公开(公告)号：US5402955A

公开(公告)日：1995-04-04

申请号：US918591

申请日：1992-07-24

申请人： Hitoshi Takahashi ,  Hiroshi Sonobe ,  Keiichi Maeda

发明人： Hitoshi Takahashi ,  Hiroshi Sonobe ,  Keiichi Maeda

IPC分类号： G11B23/087

CPC分类号： G11B23/08721

摘要： A cassette has supply and take up reels with corresponding annular gears thereon. A pivotally mounted driving brake arm has an intermediately positioned pawl engaging the take up reel gear. An end of the driving brake arm is spaced from a coacting end of a pivotally mounted driven brake arm. An opposite end of the driven brake arm has a pawl for engaging the gear of the supply reel. When the tape is slack, the tape up reel incrementally rotates to tighten it, causing the take up reel pawl to incremental ratchet over the mating gear. This causes the driving arm to rotate and displace its end into abutting relation with the coacting end of the driven arm. Consequently, the ratchet of the driven brake arm rotates and its corresponding pawl disengages from the supply reel gear to allow the supply reel to incrementally pay out a length of tape sufficient to prevent overtightening.

摘要翻译： 盒式磁带在其上提供并卷绕有相应的环形齿轮。 枢轴安装的驱动制动臂具有接合卷取卷轴齿轮的中间位置的棘爪。 驱动制动臂的端部与枢转安装的从动制动臂的共同作用的端部间隔开。 从动制动臂的另一端具有用于接合供给卷轴的齿轮的棘爪。 当磁带松弛时，磁带卷轴逐渐旋转以使其收紧，从而使卷取卷轴棘爪在配合齿轮上增加棘轮。 这使得驱动臂旋转并将其端部移动成与从动臂的共同作用的端部邻接关系。 因此，从动制动臂的棘轮旋转并且其相应的棘爪与供带盘齿轮脱离，以允许供带盘递增地支付足以防止过紧的长度的带。

公开(公告)号：US09822387B2

公开(公告)日：2017-11-21

申请号：US14235756

申请日：2012-07-27

申请人： Ryota Fujii ,  Tomokazu Shirai ,  Tadashi Araki ,  Koh Amano ,  Yoshiko Matsumoto ,  Toshihiro Tateno ,  Nozomi Takebayashi ,  Takashi Morishige ,  Hitoshi Takahashi ,  Mitsufumi Wada ,  Hiroshi Shimizu ,  Chikara Furusawa ,  Takashi Hirasawa ,  Tomonori Hidesaki ,  Ayako Endo ,  Dominik Lukas Jürgen-Lohmann ,  Anjali Madhavan ,  Su Sun Chong

发明人： Ryota Fujii ,  Tomokazu Shirai ,  Tadashi Araki ,  Koh Amano ,  Yoshiko Matsumoto ,  Toshihiro Tateno ,  Nozomi Takebayashi ,  Takashi Morishige ,  Hitoshi Takahashi ,  Mitsufumi Wada ,  Hiroshi Shimizu ,  Chikara Furusawa ,  Takashi Hirasawa ,  Tomonori Hidesaki ,  Ayako Endo ,  Dominik Lukas Jürgen-Lohmann ,  Anjali Madhavan ,  Su Sun Chong

IPC分类号： C12N1/20 ,  C12N15/00 ,  C12N9/00 ,  C12N9/88 ,  C12N9/02 ,  C07H21/04 ,  C12P19/40 ,  C12P13/14 ,  C12N9/04 ,  C12P7/04 ,  C12P7/28 ,  C12P19/32

CPC分类号： C12P19/40 ,  C12N1/20 ,  C12N9/0006 ,  C12N9/88 ,  C12N9/93 ,  C12P7/04 ,  C12P7/28 ,  C12P13/14 ,  C12P19/32 ,  C12Y101/0106 ,  C12Y101/01081 ,  C12Y401/01047 ,  C12Y401/03024 ,  C12Y602/01009

摘要： An acetyl-CoA-producing microorganism, which is capable of efficiently synthesizing acetyl-CoA using carbon dioxide, and a substance production method using the same are provided. An acetyl-CoA-producing microorganism including an acetyl-CoA production cycle obtained by imparting at least one type of enzymatic activity selected from the group consisting of malate thiokinase, malyl-CoA lyase, glyoxylate carboligase, 2-hydroxy-3-oxopropionate reductase, and hydroxypyruvate reductase, to a microorganism.

