate member extended to the vehicle body inner side relative to a rim of a wheel element so as to cover the lower side of a boot covering a connected part between a drive shaft and a universal joint. The knuckle is supported by the rear suspension arm, and rotatably supports a wheel of the vehicle. A cushion is provided for absorbing shocks transmitted to the wheel, the lower end of the cushion being coaxially supported on the knuckle support part of a lower part of the rear suspension arm.

摘要翻译： 一种用于车辆的悬架臂和坐垫支撑结构。 后悬挂臂的转向节支撑部分由相对于车轮元件的边缘延伸到车体内侧的板构件形成，以覆盖罩的下侧，覆盖驱动轴和驱动轴之间的连接部分 万向节。 转向节由后悬架臂支撑，并可旋转地支撑车辆的车轮。 设置有用于吸收传递到车轮的冲击的衬垫，衬垫的下端同轴地支撑在后悬架臂的下部的转向节支撑部分上。

公开(公告)号：US20070074928A1

公开(公告)日：2007-04-05

申请号：US11527617

申请日：2006-09-27

申请人： Megumu Okada ,  Keita Yagi ,  Yotaro Mori ,  Takeshi Wakabayashi ,  Kihoko Kaita ,  Hiroaki Tomita

发明人： Megumu Okada ,  Keita Yagi ,  Yotaro Mori ,  Takeshi Wakabayashi ,  Kihoko Kaita ,  Hiroaki Tomita

IPC分类号： B62D5/04

CPC分类号： B62D5/04 ,  B62K5/01 ,  B62K5/08

摘要： To make an electrically-operated power steering unit less susceptible to influence of change in a positional relationship between supporting sections respectively at the two ends of the electrically-operated power steering unit. A gear case included in a electrically-operated power steering unit is attached to the lower section of a vehicle body frame, and the lower end portion of a steering shaft is rotatably supported by a housing annexed to the gear case with an upper bearing interposed in between, in a vehicle in which an input shaft provided to the electrically-operated power steering unit is linked to the lower end portion of the steering shaft, and in which an output shaft provided to the electrically-operated power steering unit is rotatably supported by the lower section of a vehicle body.

摘要翻译： 为了使电动动力转向装置不易受分别在电动动力转向装置的两端的支撑部之间的位置关系变化的影响。 包括在电动动力转向单元中的齿轮箱被安装在车体框架的下部，并且转向轴的下端部由附接到齿轮箱的壳体可旋转地支撑，上轴承插入 在其中设置到电动助力转向单元的输入轴连接到转向轴的下端部的车辆中，并且其中设置到电动动力转向单元的输出轴被可旋转地支撑在其中 车身的下部。

公开(公告)号：US20050209181A1

公开(公告)日：2005-09-22

申请号：US10982556

申请日：2004-11-04

申请人： Huda Akil ,  Mary Atz ,  William Bunney ,  Prabhakara Choudary ,  Simon Evans ,  Edward Jones ,  Jun Li ,  Juan Lopez ,  Richard Myers ,  Robert Thompson ,  Hiroaki Tomita ,  Marquis Vawter ,  Stanley Watson

发明人： Huda Akil ,  Mary Atz ,  William Bunney ,  Prabhakara Choudary ,  Simon Evans ,  Edward Jones ,  Jun Li ,  Juan Lopez ,  Richard Myers ,  Robert Thompson ,  Hiroaki Tomita ,  Marquis Vawter ,  Stanley Watson

IPC分类号： A61B20060101 ,  A61K31/519 ,  A61K48/00 ,  C12Q1/68

CPC分类号： A61K31/519 ,  A61K31/7088 ,  G01N33/6893 ,  G01N2800/30 ,  G01N2800/302

摘要： The present invention provides methods for diagnosing mental disorders (e.g., psychotic disorders such as schizophrenia). The invention also provides methods of identifying modulators of such mental disorders as well as methods of using these modulators to treat patients suffering from such mental disorders.

摘要翻译： 本发明提供了用于诊断精神障碍（例如精神病性精神障碍如精神分裂症）的方法。 本发明还提供鉴定这种精神障碍的调节剂的方法以及使用这些调节剂来治疗患有这种精神障碍的患者的方法。

公开(公告)号：US06758297B2

公开(公告)日：2004-07-06

申请号：US10320378

申请日：2002-12-17

申请人： Akio Handa ,  Hiroaki Tomita ,  Shinji Goto ,  Akio Senda

发明人： Akio Handa ,  Hiroaki Tomita ,  Shinji Goto ,  Akio Senda

IPC分类号： B60K17354

CPC分类号： F16D41/067 ,  B60K17/26 ,  B60K17/35 ,  B60K23/08 ,  F16D27/10 ,  F16D41/088

摘要： A two-wheel-drive/four-wheel-drive switching system for a vehicle wherein noise is reduced and a state of drive can be securely indicated. A two-wheel-drive/four-wheel-drive switching system for a vehicle is provided with a switching unit provided to either of power transmission mechanisms connecting an engine and front wheels, and the engine and rear wheels via final reduction gear units for enabling or disabling the transmission of power in the power transmission mechanism. An indication control member is provided for detecting that the transmission of power is made in the power transmission mechanism and illuminates an indicator wherein the indication control means detects a phase difference in revolutions between a pair of final reduction gear units and illuminates or turns off the indicator when the phase difference is in a predetermined range.

摘要翻译： 一种用于车辆的二轮驱动/四轮驱动切换系统，其中噪声降低并且可以可靠地指示驱动状态。 一种用于车辆的二轮驱动/四轮驱动切换系统设置有切换单元，其设置到通过最终减速装置连接发动机和前轮以及发动机和后轮的任一功率传递机构，以使能 或禁止在动力传递机构中的动力传递。 提供一种指示控制构件，用于检测在动力传递机构中进行动力传递并照亮指示器，其中指示控制装置检测一对最终减速装置之间的转速的相位差，并且照亮或关闭指示器 当相位差处于预定范围时。