公开(公告)号：US08834893B2

公开(公告)日：2014-09-16

申请号：US13142227

申请日：2009-12-25

申请人： Takaji Wakita ,  Tomoko Date ,  Hitoshi Takahashi

发明人： Takaji Wakita ,  Tomoko Date ,  Hitoshi Takahashi

IPC分类号： C12N15/00 ,  C12N15/11 ,  C12N15/33 ,  C12N15/51 ,  C12N7/00 ,  C07K14/005 ,  A61K39/00

CPC分类号： C07K14/005 ,  A61K2039/525 ,  C12N7/00 ,  C12N2770/24221 ,  C12N2770/24222 ,  C12N2770/24251

摘要： The present invention provides a nucleic acid comprises a 5′ untranslated region, an NS3 protein coding region, an NS4A protein coding region, an NS4B protein coding region, an NS5A protein coding region, an NS5B protein coding region, and a 3′ untranslated region of a hepatitis C virus genome, wherein the nucleic acid has nucleotide substitutions causing one or more amino acid substitutions selected from the group consisting of M(1205)K, F(1548)L, C(1615)W, T(1652)N, A(2196)T, A(2218)S, H(2223)Q, Q(2281)R, K(2520)N, and G(2374)S, as defined using the amino acid sequence shown in SEQ ID NO: 6 in the Sequence Listing as a reference sequence, in the NS3 protein coding region, the NS5A protein coding region, or the NS5B protein coding region.

摘要翻译： 本发明提供了包含5'非翻译区，NS3蛋白编码区，NS4A蛋白编码区，NS4B蛋白编码区，NS5A蛋白编码区，NS5B蛋白编码区和3'非翻译区的核酸 的丙型肝炎病毒基因组，其中所述核酸具有引起一个或多个氨基酸取代的核苷酸取代，所述氨基酸取代选自M（1205）K，F（1548）L，C（1615）W，T（1652）N ，A（2196）T，A（2218）S，H（2223）Q，Q（2281）R，K（2520）N和G（2374）S，如使用SEQ ID NO ：序列表中的6作为参考序列，在NS3蛋白编码区，NS5A蛋白编码区或NS5B蛋白编码区。

公开(公告)号：US08679800B2

公开(公告)日：2014-03-25

申请号：US13063929

申请日：2009-09-11

申请人： Takashi Morishige ,  Katsuyuki Takahashi ,  Hitoshi Takahashi ,  Mitsufumi Wada ,  Daisuke Mochizuki ,  Daisuke Miyazawa ,  Tadashi Araki

发明人： Takashi Morishige ,  Katsuyuki Takahashi ,  Hitoshi Takahashi ,  Mitsufumi Wada ,  Daisuke Mochizuki ,  Daisuke Miyazawa ,  Tadashi Araki

IPC分类号： C12P7/56 ,  C12N9/00 ,  C12N1/20 ,  C12N15/00 ,  C07H21/04

CPC分类号： C12P7/56 ,  C12N1/20 ,  C12N9/1205 ,  C12N9/2451

摘要： The present invention provides: a lactic acid-producing Escherichia coli comprising at least one gene of a sucrose non-PTS gene group, including at least a sucrose hydrolase gene, provided that a combination of a repressor protein (cscR), a sucrose hydrolase (cscA), a fructokinase (cscK) and a sucrose permease (cscB) and a combination of a sucrose hydrolase (cscA), a fructokinase (cscK) and a sucrose permease (cscB) are excluded, wherein the lactic acid-producing Escherichia coli comprises a lactic acid production enhancing system provided by genetic recombination; and a lactic acid production method including producing lactic acid from a plant-derived sucrose-containing raw material by using the lactic acid-producing Escherichia coli.

摘要翻译： 本发明提供：产生乳酸的大肠杆菌，其包含至少一个蔗糖非PTS基因组的至少一个基因，至少包含蔗糖水解酶基因，前提是阻遏蛋白（cscR），蔗糖水解酶（ cscA），果糖激酶（cscK）和蔗糖通透酶（cscB）以及蔗糖水解酶（cscA），果糖激酶（cscK）和蔗糖通透酶（cscB）的组合，其中产生乳酸的大肠杆菌包含 通过遗传重组提供的乳酸生产增强系统; 以及乳酸生产方法，其包括通过使用产生乳酸的大肠杆菌从植物来源的含蔗糖的原料生产乳酸。

公开(公告)号：US20130211170A1

公开(公告)日：2013-08-15

申请号：US13816077

申请日：2011-08-11

申请人： Koh Amano ,  Tomokazu Shirai ,  Hitoshi Takahashi ,  Junichiro Hirano ,  Yoshiko Matsumoto ,  Nozomi Takebayashi ,  Mitsufumi Wada ,  Hiroshi Shimizu ,  Chikara Furusawa ,  Takashi Hirasawa

发明人： Koh Amano ,  Tomokazu Shirai ,  Hitoshi Takahashi ,  Junichiro Hirano ,  Yoshiko Matsumoto ,  Nozomi Takebayashi ,  Mitsufumi Wada ,  Hiroshi Shimizu ,  Chikara Furusawa ,  Takashi Hirasawa

IPC分类号： C12P7/04 ,  C12P7/28 ,  C12N15/70

CPC分类号： C12P7/04 ,  C07C1/24 ,  C07C45/002 ,  C07C2529/70 ,  C07K14/245 ,  C12N9/0006 ,  C12N9/88 ,  C12N15/70 ,  C12P7/28 ,  Y02P20/52 ,  C07C11/06 ,  C07C49/08

摘要： An isopropyl alcohol-producing Escherichia coli includes an isopropyl alcohol production system, wherein an activity of transcriptional repressor GntR is inactivated, and the isopropyl alcohol-producing Escherichia coli preferably further includes a group of auxiliary enzymes having an enzyme activity expression pattern with which isopropyl alcohol production capacity achieved by the inactivation of the GntR activity is maintained or enhanced. A method of producing isopropyl alcohol includes producing isopropyl alcohol from a plant-derived raw material using the isopropyl alcohol-producing Escherichia coli. A method of producing acetone includes contacting the isopropyl alcohol obtained by the isopropyl alcohol production method with a complex oxide that includes zinc oxide and at least one oxide containing a Group 4 element, and that is prepared by coprecipitation. A method of producing propylene includes contacting isopropyl alcohol and acetone obtained by the production method with a solid acidic substance and a Cu-containing hydrogenation catalyst as catalysts.

摘要翻译： 产生异丙醇的大肠杆菌包括异丙醇生产系统，其中转录阻遏物GntR的活性被灭活，产生异丙醇的大肠杆菌优选还包括具有酶活性表达模式的一组辅酶，其中异丙醇 保持或增强GntR活性失活所产生的生产能力。 制造异丙醇的方法包括使用产生异丙醇的大肠杆菌从植物来源的原料生产异丙醇。 制造丙酮的方法包括使异丙醇制造方法得到的异丙醇与包含氧化锌和至少一种含有4族元素的氧化物复合氧化物接触，并通过共沉淀制备。 制备丙烯的方法包括使通过制备方法获得的异丙醇和丙酮与固体酸性物质和含Cu氢化催化剂作为催化剂接触。

公开(公告)号：US20130029392A1

公开(公告)日：2013-01-31

申请号：US13618898

申请日：2012-09-14

申请人： Takashi Morishige ,  Mitsufumi Wada ,  Hitoshi Takahashi ,  Daisuke Mochizuki ,  Junko Tokuda

发明人： Takashi Morishige ,  Mitsufumi Wada ,  Hitoshi Takahashi ,  Daisuke Mochizuki ,  Junko Tokuda

IPC分类号： C12P7/42

CPC分类号： C12N9/1077 ,  C12P7/42 ,  C12Y204/02011

摘要： Hydroxycarboxylic acids are produced by using a microorganism that is improved in ability to produce nicotinamide adenine dinucleotide by deleting, mutating or substituting nadR gene in the microorganism or introducing a gene encoding nicotinic acid phosphoribosyltransferase.

公开(公告)号：US08347809B2

公开(公告)日：2013-01-08

申请号：US12174867

申请日：2008-07-17

申请人： Shinya Takahashi ,  Hitoshi Takahashi

发明人： Shinya Takahashi ,  Hitoshi Takahashi

IPC分类号： B05B7/00 ,  B05D1/02

CPC分类号： B05C5/0258 ,  B01F3/04992 ,  B05C5/027 ,  B05C5/0279 ,  B29C44/461

摘要： A slot nozzle assembly for extruding a foamable melted material in a wide band including a plurality of foamable melted material passages, lateral distribution flow routes communicating with the plurality of foamable melted material passages, a restriction member disposed inside the lateral distribution flow routes, a slot for discharging foamable melted material, and a converging portion which communicates with the lateral distribution flow routes and the slot, and whose cross-section area gradually becomes smaller toward the slot.

摘要翻译： 1.一种狭缝喷嘴组件，用于在包括多个可发泡熔融材料通道的宽带中挤出可发泡熔融材料，与多个可发泡熔融材料通道连通的横向分配流动路径，设置在横向分配流动路径内的限制构件， 用于排出可发泡的熔融材料，以及与横向分配流路和槽连通并且横截面积朝向槽逐渐变小的会聚部。

公开(公告)号：US20120003720A1

公开(公告)日：2012-01-05

申请号：US13142227

申请日：2009-12-25

申请人： Takaji Wakita ,  Tomoko Date ,  Hitoshi Takahashi

发明人： Takaji Wakita ,  Tomoko Date ,  Hitoshi Takahashi

IPC分类号： C12N7/00 ,  C07K16/10 ,  C12N5/10 ,  C12N15/51 ,  C12N15/85

CPC分类号： C07K14/005 ,  A61K2039/525 ,  C12N7/00 ,  C12N2770/24221 ,  C12N2770/24222 ,  C12N2770/24251

摘要： The present invention provides a nucleic acid comprises a 5′ untranslated region, an NS3 protein coding region, an NS4A protein coding region, an NS4B protein coding region, an NS5A protein coding region, an NS5B protein coding region, and a 3′ untranslated region of a hepatitis C virus genome, wherein the nucleic acid has nucleotide substitutions causing one or more amino acid substitutions selected from the group consisting of M(1205)K, F(1548)L, C(1615)W, T(1652)N, A(2196)T, A(2218)S, H(2223)Q, Q(2281)R, K(2520)N, and G(2374)S, as defined using the amino acid sequence shown in SEQ ID NO: 6 in the Sequence Listing as a reference sequence, in the NS3 protein coding region, the NS5A protein coding region, or the NS5B protein coding region.

摘要翻译： 本发明提供了包含5'非翻译区，NS3蛋白编码区，NS4A蛋白编码区，NS4B蛋白编码区，NS5A蛋白编码区，NS5B蛋白编码区和3'非翻译区的核酸 的丙型肝炎病毒基因组，其中所述核酸具有引起一个或多个氨基酸取代的核苷酸取代，所述氨基酸取代选自M（1205）K，F（1548）L，C（1615）W，T（1652）N ，A（2196）T，A（2218）S，H（2223）Q，Q（2281）R，K（2520）N和G（2374）S，如使用SEQ ID NO ：序列表中的6作为参考序列，在NS3蛋白编码区，NS5A蛋白编码区或NS5B蛋白编码区。

公开(公告)号：US20110284917A1

公开(公告)日：2011-11-24

申请号：US12901731

申请日：2010-10-11

申请人： Michiaki Murata ,  Hiroyuki Usami ,  Yasuhisa Oota ,  Hitoshi Takahashi

发明人： Michiaki Murata ,  Hiroyuki Usami ,  Yasuhisa Oota ,  Hitoshi Takahashi

IPC分类号： H01L33/40

CPC分类号： H01L33/40 ,  H01L21/76834 ,  H01L29/452 ,  H01L33/30 ,  H01L33/62 ,  H01L2224/24 ,  H01L2924/1301 ,  H01L2924/00

摘要： A compound semiconductor device includes: an Au alloy electrode, an interlayer insulating film, a metal interconnection, and an oxide film. The Au alloy electrode is formed on a compound semiconductor. The interlayer insulating film is formed on the Au alloy electrode. The metal interconnection is connected to the Au alloy electrode via a contact hole formed in the interlayer insulating film. The oxide film is formed at an interface between the Au alloy electrode and the interlayer insulating film, dominating component of the oxide film is a constituent element of the compound semiconductor.

摘要翻译： 化合物半导体器件包括：Au合金电极，层间绝缘膜，金属互连和氧化物膜。 Au合金电极形成在化合物半导体上。 在Au合金电极上形成层间绝缘膜。 金属互连通过形成在层间绝缘膜中的接触孔连接到Au合金电极。 氧化膜形成在Au合金电极和层间绝缘膜之间的界面处，氧化膜的主要成分是化合物半导体的构成元素。

公开(公告)号：US20100311135A1

公开(公告)日：2010-12-09

申请号：US12452564

申请日：2008-07-04

申请人： Nozomi Takebayashi ,  Mitsufumi Wada ,  Daisuke Mochizuki ,  Fuminobu Yoshimi ,  Seiichi Watanabe ,  Hitoshi Takahashi ,  Takashi Morishige

发明人： Nozomi Takebayashi ,  Mitsufumi Wada ,  Daisuke Mochizuki ,  Fuminobu Yoshimi ,  Seiichi Watanabe ,  Hitoshi Takahashi ,  Takashi Morishige

IPC分类号： C12P7/04 ,  C12N1/20 ,  C12M1/107

CPC分类号： C12P7/04 ,  C12M21/12 ,  C12M47/10 ,  C12M47/20 ,  C12N9/0006 ,  C12N9/1029 ,  C12N9/13 ,  C12N9/88

摘要： The invention provides: an isopropyl alcohol-producing bacterium which has an acetoacetate decarboxylase activity, an isopropyl alcohol dehydrogenase activity, a CoA transferase activity and a thiolase activity having been imparted thereto and is capable of producing isopropyl alcohol from a plant-derived material; a method of producing isopropyl alcohol whereby isopropyl alcohol is produced from a plant-derived material by using this isopropyl alcohol-producing bacterium; and an apparatus therefor.

摘要翻译： 本发明提供：具有乙酰乙酸脱羧酶活性，异丙醇脱氢酶活性，CoA转移酶活性和硫硫酸酶活性的异丙醇生产细菌，并且能够从植物来源的材料生产异丙醇; 通过使用该异丙醇生产菌从植物来源的材料制造异丙醇的方法; 及其装置。